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The map label for this gene is betA [H]

Identifier: 160874470

GI number: 160874470

Start: 1608250

End: 1609935

Strand: Direct

Name: betA [H]

Synonym: Sbal195_1351

Alternate gene names: 160874470

Gene position: 1608250-1609935 (Clockwise)

Preceding gene: 160874469

Following gene: 160874471

Centisome position: 30.08

GC content: 48.75

Gene sequence:

>1686_bases
TTGACTCATTCACTCCAGCAAAAATATTATAACTACATCATAGTCGGCGCCGGTTCTGCAGGGTGTGTGCTCGCTAATCG
TCTGTCTAAGGATCCTAAAAACGAAGTACTGTTATTAGAAACCGGTGGCAGCGATAAGAGCATCTTTATTCAGATGCCGA
CGGCGTTATCGATTCCGATGAACAGCCCTAAATATGCTTGGCAGTTTGAGACGCAGCCTGAGCCGCATTTAGATAATCGC
AAGATGCATTGTCCTCGGGGCAAAGTGCTTGGCGGTTCATCGTCGATCAACGGCATGGTGTATGTCCGTGGTCATGCCAG
AGACTTTGATGAGTGGCAGGCACAAGGGGCGACCAATTGGGATTACAGCCATTGCTTGCCGTACTTTAAAAAGGCAGAAA
CCTGGGCCTTTGGTGGTGATGAGTATCGCGGCGAGTCTGGACCGTTAGGCGTGAATAACGGCAACCAGATGCAAAATCCA
TTATACCAAGCCTTTGTAGATGCGGGCATTGCGGCGGGGTATTTATCGACCGCCGATTATAATGCGGCGCAGCAAGAAGG
TTTTGGTCCTATGCATATGACGGTCAAAAAAGGCGTGCGTTGGTCTACCGCTAATGCTTATCTACGCCCGGCGATGGCCA
GACGTAACCTCACTGTGTTGACCCATACCTTAGTGCATAAAGTGTTATTGGAAGGGCAAGCTGCCGTTGGCGTTCGCATT
GAGCACAAAGGCAAAGTTGAAGATATTCGTTGTAATAAAGAAGTGATTTTAGCTGCTGGCTCAATAGGTTCGCCGCATTT
GTTGCAATTATCAGGCATTGGCGATCCCCAAGTATTGGCCGATGCAGGGGTCGAGTTACAACATGAGTTGCCCGGTGTCG
GTCAGAATTTACAGGATCATTTAGAGTTTTATTTCCAATTCAAATGCCTTAAACCGATTTCACTCAATGGCAAGTTAGAT
CCTTTCAGCAAGTTCTTAATCGGTGCACGGTGGATCTTAGATAAATCTGGCCTAGGGGCCACGAATCACTTTGAATCCTG
TGGTTTTATTCGCTCAAAAGCGGGCCTCGAGTGGCCAGATTTACAGTACCACTTTTTACCTGCGGCTATGCGTTACGATG
GTAAAGAAGCCTTTGCGGGGCATGGTTTTCAGGTACATGTAGGCCATAACAAGCCTAAAAGCCGTGGTGCCGTGACCTTA
GTGTCGGCAGATCCTAAAGCGCCGCCTAAGATCCAGTTCAATTATTTACAGCATCCTGATGATATTGAAGGCTTTAGAGC
CTGTGTGCGTTTGACCCGTGAGATCATCAATCAAGCGCCATTCGATGAGTATCGCGGCGAGGAAATTCAACCCGGCACAC
AAGTGCAAACCGATGAGCAAATCGATGCCTTTGTGCGTCAATCGGTTGAGAGTGCTTATCATCCTTCTTGTTCATGCAAG
ATGGGCACAGATGCGATGGCGGTAGTGGATCCTGAAACCCGCGTGCACGGCTTGCAGAATTTACGGGTAGTGGATTCTTC
TATTTTCCCGACTATCCCAAACGGCAATTTGAATGCGCCGACCATCATGTTGGCTGAGCGCGCCGCGGATATGATCTTAG
AGGCTGAGATGTTAGCGCCAGCAGATTCCGCCGTTGTGGTTGCCGACGCTTGGCAAACCACACAAAGAAGCACTGCGACA
AGTTAA

Upstream 100 bases:

>100_bases
TGGCCGTGAAAACGGTAGCGAGACACTCAAGCATTACACCCAAGTTAAAGCCGTTTACGTGGGTCTACAGCCCTTAGAAA
GCCCATTTTAAGGAGGCATT

Downstream 100 bases:

>100_bases
CGCCATAAGTGCACAACATGCCTGCTCGGTCCGTCTTATCGATGGACTGGCGGCTTCAACTTTGAAATGACTCATTAATT
GATGACTCAAAACTCATTAA

Product: choline dehydrogenase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTHSLQQKYYNYIIVGAGSAGCVLANRLSKDPKNEVLLLETGGSDKSIFIQMPTALSIPMNSPKYAWQFETQPEPHLDNR
KMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQAQGATNWDYSHCLPYFKKAETWAFGGDEYRGESGPLGVNNGNQMQNP
LYQAFVDAGIAAGYLSTADYNAAQQEGFGPMHMTVKKGVRWSTANAYLRPAMARRNLTVLTHTLVHKVLLEGQAAVGVRI
EHKGKVEDIRCNKEVILAAGSIGSPHLLQLSGIGDPQVLADAGVELQHELPGVGQNLQDHLEFYFQFKCLKPISLNGKLD
PFSKFLIGARWILDKSGLGATNHFESCGFIRSKAGLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVTL
VSADPKAPPKIQFNYLQHPDDIEGFRACVRLTREIINQAPFDEYRGEEIQPGTQVQTDEQIDAFVRQSVESAYHPSCSCK
MGTDAMAVVDPETRVHGLQNLRVVDSSIFPTIPNGNLNAPTIMLAERAADMILEAEMLAPADSAVVVADAWQTTQRSTAT
S

Sequences:

>Translated_561_residues
MTHSLQQKYYNYIIVGAGSAGCVLANRLSKDPKNEVLLLETGGSDKSIFIQMPTALSIPMNSPKYAWQFETQPEPHLDNR
KMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQAQGATNWDYSHCLPYFKKAETWAFGGDEYRGESGPLGVNNGNQMQNP
LYQAFVDAGIAAGYLSTADYNAAQQEGFGPMHMTVKKGVRWSTANAYLRPAMARRNLTVLTHTLVHKVLLEGQAAVGVRI
EHKGKVEDIRCNKEVILAAGSIGSPHLLQLSGIGDPQVLADAGVELQHELPGVGQNLQDHLEFYFQFKCLKPISLNGKLD
PFSKFLIGARWILDKSGLGATNHFESCGFIRSKAGLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVTL
VSADPKAPPKIQFNYLQHPDDIEGFRACVRLTREIINQAPFDEYRGEEIQPGTQVQTDEQIDAFVRQSVESAYHPSCSCK
MGTDAMAVVDPETRVHGLQNLRVVDSSIFPTIPNGNLNAPTIMLAERAADMILEAEMLAPADSAVVVADAWQTTQRSTAT
S
>Mature_560_residues
THSLQQKYYNYIIVGAGSAGCVLANRLSKDPKNEVLLLETGGSDKSIFIQMPTALSIPMNSPKYAWQFETQPEPHLDNRK
MHCPRGKVLGGSSSINGMVYVRGHARDFDEWQAQGATNWDYSHCLPYFKKAETWAFGGDEYRGESGPLGVNNGNQMQNPL
YQAFVDAGIAAGYLSTADYNAAQQEGFGPMHMTVKKGVRWSTANAYLRPAMARRNLTVLTHTLVHKVLLEGQAAVGVRIE
HKGKVEDIRCNKEVILAAGSIGSPHLLQLSGIGDPQVLADAGVELQHELPGVGQNLQDHLEFYFQFKCLKPISLNGKLDP
FSKFLIGARWILDKSGLGATNHFESCGFIRSKAGLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVTLV
SADPKAPPKIQFNYLQHPDDIEGFRACVRLTREIINQAPFDEYRGEEIQPGTQVQTDEQIDAFVRQSVESAYHPSCSCKM
GTDAMAVVDPETRVHGLQNLRVVDSSIFPTIPNGNLNAPTIMLAERAADMILEAEMLAPADSAVVVADAWQTTQRSTATS

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=532, Percent_Identity=51.8796992481203, Blast_Score=543, Evalue=1e-154,
Organism=Escherichia coli, GI1786503, Length=547, Percent_Identity=51.0054844606947, Blast_Score=563, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17532301, Length=557, Percent_Identity=44.8833034111311, Blast_Score=487, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24642048, Length=581, Percent_Identity=37.6936316695353, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24642055, Length=580, Percent_Identity=35.3448275862069, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24642042, Length=574, Percent_Identity=35.3658536585366, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI45551458, Length=573, Percent_Identity=34.3804537521815, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=34.5614035087719, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI17137792, Length=556, Percent_Identity=35.2517985611511, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24642039, Length=570, Percent_Identity=35.9649122807018, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24642059, Length=568, Percent_Identity=34.5070422535211, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24650267, Length=569, Percent_Identity=33.5676625659051, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24642051, Length=565, Percent_Identity=31.3274336283186, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24642037, Length=574, Percent_Identity=33.4494773519164, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI18859995, Length=569, Percent_Identity=32.3374340949033, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI18859993, Length=568, Percent_Identity=32.3943661971831, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24642035, Length=567, Percent_Identity=31.0405643738977, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24645930, Length=582, Percent_Identity=27.6632302405498, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24642057, Length=596, Percent_Identity=27.1812080536913, Blast_Score=144, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 61711; Mature: 61579

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSLQQKYYNYIIVGAGSAGCVLANRLSKDPKNEVLLLETGGSDKSIFIQMPTALSIPM
CCCHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEEECCC
NSPKYAWQFETQPEPHLDNRKMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQAQGATNW
CCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCHHHHHCCCCCC
DYSHCLPYFKKAETWAFGGDEYRGESGPLGVNNGNQMQNPLYQAFVDAGIAAGYLSTADY
CHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NAAQQEGFGPMHMTVKKGVRWSTANAYLRPAMARRNLTVLTHTLVHKVLLEGQAAVGVRI
CCHHHCCCCCEEEHHHCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEE
EHKGKVEDIRCNKEVILAAGSIGSPHLLQLSGIGDPQVLADAGVELQHELPGVGQNLQDH
ECCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCHHHHHCCCEEECCCCCCCCCHHHH
LEFYFQFKCLKPISLNGKLDPFSKFLIGARWILDKSGLGATNHFESCGFIRSKAGLEWPD
HHEEEEEEEECEEECCCCCCHHHHHHHHHHEEEECCCCCCCCCHHHCCCHHHCCCCCCCC
LQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVTLVSADPKAPPKIQFNYLQHPD
CEEEEECHHHHCCCCHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCC
DIEGFRACVRLTREIINQAPFDEYRGEEIQPGTQVQTDEQIDAFVRQSVESAYHPSCSCK
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
MGTDAMAVVDPETRVHGLQNLRVVDSSIFPTIPNGNLNAPTIMLAERAADMILEAEMLAP
CCCCEEEEECCHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCC
ADSAVVVADAWQTTQRSTATS
CCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
THSLQQKYYNYIIVGAGSAGCVLANRLSKDPKNEVLLLETGGSDKSIFIQMPTALSIPM
CCHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEEECCC
NSPKYAWQFETQPEPHLDNRKMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQAQGATNW
CCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCHHHHHCCCCCC
DYSHCLPYFKKAETWAFGGDEYRGESGPLGVNNGNQMQNPLYQAFVDAGIAAGYLSTADY
CHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NAAQQEGFGPMHMTVKKGVRWSTANAYLRPAMARRNLTVLTHTLVHKVLLEGQAAVGVRI
CCHHHCCCCCEEEHHHCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEE
EHKGKVEDIRCNKEVILAAGSIGSPHLLQLSGIGDPQVLADAGVELQHELPGVGQNLQDH
ECCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCHHHHHCCCEEECCCCCCCCCHHHH
LEFYFQFKCLKPISLNGKLDPFSKFLIGARWILDKSGLGATNHFESCGFIRSKAGLEWPD
HHEEEEEEEECEEECCCCCCHHHHHHHHHHEEEECCCCCCCCCHHHCCCHHHCCCCCCCC
LQYHFLPAAMRYDGKEAFAGHGFQVHVGHNKPKSRGAVTLVSADPKAPPKIQFNYLQHPD
CEEEEECHHHHCCCCHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCC
DIEGFRACVRLTREIINQAPFDEYRGEEIQPGTQVQTDEQIDAFVRQSVESAYHPSCSCK
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
MGTDAMAVVDPETRVHGLQNLRVVDSSIFPTIPNGNLNAPTIMLAERAADMILEAEMLAP
CCCCEEEEECCHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCC
ADSAVVVADAWQTTQRSTATS
CCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA