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The map label for this gene is tldD [H]

Identifier: 160873647

GI number: 160873647

Start: 603435

End: 604883

Strand: Direct

Name: tldD [H]

Synonym: Sbal195_0525

Alternate gene names: 160873647

Gene position: 603435-604883 (Clockwise)

Preceding gene: 160873646

Following gene: 160873648

Centisome position: 11.28

GC content: 49.62

Gene sequence:

>1449_bases
ATGCCATTTTTAGCACAAGTAGAGCAAAGTTTATTGAAGAATGGGTTAGCGTTAGAGGGTCTGCAAACCTATCTAAACAC
CATACATCAGCACAAAATCGATTATTCCGATCTCTATTTTCAAGGTAGTCGCCACGAGTCTTGGGTGCTGGAAGACGGCA
TCATTAAAGACGGTAGTTTCCATATCGAACGCGGTGTGGGCGTGCGTGCAATCAGCGGTGAAAAAACCGGTTTCGCCTAT
GCCGATGATATTACGCCAGCAGCCCTAAGCGCTGCCGCTCAGGCCGCCCGTGGCATAGCCAGTGCCGGTGAGCAAACTCA
GGTTCAAGCCTTTAAACGTCAAAAAGCCTTGGCGTTATACGACAGCTTAGATCCGATTGCGGCGATGGAAGAAGTCAAAA
AAATCAATCTGCTGAAAGAAGCCGATGCTTTTATTCGCAGTTTAGATAGCCGCATTATTCAAGTCGTTGTTAGCCTTGCA
GGCGTACACGAAGAAATCCTTATCGCTGCCAGCGATGGCACTTTAGCGGCCGATATTCGCCCTTTAGTGCGCTTTAACTG
TAGCGTGATCTTAGAAGAAAACGGTAAACGTGAACGTGGCGGCGCCGGTGGCGGTGGTCGTCATGATTACGGCGTATTAA
TGGCAAGCGATGACACAGGTTTACCTATGTGTTTTGCCTTTGCCCGCGAAGCTGTGCGCCAAGCGCAGGTCAATCTTAAT
GCTATCGATGCACCAGCGGGCGAAATGCCAGTGGTGTTAGGCAATGGCTGGCCGGGCGTATTACTCCATGAAGCAGTTGG
ACATGGTTTAGAGGGCGACTTTAACCGTAAGGGCAGCAGTGCTTTCAGCGGTAAGATGGGTCAGTTAGTCGCCTCTAAGT
TAGCGACTGTGGTCGATGATGGCACCTTGCCTAATCGTCGCGGTTCACTCAGCATTGACGATGAAGGTGTTCCGACCCAA
AGAACCGTATTGATTGAAGACGGTATTTTAAAGGGTTACATCCAAGACAAACTCAATGCTCGTTTGATGGGCGTTGCGCC
AACGGGTAATGGTCGTCGCGAATCTTACGCGCATTTACCTATGCCACGTATGACTAACACCTATATGACGGCGGGTGAGT
CGGATCCAAGCGAGATCATTAAGTCAGTGAAGAAGGGCATTTACGCCCCGAACTTTGGCGGTGGCCAAGTGGATATCACT
TCGGGTAAGTTTGTGTTCTCCGCATCCGAAGCCTATTTGATTGAAAATGGTGAAGTCACACAAGCCATTAAGGGCGCCAC
TTTAATCGGTAACGGCCCTGAGGCTATGAGCCAGATTTCTATGGTCGGTAACGATATGGCTTTAGATCAAGGTGTTGGCG
TTTGCGGTAAAGACGGTCAAAGTGTCCCTGTAGGCGTAGGCCAACCCACCTTGAAGTTAGATCGCTTAACTGTGGGTGGT
ACGGCTTAG

Upstream 100 bases:

>100_bases
CGAGCGGCAATACCGAATTAGACAGCGATTTACGTACAGAATTAGTACAGCGAATTTACACTCAGAATATCAAGATCCCT
TGGGGTCAAAGAGAGCATAG

Downstream 100 bases:

>100_bases
TATTCGTTGAGCTTGTAGATGCGCGATGGCGATAAGCGTGGTAACTGGCAAAGCTTTGTTCGGCTTTAGGCTCATATTGA
AATGTAGCTCATGCTTATTT

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MPFLAQVEQSLLKNGLALEGLQTYLNTIHQHKIDYSDLYFQGSRHESWVLEDGIIKDGSFHIERGVGVRAISGEKTGFAY
ADDITPAALSAAAQAARGIASAGEQTQVQAFKRQKALALYDSLDPIAAMEEVKKINLLKEADAFIRSLDSRIIQVVVSLA
GVHEEILIAASDGTLAADIRPLVRFNCSVILEENGKRERGGAGGGGRHDYGVLMASDDTGLPMCFAFAREAVRQAQVNLN
AIDAPAGEMPVVLGNGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKMGQLVASKLATVVDDGTLPNRRGSLSIDDEGVPTQ
RTVLIEDGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMTAGESDPSEIIKSVKKGIYAPNFGGGQVDIT
SGKFVFSASEAYLIENGEVTQAIKGATLIGNGPEAMSQISMVGNDMALDQGVGVCGKDGQSVPVGVGQPTLKLDRLTVGG
TA

Sequences:

>Translated_482_residues
MPFLAQVEQSLLKNGLALEGLQTYLNTIHQHKIDYSDLYFQGSRHESWVLEDGIIKDGSFHIERGVGVRAISGEKTGFAY
ADDITPAALSAAAQAARGIASAGEQTQVQAFKRQKALALYDSLDPIAAMEEVKKINLLKEADAFIRSLDSRIIQVVVSLA
GVHEEILIAASDGTLAADIRPLVRFNCSVILEENGKRERGGAGGGGRHDYGVLMASDDTGLPMCFAFAREAVRQAQVNLN
AIDAPAGEMPVVLGNGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKMGQLVASKLATVVDDGTLPNRRGSLSIDDEGVPTQ
RTVLIEDGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMTAGESDPSEIIKSVKKGIYAPNFGGGQVDIT
SGKFVFSASEAYLIENGEVTQAIKGATLIGNGPEAMSQISMVGNDMALDQGVGVCGKDGQSVPVGVGQPTLKLDRLTVGG
TA
>Mature_481_residues
PFLAQVEQSLLKNGLALEGLQTYLNTIHQHKIDYSDLYFQGSRHESWVLEDGIIKDGSFHIERGVGVRAISGEKTGFAYA
DDITPAALSAAAQAARGIASAGEQTQVQAFKRQKALALYDSLDPIAAMEEVKKINLLKEADAFIRSLDSRIIQVVVSLAG
VHEEILIAASDGTLAADIRPLVRFNCSVILEENGKRERGGAGGGGRHDYGVLMASDDTGLPMCFAFAREAVRQAQVNLNA
IDAPAGEMPVVLGNGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKMGQLVASKLATVVDDGTLPNRRGSLSIDDEGVPTQR
TVLIEDGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMTAGESDPSEIIKSVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIENGEVTQAIKGATLIGNGPEAMSQISMVGNDMALDQGVGVCGKDGQSVPVGVGQPTLKLDRLTVGGT
A

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=475, Percent_Identity=66.5263157894737, Blast_Score=613, Evalue=1e-176,
Organism=Escherichia coli, GI1790682, Length=410, Percent_Identity=22.9268292682927, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51011; Mature: 50879

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLAQVEQSLLKNGLALEGLQTYLNTIHQHKIDYSDLYFQGSRHESWVLEDGIIKDGSF
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCEEECCCEECCCCE
HIERGVGVRAISGEKTGFAYADDITPAALSAAAQAARGIASAGEQTQVQAFKRQKALALY
EEECCCCEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DSLDPIAAMEEVKKINLLKEADAFIRSLDSRIIQVVVSLAGVHEEILIAASDGTLAADIR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHH
PLVRFNCSVILEENGKRERGGAGGGGRHDYGVLMASDDTGLPMCFAFAREAVRQAQVNLN
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCE
AIDAPAGEMPVVLGNGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKMGQLVASKLATVVDD
EECCCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GTLPNRRGSLSIDDEGVPTQRTVLIEDGILKGYIQDKLNARLMGVAPTGNGRRESYAHLP
CCCCCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
MPRMTNTYMTAGESDPSEIIKSVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGEVT
CCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCHH
QAIKGATLIGNGPEAMSQISMVGNDMALDQGVGVCGKDGQSVPVGVGQPTLKLDRLTVGG
HHHCCCEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
TA
CC
>Mature Secondary Structure 
PFLAQVEQSLLKNGLALEGLQTYLNTIHQHKIDYSDLYFQGSRHESWVLEDGIIKDGSF
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCEEECCCEECCCCE
HIERGVGVRAISGEKTGFAYADDITPAALSAAAQAARGIASAGEQTQVQAFKRQKALALY
EEECCCCEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DSLDPIAAMEEVKKINLLKEADAFIRSLDSRIIQVVVSLAGVHEEILIAASDGTLAADIR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHH
PLVRFNCSVILEENGKRERGGAGGGGRHDYGVLMASDDTGLPMCFAFAREAVRQAQVNLN
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCE
AIDAPAGEMPVVLGNGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKMGQLVASKLATVVDD
EECCCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GTLPNRRGSLSIDDEGVPTQRTVLIEDGILKGYIQDKLNARLMGVAPTGNGRRESYAHLP
CCCCCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
MPRMTNTYMTAGESDPSEIIKSVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGEVT
CCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCHH
QAIKGATLIGNGPEAMSQISMVGNDMALDQGVGVCGKDGQSVPVGVGQPTLKLDRLTVGG
HHHCCCEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]