Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 160873646

GI number: 160873646

Start: 602491

End: 603321

Strand: Direct

Name: yafV [C]

Synonym: Sbal195_0524

Alternate gene names: 160873646

Gene position: 602491-603321 (Clockwise)

Preceding gene: 160873645

Following gene: 160873647

Centisome position: 11.27

GC content: 50.06

Gene sequence:

>831_bases
ATGCACATCAGCCTGTTGCAATGTCAGAGCAGTCGCGACGTCAGCGCCAATCTGCTGTTTATCGAATCGCAGCTTAACGA
ACTCAAACGGGATGCCGATGCGCTCCATTTAGTCGTGTTGCCCGAATGCAGTTTACTGTTTGGTGGCCACGAAAGTCAGC
AACTCGCCTATGCGGGTGATGCTCATCAGAGTCCGCTCAAATCGGCGTTAAGTGCACTGGCCGCCAAATATCAGGTATTT
ATGGTGGCAGGTACTATTCCGGCGCTGGCTGAGGATGGCCGTGTCTATAGCCGCAGTTATCTGTTTGATGATAAAGGTGA
TACTTTAGGGCATTACGATAAGCTGCATCTCTTTGATGTGGATGTTGCCGATGGTACAAAGCAATATCGCGAGAGCGAAA
CCTTCTGCCCCGGTGATCACATTAGCGTTATCGATACACCTTTTGGCAAAATTGGCCTAGCCATCTGTTATGATTTACGC
TTTCCCGACTTATTTAGGGCGATGCGTCTTGCGGGGGCCGAGATCATTACCTTGCCGTCGGCCTTTACCAAAGTGACCGG
TGAAGCCCATTGGCAAGTATTGCTACAGGCAAGAGCCATTGAAACCCAATGCGTTATTCTTGCTGCAGCTCAGTGGGGAC
AGCATAACGAAGGCAGTCGTGAAACTTGGGGGCAGAGCATGATAGTCGGTCCTTGGGGCAATATTTTGGCTGAACGTAAA
ACGGGTACGGGTTGGGTGCAGGCTGAGGTCGATTTAACCGAACTGCACAGTATTCGCCGTAAAATGCCCGTGATGCAGCA
TAATCGTTTCCTTGAGCCAAGCTTGAAATAA

Upstream 100 bases:

>100_bases
CAACCTCAAGCGACGCCTTCGCCTGAAGTACCCGTCACGCCCGCCACACCAGAGAATCAGCCAGCAGTAGAACCGATTAA
GCAAATTCAGGGAGATCAGA

Downstream 100 bases:

>100_bases
CCGCCCGCACTGGCGAGCGGCAATACCGAATTAGACAGCGATTTACGTACAGAATTAGTACAGCGAATTTACACTCAGAA
TATCAAGATCCCTTGGGGTC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MHISLLQCQSSRDVSANLLFIESQLNELKRDADALHLVVLPECSLLFGGHESQQLAYAGDAHQSPLKSALSALAAKYQVF
MVAGTIPALAEDGRVYSRSYLFDDKGDTLGHYDKLHLFDVDVADGTKQYRESETFCPGDHISVIDTPFGKIGLAICYDLR
FPDLFRAMRLAGAEIITLPSAFTKVTGEAHWQVLLQARAIETQCVILAAAQWGQHNEGSRETWGQSMIVGPWGNILAERK
TGTGWVQAEVDLTELHSIRRKMPVMQHNRFLEPSLK

Sequences:

>Translated_276_residues
MHISLLQCQSSRDVSANLLFIESQLNELKRDADALHLVVLPECSLLFGGHESQQLAYAGDAHQSPLKSALSALAAKYQVF
MVAGTIPALAEDGRVYSRSYLFDDKGDTLGHYDKLHLFDVDVADGTKQYRESETFCPGDHISVIDTPFGKIGLAICYDLR
FPDLFRAMRLAGAEIITLPSAFTKVTGEAHWQVLLQARAIETQCVILAAAQWGQHNEGSRETWGQSMIVGPWGNILAERK
TGTGWVQAEVDLTELHSIRRKMPVMQHNRFLEPSLK
>Mature_276_residues
MHISLLQCQSSRDVSANLLFIESQLNELKRDADALHLVVLPECSLLFGGHESQQLAYAGDAHQSPLKSALSALAAKYQVF
MVAGTIPALAEDGRVYSRSYLFDDKGDTLGHYDKLHLFDVDVADGTKQYRESETFCPGDHISVIDTPFGKIGLAICYDLR
FPDLFRAMRLAGAEIITLPSAFTKVTGEAHWQVLLQARAIETQCVILAAAQWGQHNEGSRETWGQSMIVGPWGNILAERK
TGTGWVQAEVDLTELHSIRRKMPVMQHNRFLEPSLK

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=177, Percent_Identity=49.1525423728814, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI297632350, Length=177, Percent_Identity=49.1525423728814, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI297632348, Length=177, Percent_Identity=49.1525423728814, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI9910460, Length=272, Percent_Identity=33.8235294117647, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI297632346, Length=100, Percent_Identity=47, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786412, Length=256, Percent_Identity=28.515625, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=273, Percent_Identity=36.2637362637363, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323383, Length=276, Percent_Identity=34.0579710144928, Blast_Score=164, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322335, Length=299, Percent_Identity=34.7826086956522, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17933642, Length=273, Percent_Identity=39.9267399267399, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21355835, Length=275, Percent_Identity=33.0909090909091, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30666; Mature: 30666

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISLLQCQSSRDVSANLLFIESQLNELKRDADALHLVVLPECSLLFGGHESQQLAYAGD
CCEEEEECCCCCCCCEEEEEEHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCEEEECCC
AHQSPLKSALSALAAKYQVFMVAGTIPALAEDGRVYSRSYLFDDKGDTLGHYDKLHLFDV
CCHHHHHHHHHHHHHHEEEEEEECCCCHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEE
DVADGTKQYRESETFCPGDHISVIDTPFGKIGLAICYDLRFPDLFRAMRLAGAEIITLPS
ECCCCHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEEECCH
AFTKVTGEAHWQVLLQARAIETQCVILAAAQWGQHNEGSRETWGQSMIVGPWGNILAERK
HHHHHCCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCHHHCCCEEEECCCHHHHEECC
TGTGWVQAEVDLTELHSIRRKMPVMQHNRFLEPSLK
CCCCEEEEECCHHHHHHHHHHCCHHHCCCCCCCCCC
>Mature Secondary Structure
MHISLLQCQSSRDVSANLLFIESQLNELKRDADALHLVVLPECSLLFGGHESQQLAYAGD
CCEEEEECCCCCCCCEEEEEEHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCEEEECCC
AHQSPLKSALSALAAKYQVFMVAGTIPALAEDGRVYSRSYLFDDKGDTLGHYDKLHLFDV
CCHHHHHHHHHHHHHHEEEEEEECCCCHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEE
DVADGTKQYRESETFCPGDHISVIDTPFGKIGLAICYDLRFPDLFRAMRLAGAEIITLPS
ECCCCHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEEECCH
AFTKVTGEAHWQVLLQARAIETQCVILAAAQWGQHNEGSRETWGQSMIVGPWGNILAERK
HHHHHCCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCHHHCCCEEEECCCHHHHEECC
TGTGWVQAEVDLTELHSIRRKMPVMQHNRFLEPSLK
CCCCEEEEECCHHHHHHHHHHCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]