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The map label for this gene is csrD [H]

Identifier: 160873622

GI number: 160873622

Start: 572371

End: 574314

Strand: Direct

Name: csrD [H]

Synonym: Sbal195_0500

Alternate gene names: 160873622

Gene position: 572371-574314 (Clockwise)

Preceding gene: 160873621

Following gene: 160873623

Centisome position: 10.7

GC content: 44.14

Gene sequence:

>1944_bases
ATGAAATTCACCCGAATGTTAACTACAAAATTAACCAGCTTTTGGTTAATGTCATTAGCCGCTATTGCCTTCGTATTTTT
GCTGAGCGCTATGATGAGTTTCGTGCAGCTGACCTATAAATTTCAGCAGCAGAAAGTCGCCGAACTCGAAACTATGTTAG
TGGACCAATATCAACACCAACCCGATTGGGATTTGGAAGCTTGGCTGCCGCCCATGCTGCTCGCCTACAATGCTGTTGAT
TTTCGGCTGACCTTGAAAGATGAAGTGATCTTTGCCTATGAAGGCAATCTCACTACGCAAAATGCCATGGTGTATGACCA
TGTGTTAGATCCAAAATCTGGTCTGCGTATGCAGCTGACCTTGACCCAACCCTTCGAGCATTACACTTTTAGTTGGTATG
AAATCCTCATCCTGTTGGTCGGTGTGTTAGCTGTGGCTGCCTTAGTGCGTTTTGGCTATTTATGGTTTTCCCAGCAATTG
GATGGCATTGAAGAATTAGCCTTACGCAGTCGATTGATCTTGCAAGGTAAGCACGAGCAAGCACTCGCGACTCCCGGAAA
TGGCAAGCCAAGGCTGATTAACCGTGCTTTGACCAAGTTGTTAGAAGAATTACAAGACGCACAAAAAGAGCGCGGTCGTT
TTGACAAGTTCATTCGTTCTAATACCTTTCTCGATGCGGAAACGCGCATTGGTAATCGACTTTTCTTAAATAACCGTCTC
GACGCCCTTAGTCATAATCAGGCGATGCTCGCCCATGGGGTGATTTATTTATTAGAGATGGATGATCTGGATTTACTGCA
GCAATCCCAAGGTGAAGCGGTAACCAAAGAGTTATTAAACTCAACAGTTAACGCGATAAGCCAACTGTTACAAACCCAAG
CTAACAGTATTTTTGCCCGTCGTTCCCACAATCAATTTGCCATAGTCGTGCCGCAAATCTCGTTAATCGAAGCTGACCAA
TTTGCCAGTAAGTTGCTTAAGATATGTTTGAGCCAGCCTTTACCCGAAGTCGAGAATAGCGATAACTTTTTCCACCTCGG
ATGCGCTTATTTTACCGCAGGCGACAATGCGGCGCAGTTAATTGAAGAAGCCGATATGGCTTTGAGGGCGGCACAATTAC
AGGGTAACAGTAATTGGTTTATGTACGACAAAGGCGCGATTGATGAAGAGTTTGCTAAAGGCTCGGTGCGTTGGCGTAGC
TTTTTAGAAAACGCGTTAGTGCAAAGGCGATTCTTCCCCTTTAGCCAGCCGATAATTGATTCAGATGGTAATGAGCACCA
TAAAGAGATATTTACTCGGGCGCGGGATAATCAAGGAGCGTTAATTCGTGCCACACTGTTTATTCCAATGGCGAATAAAT
GTGGTTTAATGCCGCAAGTCGAACGGCAAATTATTGAGCGGGTATTATTGTTACTGTCGAATGAATTAGCGGACGGCGTG
TCGAATACTCAAAAAAATAAGAAATCAGCGCCACAGATATACAGTATAAATCTGAGTTTGGATTCGCTAATGAGTCGAGC
TTTTACCCAATGGCTAAAAACGACGCTGTTAGAATATCGTCATCTGACCACGCGACTGATTTTCGAAGTGTCGGAAGATA
TCGTTATTCAACATCAAGAAAAGTTGCAGCCTAAATTAGATATGATCCGTAAAATGGGCGCGAGATTATGCGTTGATCAT
GTAGGCCAGCAGGTCGTTGGCACTTACTATATTCGTGAATGTCATTTTGATTTAATTAAGCTACATAGATCGATTGTGCG
GCATATTCATTTACGCCCAGAAAACCAATTATTCATCCGTAGCTTGATTGGCGGTTTGTATCGAACGGAAGTGCAAGTTT
GTGCCGAAGGGGTTGAAGTCTTCGAAGAATGGCAGACACTGCAAATCCTTGGCGTTGGCGCAGCGCAGGGAATGTATTTC
AGTGACCCCATAGAGGCTAAGTAA

Upstream 100 bases:

>100_bases
GCCTTTTAGGTTATGCTACTGAATAATCAACGGACAACTTTGTTGTACTCCTGTTAAAATCGCACAAATAATTATAATAA
TCCTGCAGGATAGCGGATAG

Downstream 100 bases:

>100_bases
GGCAAGTGTGGTATTTGGGTGACTAATGTCGTCTTAGAGACAAATAGATCCTATTATTCACGTATTTATCTATAAAATAC
GAGTATTTGCAGCTAAACTA

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQPDWDLEAWLPPMLLAYNAVD
FRLTLKDEVIFAYEGNLTTQNAMVYDHVLDPKSGLRMQLTLTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQL
DGIEELALRSRLILQGKHEQALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFARRSHNQFAIVVPQISLIEADQ
FASKLLKICLSQPLPEVENSDNFFHLGCAYFTAGDNAAQLIEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRS
FLENALVQRRFFPFSQPIIDSDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELADGV
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQEKLQPKLDMIRKMGARLCVDH
VGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIRSLIGGLYRTEVQVCAEGVEVFEEWQTLQILGVGAAQGMYF
SDPIEAK

Sequences:

>Translated_647_residues
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQPDWDLEAWLPPMLLAYNAVD
FRLTLKDEVIFAYEGNLTTQNAMVYDHVLDPKSGLRMQLTLTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQL
DGIEELALRSRLILQGKHEQALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFARRSHNQFAIVVPQISLIEADQ
FASKLLKICLSQPLPEVENSDNFFHLGCAYFTAGDNAAQLIEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRS
FLENALVQRRFFPFSQPIIDSDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELADGV
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQEKLQPKLDMIRKMGARLCVDH
VGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIRSLIGGLYRTEVQVCAEGVEVFEEWQTLQILGVGAAQGMYF
SDPIEAK
>Mature_647_residues
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQPDWDLEAWLPPMLLAYNAVD
FRLTLKDEVIFAYEGNLTTQNAMVYDHVLDPKSGLRMQLTLTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQL
DGIEELALRSRLILQGKHEQALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFARRSHNQFAIVVPQISLIEADQ
FASKLLKICLSQPLPEVENSDNFFHLGCAYFTAGDNAAQLIEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRS
FLENALVQRRFFPFSQPIIDSDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELADGV
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQEKLQPKLDMIRKMGARLCVDH
VGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIRSLIGGLYRTEVQVCAEGVEVFEEWQTLQILGVGAAQGMYF
SDPIEAK

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=654, Percent_Identity=28.4403669724771, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI87081845, Length=266, Percent_Identity=24.812030075188, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787541, Length=438, Percent_Identity=23.7442922374429, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=25.5144032921811, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081921, Length=445, Percent_Identity=22.247191011236, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=24.4813278008299, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI226510982, Length=303, Percent_Identity=25.4125412541254, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 74191; Mature: 74191

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDWDLEAWLPPMLLAYNAVDFRLTLKDEVIFAYEGNLTTQNAMVYDHVLDPKSGLRMQLT
CCCCHHHHCCHHHHHHCCEEEEEEEECCEEEEEECCCCCCCCEEEHHHCCCCCCCEEEEE
LTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQLDGIEELALRSRLILQGKHEQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
ALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEECCCH
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFAR
HHHCCCHHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHNQFAIVVPQISLIEADQFASKLLKICLSQPLPEVENSDNFFHLGCAYFTAGDNAAQL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCHHHHH
IEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRSFLENALVQRRFFPFSQPIID
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELADGV
CCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQE
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQPKLDMIRKMGARLCVDHVGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLIGGLYRTEVQVCAEGVEVFEEWQTLQILGVGAAQGMYFSDPIEAK
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEECCCCCCC
>Mature Secondary Structure
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDWDLEAWLPPMLLAYNAVDFRLTLKDEVIFAYEGNLTTQNAMVYDHVLDPKSGLRMQLT
CCCCHHHHCCHHHHHHCCEEEEEEEECCEEEEEECCCCCCCCEEEHHHCCCCCCCEEEEE
LTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQLDGIEELALRSRLILQGKHEQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
ALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEECCCH
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFAR
HHHCCCHHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHNQFAIVVPQISLIEADQFASKLLKICLSQPLPEVENSDNFFHLGCAYFTAGDNAAQL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCHHHHH
IEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRSFLENALVQRRFFPFSQPIID
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELADGV
CCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQE
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQPKLDMIRKMGARLCVDHVGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLIGGLYRTEVQVCAEGVEVFEEWQTLQILGVGAAQGMYFSDPIEAK
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]