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The map label for this gene is mtnC [H]

Identifier: 160873217

GI number: 160873217

Start: 108669

End: 109349

Strand: Reverse

Name: mtnC [H]

Synonym: Sbal195_0091

Alternate gene names: 160873217

Gene position: 109349-108669 (Counterclockwise)

Preceding gene: 160873221

Following gene: 160873212

Centisome position: 2.04

GC content: 45.81

Gene sequence:

>681_bases
ATGGGTATCAGAGCCATAGTCGTAGACACAGCAGGCACCACGACAGACCTAAACTTTATCCAAGATGTACTATTCCCCTA
TTCTGTCAAAGCCTTACCAGACTTTTTAGAACAGAACCAACACAATGTATTGGTTGAAAACTGTATTTGTGACACCCGAG
ATATCGCCCTAGAGCCAGATGCGGACTTAGCACGCGTGACTGAAATTTTGCAGCAGTGGGTCAGCGAAGATCGTAAAGCA
ACACCACTCAAAACTCTGCAAGGCTTGATCTGGAAGCAAGGCTACGCCCATGGCGAATTTAAGGGCCATATCTTCCCTGA
CTTTATTGAAGCAGTGAAACGCTTTAGCGAACAAAATCTGCGTATTTATAGCTTTTCATCGGGTTCGGTCGATGCGCAAA
AACTGTTGTTCAGCCACAGTGACGGCGGTGATTTAACCGAGATGTTTAACGGTCATTTTGATACCCGTACCGGCAACAAA
TTAGATAAACAGGCTTACTGCAATATCCTCAACACTATCAGCTTAAGCCCTAAGCAAGTGCTGTTTGTGTCTGATGTGAT
TGAAGAATTAAAGGCTGCCGACGCTGCAGGCATGATGACCTGCCAAATGGTACGCGATAGCAAACAACGCACGGGTGAGT
TCCGCACCATCAGCAGCTTCGATGAGCTACTGATTGAATAA

Upstream 100 bases:

>100_bases
GCCCATGTGTTTGGGCGAAATAGACTAGCCAATTTAGCCAATAACGCTTAGGATCGGAGTTGCATTTTTAAGCCAACATA
TTGTGGAGTATCAAAACATT

Downstream 100 bases:

>100_bases
CGTGATTGTTGAATAACGTGATTGTTGAATAACACGATAGTCGACTCACTCAGCCAAGCTGATTTAGCCAAAATGAAAGC
GACCTTATGGTCGCTTTTTT

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKA
TPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSEQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNK
LDKQAYCNILNTISLSPKQVLFVSDVIEELKAADAAGMMTCQMVRDSKQRTGEFRTISSFDELLIE

Sequences:

>Translated_226_residues
MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKA
TPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSEQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNK
LDKQAYCNILNTISLSPKQVLFVSDVIEELKAADAAGMMTCQMVRDSKQRTGEFRTISSFDELLIE
>Mature_225_residues
GIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKAT
PLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSEQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKL
DKQAYCNILNTISLSPKQVLFVSDVIEELKAADAAGMMTCQMVRDSKQRTGEFRTISSFDELLIE

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=254, Percent_Identity=34.251968503937, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI115533232, Length=235, Percent_Identity=36.1702127659575, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6320797, Length=208, Percent_Identity=34.1346153846154, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360080, Length=237, Percent_Identity=35.8649789029536, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24644163, Length=237, Percent_Identity=35.8649789029536, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 25433; Mature: 25302

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPD
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCC
ADLARVTEILQQWVSEDRKATPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSEQNL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKLDKQAYCNILNTISLSPKQV
EEEEECCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
LFVSDVIEELKAADAAGMMTCQMVRDSKQRTGEFRTISSFDELLIE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPD
CCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCC
ADLARVTEILQQWVSEDRKATPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSEQNL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKLDKQAYCNILNTISLSPKQV
EEEEECCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
LFVSDVIEELKAADAAGMMTCQMVRDSKQRTGEFRTISSFDELLIE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA