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The map label for this gene is fmt [H]

Identifier: 160873156

GI number: 160873156

Start: 35238

End: 36194

Strand: Reverse

Name: fmt [H]

Synonym: Sbal195_0030

Alternate gene names: 160873156

Gene position: 36194-35238 (Counterclockwise)

Preceding gene: 160873157

Following gene: 160873155

Centisome position: 0.68

GC content: 50.99

Gene sequence:

>957_bases
TTGAAACCACTCAACATCATCTTTGCCGGAACACCGGATTTTGCCGCTCGCCACTTACAAGCACTGTTGAACTCACACCA
CAATGTGATTGGCGTTTACACTCAGCCCGATAGACCCGCTGGCCGCGGCAAGAAACTGACCGCCAGCCCAGTAAAAGAAC
TCGCCGTCGCCAACAATATTCCTGTGTATCAACCCGGTTCATTACGTAAAGAACCCGCGCAACAAGAACTTGCCGCGCTG
AATGCCGATATCATGGTGGTGGTTGCCTACGGTCTGATCCTGCCAAAAGTCGTATTAGATACGCCGCGTCTAGGTTGTAT
TAACGTTCACGGTTCTATTTTGCCACGCTGGCGTGGTGCCGCACCGATCCAACGCGCACTTTGGGCTGGCGACAAAGAAA
CTGGCGTGACCGTTATGCAGATGGATGTGGGTTTAGATACTGGCGATATGCTACTGAAAACCACTCTGCCGATTGAAGAT
AGCGACACCTCAGCCAGCCTTTACGAGAAATTGGCGGAACAAGGTCCTGTTGCCCTATTGCAAGCCCTCGAAGGTCTAGT
AAACGGCACCTTAGCCGCTGAAAAACAAGATGAAGCCTTAGCGAACTACGCAGAAAAACTCAGTAAAGAAGAAGCCAGAC
TCGATTGGAATAAATCTGCCCAGCAACTCTGGCAAGAAGTCCGAGCCTTTAATCCTTGGCCAGTGAGTTACTTTGAGCAC
CAAGGCAATACTATTAAAGTGTGGCAGACCCAAGTTAGTGAAACCACCAGCACAGCCGCTCCCGGCACTATTATCAGCGC
CAGCAAAAAAGGCATAGAAGTCGCCACCGCCGACGGCGTATTAACCCTGCTGAATATGCAGCTGCCGGGGAAAAAGCCGC
TCAATGTTGCCGATATTCTCAATGCTCGAGGTGAATGGTTTAGCCCGAATACTCGCCTCGCAAACGAGGCACAATAG

Upstream 100 bases:

>100_bases
AATTGTTTGTCGATTATCTGTCGCCGCTAAAACGTCAGCGGATCAAACAAAAACTTGAAAAAGCGGCCCGATTGGACGCT
AAAGAAGCATAGGATCAGAT

Downstream 100 bases:

>100_bases
TATGAACTTGCGCGCGCTGGCTGCGAAAGCCATCTTCGAAGTATTAGAAAAAGGCGTGTCACTCTCAGTGGCACTGCCAG
ATCAACAAAAGCACCTTGCC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKPLNIIFAGTPDFAARHLQALLNSHHNVIGVYTQPDRPAGRGKKLTASPVKELAVANNIPVYQPGSLRKEPAQQELAAL
NADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTVMQMDVGLDTGDMLLKTTLPIED
SDTSASLYEKLAEQGPVALLQALEGLVNGTLAAEKQDEALANYAEKLSKEEARLDWNKSAQQLWQEVRAFNPWPVSYFEH
QGNTIKVWQTQVSETTSTAAPGTIISASKKGIEVATADGVLTLLNMQLPGKKPLNVADILNARGEWFSPNTRLANEAQ

Sequences:

>Translated_318_residues
MKPLNIIFAGTPDFAARHLQALLNSHHNVIGVYTQPDRPAGRGKKLTASPVKELAVANNIPVYQPGSLRKEPAQQELAAL
NADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTVMQMDVGLDTGDMLLKTTLPIED
SDTSASLYEKLAEQGPVALLQALEGLVNGTLAAEKQDEALANYAEKLSKEEARLDWNKSAQQLWQEVRAFNPWPVSYFEH
QGNTIKVWQTQVSETTSTAAPGTIISASKKGIEVATADGVLTLLNMQLPGKKPLNVADILNARGEWFSPNTRLANEAQ
>Mature_318_residues
MKPLNIIFAGTPDFAARHLQALLNSHHNVIGVYTQPDRPAGRGKKLTASPVKELAVANNIPVYQPGSLRKEPAQQELAAL
NADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTVMQMDVGLDTGDMLLKTTLPIED
SDTSASLYEKLAEQGPVALLQALEGLVNGTLAAEKQDEALANYAEKLSKEEARLDWNKSAQQLWQEVRAFNPWPVSYFEH
QGNTIKVWQTQVSETTSTAAPGTIISASKKGIEVATADGVLTLLNMQLPGKKPLNVADILNARGEWFSPNTRLANEAQ

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=290, Percent_Identity=29.3103448275862, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI164663775, Length=333, Percent_Identity=28.2282282282282, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI21614513, Length=242, Percent_Identity=28.9256198347107, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1789683, Length=310, Percent_Identity=65.8064516129032, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1788589, Length=284, Percent_Identity=29.9295774647887, Blast_Score=127, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI133930964, Length=313, Percent_Identity=26.1980830670927, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319458, Length=279, Percent_Identity=27.5985663082437, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550868, Length=318, Percent_Identity=27.9874213836478, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571984, Length=238, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585660, Length=239, Percent_Identity=30.1255230125523, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34496; Mature: 34496

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLNIIFAGTPDFAARHLQALLNSHHNVIGVYTQPDRPAGRGKKLTASPVKELAVANNI
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
PVYQPGSLRKEPAQQELAALNADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGA
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
APIQRALWAGDKETGVTVMQMDVGLDTGDMLLKTTLPIEDSDTSASLYEKLAEQGPVALL
CHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHH
QALEGLVNGTLAAEKQDEALANYAEKLSKEEARLDWNKSAQQLWQEVRAFNPWPVSYFEH
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHC
QGNTIKVWQTQVSETTSTAAPGTIISASKKGIEVATADGVLTLLNMQLPGKKPLNVADIL
CCCEEEEEEEHHHHHHCCCCCCCEEECCCCCCEEEECCCEEEEEEECCCCCCCCCHHHHH
NARGEWFSPNTRLANEAQ
HCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPLNIIFAGTPDFAARHLQALLNSHHNVIGVYTQPDRPAGRGKKLTASPVKELAVANNI
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
PVYQPGSLRKEPAQQELAALNADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGA
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
APIQRALWAGDKETGVTVMQMDVGLDTGDMLLKTTLPIEDSDTSASLYEKLAEQGPVALL
CHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHH
QALEGLVNGTLAAEKQDEALANYAEKLSKEEARLDWNKSAQQLWQEVRAFNPWPVSYFEH
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHC
QGNTIKVWQTQVSETTSTAAPGTIISASKKGIEVATADGVLTLLNMQLPGKKPLNVADIL
CCCEEEEEEEHHHHHHCCCCCCCEEECCCCCCEEEECCCEEEEEEECCCCCCCCCHHHHH
NARGEWFSPNTRLANEAQ
HCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA