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The map label for this gene is clpB2 [H]

Identifier: 159901485

GI number: 159901485

Start: 6310727

End: 6313306

Strand: Reverse

Name: clpB2 [H]

Synonym: Haur_4974

Alternate gene names: 159901485

Gene position: 6313306-6310727 (Counterclockwise)

Preceding gene: 159901505

Following gene: 159901484

Centisome position: 99.48

GC content: 51.09

Gene sequence:

>2580_bases
ATGAATTTGAATATTTACACCGAAAAATCACGCGCAGCTATTTTTGATGCCCAAAGCATCGCTTCTCGCAACGGCCAAAG
CGAAATCACACCAGAACACGTTCTTGTGGCCTTGCTCGAACAAGCTGATGGCGTGGTTCCGCAAATTATCACCAAAATGG
ATCGCGATCCGCAGGCCTTAGTTGCTGCGGTTAATGATGAAATTCGCCGTTTGCCCCGAGTGAGTGGCACTCAAATGCAG
CCTGGCATTGGACAACGCTTAGATCAAGTATCTCAAACCGCCGAAAATGAAGCCAAAGGCATGGGCGATGAGTATGTTTC
CACCGAACATCTCTTGCTTGGCCTCGCAAGCGAACGCGCCAAAGGCCCATCGCAACGCTTGCTGACCTCGTTTGGCATTA
CCAAAGATGCGATTCTCAAAACCTTAACTGCCATCCGTGGCAATCAACGGGTCACCGACCAAAATCCCGAGGGTAAATAT
CAAGCGCTCGAAAAGTATGGCCGCGATTTAACGACGTTGGCCCAACGCGGCAAGCTTGATCCAGTCATTGGCCGCGATGA
AGAAATTCGCCGCACGATTCAGGTCCTTTCACGCCGTACCAAAAATAATCCAGTCTTAATTGGTGAGCCAGGCGTTGGTA
AAACTGCGATAGTCGAGGGCTTGGCGGCGCGGATTGTGCGCGGCGATGTGCCCGAAGCACTGCGTAACAAACGTTTGATC
GCGCTCGATTTGGGAGCGCTGGTGGCAGGCGCAAAATTTCGCGGCGAGTTTGAAGAACGGCTCAAAGCTGTGCTCAGCGA
AGTAACCTCGGCTGATGGTCGGGTAATTTTGTTTATCGATGAGTTACATACCGTGGTTGGCGCTGGTGCTGCCGAAGGCT
CGATGGATGCCTCGAATATGCTCAAGCCCGCATTGGCTCGCGGCGAACTGCACACAATCGGGGCAACCACGCTTGATGAA
TATCGCAAATATATTGAGAAAGATCCAGCATTGGAACGCCGTTTCCAACCTGTTTTGGTCGGCGAGCCAAGTGTTGAAGA
TACCATCTCGATTTTGCGCGGCTTGAAAGAACGCTACGAAACCCATCACAACGTGCGAATTACTGATGCAGCGATTGTCG
CCGCCGCAACCTTATCCAATCGCTATATCGCTGATCGCTTCTTGCCCGACAAAGCAATTGACTTAATCGACGAAGCTGCT
GCCAAACTACGCATGGAAATCACCAGCGATCCGGTTGAACTCGATGAGATCAAGCGCAAACGCATGCAATGGGAAATTGA
ACGCGAAGCCTTGAAACGCGAAAAAGATCCTGCCTCCAAGGAGCGCTTGGAGCGGCTCGAACGTGATTTGGCCAACTTGC
GCGAACAACAGGCAGTGCTCGATACCAAACTTTCCAGTGAGCGCGGCGCAATCAATGCTATCGCTCAACTCAAGGAAAAA
ATCGATCAAACCAAGGTGCAAATCGAGCAAGCTCAACGCCAATACGATTATAACCGTGCTGCCGAGTTGCAATATGGCAC
GCTCAACAGCTTAGAGCAACAACTCGGCGAGGCCGAAGCCAAAGTTCGCGATATGCAAGAACATGGTATGTTGCTCAACG
AAGAAGTCTCCGAAGAAGATATTGCTCAAGTTGTCGCCAAATGGACGGGTATTCCGGTTTCCAAGCTGTTGGAAGGCGAA
TTGCAGAAACTGGTCAAGATGGAAGAACGCTTGCATGCCCGCGTGATCGGCCAACACGAAGCGGTCAAAGCCGTTTCCGA
TGCAGTGCGACGTTCACGGGCCGGCTTGCAAGATCCCAATCGACCACTAGGTTCGTTCTTATTCCTTGGGCCAACTGGGG
TTGGTAAAACCGAGTTGGCACGGGCTTTGGCTGAATTTTTGTTCGATGACGAAGCAGCAATGGTGCGGATCGATATGTCG
GAATATATGGAGCGTCATGCCGTGGCACGGCTGATTGGTGCACCTCCAGGTTATGTTGGCTACGAAGAAGGCGGCCAATT
AACCGAGGCTGTGCGCCGTCGCCCCTATAGCGTGGTGCTGTTCGACGAAATTGAAAAAGCCCATCCCGATGTGTTCAACA
CGCTATTGCAATTGCTCGATGATGGTCGCCTGACCGATGGCCAAGGTCGGTTGGTCGATTTCACCAATACCGTGGTGATT
ATGACCTCGAACATCGGCAGTAATCGGATTCAAAGTTTGGTTGATGATGAAGAAGCGATGCGCGAAGCCGTGTTGGAAGA
ATTGCACGACGAGCTACGGCCTGAATTCCTCAACCGGATCGATGATGTGATTATCTTCAAGCCCTTGACTCAAGCTGAAA
TCAAACATATCGTCGATATTCAGGTTGATCGGCTGAGCAAACGCTTGAGCGAACGCAAACTTAAATTGGTGTTGAATGAA
GCGGCCCGTCAGCACTTAGCTCAAGTTGGCTATGACCCAGTGTTCGGCGCACGGCCACTCAAACGCGCCATCCAGAGCGA
GTTGCTCAATCCATTGGCCTTGGAAGTGCTCAAAGGTAAATTCCCAGGTGGCACAACCGTCAATGTTGATGTTAAAAATG
GCAAACTCAGTTTCGACTAA

Upstream 100 bases:

>100_bases
CATTATGTTCAGACAATCTTCTAACATTGGCCTACTATGTTTTTAACAAGGCTCTGCTATGCTAACTGCAACGACAACTG
AATAGGGAGGTTTCGCACAG

Downstream 100 bases:

>100_bases
GTGCTAGCAATCGCAGCCCTCATCAGTAGCTTGATGGGGGCTTTTGTTGGTGCGAAAAATGCCCTATACTAGCCCCATTC
AGCCAATTGTCGATGGAGCA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MNLNIYTEKSRAAIFDAQSIASRNGQSEITPEHVLVALLEQADGVVPQIITKMDRDPQALVAAVNDEIRRLPRVSGTQMQ
PGIGQRLDQVSQTAENEAKGMGDEYVSTEHLLLGLASERAKGPSQRLLTSFGITKDAILKTLTAIRGNQRVTDQNPEGKY
QALEKYGRDLTTLAQRGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAARIVRGDVPEALRNKRLI
ALDLGALVAGAKFRGEFEERLKAVLSEVTSADGRVILFIDELHTVVGAGAAEGSMDASNMLKPALARGELHTIGATTLDE
YRKYIEKDPALERRFQPVLVGEPSVEDTISILRGLKERYETHHNVRITDAAIVAAATLSNRYIADRFLPDKAIDLIDEAA
AKLRMEITSDPVELDEIKRKRMQWEIEREALKREKDPASKERLERLERDLANLREQQAVLDTKLSSERGAINAIAQLKEK
IDQTKVQIEQAQRQYDYNRAAELQYGTLNSLEQQLGEAEAKVRDMQEHGMLLNEEVSEEDIAQVVAKWTGIPVSKLLEGE
LQKLVKMEERLHARVIGQHEAVKAVSDAVRRSRAGLQDPNRPLGSFLFLGPTGVGKTELARALAEFLFDDEAAMVRIDMS
EYMERHAVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNTLLQLLDDGRLTDGQGRLVDFTNTVVI
MTSNIGSNRIQSLVDDEEAMREAVLEELHDELRPEFLNRIDDVIIFKPLTQAEIKHIVDIQVDRLSKRLSERKLKLVLNE
AARQHLAQVGYDPVFGARPLKRAIQSELLNPLALEVLKGKFPGGTTVNVDVKNGKLSFD

Sequences:

>Translated_859_residues
MNLNIYTEKSRAAIFDAQSIASRNGQSEITPEHVLVALLEQADGVVPQIITKMDRDPQALVAAVNDEIRRLPRVSGTQMQ
PGIGQRLDQVSQTAENEAKGMGDEYVSTEHLLLGLASERAKGPSQRLLTSFGITKDAILKTLTAIRGNQRVTDQNPEGKY
QALEKYGRDLTTLAQRGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAARIVRGDVPEALRNKRLI
ALDLGALVAGAKFRGEFEERLKAVLSEVTSADGRVILFIDELHTVVGAGAAEGSMDASNMLKPALARGELHTIGATTLDE
YRKYIEKDPALERRFQPVLVGEPSVEDTISILRGLKERYETHHNVRITDAAIVAAATLSNRYIADRFLPDKAIDLIDEAA
AKLRMEITSDPVELDEIKRKRMQWEIEREALKREKDPASKERLERLERDLANLREQQAVLDTKLSSERGAINAIAQLKEK
IDQTKVQIEQAQRQYDYNRAAELQYGTLNSLEQQLGEAEAKVRDMQEHGMLLNEEVSEEDIAQVVAKWTGIPVSKLLEGE
LQKLVKMEERLHARVIGQHEAVKAVSDAVRRSRAGLQDPNRPLGSFLFLGPTGVGKTELARALAEFLFDDEAAMVRIDMS
EYMERHAVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNTLLQLLDDGRLTDGQGRLVDFTNTVVI
MTSNIGSNRIQSLVDDEEAMREAVLEELHDELRPEFLNRIDDVIIFKPLTQAEIKHIVDIQVDRLSKRLSERKLKLVLNE
AARQHLAQVGYDPVFGARPLKRAIQSELLNPLALEVLKGKFPGGTTVNVDVKNGKLSFD
>Mature_859_residues
MNLNIYTEKSRAAIFDAQSIASRNGQSEITPEHVLVALLEQADGVVPQIITKMDRDPQALVAAVNDEIRRLPRVSGTQMQ
PGIGQRLDQVSQTAENEAKGMGDEYVSTEHLLLGLASERAKGPSQRLLTSFGITKDAILKTLTAIRGNQRVTDQNPEGKY
QALEKYGRDLTTLAQRGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAARIVRGDVPEALRNKRLI
ALDLGALVAGAKFRGEFEERLKAVLSEVTSADGRVILFIDELHTVVGAGAAEGSMDASNMLKPALARGELHTIGATTLDE
YRKYIEKDPALERRFQPVLVGEPSVEDTISILRGLKERYETHHNVRITDAAIVAAATLSNRYIADRFLPDKAIDLIDEAA
AKLRMEITSDPVELDEIKRKRMQWEIEREALKREKDPASKERLERLERDLANLREQQAVLDTKLSSERGAINAIAQLKEK
IDQTKVQIEQAQRQYDYNRAAELQYGTLNSLEQQLGEAEAKVRDMQEHGMLLNEEVSEEDIAQVVAKWTGIPVSKLLEGE
LQKLVKMEERLHARVIGQHEAVKAVSDAVRRSRAGLQDPNRPLGSFLFLGPTGVGKTELARALAEFLFDDEAAMVRIDMS
EYMERHAVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNTLLQLLDDGRLTDGQGRLVDFTNTVVI
MTSNIGSNRIQSLVDDEEAMREAVLEELHDELRPEFLNRIDDVIIFKPLTQAEIKHIVDIQVDRLSKRLSERKLKLVLNE
AARQHLAQVGYDPVFGARPLKRAIQSELLNPLALEVLKGKFPGGTTVNVDVKNGKLSFD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=318, Percent_Identity=38.3647798742138, Blast_Score=226, Evalue=8e-59,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=57.4418604651163, Blast_Score=959, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=279, Percent_Identity=50.179211469534, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=710, Percent_Identity=55.4929577464789, Blast_Score=780, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=867, Percent_Identity=43.1372549019608, Blast_Score=672, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95712; Mature: 95712

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNIYTEKSRAAIFDAQSIASRNGQSEITPEHVLVALLEQADGVVPQIITKMDRDPQAL
CCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
VAAVNDEIRRLPRVSGTQMQPGIGQRLDQVSQTAENEAKGMGDEYVSTEHLLLGLASERA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
KGPSQRLLTSFGITKDAILKTLTAIRGNQRVTDQNPEGKYQALEKYGRDLTTLAQRGKLD
CCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCC
PVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAARIVRGDVPEALRNKRLI
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEE
ALDLGALVAGAKFRGEFEERLKAVLSEVTSADGRVILFIDELHTVVGAGAAEGSMDASNM
EEEHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPALARGELHTIGATTLDEYRKYIEKDPALERRFQPVLVGEPSVEDTISILRGLKERYE
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHH
THHNVRITDAAIVAAATLSNRYIADRFLPDKAIDLIDEAAAKLRMEITSDPVELDEIKRK
CCCCEEEEHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RMQWEIEREALKREKDPASKERLERLERDLANLREQQAVLDTKLSSERGAINAIAQLKEK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IDQTKVQIEQAQRQYDYNRAAELQYGTLNSLEQQLGEAEAKVRDMQEHGMLLNEEVSEED
HHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IAQVVAKWTGIPVSKLLEGELQKLVKMEERLHARVIGQHEAVKAVSDAVRRSRAGLQDPN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCC
RPLGSFLFLGPTGVGKTELARALAEFLFDDEAAMVRIDMSEYMERHAVARLIGAPPGYVG
CCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCC
YEEGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNTLLQLLDDGRLTDGQGRLVDFTNTVVI
CCCCCHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEE
MTSNIGSNRIQSLVDDEEAMREAVLEELHDELRPEFLNRIDDVIIFKPLTQAEIKHIVDI
EECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHHHH
QVDRLSKRLSERKLKLVLNEAARQHLAQVGYDPVFGARPLKRAIQSELLNPLALEVLKGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
FPGGTTVNVDVKNGKLSFD
CCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MNLNIYTEKSRAAIFDAQSIASRNGQSEITPEHVLVALLEQADGVVPQIITKMDRDPQAL
CCCCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
VAAVNDEIRRLPRVSGTQMQPGIGQRLDQVSQTAENEAKGMGDEYVSTEHLLLGLASERA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
KGPSQRLLTSFGITKDAILKTLTAIRGNQRVTDQNPEGKYQALEKYGRDLTTLAQRGKLD
CCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCC
PVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAARIVRGDVPEALRNKRLI
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEE
ALDLGALVAGAKFRGEFEERLKAVLSEVTSADGRVILFIDELHTVVGAGAAEGSMDASNM
EEEHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPALARGELHTIGATTLDEYRKYIEKDPALERRFQPVLVGEPSVEDTISILRGLKERYE
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHH
THHNVRITDAAIVAAATLSNRYIADRFLPDKAIDLIDEAAAKLRMEITSDPVELDEIKRK
CCCCEEEEHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RMQWEIEREALKREKDPASKERLERLERDLANLREQQAVLDTKLSSERGAINAIAQLKEK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IDQTKVQIEQAQRQYDYNRAAELQYGTLNSLEQQLGEAEAKVRDMQEHGMLLNEEVSEED
HHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IAQVVAKWTGIPVSKLLEGELQKLVKMEERLHARVIGQHEAVKAVSDAVRRSRAGLQDPN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCC
RPLGSFLFLGPTGVGKTELARALAEFLFDDEAAMVRIDMSEYMERHAVARLIGAPPGYVG
CCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCC
YEEGGQLTEAVRRRPYSVVLFDEIEKAHPDVFNTLLQLLDDGRLTDGQGRLVDFTNTVVI
CCCCCHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEE
MTSNIGSNRIQSLVDDEEAMREAVLEELHDELRPEFLNRIDDVIIFKPLTQAEIKHIVDI
EECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHHHH
QVDRLSKRLSERKLKLVLNEAARQHLAQVGYDPVFGARPLKRAIQSELLNPLALEVLKGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
FPGGTTVNVDVKNGKLSFD
CCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]