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The map label for this gene is pyrH [H]

Identifier: 159901470

GI number: 159901470

Start: 6294229

End: 6294975

Strand: Reverse

Name: pyrH [H]

Synonym: Haur_4959

Alternate gene names: 159901470

Gene position: 6294975-6294229 (Counterclockwise)

Preceding gene: 159901471

Following gene: 159901469

Centisome position: 99.19

GC content: 51.14

Gene sequence:

>747_bases
ATGCAACCACGCTACAAACGGGTTTTGCTCAAGCTCAGTGGCGAAGCATTGGCTGGCGATGGTAAAACCAATATTTCGCC
TGACGTGTTAAACTATATGTCAGCCGAGATTAAGCCATTGTTGGCGCATGGGGTGCAAGTGGCAATTGTGCTTGGCGGCG
GCAATATCTGGCGTGGTGGCCCAGCAATCAAAGCTGGCATGGAACCACCCCAAGCACATTATATGGGCATGCTGGCAACA
ATTATCAATGCCTTAGCCTTGCAAGATGCGCTTGAGCGTAACGGCATGCAAACCCGTGCCATGACCGCGATTAAAATGGA
TGAGGTGGCAGAATCGTACATTCGACGGCGAGCGGTGCGCCATATGGAAAAAGGCCGAGTGGTTATTTTGGCCGCTGGCA
CTGGTAATCCTTATTTCACCACCGATTCGGGCGCAGCTTTACGCGCTGCCGAACTCGATGCCGATGTTATTCTGATGGCC
AAAAACCGCGTTGATGGGGTGTATAGCGCTGACCCACGCACCGACCCCAAAGCAACCAAATTTGACCATATCACCTATCT
TGATGCCCTAACCCGTGGCTTAACGATTATGGACAGTACGGCGCTGACCTTTTGCATGGATAATAATCTTCCAATCATTG
TATTTAGCCTCGATACCCCAGGCAATTTGGAACGAATTGTGCTAGGTGAGCAGGTTGGTACCTTGATTAGCAAAGCCAAC
ACTGAAGCCCCCGCTACCGCTGGGTAG

Upstream 100 bases:

>100_bases
TTGTTCTCAATCCGCAGGCGACGGTTTTTTTCTGAAATCACGCAGGTGTTTGTTTCTTCCTTGCTTTTGATCTTTTGACT
TTCACTTGGAGGGTTCTGGT

Downstream 100 bases:

>100_bases
CATTAGCCAAATGACAAGGAGTTTTAGTATGACGGTTAAAGATGTTTTACGCGATGCCGAAAGCAAAATGAAAAAGAGCA
TCGATTCGTTGCGCCATACC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MQPRYKRVLLKLSGEALAGDGKTNISPDVLNYMSAEIKPLLAHGVQVAIVLGGGNIWRGGPAIKAGMEPPQAHYMGMLAT
IINALALQDALERNGMQTRAMTAIKMDEVAESYIRRRAVRHMEKGRVVILAAGTGNPYFTTDSGAALRAAELDADVILMA
KNRVDGVYSADPRTDPKATKFDHITYLDALTRGLTIMDSTALTFCMDNNLPIIVFSLDTPGNLERIVLGEQVGTLISKAN
TEAPATAG

Sequences:

>Translated_248_residues
MQPRYKRVLLKLSGEALAGDGKTNISPDVLNYMSAEIKPLLAHGVQVAIVLGGGNIWRGGPAIKAGMEPPQAHYMGMLAT
IINALALQDALERNGMQTRAMTAIKMDEVAESYIRRRAVRHMEKGRVVILAAGTGNPYFTTDSGAALRAAELDADVILMA
KNRVDGVYSADPRTDPKATKFDHITYLDALTRGLTIMDSTALTFCMDNNLPIIVFSLDTPGNLERIVLGEQVGTLISKAN
TEAPATAG
>Mature_248_residues
MQPRYKRVLLKLSGEALAGDGKTNISPDVLNYMSAEIKPLLAHGVQVAIVLGGGNIWRGGPAIKAGMEPPQAHYMGMLAT
IINALALQDALERNGMQTRAMTAIKMDEVAESYIRRRAVRHMEKGRVVILAAGTGNPYFTTDSGAALRAAELDADVILMA
KNRVDGVYSADPRTDPKATKFDHITYLDALTRGLTIMDSTALTFCMDNNLPIIVFSLDTPGNLERIVLGEQVGTLISKAN
TEAPATAG

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=237, Percent_Identity=49.3670886075949, Blast_Score=234, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26623; Mature: 26623

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPRYKRVLLKLSGEALAGDGKTNISPDVLNYMSAEIKPLLAHGVQVAIVLGGGNIWRGG
CCCHHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEECCC
PAIKAGMEPPQAHYMGMLATIINALALQDALERNGMQTRAMTAIKMDEVAESYIRRRAVR
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HMEKGRVVILAAGTGNPYFTTDSGAALRAAELDADVILMAKNRVDGVYSADPRTDPKATK
HHHCCCEEEEEECCCCCCEECCCCCEEEEECCCCCEEEEECCCCCCEECCCCCCCCCCCC
FDHITYLDALTRGLTIMDSTALTFCMDNNLPIIVFSLDTPGNLERIVLGEQVGTLISKAN
CHHHHHHHHHHHCCEEECCCEEEEEECCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHCC
TEAPATAG
CCCCCCCC
>Mature Secondary Structure
MQPRYKRVLLKLSGEALAGDGKTNISPDVLNYMSAEIKPLLAHGVQVAIVLGGGNIWRGG
CCCHHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEECCC
PAIKAGMEPPQAHYMGMLATIINALALQDALERNGMQTRAMTAIKMDEVAESYIRRRAVR
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HMEKGRVVILAAGTGNPYFTTDSGAALRAAELDADVILMAKNRVDGVYSADPRTDPKATK
HHHCCCEEEEEECCCCCCEECCCCCEEEEECCCCCEEEEECCCCCCEECCCCCCCCCCCC
FDHITYLDALTRGLTIMDSTALTFCMDNNLPIIVFSLDTPGNLERIVLGEQVGTLISKAN
CHHHHHHHHHHHCCEEECCCEEEEEECCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHCC
TEAPATAG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA