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The map label for this gene is tsf

Identifier: 159901471

GI number: 159901471

Start: 6295132

End: 6295728

Strand: Reverse

Name: tsf

Synonym: Haur_4960

Alternate gene names: 159901471

Gene position: 6295728-6295132 (Counterclockwise)

Preceding gene: 159901472

Following gene: 159901470

Centisome position: 99.2

GC content: 49.75

Gene sequence:

>597_bases
GTGAGTATCTCGATGGATCAAGTCAAGGAACTCCGCGAACGCACCGGCGCTGGCATCCTCGACTGCAAGAAGGCGCTGAC
GGATACCAGTGGCGATGTTGACGCTGCAATCAAGATTTTGCGCGAAAAAGGCTTGGCTGCCGCCGCCAAGAAATCATCAC
GCGATGCCAGCGATGGCCGGATCGAAGTTTATGTCCACCCAGGCAATAAAGTTGTTGCGATTGTGGAAGTAAACTGCGAA
ACCGACTTCGTGGCCAAAACCGACGATTTCAAGAAATTGGCCTATGATTTGGCCTTGCACGTTGCTGCAACCAACCCATC
ATATGTCAATCGCGAAGAAGTGCCAGCAGCCGAAGTCGAACGCGAACGCGAAATCTTGCGCCAACAAAATGTCGATAGTG
GCAAGCCAGCCAATATCGTCGAAAAAATTGTTGAAGGTCGCATCGAGAAATTCTATGGCGAAATCGTCTTGCTCGAACAA
GAATTCGTCAAAGATCCTAGCGTCAAGATCAAAGATTTGGTCCAAGAAGCGATTGCTAAATTGGGCGAAAACATCGTTGT
GCGCCGCTTTAGCCGCTTTGAAGTTGGCAGCAACTAA

Upstream 100 bases:

>100_bases
TTCCGGCCTGCGCTCGCGAATGCCGTCCTAGTATCGATAGACACCCAGACCCCGGACGAGCAACAATGCTCGTCCGTTTT
TACAACAAGGAGAATACCCT

Downstream 100 bases:

>100_bases
ACAGTGCGACGATTGGCGCAACCCAATCTATTCGCTCTTCAACCGTCGTTTGTGGATTGTTCTCAATCCGCAGGCGACGG
TTTTTTTCTGAAATCACGCA

Product: translation elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSISMDQVKELRERTGAGILDCKKALTDTSGDVDAAIKILREKGLAAAAKKSSRDASDGRIEVYVHPGNKVVAIVEVNCE
TDFVAKTDDFKKLAYDLALHVAATNPSYVNREEVPAAEVEREREILRQQNVDSGKPANIVEKIVEGRIEKFYGEIVLLEQ
EFVKDPSVKIKDLVQEAIAKLGENIVVRRFSRFEVGSN

Sequences:

>Translated_198_residues
MSISMDQVKELRERTGAGILDCKKALTDTSGDVDAAIKILREKGLAAAAKKSSRDASDGRIEVYVHPGNKVVAIVEVNCE
TDFVAKTDDFKKLAYDLALHVAATNPSYVNREEVPAAEVEREREILRQQNVDSGKPANIVEKIVEGRIEKFYGEIVLLEQ
EFVKDPSVKIKDLVQEAIAKLGENIVVRRFSRFEVGSN
>Mature_197_residues
SISMDQVKELRERTGAGILDCKKALTDTSGDVDAAIKILREKGLAAAAKKSSRDASDGRIEVYVHPGNKVVAIVEVNCET
DFVAKTDDFKKLAYDLALHVAATNPSYVNREEVPAAEVEREREILRQQNVDSGKPANIVEKIVEGRIEKFYGEIVLLEQE
FVKDPSVKIKDLVQEAIAKLGENIVVRRFSRFEVGSN

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084500, Length=206, Percent_Identity=32.0388349514563, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786366, Length=121, Percent_Identity=47.1074380165289, Blast_Score=91, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17561440, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_HERA2 (A9B457)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547718.1
- ProteinModelPortal:   A9B457
- SMR:   A9B457
- GeneID:   5736796
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4960
- HOGENOM:   HBG713289
- OMA:   NVEYVSI
- BioCyc:   HAUR316274:HAUR_4960-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 21945; Mature: 21814

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISMDQVKELRERTGAGILDCKKALTDTSGDVDAAIKILREKGLAAAAKKSSRDASDGR
CCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCE
IEVYVHPGNKVVAIVEVNCETDFVAKTDDFKKLAYDLALHVAATNPSYVNREEVPAAEVE
EEEEEECCCEEEEEEEECCCCCCEECCHHHHHHHHHHHHEEEECCCCCCCHHCCCHHHHH
REREILRQQNVDSGKPANIVEKIVEGRIEKFYGEIVLLEQEFVKDPSVKIKDLVQEAIAK
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHCCCCCCHHHHHHHHHHHH
LGENIVVRRFSRFEVGSN
HCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SISMDQVKELRERTGAGILDCKKALTDTSGDVDAAIKILREKGLAAAAKKSSRDASDGR
CCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCE
IEVYVHPGNKVVAIVEVNCETDFVAKTDDFKKLAYDLALHVAATNPSYVNREEVPAAEVE
EEEEEECCCEEEEEEEECCCCCCEECCHHHHHHHHHHHHEEEECCCCCCCHHCCCHHHHH
REREILRQQNVDSGKPANIVEKIVEGRIEKFYGEIVLLEQEFVKDPSVKIKDLVQEAIAK
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHCCCCCCHHHHHHHHHHHH
LGENIVVRRFSRFEVGSN
HCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA