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The map label for this gene is frr [H]

Identifier: 159901469

GI number: 159901469

Start: 6293640

End: 6294218

Strand: Reverse

Name: frr [H]

Synonym: Haur_4958

Alternate gene names: 159901469

Gene position: 6294218-6293640 (Counterclockwise)

Preceding gene: 159901470

Following gene: 159901468

Centisome position: 99.17

GC content: 50.26

Gene sequence:

>579_bases
ATGACAAGGAGTTTTAGTATGACGGTTAAAGATGTTTTACGCGATGCCGAAAGCAAAATGAAAAAGAGCATCGATTCGTT
GCGCCATACCCTTGGTGCTGTGCGCACTGGCCGCGCCTCTCCCGCCTTGGTCGAAGATTTGAAGGTTGAATATTATGGCT
CTGAAATGCCGCTCAACCAGTTGGCCAACATCGCTACCCCTGAATCACGTATGATCACGATTCAACCCTACGATCAAGGG
GCAATCAAGGCGATTGAAAAGGCCATCCAAAATTCCGAGTTGGGAATCAACCCGAGCAACGATGGCCGCGTCATTCGCTT
GGCGATTCCCCAATTGACCCAAGAACGTCGTAAGGAGTTGGTCAAGCAGGTCAAGGCCAAAGTTGAAGATGGCAAAGTGG
CGATTCGCAATGTGCGCCGCGAAGCCCAAGATGCCATTCGCAAATTGCAACAAGATAAGGCCATCTCGGAAGATGACGAG
CGTCGTGGCCAGGAAGAGTTGCAAAAATTGACCGACCGCTTCCAAAAGGAAGTTGAAACGATCGGCACAACCAAAGAAGC
CGAGGTCATGGAAGTCTAG

Upstream 100 bases:

>100_bases
CCAGGCAATTTGGAACGAATTGTGCTAGGTGAGCAGGTTGGTACCTTGATTAGCAAAGCCAACACTGAAGCCCCCGCTAC
CGCTGGGTAGCATTAGCCAA

Downstream 100 bases:

>100_bases
GACTTGTGGCTGTTGGTAAATTAAGCGTTGGCCTACCACCAGTAGGCCAACGCTTAATTCAACTCAACCGACTGCACAAG
CCCAAAAATCCCCCATGAGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTRSFSMTVKDVLRDAESKMKKSIDSLRHTLGAVRTGRASPALVEDLKVEYYGSEMPLNQLANIATPESRMITIQPYDQG
AIKAIEKAIQNSELGINPSNDGRVIRLAIPQLTQERRKELVKQVKAKVEDGKVAIRNVRREAQDAIRKLQQDKAISEDDE
RRGQEELQKLTDRFQKEVETIGTTKEAEVMEV

Sequences:

>Translated_192_residues
MTRSFSMTVKDVLRDAESKMKKSIDSLRHTLGAVRTGRASPALVEDLKVEYYGSEMPLNQLANIATPESRMITIQPYDQG
AIKAIEKAIQNSELGINPSNDGRVIRLAIPQLTQERRKELVKQVKAKVEDGKVAIRNVRREAQDAIRKLQQDKAISEDDE
RRGQEELQKLTDRFQKEVETIGTTKEAEVMEV
>Mature_191_residues
TRSFSMTVKDVLRDAESKMKKSIDSLRHTLGAVRTGRASPALVEDLKVEYYGSEMPLNQLANIATPESRMITIQPYDQGA
IKAIEKAIQNSELGINPSNDGRVIRLAIPQLTQERRKELVKQVKAKVEDGKVAIRNVRREAQDAIRKLQQDKAISEDDER
RGQEELQKLTDRFQKEVETIGTTKEAEVMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=169, Percent_Identity=28.9940828402367, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=45.9016393442623, Blast_Score=176, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21734; Mature: 21603

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSFSMTVKDVLRDAESKMKKSIDSLRHTLGAVRTGRASPALVEDLKVEYYGSEMPLNQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHH
LANIATPESRMITIQPYDQGAIKAIEKAIQNSELGINPSNDGRVIRLAIPQLTQERRKEL
HHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
VKQVKAKVEDGKVAIRNVRREAQDAIRKLQQDKAISEDDERRGQEELQKLTDRFQKEVET
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHH
IGTTKEAEVMEV
HCCCCCHHHHCC
>Mature Secondary Structure 
TRSFSMTVKDVLRDAESKMKKSIDSLRHTLGAVRTGRASPALVEDLKVEYYGSEMPLNQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHH
LANIATPESRMITIQPYDQGAIKAIEKAIQNSELGINPSNDGRVIRLAIPQLTQERRKEL
HHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
VKQVKAKVEDGKVAIRNVRREAQDAIRKLQQDKAISEDDERRGQEELQKLTDRFQKEVET
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHH
IGTTKEAEVMEV
HCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA