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The map label for this gene is argE [H]

Identifier: 159901460

GI number: 159901460

Start: 6276438

End: 6277535

Strand: Direct

Name: argE [H]

Synonym: Haur_4949

Alternate gene names: 159901460

Gene position: 6276438-6277535 (Clockwise)

Preceding gene: 159901459

Following gene: 159901473

Centisome position: 98.89

GC content: 51.91

Gene sequence:

>1098_bases
GTGTCAATCCGTACAAGTTTGGTTGATCTGACCACGCGCTTGGTGGCGATTCCCAGTGTTTCCGCCGAAAAACGCGATTT
GCAGCCAGTGATCGATCTGGTGGTGGCTGAATTAGCCGATTATCCAGCGGCGTTGTTGCATCATCGCGATGCTAATGGCT
ACCCAATGTTGGTGGTCAATTTCAACCAAGAACTGCGCAGCGATCTTATTTTGAATGCCCATTTGGATGTTGTGCCAGCC
CGCCCTGAGCAATGGCACGCCTTCGAGCATGATGGCAAATTGTATGGTCGTGGCACGCAAGATATGAAGGGATCGGCGGC
GGTCTACATTGAAATTATTAAAGAAATTGCCCAATTGCCTGCTGAGCAACGCCCTAACGTAAGCTTTCAATTTGTGACCG
ATGAGGAAATTGGCGGAGCAAATGGCACAGCCTTATTGCGTGATGAAGGCTGGCAGGCTAATTTATTTATTGCTGGCGAG
CCGACCAACCTGAATATTTGTCATGGAGCCAAGGGCATTTTATGGCTGGCAGTTGAGCAACCAGGCGTGCCAGCCCATGG
TTCGCGGCCTTGGGAAGGCGTGAATCCGATTGAGCGTTTGGCAAGTGGCCTTGGGCGTTTGTACGAATATTATCCAACGC
CTGCGCAAGAAATTTGGCGCACTACGGTTACGCCTTCGATTATCAAAGGCGGCGATGCTGGCAATCGGATTCCAGCCAAT
GCCCAACTGAATCTTGATATTCGCTGGACACCCGAAGAAGGTGCTGATGCGGTGATTGATAACGTGAAGCAAGCCTTTGC
AACGAGCAGCGAACCCAATCCCAATGTGCAGATTTTGCATCGTGGCACGGCCCTAAATACGCCAGCCGAGGAGCCAAACT
TACAACGCATTGTTGATGCACAACAATCCAGCCTTGGTCGCCAAGCCCAACTCTTCCGCGAGCATTTTGGCTCCGATGCC
CGCTTCTACAGCGATGCCGGAATTCCAGCGGTCTGTTGGGGGCCAGAAGGTGCAGGCTTGCATACCGACGACGAGTGGGT
CAGCATCGATGGCTTGGTCGATTATTATCAGGCGGTCAAAACCTTGTTGGGTATGTAG

Upstream 100 bases:

>100_bases
TCGCTAAATTAACGAATAATCAAGATTCAACCCTTAGCCCTAGCGTGTTGCGCTGGGGCTTTTGCTACAATACAGTCAGG
TTTATCGAAAGGGGTTCTGT

Downstream 100 bases:

>100_bases
GTGATCCACGAAGGCCGAGGGATCAGGGATCAGGGGTTAGGAATCAGCTTGGCAATGCGAGGCTGAATCCTGATCCCTGA
TCCCTGATAAACTCTGTGCC

Product: peptidase M20

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSIRTSLVDLTTRLVAIPSVSAEKRDLQPVIDLVVAELADYPAALLHHRDANGYPMLVVNFNQELRSDLILNAHLDVVPA
RPEQWHAFEHDGKLYGRGTQDMKGSAAVYIEIIKEIAQLPAEQRPNVSFQFVTDEEIGGANGTALLRDEGWQANLFIAGE
PTNLNICHGAKGILWLAVEQPGVPAHGSRPWEGVNPIERLASGLGRLYEYYPTPAQEIWRTTVTPSIIKGGDAGNRIPAN
AQLNLDIRWTPEEGADAVIDNVKQAFATSSEPNPNVQILHRGTALNTPAEEPNLQRIVDAQQSSLGRQAQLFREHFGSDA
RFYSDAGIPAVCWGPEGAGLHTDDEWVSIDGLVDYYQAVKTLLGM

Sequences:

>Translated_365_residues
MSIRTSLVDLTTRLVAIPSVSAEKRDLQPVIDLVVAELADYPAALLHHRDANGYPMLVVNFNQELRSDLILNAHLDVVPA
RPEQWHAFEHDGKLYGRGTQDMKGSAAVYIEIIKEIAQLPAEQRPNVSFQFVTDEEIGGANGTALLRDEGWQANLFIAGE
PTNLNICHGAKGILWLAVEQPGVPAHGSRPWEGVNPIERLASGLGRLYEYYPTPAQEIWRTTVTPSIIKGGDAGNRIPAN
AQLNLDIRWTPEEGADAVIDNVKQAFATSSEPNPNVQILHRGTALNTPAEEPNLQRIVDAQQSSLGRQAQLFREHFGSDA
RFYSDAGIPAVCWGPEGAGLHTDDEWVSIDGLVDYYQAVKTLLGM
>Mature_364_residues
SIRTSLVDLTTRLVAIPSVSAEKRDLQPVIDLVVAELADYPAALLHHRDANGYPMLVVNFNQELRSDLILNAHLDVVPAR
PEQWHAFEHDGKLYGRGTQDMKGSAAVYIEIIKEIAQLPAEQRPNVSFQFVTDEEIGGANGTALLRDEGWQANLFIAGEP
TNLNICHGAKGILWLAVEQPGVPAHGSRPWEGVNPIERLASGLGRLYEYYPTPAQEIWRTTVTPSIIKGGDAGNRIPANA
QLNLDIRWTPEEGADAVIDNVKQAFATSSEPNPNVQILHRGTALNTPAEEPNLQRIVDAQQSSLGRQAQLFREHFGSDAR
FYSDAGIPAVCWGPEGAGLHTDDEWVSIDGLVDYYQAVKTLLGM

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=228, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790395, Length=359, Percent_Identity=27.0194986072423, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788816, Length=390, Percent_Identity=25.1282051282051, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982082, Length=325, Percent_Identity=27.0769230769231, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71982085, Length=339, Percent_Identity=26.8436578171091, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538640, Length=294, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649206, Length=335, Percent_Identity=24.4776119402985, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356353, Length=373, Percent_Identity=23.0563002680965, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 40019; Mature: 39888

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRTSLVDLTTRLVAIPSVSAEKRDLQPVIDLVVAELADYPAALLHHRDANGYPMLVVN
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEE
FNQELRSDLILNAHLDVVPARPEQWHAFEHDGKLYGRGTQDMKGSAAVYIEIIKEIAQLP
CCHHHHHCEEEECCEEEECCCCHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
AEQRPNVSFQFVTDEEIGGANGTALLRDEGWQANLFIAGEPTNLNICHGAKGILWLAVEQ
CCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCEEEEECCCCEEEEEEEC
PGVPAHGSRPWEGVNPIERLASGLGRLYEYYPTPAQEIWRTTVTPSIIKGGDAGNRIPAN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHEECCCCCCCCCCC
AQLNLDIRWTPEEGADAVIDNVKQAFATSSEPNPNVQILHRGTALNTPAEEPNLQRIVDA
CEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
QQSSLGRQAQLFREHFGSDARFYSDAGIPAVCWGPEGAGLHTDDEWVSIDGLVDYYQAVK
HHHHCCHHHHHHHHHCCCCCEEECCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHH
TLLGM
HHHCC
>Mature Secondary Structure 
SIRTSLVDLTTRLVAIPSVSAEKRDLQPVIDLVVAELADYPAALLHHRDANGYPMLVVN
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEE
FNQELRSDLILNAHLDVVPARPEQWHAFEHDGKLYGRGTQDMKGSAAVYIEIIKEIAQLP
CCHHHHHCEEEECCEEEECCCCHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
AEQRPNVSFQFVTDEEIGGANGTALLRDEGWQANLFIAGEPTNLNICHGAKGILWLAVEQ
CCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEECCCCCEEEEECCCCEEEEEEEC
PGVPAHGSRPWEGVNPIERLASGLGRLYEYYPTPAQEIWRTTVTPSIIKGGDAGNRIPAN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHEECCCCCCCCCCC
AQLNLDIRWTPEEGADAVIDNVKQAFATSSEPNPNVQILHRGTALNTPAEEPNLQRIVDA
CEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
QQSSLGRQAQLFREHFGSDARFYSDAGIPAVCWGPEGAGLHTDDEWVSIDGLVDYYQAVK
HHHHCCHHHHHHHHHCCCCCEEECCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHH
TLLGM
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA