Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 159901459

GI number: 159901459

Start: 6275220

End: 6276344

Strand: Direct

Name: degP [H]

Synonym: Haur_4948

Alternate gene names: 159901459

Gene position: 6275220-6276344 (Clockwise)

Preceding gene: 159901457

Following gene: 159901460

Centisome position: 98.88

GC content: 51.56

Gene sequence:

>1125_bases
ATGCAGCTTCGTGATCGTTTGGGTTGGATGCTGAGTGGTCTATTGCTGGGCATGCTATTGATGGTTAGTTGCGATGTGGT
CAATCAAGCTTCTACGGCTCAGCCAAGTGTGGTTGATGCTGCCGCTGTGCCTTCAACTGGACCATTGGCCACCGCTGCTG
CCCAAATGCCTGTTAATCAGGCTGGCGTTGATGCCTATAGCAATGTGATTCGGGCCGTTTACAATCGCGGTAATCCTTCG
GTGGTGCGAATTGACGTGCAAAGTGAGCAAGGCGAATCGCTCGGAACAGGTTTTGTGATCGATAAACAGGGCCATATTGT
CACCAACAATCACGTTGTTGGCAGCAGCCGCAGCGTGTTAGTCAATTTTATCGATGGTGATGCAGGGATCGCCGATGTGA
TTGGCGTTGATAGCGATTCAGATTTGGCAGTAATTAAAATGCGTAATCCTGATCCTGCTATTCTGATTCCTGTTGAGTTT
GGCGATTCGGCGGCGGTGCAAGTTGGCGATGTGGTGGTAGCGATTGGGAATCCCTATGGTGAAAATCGTACCGCGACTGC
GGGGATTATTAGTGCGATTCGTGGAGCCAAGAATGAGGGTGGCGGCAGTACCTTTTCAATTCCTGGGGTGTTGCAAACCG
ATGCGGCGATTAACCCAGGCAATTCGGGCGGGCCATTGTTCAACAGCCAAGGCCAAGTAATTGGGGTCAATACCTTTATT
CTCGACCCATCGGGGCGGGGCGCGAATATTGGCTTGGGTTTTGCAGTGCCGATTAATTTGGTTAAGCTGGTGGCCCCAGC
GATTATTCGCGATGGCAGCTATACGCATCCATTCTTTGGCGCGGCGGTAAGTAGCGTTGATAGCTATTTTGCTGAAGTTA
ATAATTTACCAAGCAAAGGCATTATTATTACCCAACTCTACAATGGCCCTGCTGCCGAGGCTGGCTTGCAAGTGGGCGAT
GTGATTGTCTCGGTTAATGGTGAGCCAATGCTTGAAGCTGGCGATCTGATCACGCTCTTAGAATTAACCACCCAACCAGG
TGATCGGATGACGGTTACGGTGGCCGAGGGCAATGGCCGCACCCGTGATGTGCAAGTGCTGGTCGGGGCACGTCCAGGTC
GCTAA

Upstream 100 bases:

>100_bases
ATGGATTAGGACAATTATAGCCAACTTTGACCGTAGGAGGATGGCGCTGCTTTTGCTATACTCGCTCTAGATTCCCGATG
TTTTGTTATTTGGAGGTTGT

Downstream 100 bases:

>100_bases
ATTAACGAATAATCAAGATTCAACCCTTAGCCCTAGCGTGTTGCGCTGGGGCTTTTGCTACAATACAGTCAGGTTTATCG
AAAGGGGTTCTGTGTGTCAA

Product: peptidase S1 and S6 chymotrypsin/Hap

Products: NA

Alternate protein names: Antigen htrA [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MQLRDRLGWMLSGLLLGMLLMVSCDVVNQASTAQPSVVDAAAVPSTGPLATAAAQMPVNQAGVDAYSNVIRAVYNRGNPS
VVRIDVQSEQGESLGTGFVIDKQGHIVTNNHVVGSSRSVLVNFIDGDAGIADVIGVDSDSDLAVIKMRNPDPAILIPVEF
GDSAAVQVGDVVVAIGNPYGENRTATAGIISAIRGAKNEGGGSTFSIPGVLQTDAAINPGNSGGPLFNSQGQVIGVNTFI
LDPSGRGANIGLGFAVPINLVKLVAPAIIRDGSYTHPFFGAAVSSVDSYFAEVNNLPSKGIIITQLYNGPAAEAGLQVGD
VIVSVNGEPMLEAGDLITLLELTTQPGDRMTVTVAEGNGRTRDVQVLVGARPGR

Sequences:

>Translated_374_residues
MQLRDRLGWMLSGLLLGMLLMVSCDVVNQASTAQPSVVDAAAVPSTGPLATAAAQMPVNQAGVDAYSNVIRAVYNRGNPS
VVRIDVQSEQGESLGTGFVIDKQGHIVTNNHVVGSSRSVLVNFIDGDAGIADVIGVDSDSDLAVIKMRNPDPAILIPVEF
GDSAAVQVGDVVVAIGNPYGENRTATAGIISAIRGAKNEGGGSTFSIPGVLQTDAAINPGNSGGPLFNSQGQVIGVNTFI
LDPSGRGANIGLGFAVPINLVKLVAPAIIRDGSYTHPFFGAAVSSVDSYFAEVNNLPSKGIIITQLYNGPAAEAGLQVGD
VIVSVNGEPMLEAGDLITLLELTTQPGDRMTVTVAEGNGRTRDVQVLVGARPGR
>Mature_374_residues
MQLRDRLGWMLSGLLLGMLLMVSCDVVNQASTAQPSVVDAAAVPSTGPLATAAAQMPVNQAGVDAYSNVIRAVYNRGNPS
VVRIDVQSEQGESLGTGFVIDKQGHIVTNNHVVGSSRSVLVNFIDGDAGIADVIGVDSDSDLAVIKMRNPDPAILIPVEF
GDSAAVQVGDVVVAIGNPYGENRTATAGIISAIRGAKNEGGGSTFSIPGVLQTDAAINPGNSGGPLFNSQGQVIGVNTFI
LDPSGRGANIGLGFAVPINLVKLVAPAIIRDGSYTHPFFGAAVSSVDSYFAEVNNLPSKGIIITQLYNGPAAEAGLQVGD
VIVSVNGEPMLEAGDLITLLELTTQPGDRMTVTVAEGNGRTRDVQVLVGARPGR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=337, Percent_Identity=32.0474777448071, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4506141, Length=313, Percent_Identity=30.6709265175719, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI24308541, Length=320, Percent_Identity=31.5625, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI7019477, Length=287, Percent_Identity=34.8432055749129, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1789629, Length=365, Percent_Identity=33.1506849315069, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1786356, Length=242, Percent_Identity=41.7355371900826, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789630, Length=334, Percent_Identity=35.9281437125749, Blast_Score=149, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24646839, Length=268, Percent_Identity=32.4626865671642, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 38421; Mature: 38421

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRDRLGWMLSGLLLGMLLMVSCDVVNQASTAQPSVVDAAAVPSTGPLATAAAQMPVNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHCCCCCCCHHHHHHHCCCCC
AGVDAYSNVIRAVYNRGNPSVVRIDVQSEQGESLGTGFVIDKQGHIVTNNHVVGSSRSVL
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEECCEEECCCCEEE
VNFIDGDAGIADVIGVDSDSDLAVIKMRNPDPAILIPVEFGDSAAVQVGDVVVAIGNPYG
EEEECCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCEEEECEEEEEECCCCC
ENRTATAGIISAIRGAKNEGGGSTFSIPGVLQTDAAINPGNSGGPLFNSQGQVIGVNTFI
CCCCHHHHHHHHHHCCCCCCCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEE
LDPSGRGANIGLGFAVPINLVKLVAPAIIRDGSYTHPFFGAAVSSVDSYFAEVNNLPSKG
ECCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
IIITQLYNGPAAEAGLQVGDVIVSVNGEPMLEAGDLITLLELTTQPGDRMTVTVAEGNGR
EEEEEECCCCCHHCCCEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCC
TRDVQVLVGARPGR
CEEEEEEEECCCCC
>Mature Secondary Structure
MQLRDRLGWMLSGLLLGMLLMVSCDVVNQASTAQPSVVDAAAVPSTGPLATAAAQMPVNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHCCCCCCCHHHHHHHCCCCC
AGVDAYSNVIRAVYNRGNPSVVRIDVQSEQGESLGTGFVIDKQGHIVTNNHVVGSSRSVL
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEECCEEECCCCEEE
VNFIDGDAGIADVIGVDSDSDLAVIKMRNPDPAILIPVEFGDSAAVQVGDVVVAIGNPYG
EEEECCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCEEEECEEEEEECCCCC
ENRTATAGIISAIRGAKNEGGGSTFSIPGVLQTDAAINPGNSGGPLFNSQGQVIGVNTFI
CCCCHHHHHHHHHHCCCCCCCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEE
LDPSGRGANIGLGFAVPINLVKLVAPAIIRDGSYTHPFFGAAVSSVDSYFAEVNNLPSKG
ECCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
IIITQLYNGPAAEAGLQVGDVIVSVNGEPMLEAGDLITLLELTTQPGDRMTVTVAEGNGR
EEEEEECCCCCHHCCCEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCC
TRDVQVLVGARPGR
CEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8027347 [H]