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The map label for this gene is mtnP [H]

Identifier: 159901420

GI number: 159901420

Start: 6246289

End: 6247149

Strand: Direct

Name: mtnP [H]

Synonym: Haur_4909

Alternate gene names: 159901420

Gene position: 6246289-6247149 (Clockwise)

Preceding gene: 159901419

Following gene: 159901423

Centisome position: 98.42

GC content: 53.31

Gene sequence:

>861_bases
ATGGAACCAATTAGCATTGGAATTATTGGCGGTAGCGGGCTATATGCAATGGAAGCCCTGACCGACCGCAGCGAAATACA
ACTTACAACCCCATTTGGCGATCCCAGCGATGCTGTGATTGTTGGCAATTTGGCTGGGCAACGGGTGGCATTTTTGCCGC
GCCATGGCCGTGGGCATCGCTTTACCCCCTCAGAAGTACCCTATCGTGCCAATATTCATGCGCTCAAACAATTGGGAGTA
CGTTTTATCTTGGGTGTCAGTGCGGTTGGCAGCTTGCGCGAAGAGTTGGTACCAGGCCATTTGGTTATTCCCGATCAAGC
GATTGATCGCACCAAGGGCGTGCGGCCTGCGACCTTCTTTGGCGAGGGCGTGGTAGCGCATGTGGCGTTTGGCGAGCCAG
TTTGCCCGTATTTGAGTGCTTTGGTGAGCCAAGCGGCGCATTCAGCCAGCAACACAACCGTGCATGATGGTGGAACCTAC
TGCTGCATGGAAGGGCCGCAGTTTTCGACGAAGGCTGAGTCGGAGCTTTATCGCAGTTGGGGTTGCTCGATAATTGGCAT
GACCTTGCTGCCCGAGGCCAAACTTGCGCGAGAGGCCGAAATTGCCTATGCCAATCTTTCATTGGTTACCGATTACGATT
GCTGGCATCCCGATCATGATAATGTAACGGCAGCGATGGTGGTTGAAACAATCAATCGTAATGTCACAGCGGCTCAATCG
ACAATTGCCGCATTAATTCCCTTGATTGATCCGACGGCAGTTTATCCAGCGCATTCAGCATTGGCCCATGCCGTGATGAC
TGCTCCAGAAGCGATTCCTGCGGCAGCGCGTGAACGTTTGGCCTTGCTTTATCGTGGCTAG

Upstream 100 bases:

>100_bases
TAAGTTTTTTAATCAATAACTACTTGCCCTATCACGCTGGTGATGGGGCATTTGGCGTGTGCTCTGCTATACTAGGCCAA
TATCAACAGGAGGATCAACA

Downstream 100 bases:

>100_bases
GGTGGTAAACGTGATTAAACAAAAACCCAGCACCACGTGGTGCTGGGTTTTTGTTGAAGTCCGCGAGAGAGACTATTCCA
ACGCGTCTGAAACGGTTTGG

Product: methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEPISIGIIGGSGLYAMEALTDRSEIQLTTPFGDPSDAVIVGNLAGQRVAFLPRHGRGHRFTPSEVPYRANIHALKQLGV
RFILGVSAVGSLREELVPGHLVIPDQAIDRTKGVRPATFFGEGVVAHVAFGEPVCPYLSALVSQAAHSASNTTVHDGGTY
CCMEGPQFSTKAESELYRSWGCSIIGMTLLPEAKLAREAEIAYANLSLVTDYDCWHPDHDNVTAAMVVETINRNVTAAQS
TIAALIPLIDPTAVYPAHSALAHAVMTAPEAIPAAARERLALLYRG

Sequences:

>Translated_286_residues
MEPISIGIIGGSGLYAMEALTDRSEIQLTTPFGDPSDAVIVGNLAGQRVAFLPRHGRGHRFTPSEVPYRANIHALKQLGV
RFILGVSAVGSLREELVPGHLVIPDQAIDRTKGVRPATFFGEGVVAHVAFGEPVCPYLSALVSQAAHSASNTTVHDGGTY
CCMEGPQFSTKAESELYRSWGCSIIGMTLLPEAKLAREAEIAYANLSLVTDYDCWHPDHDNVTAAMVVETINRNVTAAQS
TIAALIPLIDPTAVYPAHSALAHAVMTAPEAIPAAARERLALLYRG
>Mature_286_residues
MEPISIGIIGGSGLYAMEALTDRSEIQLTTPFGDPSDAVIVGNLAGQRVAFLPRHGRGHRFTPSEVPYRANIHALKQLGV
RFILGVSAVGSLREELVPGHLVIPDQAIDRTKGVRPATFFGEGVVAHVAFGEPVCPYLSALVSQAAHSASNTTVHDGGTY
CCMEGPQFSTKAESELYRSWGCSIIGMTLLPEAKLAREAEIAYANLSLVTDYDCWHPDHDNVTAAMVVETINRNVTAAQS
TIAALIPLIDPTAVYPAHSALAHAVMTAPEAIPAAARERLALLYRG

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=255, Percent_Identity=42.7450980392157, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71980569, Length=284, Percent_Identity=39.0845070422535, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6323045, Length=302, Percent_Identity=37.0860927152318, Blast_Score=199, Evalue=5e-52,
Organism=Drosophila melanogaster, GI20130079, Length=245, Percent_Identity=40.8163265306122, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI221459247, Length=249, Percent_Identity=38.1526104417671, Blast_Score=170, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 30479; Mature: 30479

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPISIGIIGGSGLYAMEALTDRSEIQLTTPFGDPSDAVIVGNLAGQRVAFLPRHGRGHR
CCCEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCCC
FTPSEVPYRANIHALKQLGVRFILGVSAVGSLREELVPGHLVIPDQAIDRTKGVRPATFF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCEEE
GEGVVAHVAFGEPVCPYLSALVSQAAHSASNTTVHDGGTYCCMEGPQFSTKAESELYRSW
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCCHHHHHHHHHH
GCSIIGMTLLPEAKLAREAEIAYANLSLVTDYDCWHPDHDNVTAAMVVETINRNVTAAQS
CCEEEEEECCCCHHHHHHHHEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHH
TIAALIPLIDPTAVYPAHSALAHAVMTAPEAIPAAARERLALLYRG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHEEEEECC
>Mature Secondary Structure
MEPISIGIIGGSGLYAMEALTDRSEIQLTTPFGDPSDAVIVGNLAGQRVAFLPRHGRGHR
CCCEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCCC
FTPSEVPYRANIHALKQLGVRFILGVSAVGSLREELVPGHLVIPDQAIDRTKGVRPATFF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCEEE
GEGVVAHVAFGEPVCPYLSALVSQAAHSASNTTVHDGGTYCCMEGPQFSTKAESELYRSW
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCCHHHHHHHHHH
GCSIIGMTLLPEAKLAREAEIAYANLSLVTDYDCWHPDHDNVTAAMVVETINRNVTAAQS
CCEEEEEECCCCHHHHHHHHEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHH
TIAALIPLIDPTAVYPAHSALAHAVMTAPEAIPAAARERLALLYRG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA