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The map label for this gene is divK [H]

Identifier: 159901419

GI number: 159901419

Start: 6245799

End: 6246191

Strand: Direct

Name: divK [H]

Synonym: Haur_4908

Alternate gene names: 159901419

Gene position: 6245799-6246191 (Clockwise)

Preceding gene: 159901418

Following gene: 159901420

Centisome position: 98.41

GC content: 46.06

Gene sequence:

>393_bases
ATGGGGATGATTTTAGTTGTTGATGATAATGGCGATAATCGTTTCTTGCTTCAACAGATGTTATCGTTGAATGGCTATAG
CGTGATTAGTGCTGTAAATGGGCAAGATGCCCTTGATAAAGTGCATAATACCACTCCCGATTTGGTGCTGATGGATATGG
CGATGCCAGTTAAAGATGGCTGGACGGCAACCGCCGAATTGAAGGCCCAAAGCCGCTATTCGCATATTCCGGTGATTGCG
GTAACTGGGCATACCACCTACAACGAGCTATCACGTGCCACGGCGGCTGGCTGTATCGATCATCTCGAAAAGCCGATCGA
CTATGAAGTGCTTGTGCGTAAAGTGGCCCAATATCTAAAAAAAAATGAAAAACAATTGGCGCTAGGCGCTTAA

Upstream 100 bases:

>100_bases
AATGTCCAGAGCAATCTGAAGCTACGCTGGTGATGGCAGCATCGCCACTGGTTAATTCGAGCGCTGTGGCCTGATACCCA
ACCAACTTAGGAGGATTCCC

Downstream 100 bases:

>100_bases
GTTTTTTAATCAATAACTACTTGCCCTATCACGCTGGTGATGGGGCATTTGGCGTGTGCTCTGCTATACTAGGCCAATAT
CAACAGGAGGATCAACAATG

Product: response regulator receiver protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MGMILVVDDNGDNRFLLQQMLSLNGYSVISAVNGQDALDKVHNTTPDLVLMDMAMPVKDGWTATAELKAQSRYSHIPVIA
VTGHTTYNELSRATAAGCIDHLEKPIDYEVLVRKVAQYLKKNEKQLALGA

Sequences:

>Translated_130_residues
MGMILVVDDNGDNRFLLQQMLSLNGYSVISAVNGQDALDKVHNTTPDLVLMDMAMPVKDGWTATAELKAQSRYSHIPVIA
VTGHTTYNELSRATAAGCIDHLEKPIDYEVLVRKVAQYLKKNEKQLALGA
>Mature_129_residues
GMILVVDDNGDNRFLLQQMLSLNGYSVISAVNGQDALDKVHNTTPDLVLMDMAMPVKDGWTATAELKAQSRYSHIPVIAV
TGHTTYNELSRATAAGCIDHLEKPIDYEVLVRKVAQYLKKNEKQLALGA

Specific function: Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localized at one pole of the cell. Colocalizes with pdhS (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=30.6451612903226, Blast_Score=69, Evalue=9e-14,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=35.1851851851852, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=122, Percent_Identity=34.4262295081967, Blast_Score=63, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 14287; Mature: 14155

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMILVVDDNGDNRFLLQQMLSLNGYSVISAVNGQDALDKVHNTTPDLVLMDMAMPVKDG
CCEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCCC
WTATAELKAQSRYSHIPVIAVTGHTTYNELSRATAAGCIDHLEKPIDYEVLVRKVAQYLK
CCEEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KNEKQLALGA
CCCCEEECCC
>Mature Secondary Structure 
GMILVVDDNGDNRFLLQQMLSLNGYSVISAVNGQDALDKVHNTTPDLVLMDMAMPVKDG
CEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCCCCC
WTATAELKAQSRYSHIPVIAVTGHTTYNELSRATAAGCIDHLEKPIDYEVLVRKVAQYLK
CCEEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KNEKQLALGA
CCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA