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The map label for this gene is mpg1 [H]

Identifier: 159901333

GI number: 159901333

Start: 6148920

End: 6149900

Strand: Direct

Name: mpg1 [H]

Synonym: Haur_4822

Alternate gene names: 159901333

Gene position: 6148920-6149900 (Clockwise)

Preceding gene: 159901332

Following gene: 159901334

Centisome position: 96.89

GC content: 53.41

Gene sequence:

>981_bases
ATGCGTGCAGTTATTTTAGTTGGCGGATTAGGCACACGCCTCCGCCCATTGACCAATCAACTCCCCAAGCCACTTGTGCC
AATTGCCGGCGAAGCCTTGATGAGCCGAACCTTGCGGCGTTTGTATAAGCAAGGGGTGCGTCATGTGATTTTGGCGGTGC
AATATTTGGCCGAACAATTTTTGGCGGCCTATGGCGATGGCGCGGCTTTTGGGCTAGATTTGCAGATTGTTCAAGAGCCA
GAAGCCCTAGGCACAGCTGGCGCAGTACGCTACGCCCTTGATCAAACCAATTTGCTTAAGGCTGGGCCGATTTTAGTGCT
GAATGGCGATGAACTGACTGATTTCGATGTGGCCCAACTCTGGCAAGCTCATGGCCAATTTGGCGGTGTGGCGACGATTG
CCGTGCGCCAAGTGGCCGATACCTCAGCCTTTGGGGTAGTTGCTAGCGATGCGAATCAACGAGTGTATGCCTTTCAAGAA
AAACCTGCGGCTGGCACGGCCTTGGCCAACACCATCAATAGCGGAGCCTATGTATTTGAGCCAGCGGCACTTGCCCAGAT
TCCAGCCCAAGGTTTTGCTATGCTCGAACGCGATCTCTTCCCCAGCTTGCTAGCGACTCAAGCCCTGATTTACGCCTATC
AACACAACGCCTACAGCCAAGATATTGGCACATTGGCAGGCTATTTAGCCGCGAATGAAGCGGTATTGTTGGGCCATTTG
CCGCATGAAACCGTGCATGGCATACAATATGCAGCAGGAGTGTGGGCTGCGGCTGATGCTCAAATCAGCCCTAGCGCCCA
ATTAATTGCCCCGATTATGCTTGGCAGTGGCTGTGTGGTGGGCGAGCATGCCCGACTTGAACGGGTGATCGCATGGGATC
GTGTTACAATTGAAGCCGCTGCAAACCTAAACAATGTCGCCATTGCCAATGATGTGCAGGTTGCCCACCATGCAACTGTC
GAAGGTCTCGCGCTTGGTTAA

Upstream 100 bases:

>100_bases
AGAAGGCCGCAATGATGTGTTATAAGTTATAATTGAAGGGCACGGCAGCAGGTGGTTAGCGATAACCAAACCACTGCCGT
GCTTTTATGAAAGCAGTTGT

Downstream 100 bases:

>100_bases
TATCATTCAATCCCATTCAAATTTTTGAACGCTATTTCGTTGTATTGACGAGCGATCGTCACCAATCTTCATTCATGGGA
AACCAATTTCAATCGCAAGC

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQFLAAYGDGAAFGLDLQIVQEP
EALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQLWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQE
KPAAGTALANTINSGAYVFEPAALAQIPAQGFAMLERDLFPSLLATQALIYAYQHNAYSQDIGTLAGYLAANEAVLLGHL
PHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHARLERVIAWDRVTIEAAANLNNVAIANDVQVAHHATV
EGLALG

Sequences:

>Translated_326_residues
MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQFLAAYGDGAAFGLDLQIVQEP
EALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQLWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQE
KPAAGTALANTINSGAYVFEPAALAQIPAQGFAMLERDLFPSLLATQALIYAYQHNAYSQDIGTLAGYLAANEAVLLGHL
PHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHARLERVIAWDRVTIEAAANLNNVAIANDVQVAHHATV
EGLALG
>Mature_326_residues
MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQFLAAYGDGAAFGLDLQIVQEP
EALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQLWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQE
KPAAGTALANTINSGAYVFEPAALAQIPAQGFAMLERDLFPSLLATQALIYAYQHNAYSQDIGTLAGYLAANEAVLLGHL
PHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHARLERVIAWDRVTIEAAANLNNVAIANDVQVAHHATV
EGLALG

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=330, Percent_Identity=30.9090909090909, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI11761619, Length=330, Percent_Identity=30.9090909090909, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI31881779, Length=361, Percent_Identity=27.9778393351801, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI45447090, Length=361, Percent_Identity=27.9778393351801, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1789837, Length=272, Percent_Identity=29.7794117647059, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790224, Length=184, Percent_Identity=30.9782608695652, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788351, Length=180, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=331, Percent_Identity=32.9305135951662, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17509979, Length=343, Percent_Identity=27.4052478134111, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17509981, Length=330, Percent_Identity=26.3636363636364, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320148, Length=336, Percent_Identity=27.9761904761905, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21355443, Length=321, Percent_Identity=33.9563862928349, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24644084, Length=321, Percent_Identity=33.9563862928349, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24653912, Length=190, Percent_Identity=30.5263157894737, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 34387; Mature: 34387

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQF
CEEEEEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAYGDGAAFGLDLQIVQEPEALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQL
HHHCCCCCEEEEEEEEEECCHHHCCHHHHHHHHCCCCCEECCCEEEECCCCCCCHHHHHH
WQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQEKPAAGTALANTINSGAYVFE
HHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHCCCCCEEEC
PAALAQIPAQGFAMLERDLFPSLLATQALIYAYQHNAYSQDIGTLAGYLAANEAVLLGHL
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECC
PHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHARLERVIAWDRVTIEAA
CCHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCCEECCHHHHHHHHHHCEEEEEEC
ANLNNVAIANDVQVAHHATVEGLALG
CCCCCEEEECCCCHHHHCCCCCEECC
>Mature Secondary Structure
MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQF
CEEEEEECCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAYGDGAAFGLDLQIVQEPEALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQL
HHHCCCCCEEEEEEEEEECCHHHCCHHHHHHHHCCCCCEECCCEEEECCCCCCCHHHHHH
WQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQEKPAAGTALANTINSGAYVFE
HHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHCCCCCEEEC
PAALAQIPAQGFAMLERDLFPSLLATQALIYAYQHNAYSQDIGTLAGYLAANEAVLLGHL
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECC
PHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHARLERVIAWDRVTIEAA
CCHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCCEECCHHHHHHHHHHCEEEEEEC
ANLNNVAIANDVQVAHHATVEGLALG
CCCCCEEEECCCCHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]