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The map label for this gene is fruK [H]

Identifier: 159901225

GI number: 159901225

Start: 6020885

End: 6021877

Strand: Direct

Name: fruK [H]

Synonym: Haur_4713

Alternate gene names: 159901225

Gene position: 6020885-6021877 (Clockwise)

Preceding gene: 159901224

Following gene: 159901226

Centisome position: 94.87

GC content: 53.27

Gene sequence:

>993_bases
ATGAGTATCGTTACATTAACGCTCAATCCCGCCATTGACCAAACGATTTTCATCAATAATTTTCAGCTGGAAACCGTCAA
TCGGGCCTACGATCTCAAGAGCCATGCTGGGGGCAAAGGCGTGAATGTCGCCTCGCTGTTGGCAGCCAACGGCCATAAGG
TGGTGGCAACTGGCTTTTTGGGCGACCAAAACACCGAATTATTCGATAAATTGTTTGCCGAAAAACAAATCGACGACCAA
TTTATTCGAATTCCAGGCCAGCCACGGGTTGGCATCAAAATTAGCGATCAACAAACCCAACGTACCACGGAAATTAATTT
GCCTGGCTTGACCCCAACCAACGAGCAATTGGATGCGATTCGCGCCACAATCAAACGCTTGGCTGCTGACGATAATCAAT
GGTTTATTTTGGCGGGCAACGTGCCGCCAGGTATTCCCAGCACAATTTATGGTCAGCTGATCGAAATTATTCGCGCCGCA
GGCAAGCAGGTTGTGTTGGATACCAGCGGCGAGGCCTTGCGCTACGGGTTGGCTGCCTCCCCAACCATCGCCAAGCCCAA
CCTTGCCGAACTTGAGCAATTTGTAGGCTACCCGCTGACCAGCGAACAAGCCGCCGCCAAAGCAGGCCGCGAACTGCTCA
GCCATGGCATCAAACTGGTGGTAATTTCGATGGGCGAACATGGCGCACTCTTTTTGGATAACGCCCAAAGTTTGGTGGCG
ATTCCGCCGAGTGTGGCGGTACAAAGCACGGTCGGCGCAGGCGATGCCATGGTTTCAGGCTTGGTTGCCGCCCAAACCCA
AGGGCTTGATCTTGCGGCGAGTGCCCGCTTGGCCACGGCCTTTGCTGCCGCCAAAATCACCCAGCTTGGCAGCAACTTAC
CCGCCGCCGAAATTGTCGAGCAGATTCGTGCTGATGTGGTGATTCGCCCATGCAATGCGCAACTTGATGTGTTGCAACGT
GGCGCGAATCAACTTAAAGGCGTTCCACTCTAA

Upstream 100 bases:

>100_bases
CCGAACTCAAAGCTGCCATTCGTCAACATAGCTTGGCCGATTTACAAGCACTCGCGCAACGTGCCTTGGCATGTCGCAGT
GCTGCCGAGGTACATCAATT

Downstream 100 bases:

>100_bases
TTTAAGAATGAATTATGAATTATGAGAGATGAAGGCAGAAGGCAAAATCAAAAGCCGAGTGATCAGGGGTCAGGGATCAG
ACGTTGAAACCGCGAAGCAC

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSIVTLTLNPAIDQTIFINNFQLETVNRAYDLKSHAGGKGVNVASLLAANGHKVVATGFLGDQNTELFDKLFAEKQIDDQ
FIRIPGQPRVGIKISDQQTQRTTEINLPGLTPTNEQLDAIRATIKRLAADDNQWFILAGNVPPGIPSTIYGQLIEIIRAA
GKQVVLDTSGEALRYGLAASPTIAKPNLAELEQFVGYPLTSEQAAAKAGRELLSHGIKLVVISMGEHGALFLDNAQSLVA
IPPSVAVQSTVGAGDAMVSGLVAAQTQGLDLAASARLATAFAAAKITQLGSNLPAAEIVEQIRADVVIRPCNAQLDVLQR
GANQLKGVPL

Sequences:

>Translated_330_residues
MSIVTLTLNPAIDQTIFINNFQLETVNRAYDLKSHAGGKGVNVASLLAANGHKVVATGFLGDQNTELFDKLFAEKQIDDQ
FIRIPGQPRVGIKISDQQTQRTTEINLPGLTPTNEQLDAIRATIKRLAADDNQWFILAGNVPPGIPSTIYGQLIEIIRAA
GKQVVLDTSGEALRYGLAASPTIAKPNLAELEQFVGYPLTSEQAAAKAGRELLSHGIKLVVISMGEHGALFLDNAQSLVA
IPPSVAVQSTVGAGDAMVSGLVAAQTQGLDLAASARLATAFAAAKITQLGSNLPAAEIVEQIRADVVIRPCNAQLDVLQR
GANQLKGVPL
>Mature_329_residues
SIVTLTLNPAIDQTIFINNFQLETVNRAYDLKSHAGGKGVNVASLLAANGHKVVATGFLGDQNTELFDKLFAEKQIDDQF
IRIPGQPRVGIKISDQQTQRTTEINLPGLTPTNEQLDAIRATIKRLAADDNQWFILAGNVPPGIPSTIYGQLIEIIRAAG
KQVVLDTSGEALRYGLAASPTIAKPNLAELEQFVGYPLTSEQAAAKAGRELLSHGIKLVVISMGEHGALFLDNAQSLVAI
PPSVAVQSTVGAGDAMVSGLVAAQTQGLDLAASARLATAFAAAKITQLGSNLPAAEIVEQIRADVVIRPCNAQLDVLQRG
ANQLKGVPL

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=266, Percent_Identity=34.9624060150376, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788017, Length=304, Percent_Identity=27.6315789473684, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 34837; Mature: 34706

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVTLTLNPAIDQTIFINNFQLETVNRAYDLKSHAGGKGVNVASLLAANGHKVVATGFL
CEEEEEEECCCCCCEEEEECEEEEEHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECC
GDQNTELFDKLFAEKQIDDQFIRIPGQPRVGIKISDQQTQRTTEINLPGLTPTNEQLDAI
CCCCHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHH
RATIKRLAADDNQWFILAGNVPPGIPSTIYGQLIEIIRAAGKQVVLDTSGEALRYGLAAS
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHEECCCCC
PTIAKPNLAELEQFVGYPLTSEQAAAKAGRELLSHGIKLVVISMGEHGALFLDNAQSLVA
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEECCCEEEE
IPPSVAVQSTVGAGDAMVSGLVAAQTQGLDLAASARLATAFAAAKITQLGSNLPAAEIVE
CCCCHHECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QIRADVVIRPCNAQLDVLQRGANQLKGVPL
HHHHCEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIVTLTLNPAIDQTIFINNFQLETVNRAYDLKSHAGGKGVNVASLLAANGHKVVATGFL
EEEEEEECCCCCCEEEEECEEEEEHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECC
GDQNTELFDKLFAEKQIDDQFIRIPGQPRVGIKISDQQTQRTTEINLPGLTPTNEQLDAI
CCCCHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHH
RATIKRLAADDNQWFILAGNVPPGIPSTIYGQLIEIIRAAGKQVVLDTSGEALRYGLAAS
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHEECCCCC
PTIAKPNLAELEQFVGYPLTSEQAAAKAGRELLSHGIKLVVISMGEHGALFLDNAQSLVA
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEECCCEEEE
IPPSVAVQSTVGAGDAMVSGLVAAQTQGLDLAASARLATAFAAAKITQLGSNLPAAEIVE
CCCCHHECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QIRADVVIRPCNAQLDVLQRGANQLKGVPL
HHHHCEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850730; 2254279 [H]