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The map label for this gene is regA [H]

Identifier: 159901223

GI number: 159901223

Start: 6017093

End: 6018097

Strand: Reverse

Name: regA [H]

Synonym: Haur_4711

Alternate gene names: 159901223

Gene position: 6018097-6017093 (Counterclockwise)

Preceding gene: 159901228

Following gene: 159901222

Centisome position: 94.82

GC content: 52.44

Gene sequence:

>1005_bases
ATGTCTAGCATCAAAGATGTTGCCAAAGCAGCCAATGTTTCAACGGCGACAGTTTCGCGGGTTTTGGCCAATCATCCGCA
TGTGCGGCAAGAGGTGCGCGAACGGGTGTTAGCGGCGGTGGCTCAGCTCGAATATCGGCCTAATTTGATTGCCCGCAATT
TGCGTTCGCAGCAATCCAACACCTTGGGCTTGATCGTTTCAGATATTCGTAATCCCTTTTTTACCGCCGTTAGCCGTGCC
GTCGAAGATACGGCCTATGCCCATGGCTACAATGTGCTGCTCTGCAACACCGATGAAAATCCCGAAAAAGAATTGCTGTA
TTTGCAACTGATGGGCGACGAGCAAGTGGCTGGGGTGATTTTCTCGCCCACCTTACAAACCCTCAATCGCTTTCATGAAT
TGAATTTGAGCTTTCCGACCGTATTAATCGACCGTTCGTTGCGCAGTGGCGATGTTGATGCCGTGCTGTTGGATAATGTG
AGCGCTGGTTATACCTTGGCCCAACATCTGATCAATCAAGGCTATCGGCGGATTGGGGCGATTTTTGGTGAGGCCAGCAC
GACTGGGCGCGAACGCCAACGCGGCTTTGAAGATGCCTTGCGCGATGCAGGCATCAGCATGCAGCCCGAATATTTGCGCT
TTGTGCGACCACGCAGCGAAGCTGGCCATAGCACAACCTTGGATCTCTTGCGTTTGCCGCAACCACCAGAGGCCATTTTT
ACTAGCAATAGCTTACTGACGGCTGGCGCACTTCAAGCCATTCGTGAACGGCGTTTGCAGATGCCTGAGCAAATTGGCTT
GGTTGGTTTCGATGATACAGCTTGGGCCAGTTTGGTGCAGCCAGCGATAACTGTTTTAGCCCAACCAACCGATGAAATTG
GCCGCTCAGCGACGGAATTAGTCTTGCAACGGGTGGCAGACCCACAACGGCCAACCCGCAAAATCATTTTGCAAGGCGAG
CTGATTGTGCGCGAATCGAGTGTTGAGCAGCGGGTAAGAGCCTAA

Upstream 100 bases:

>100_bases
AATCGATTACAATACATCCTAAGAAAAAGCGCACTAATCTGCTATAATGCCGCAATCGTTTTCAGCACTGCAATCGACTA
CTGCCAAGGGGAGTCTCGCT

Downstream 100 bases:

>100_bases
TTTTTAACCACGAAGGACACGAAGAACCACGAAGGTAACTAACTTCGTGTCCTTTGTGCGCTTCGTGATTAAATTTCATA
CTTCAGCATTCATCCTTGCT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSSIKDVAKAANVSTATVSRVLANHPHVRQEVRERVLAAVAQLEYRPNLIARNLRSQQSNTLGLIVSDIRNPFFTAVSRA
VEDTAYAHGYNVLLCNTDENPEKELLYLQLMGDEQVAGVIFSPTLQTLNRFHELNLSFPTVLIDRSLRSGDVDAVLLDNV
SAGYTLAQHLINQGYRRIGAIFGEASTTGRERQRGFEDALRDAGISMQPEYLRFVRPRSEAGHSTTLDLLRLPQPPEAIF
TSNSLLTAGALQAIRERRLQMPEQIGLVGFDDTAWASLVQPAITVLAQPTDEIGRSATELVLQRVADPQRPTRKIILQGE
LIVRESSVEQRVRA

Sequences:

>Translated_334_residues
MSSIKDVAKAANVSTATVSRVLANHPHVRQEVRERVLAAVAQLEYRPNLIARNLRSQQSNTLGLIVSDIRNPFFTAVSRA
VEDTAYAHGYNVLLCNTDENPEKELLYLQLMGDEQVAGVIFSPTLQTLNRFHELNLSFPTVLIDRSLRSGDVDAVLLDNV
SAGYTLAQHLINQGYRRIGAIFGEASTTGRERQRGFEDALRDAGISMQPEYLRFVRPRSEAGHSTTLDLLRLPQPPEAIF
TSNSLLTAGALQAIRERRLQMPEQIGLVGFDDTAWASLVQPAITVLAQPTDEIGRSATELVLQRVADPQRPTRKIILQGE
LIVRESSVEQRVRA
>Mature_333_residues
SSIKDVAKAANVSTATVSRVLANHPHVRQEVRERVLAAVAQLEYRPNLIARNLRSQQSNTLGLIVSDIRNPFFTAVSRAV
EDTAYAHGYNVLLCNTDENPEKELLYLQLMGDEQVAGVIFSPTLQTLNRFHELNLSFPTVLIDRSLRSGDVDAVLLDNVS
AGYTLAQHLINQGYRRIGAIFGEASTTGRERQRGFEDALRDAGISMQPEYLRFVRPRSEAGHSTTLDLLRLPQPPEAIFT
SNSLLTAGALQAIRERRLQMPEQIGLVGFDDTAWASLVQPAITVLAQPTDEIGRSATELVLQRVADPQRPTRKIILQGEL
IVRESSVEQRVRA

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=328, Percent_Identity=33.2317073170732, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=30.5389221556886, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=32.0359281437126, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=32.9896907216495, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=31.7220543806647, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789068, Length=332, Percent_Identity=30.421686746988, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=27.0440251572327, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787906, Length=334, Percent_Identity=28.1437125748503, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994940, Length=309, Percent_Identity=26.8608414239482, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786268, Length=320, Percent_Identity=25.3125, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=26.6025641025641, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786540, Length=305, Percent_Identity=26.5573770491803, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789456, Length=332, Percent_Identity=25.3012048192771, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=23.7082066869301, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790192, Length=253, Percent_Identity=25.296442687747, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37043; Mature: 36911

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIKDVAKAANVSTATVSRVLANHPHVRQEVRERVLAAVAQLEYRPNLIARNLRSQQSN
CCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
TLGLIVSDIRNPFFTAVSRAVEDTAYAHGYNVLLCNTDENPEKELLYLQLMGDEQVAGVI
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEEEEEECCCCCCCEE
FSPTLQTLNRFHELNLSFPTVLIDRSLRSGDVDAVLLDNVSAGYTLAQHLINQGYRRIGA
ECHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
IFGEASTTGRERQRGFEDALRDAGISMQPEYLRFVRPRSEAGHSTTLDLLRLPQPPEAIF
HHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHC
TSNSLLTAGALQAIRERRLQMPEQIGLVGFDDTAWASLVQPAITVLAQPTDEIGRSATEL
CCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VLQRVADPQRPTRKIILQGELIVRESSVEQRVRA
HHHHHCCCCCCCHHEEEECCEEEEHHHHHHHHCC
>Mature Secondary Structure 
SSIKDVAKAANVSTATVSRVLANHPHVRQEVRERVLAAVAQLEYRPNLIARNLRSQQSN
CHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
TLGLIVSDIRNPFFTAVSRAVEDTAYAHGYNVLLCNTDENPEKELLYLQLMGDEQVAGVI
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEEEEEECCCCCCCEE
FSPTLQTLNRFHELNLSFPTVLIDRSLRSGDVDAVLLDNVSAGYTLAQHLINQGYRRIGA
ECHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
IFGEASTTGRERQRGFEDALRDAGISMQPEYLRFVRPRSEAGHSTTLDLLRLPQPPEAIF
HHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHC
TSNSLLTAGALQAIRERRLQMPEQIGLVGFDDTAWASLVQPAITVLAQPTDEIGRSATEL
CCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VLQRVADPQRPTRKIILQGELIVRESSVEQRVRA
HHHHHCCCCCCCHHEEEECCEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]