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The map label for this gene is rsbRA [H]

Identifier: 159901210

GI number: 159901210

Start: 6002559

End: 6003650

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_4698

Alternate gene names: 159901210

Gene position: 6002559-6003650 (Clockwise)

Preceding gene: 159901209

Following gene: 159901211

Centisome position: 94.58

GC content: 51.1

Gene sequence:

>1092_bases
GTGAAACGTTTTTTTCAACAATGGCTTCATTCGCTCAATTATCCCGACCCCGTTCAACAGCAGCAAGCCCAAATTATGCA
GGGCATTCTTTTGGGTTCGTTTATGGCTAGCACTGGTGCGTTAATTGTGCCATTTGTGGCCCCAGTAACCTTCGTTCAAT
CAATCGGTATTGCGCTGGCAATCGGTGCCGCAATTATGATTTTTCTGGTAGCTTTATTACTGCTGCGGCGCAATTATTTT
AAATTGGCGCTCTTTGGTAGCGTTTTTGGTTTATCGTTCTTTTTACTGATTATGTTGCTTGGCACTGGCTTAGCTGATAG
CGGCGCGATTATTTTTGGTTTGGCTGTGCCCATGGCTTTGGCTAGTTTGCTCAGTGGTCGCAAATTAACATTCGTGATGA
TTGGTGTTGGCCTTTTTGGCTTGATAGCCACTGCCCTGGCCGAAGCTTTCGTGCCGCAGATCACGGGCTTTGCCAAGCCC
ATGGATAAAAACTATGGCGGAATTATTGGTGGATATACCGCAGTTGCCTTGGTGCTTGGTATGGTCTTATCACGCTATAG
CAGCGCCTTATCAACCGCGCTCGATGCTGCTCGTACCCGCCAAACCGAGCTTGAGCAACTCCAAGCGAGCCTTGAACAAA
CGGTTGCTGAACGCACTGCCACCTTGCAAAATACCCTTGCCGAGCTAAAACAACGGGCATCCGAGCAAGCTCAATTGCTT
GAAGCCAATCAGCAACAGGCTGTGGTTATTCGCGAGTTGGGTGTGCCTGTGATTCCGCTTGGTGGTCGGCGTTTGGTTGT
GCCCTTGGTCGGCCAGCTGGATCAAGCGCGTTTGAATACAATTCGTGAGCGAGTGATCACCGCCGTAGTGCAACAACGTG
CTCGCCAAGTGCTGCTCGATGTAACCGGCGTGCCCTTGGTTGATGTGCATATGGCTGGCGAATTGGCCGCCGTTATTGCC
GCGACCAGCCTCGTTGGCGCGGAAACCGCGCTCGTCGGCATCAACCCCGATGTTGCCCAAGGTTTGGTTGGCTCGGGCAT
TGATGTTTCGCGCTTGCCAGCCTTCGCTACTTTAGAACAAGCATTGAATTAG

Upstream 100 bases:

>100_bases
ACTGTTAGCAAGGTGTAAGCTGAGGCTAACCAAGCCTACAAACGAAGGTGGTACAATAGCGCTAGACTATCCCTACAATC
CACACCCTGAGGAGCCACCC

Downstream 100 bases:

>100_bases
TTGCCGCATCGTTGTAGTTGGGGGAATGGTCGATGGCGCTTGAGCAATCCACACGGGCATTGGTGATTGGTGGTTGTGGC
TTTGTCGGCAAACATTTGGT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKRFFQQWLHSLNYPDPVQQQQAQIMQGILLGSFMASTGALIVPFVAPVTFVQSIGIALAIGAAIMIFLVALLLLRRNYF
KLALFGSVFGLSFFLLIMLLGTGLADSGAIIFGLAVPMALASLLSGRKLTFVMIGVGLFGLIATALAEAFVPQITGFAKP
MDKNYGGIIGGYTAVALVLGMVLSRYSSALSTALDAARTRQTELEQLQASLEQTVAERTATLQNTLAELKQRASEQAQLL
EANQQQAVVIRELGVPVIPLGGRRLVVPLVGQLDQARLNTIRERVITAVVQQRARQVLLDVTGVPLVDVHMAGELAAVIA
ATSLVGAETALVGINPDVAQGLVGSGIDVSRLPAFATLEQALN

Sequences:

>Translated_363_residues
MKRFFQQWLHSLNYPDPVQQQQAQIMQGILLGSFMASTGALIVPFVAPVTFVQSIGIALAIGAAIMIFLVALLLLRRNYF
KLALFGSVFGLSFFLLIMLLGTGLADSGAIIFGLAVPMALASLLSGRKLTFVMIGVGLFGLIATALAEAFVPQITGFAKP
MDKNYGGIIGGYTAVALVLGMVLSRYSSALSTALDAARTRQTELEQLQASLEQTVAERTATLQNTLAELKQRASEQAQLL
EANQQQAVVIRELGVPVIPLGGRRLVVPLVGQLDQARLNTIRERVITAVVQQRARQVLLDVTGVPLVDVHMAGELAAVIA
ATSLVGAETALVGINPDVAQGLVGSGIDVSRLPAFATLEQALN
>Mature_363_residues
MKRFFQQWLHSLNYPDPVQQQQAQIMQGILLGSFMASTGALIVPFVAPVTFVQSIGIALAIGAAIMIFLVALLLLRRNYF
KLALFGSVFGLSFFLLIMLLGTGLADSGAIIFGLAVPMALASLLSGRKLTFVMIGVGLFGLIATALAEAFVPQITGFAKP
MDKNYGGIIGGYTAVALVLGMVLSRYSSALSTALDAARTRQTELEQLQASLEQTVAERTATLQNTLAELKQRASEQAQLL
EANQQQAVVIRELGVPVIPLGGRRLVVPLVGQLDQARLNTIRERVITAVVQQRARQVLLDVTGVPLVDVHMAGELAAVIA
ATSLVGAETALVGINPDVAQGLVGSGIDVSRLPAFATLEQALN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 38502; Mature: 38502

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFFQQWLHSLNYPDPVQQQQAQIMQGILLGSFMASTGALIVPFVAPVTFVQSIGIALA
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IGAAIMIFLVALLLLRRNYFKLALFGSVFGLSFFLLIMLLGTGLADSGAIIFGLAVPMAL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ASLLSGRKLTFVMIGVGLFGLIATALAEAFVPQITGFAKPMDKNYGGIIGGYTAVALVLG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
MVLSRYSSALSTALDAARTRQTELEQLQASLEQTVAERTATLQNTLAELKQRASEQAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EANQQQAVVIRELGVPVIPLGGRRLVVPLVGQLDQARLNTIRERVITAVVQQRARQVLLD
HCCCHHHHHHHHCCCCEECCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGVPLVDVHMAGELAAVIAATSLVGAETALVGINPDVAQGLVGSGIDVSRLPAFATLEQ
HCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHHHH
ALN
HCC
>Mature Secondary Structure
MKRFFQQWLHSLNYPDPVQQQQAQIMQGILLGSFMASTGALIVPFVAPVTFVQSIGIALA
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IGAAIMIFLVALLLLRRNYFKLALFGSVFGLSFFLLIMLLGTGLADSGAIIFGLAVPMAL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ASLLSGRKLTFVMIGVGLFGLIATALAEAFVPQITGFAKPMDKNYGGIIGGYTAVALVLG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
MVLSRYSSALSTALDAARTRQTELEQLQASLEQTVAERTATLQNTLAELKQRASEQAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EANQQQAVVIRELGVPVIPLGGRRLVVPLVGQLDQARLNTIRERVITAVVQQRARQVLLD
HCCCHHHHHHHHCCCCEECCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGVPLVDVHMAGELAAVIAATSLVGAETALVGINPDVAQGLVGSGIDVSRLPAFATLEQ
HCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCHHHHHHHHHHHH
ALN
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]