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The map label for this gene is infC [H]

Identifier: 159901151

GI number: 159901151

Start: 5927698

End: 5928357

Strand: Reverse

Name: infC [H]

Synonym: Haur_4639

Alternate gene names: 159901151

Gene position: 5928357-5927698 (Counterclockwise)

Preceding gene: 159901153

Following gene: 159901150

Centisome position: 93.41

GC content: 51.36

Gene sequence:

>660_bases
TTGTGTTTTGATGTCCTTTTTTGGAAGGAGCCTCCTATCAGAGACAAGCTACGAATCAATAATCGGATTCGCGTGCGTGA
AGTGCGTCTGATCGACGAAAACGGGAACCAAGTTGGGATCATCACGACCCGTGATGCACTCGACATGGCACATGACCGCG
ATCTCGACTTAGTTGAGGTTGCCCCGAATGCTAGCCCGCCGGTTTGCCGCCTTATGGATTACGGCAAGTACCGCTACGAG
CAAACCAAGAAAGAACGCGAAGCCCGCAAGAATCAAAAACAGGTCGAACTGAAAGAGATTCGCATGCAGCCGCGCACCGA
CACCCATGACTTGCAGGTAAAGGTGAACAATGCTCGCCGTTTCCTCGAAGAAGGGCATAAAGTGAAGTTCTCGGTACGTT
TCCGTGGGCGTGAAATCACTCACCCTGAAATTGGCCGCGAAATGCTCGAGCAAATTGCCGAGGATTTACGCGATCATGGG
GTGCTTGAGCAAAAACCCACGCTCGAAGGTCGGGCCTATTCGTTGATCATGGCCCCATCACCAAGCAAAACGCAGCCTGC
GAAACGTAGCGATAAACCGGCTCCACCATTATCATCATTAGGAGATATTGATTTCGATGCCGAAGATGAAGACCAACAAG
CAGGCCAAGCGCCGCTTTAA

Upstream 100 bases:

>100_bases
TTTAATCGAATAGCCTAAAAAGCTTTGACTTATCGCCTAGAATATGCTATAGTTGGCAAGCCAACACCCTAACGCTGATG
AGGTCGCGTTTAGGGCTTTG

Downstream 100 bases:

>100_bases
AATCACTGGCACCGGTAAGATTATGCGCACCAAGGGTGGCAAAAGCCACTTCCGCCGCCGCAAATCAACCCGTGTCAAGC
AGGCTCTCGATAAGATGTTC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MCFDVLFWKEPPIRDKLRINNRIRVREVRLIDENGNQVGIITTRDALDMAHDRDLDLVEVAPNASPPVCRLMDYGKYRYE
QTKKEREARKNQKQVELKEIRMQPRTDTHDLQVKVNNARRFLEEGHKVKFSVRFRGREITHPEIGREMLEQIAEDLRDHG
VLEQKPTLEGRAYSLIMAPSPSKTQPAKRSDKPAPPLSSLGDIDFDAEDEDQQAGQAPL

Sequences:

>Translated_219_residues
MCFDVLFWKEPPIRDKLRINNRIRVREVRLIDENGNQVGIITTRDALDMAHDRDLDLVEVAPNASPPVCRLMDYGKYRYE
QTKKEREARKNQKQVELKEIRMQPRTDTHDLQVKVNNARRFLEEGHKVKFSVRFRGREITHPEIGREMLEQIAEDLRDHG
VLEQKPTLEGRAYSLIMAPSPSKTQPAKRSDKPAPPLSSLGDIDFDAEDEDQQAGQAPL
>Mature_219_residues
MCFDVLFWKEPPIRDKLRINNRIRVREVRLIDENGNQVGIITTRDALDMAHDRDLDLVEVAPNASPPVCRLMDYGKYRYE
QTKKEREARKNQKQVELKEIRMQPRTDTHDLQVKVNNARRFLEEGHKVKFSVRFRGREITHPEIGREMLEQIAEDLRDHG
VLEQKPTLEGRAYSLIMAPSPSKTQPAKRSDKPAPPLSSLGDIDFDAEDEDQQAGQAPL

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=49.6932515337423, Blast_Score=156, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 25365; Mature: 25365

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFDVLFWKEPPIRDKLRINNRIRVREVRLIDENGNQVGIITTRDALDMAHDRDLDLVEV
CCEEEEEECCCCCCHHEECCCEEEEEEEEEEECCCCEEEEEEEHHHHHHHCCCCCCEEEE
APNASPPVCRLMDYGKYRYEQTKKEREARKNQKQVELKEIRMQPRTDTHDLQVKVNNARR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHH
FLEEGHKVKFSVRFRGREITHPEIGREMLEQIAEDLRDHGVLEQKPTLEGRAYSLIMAPS
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
PSKTQPAKRSDKPAPPLSSLGDIDFDAEDEDQQAGQAPL
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MCFDVLFWKEPPIRDKLRINNRIRVREVRLIDENGNQVGIITTRDALDMAHDRDLDLVEV
CCEEEEEECCCCCCHHEECCCEEEEEEEEEEECCCCEEEEEEEHHHHHHHCCCCCCEEEE
APNASPPVCRLMDYGKYRYEQTKKEREARKNQKQVELKEIRMQPRTDTHDLQVKVNNARR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHH
FLEEGHKVKFSVRFRGREITHPEIGREMLEQIAEDLRDHGVLEQKPTLEGRAYSLIMAPS
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
PSKTQPAKRSDKPAPPLSSLGDIDFDAEDEDQQAGQAPL
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]