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The map label for this gene is bcd [H]

Identifier: 159901122

GI number: 159901122

Start: 5895351

End: 5896490

Strand: Direct

Name: bcd [H]

Synonym: Haur_4610

Alternate gene names: 159901122

Gene position: 5895351-5896490 (Clockwise)

Preceding gene: 159901121

Following gene: 159901123

Centisome position: 92.89

GC content: 50.09

Gene sequence:

>1140_bases
GTGGATTTCAAGCTCTCGGACGATCAGGAATTTATGCGTAAAGCGGCTCGCGAATTTGCCGAAGGTGAAATTCGGGCAAC
AGTTGCTGAGCGTGATGAGCATAAAATTTGGCCGACTGACATTGTGCAAAAGATGGGCCAATTGGGCTTTATGGGCGTGG
CGATCGATGAAGCCTACGGTGGAGCAGGCCTCGATTACGTTTCATATGCAATTATGATCGAGGAGCTTTCACGGGTTGAT
GCCTCGGTTGGGGTCATTGCCTCGGTCAATAATTCATTGGTATGTGCTGGGATTGAAAAATTTGGCACTGAAGAACAAAA
ACGTGATATCCTAGCCCCCTTGGCTAGTGGCCAAAAACTCGGCGCTTTCTCGCTCTCAGAGCCTGGCGCAGGCTCGGATG
CGGCGGCCCAGAAAACCCGCGCTGTTGAAGATGGCGATTACTACATCATTACGGGCACCAAAAACTGGGTTACCAATGGC
TCAAAAGCCGACACAATTTTGTTGATGACCATGACTGCCCCAGAAAAAGGAGTCAAAGGCATCACCGCATTTTTAATTGA
TACCCATGAGCCAGGCGTTTCAATCCTTAAGGTTGAAGATAAATTGGGCATTCGTTCGGCGCAATCGGCTCAAATGTCGT
ATGATGGCTATCGAGTGCACAAAAGCCGCATGCTCGGCCAACCTGGCGAAGGCTTCAAAATCGCTATGACGATCTTGAAT
GGTGGACGGATTGGCATCGCCTCGCAGGCCTTGGGGATTGCCCAAGGAGCCTATGAAGCGGCCCTGGATTATGCCAAAGT
CCGCGAACAATTTGGCCAATCGATCATCAATTTTCAAGCGGTGGGTTTTACCTTAGCCGATATGGCGACGCGAATTAAAG
CTGCTCGGATGTTGACCTATCATGCGGCATGGCTTAAAGATCAGGGCGAGAATTATATTGCGGCGGCGGCGATGGCCAAA
GTTTATGCCTCGGAAACCGCCATGTGGACAGCCACCAAAGCCGTGCAAATCTTCGGCTCGAACGGCTACTCCAAAGAATA
TCCGGTTGAACGCTACTTCCGCGATGCCAAGATCACCGAAATTTATGAAGGCACGAGTGAAATTCAACGCTTGGTAATTT
CGCGCGAGATTGCCAAATAA

Upstream 100 bases:

>100_bases
CCCTTGCGCAGTTTAGTGCGCTGGGTCGATTTAGAACGATCAGCCGATCCTCGCGTATAATCACGATTAAGCGCATTCGA
CAGATTTTGGAGGAATCAAC

Downstream 100 bases:

>100_bases
AACGCTACGTGCTCAGCCAGCATCAACGATGCTGGCTGATTATTTAACCACTCTTTAATCATTAGGCTGCTTGATCTGCT
TGCAAAGCTGTGATGGACAG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDFKLSDDQEFMRKAAREFAEGEIRATVAERDEHKIWPTDIVQKMGQLGFMGVAIDEAYGGAGLDYVSYAIMIEELSRVD
ASVGVIASVNNSLVCAGIEKFGTEEQKRDILAPLASGQKLGAFSLSEPGAGSDAAAQKTRAVEDGDYYIITGTKNWVTNG
SKADTILLMTMTAPEKGVKGITAFLIDTHEPGVSILKVEDKLGIRSAQSAQMSYDGYRVHKSRMLGQPGEGFKIAMTILN
GGRIGIASQALGIAQGAYEAALDYAKVREQFGQSIINFQAVGFTLADMATRIKAARMLTYHAAWLKDQGENYIAAAAMAK
VYASETAMWTATKAVQIFGSNGYSKEYPVERYFRDAKITEIYEGTSEIQRLVISREIAK

Sequences:

>Translated_379_residues
MDFKLSDDQEFMRKAAREFAEGEIRATVAERDEHKIWPTDIVQKMGQLGFMGVAIDEAYGGAGLDYVSYAIMIEELSRVD
ASVGVIASVNNSLVCAGIEKFGTEEQKRDILAPLASGQKLGAFSLSEPGAGSDAAAQKTRAVEDGDYYIITGTKNWVTNG
SKADTILLMTMTAPEKGVKGITAFLIDTHEPGVSILKVEDKLGIRSAQSAQMSYDGYRVHKSRMLGQPGEGFKIAMTILN
GGRIGIASQALGIAQGAYEAALDYAKVREQFGQSIINFQAVGFTLADMATRIKAARMLTYHAAWLKDQGENYIAAAAMAK
VYASETAMWTATKAVQIFGSNGYSKEYPVERYFRDAKITEIYEGTSEIQRLVISREIAK
>Mature_379_residues
MDFKLSDDQEFMRKAAREFAEGEIRATVAERDEHKIWPTDIVQKMGQLGFMGVAIDEAYGGAGLDYVSYAIMIEELSRVD
ASVGVIASVNNSLVCAGIEKFGTEEQKRDILAPLASGQKLGAFSLSEPGAGSDAAAQKTRAVEDGDYYIITGTKNWVTNG
SKADTILLMTMTAPEKGVKGITAFLIDTHEPGVSILKVEDKLGIRSAQSAQMSYDGYRVHKSRMLGQPGEGFKIAMTILN
GGRIGIASQALGIAQGAYEAALDYAKVREQFGQSIINFQAVGFTLADMATRIKAARMLTYHAAWLKDQGENYIAAAAMAK
VYASETAMWTATKAVQIFGSNGYSKEYPVERYFRDAKITEIYEGTSEIQRLVISREIAK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=48.4042553191489, Blast_Score=357, Evalue=7e-99,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=43.6997319034853, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=36.5333333333333, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=37.6315789473684, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=37.6315789473684, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=34.4, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=35.4285714285714, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI21361497, Length=384, Percent_Identity=35.9375, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI76496475, Length=340, Percent_Identity=37.0588235294118, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4557235, Length=340, Percent_Identity=37.6470588235294, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=31.7333333333333, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=31.3157894736842, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI7669494, Length=366, Percent_Identity=30.8743169398907, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI48976061, Length=342, Percent_Identity=29.5321637426901, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI211971008, Length=342, Percent_Identity=29.5321637426901, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI38505218, Length=319, Percent_Identity=25.3918495297806, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1786223, Length=385, Percent_Identity=29.3506493506493, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=31.0077519379845, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI87082384, Length=280, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081702, Length=360, Percent_Identity=27.2222222222222, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=42.741935483871, Blast_Score=313, Evalue=8e-86,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=41.5549597855228, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=36.6754617414248, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=40, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=39.0501319261214, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=46.3768115942029, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=36.436170212766, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=36.0526315789474, Blast_Score=251, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI32563615, Length=253, Percent_Identity=41.897233201581, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=32.6760563380282, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=35.7664233576642, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=29.7872340425532, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=377, Percent_Identity=29.973474801061, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=28.686327077748, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71985192, Length=302, Percent_Identity=31.4569536423841, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=32.4022346368715, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=340, Percent_Identity=27.6470588235294, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=326, Percent_Identity=26.6871165644172, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=326, Percent_Identity=26.6871165644172, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=48, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=45.646437994723, Blast_Score=344, Evalue=6e-95,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=42.2872340425532, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=36.0103626943005, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=37.7308707124011, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=33.9285714285714, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=31.496062992126, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41235; Mature: 41235

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKLSDDQEFMRKAAREFAEGEIRATVAERDEHKIWPTDIVQKMGQLGFMGVAIDEAYG
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCCC
GAGLDYVSYAIMIEELSRVDASVGVIASVNNSLVCAGIEKFGTEEQKRDILAPLASGQKL
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHCCCHHHHHHHHHHCCCCCC
GAFSLSEPGAGSDAAAQKTRAVEDGDYYIITGTKNWVTNGSKADTILLMTMTAPEKGVKG
CEEECCCCCCCCCHHHHHHCCEECCCEEEEECCHHHCCCCCCCCEEEEEEECCCCCCCCC
ITAFLIDTHEPGVSILKVEDKLGIRSAQSAQMSYDGYRVHKSRMLGQPGEGFKIAMTILN
EEEEEEECCCCCEEEEEEEHHCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCEEEEEEEEC
GGRIGIASQALGIAQGAYEAALDYAKVREQFGQSIINFQAVGFTLADMATRIKAARMLTY
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HAAWLKDQGENYIAAAAMAKVYASETAMWTATKAVQIFGSNGYSKEYPVERYFRDAKITE
HHHHHHCCCCCEEHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCHHHHHCCCHHHH
IYEGTSEIQRLVISREIAK
HHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFKLSDDQEFMRKAAREFAEGEIRATVAERDEHKIWPTDIVQKMGQLGFMGVAIDEAYG
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCCC
GAGLDYVSYAIMIEELSRVDASVGVIASVNNSLVCAGIEKFGTEEQKRDILAPLASGQKL
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHCCCHHHHHHHHHHCCCCCC
GAFSLSEPGAGSDAAAQKTRAVEDGDYYIITGTKNWVTNGSKADTILLMTMTAPEKGVKG
CEEECCCCCCCCCHHHHHHCCEECCCEEEEECCHHHCCCCCCCCEEEEEEECCCCCCCCC
ITAFLIDTHEPGVSILKVEDKLGIRSAQSAQMSYDGYRVHKSRMLGQPGEGFKIAMTILN
EEEEEEECCCCCEEEEEEEHHCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCEEEEEEEEC
GGRIGIASQALGIAQGAYEAALDYAKVREQFGQSIINFQAVGFTLADMATRIKAARMLTY
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HAAWLKDQGENYIAAAAMAKVYASETAMWTATKAVQIFGSNGYSKEYPVERYFRDAKITE
HHHHHHCCCCCEEHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCHHHHHCCCHHHH
IYEGTSEIQRLVISREIAK
HHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]