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The map label for this gene is yccK [H]

Identifier: 159901098

GI number: 159901098

Start: 5867850

End: 5868842

Strand: Reverse

Name: yccK [H]

Synonym: Haur_4586

Alternate gene names: 159901098

Gene position: 5868842-5867850 (Counterclockwise)

Preceding gene: 159901099

Following gene: 159901096

Centisome position: 92.47

GC content: 51.16

Gene sequence:

>993_bases
ATGCTCAAGCGAACAATTGGCAAAAGTGGTATTGAAGTCAGTGCTTTGGGTTTAGGCTGTTGGGCCATCGGCGGCCCATT
CAATCACAATGGCAATCCCTCAGGTTGGGGCCAAGTTGACGATGCTGAATCAATTCAGGCAATTCATGCAGCGCTTGAGC
TTGGAGTCAATTTTCTCGATACTGCCAATGTCTATGGGTGTGGCCACAGCGAGCAAATTATTGCCCAAGCGATCGCTGGC
CGCCGTGATCAGGTGATTCTCGCCACTAAATTTGGCAATAGCTGGGCTGAAGGCAGCAAAGATTCGTTTGAGCAAATTCC
AATTAGCCCTGCCGAAATTCGCCAACAATTGGAAGCCAGCCTCAAACGGCTCAATACCGATTATGTCGATTTGTTACAAT
TTCACTTGTGGGGCTATCCGGTCGAAGATGCCGCCCCAGTGCGCGATACGCTTGAAAGTTTGGTGAGCGAGGGCAAAATT
CGCGGCTATGGTTGGAGCACCGATCGGCTTGATGCGATTAAGCTCTTTGCTGAAGGCCCACATTGTATTGCTGTGCAACA
ACAATTGAATTTATTGCATGGTCATAGCACGGGCGAGAGCGATGCAATTATCGCCTTTTGCGAAGCCCACAATTTAGCCA
GCATCAATCGTGCACCCTTAGCGATGGGTTTGTTGACAGGAAAATTCACCCCCACTACCAGCTTTAGCAGCGATGATGTA
CGCAGCAAAGTTGCATGGTTTGAGGGGTTTCAGGCCGGCAAGCCCAATCCTGAATGGCTCAAAAAGCTCGAAGCCTTGCG
CGAAGTGTTGACCAGCGAAGGCCGCACGCTGACTCAAGGTGCTTTAGCTTGGTTGTGGGGTCGCAGCAGCCAAACCCTGC
CAATCCCAGGCTTCCGTACCGTCGCTCAAGCCAGCGAAAACGCCAAAGCCTTACAATTCGGCCCATTGAACCCCAGCCAA
ATGCAGCAAATCGCTAGCATTTTGCAGGGCTAG

Upstream 100 bases:

>100_bases
AGGGGCTTTTTATATTGCCCAACATTGGGGTATTGACTTAGAGCGCACGCAAATGTTTAGAATGCCTGTAACGACGAATA
ACTAACTGGGAGACACACGC

Downstream 100 bases:

>100_bases
CGATACGTTTTTGATCCACGAAGAGCACGAAGGACACGAAACATGGCTCTAGGCTAACGAAATAATTTTAGAAATCACTG
ATCGTTGATAGCCAATAGTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLKRTIGKSGIEVSALGLGCWAIGGPFNHNGNPSGWGQVDDAESIQAIHAALELGVNFLDTANVYGCGHSEQIIAQAIAG
RRDQVILATKFGNSWAEGSKDSFEQIPISPAEIRQQLEASLKRLNTDYVDLLQFHLWGYPVEDAAPVRDTLESLVSEGKI
RGYGWSTDRLDAIKLFAEGPHCIAVQQQLNLLHGHSTGESDAIIAFCEAHNLASINRAPLAMGLLTGKFTPTTSFSSDDV
RSKVAWFEGFQAGKPNPEWLKKLEALREVLTSEGRTLTQGALAWLWGRSSQTLPIPGFRTVAQASENAKALQFGPLNPSQ
MQQIASILQG

Sequences:

>Translated_330_residues
MLKRTIGKSGIEVSALGLGCWAIGGPFNHNGNPSGWGQVDDAESIQAIHAALELGVNFLDTANVYGCGHSEQIIAQAIAG
RRDQVILATKFGNSWAEGSKDSFEQIPISPAEIRQQLEASLKRLNTDYVDLLQFHLWGYPVEDAAPVRDTLESLVSEGKI
RGYGWSTDRLDAIKLFAEGPHCIAVQQQLNLLHGHSTGESDAIIAFCEAHNLASINRAPLAMGLLTGKFTPTTSFSSDDV
RSKVAWFEGFQAGKPNPEWLKKLEALREVLTSEGRTLTQGALAWLWGRSSQTLPIPGFRTVAQASENAKALQFGPLNPSQ
MQQIASILQG
>Mature_330_residues
MLKRTIGKSGIEVSALGLGCWAIGGPFNHNGNPSGWGQVDDAESIQAIHAALELGVNFLDTANVYGCGHSEQIIAQAIAG
RRDQVILATKFGNSWAEGSKDSFEQIPISPAEIRQQLEASLKRLNTDYVDLLQFHLWGYPVEDAAPVRDTLESLVSEGKI
RGYGWSTDRLDAIKLFAEGPHCIAVQQQLNLLHGHSTGESDAIIAFCEAHNLASINRAPLAMGLLTGKFTPTTSFSSDDV
RSKVAWFEGFQAGKPNPEWLKKLEALREVLTSEGRTLTQGALAWLWGRSSQTLPIPGFRTVAQASENAKALQFGPLNPSQ
MQQIASILQG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=27.2988505747126, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4504825, Length=345, Percent_Identity=27.2463768115942, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI27436962, Length=346, Percent_Identity=26.3005780346821, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436964, Length=346, Percent_Identity=26.3005780346821, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436966, Length=346, Percent_Identity=26.3005780346821, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436971, Length=346, Percent_Identity=25.7225433526012, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788070, Length=343, Percent_Identity=29.1545189504373, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081735, Length=339, Percent_Identity=31.2684365781711, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789375, Length=347, Percent_Identity=28.8184438040346, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788081, Length=318, Percent_Identity=25.7861635220126, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=27.3927392739274, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=24.4956772334294, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=250, Percent_Identity=28, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=344, Percent_Identity=28.7790697674419, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=24.0963855421687, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=310, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321052, Length=162, Percent_Identity=31.4814814814815, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646155, Length=233, Percent_Identity=31.3304721030043, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646159, Length=187, Percent_Identity=31.0160427807487, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35761; Mature: 35761

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRTIGKSGIEVSALGLGCWAIGGPFNHNGNPSGWGQVDDAESIQAIHAALELGVNFLD
CCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHC
TANVYGCGHSEQIIAQAIAGRRDQVILATKFGNSWAEGSKDSFEQIPISPAEIRQQLEAS
CCCEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHH
LKRLNTDYVDLLQFHLWGYPVEDAAPVRDTLESLVSEGKIRGYGWSTDRLDAIKLFAEGP
HHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCHHHHHHCCCCC
HCIAVQQQLNLLHGHSTGESDAIIAFCEAHNLASINRAPLAMGLLTGKFTPTTSFSSDDV
CEEEHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHH
RSKVAWFEGFQAGKPNPEWLKKLEALREVLTSEGRTLTQGALAWLWGRSSQTLPIPGFRT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCHHH
VAQASENAKALQFGPLNPSQMQQIASILQG
HHHHCCCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLKRTIGKSGIEVSALGLGCWAIGGPFNHNGNPSGWGQVDDAESIQAIHAALELGVNFLD
CCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHC
TANVYGCGHSEQIIAQAIAGRRDQVILATKFGNSWAEGSKDSFEQIPISPAEIRQQLEAS
CCCEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHH
LKRLNTDYVDLLQFHLWGYPVEDAAPVRDTLESLVSEGKIRGYGWSTDRLDAIKLFAEGP
HHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCHHHHHHCCCCC
HCIAVQQQLNLLHGHSTGESDAIIAFCEAHNLASINRAPLAMGLLTGKFTPTTSFSSDDV
CEEEHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHH
RSKVAWFEGFQAGKPNPEWLKKLEALREVLTSEGRTLTQGALAWLWGRSSQTLPIPGFRT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCHHH
VAQASENAKALQFGPLNPSQMQQIASILQG
HHHHCCCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]