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The map label for this gene is cdd [H]

Identifier: 159901099

GI number: 159901099

Start: 5868986

End: 5869393

Strand: Reverse

Name: cdd [H]

Synonym: Haur_4587

Alternate gene names: 159901099

Gene position: 5869393-5868986 (Counterclockwise)

Preceding gene: 159901100

Following gene: 159901098

Centisome position: 92.48

GC content: 53.43

Gene sequence:

>408_bases
ATGATGGTTGACTACCAAGCCCTGTTAGCCAACGCCAAAACCGCCCGCGAACGAGCTTACACGCCCTACTCACGTTTCAA
AGTTGGCGCAGCAGTGCTGACGGCCAGCGGACAAATATTCCATGGTTGTAATATTGAAAACGCCGCCTATCCGGTCTGTT
TATGTGCTGAGCGTTCAGCCCTCGCTGCGGCTTGGAGCGCTGGCGAAACAGAATTTATCGCGTTAGCAGTTGTTGCCGAT
ACGCCTGGCCCAGTTGCGCCCTGTGGGATGTGTCGCCAATTTATGTTTGAGCTTGCTCCCGATCTGCCTGTGCTGTTGGC
AAATTTGGCTGAGCAAACCCAACATACCACGCCACGCGAGCTGCTACCTGGTGGATTTTCACCTGAAAGCCTAGCTCACA
ATCGTTAA

Upstream 100 bases:

>100_bases
ACAATTGAGGTTGTTACGATTCAAGGCTTGCGACCACAACGCCTACGCCTAAGCTTAGCCCATGCCGAACACGAGTTCGC
CGAGGTTGGGAGTAATACCG

Downstream 100 bases:

>100_bases
TCAAAGATCAAATGTGTATTCGACCAAAGCCCTTGTGTTGCACAGGGGCTTTTTATATTGCCCAACATTGGGGTATTGAC
TTAGAGCGCACGCAAATGTT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MMVDYQALLANAKTARERAYTPYSRFKVGAAVLTASGQIFHGCNIENAAYPVCLCAERSALAAAWSAGETEFIALAVVAD
TPGPVAPCGMCRQFMFELAPDLPVLLANLAEQTQHTTPRELLPGGFSPESLAHNR

Sequences:

>Translated_135_residues
MMVDYQALLANAKTARERAYTPYSRFKVGAAVLTASGQIFHGCNIENAAYPVCLCAERSALAAAWSAGETEFIALAVVAD
TPGPVAPCGMCRQFMFELAPDLPVLLANLAEQTQHTTPRELLPGGFSPESLAHNR
>Mature_135_residues
MMVDYQALLANAKTARERAYTPYSRFKVGAAVLTASGQIFHGCNIENAAYPVCLCAERSALAAAWSAGETEFIALAVVAD
TPGPVAPCGMCRQFMFELAPDLPVLLANLAEQTQHTTPRELLPGGFSPESLAHNR

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=131, Percent_Identity=45.0381679389313, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788465, Length=113, Percent_Identity=37.1681415929204, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540514, Length=121, Percent_Identity=49.5867768595041, Blast_Score=118, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17551074, Length=126, Percent_Identity=42.0634920634921, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=130, Percent_Identity=40, Blast_Score=95, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=47.65625, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920920, Length=106, Percent_Identity=52.8301886792453, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24582744, Length=107, Percent_Identity=50.4672897196262, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14442; Mature: 14442

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVDYQALLANAKTARERAYTPYSRFKVGAAVLTASGQIFHGCNIENAAYPVCLCAERSA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCEEECCCCCCCCCCEEEECCCHH
LAAAWSAGETEFIALAVVADTPGPVAPCGMCRQFMFELAPDLPVLLANLAEQTQHTTPRE
HHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
LLPGGFSPESLAHNR
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MMVDYQALLANAKTARERAYTPYSRFKVGAAVLTASGQIFHGCNIENAAYPVCLCAERSA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCEEECCCCCCCCCCEEEECCCHH
LAAAWSAGETEFIALAVVADTPGPVAPCGMCRQFMFELAPDLPVLLANLAEQTQHTTPRE
HHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
LLPGGFSPESLAHNR
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]