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The map label for this gene is yfkJ [H]

Identifier: 159901096

GI number: 159901096

Start: 5865483

End: 5865947

Strand: Reverse

Name: yfkJ [H]

Synonym: Haur_4584

Alternate gene names: 159901096

Gene position: 5865947-5865483 (Counterclockwise)

Preceding gene: 159901098

Following gene: 159901092

Centisome position: 92.43

GC content: 46.88

Gene sequence:

>465_bases
ATGGTTCGGGTCTTATTTGTTTGTTTAGGCAATATTTGTCGTTCGCCAATGGCTGAGGGCATTATGCGCCACTTGGTCGA
GCAACGAAAGCTTAGTCATGCGATCGAAGTCGATTCGGCGGGCACGAGCCATTATCATATTGGCGATGATCCGCACCACG
GAACTATGCGCATTTTGCGCCATAATGGCATTAGCTTGAGCCATCGGGGCCGCCAATTTGGCAAAATTGATCAACAGAAT
TTTGATTATTTGATCGCGATGGATACCCAAAATCGGCATGATATGCAGGCGGTTTTAGGCTCAAACGGGGCTGAGGTACG
CTTGATGCTTGATTATATTCCCAACGGAGTCAAAGGCCGCGATGTGCCAGACCCTTGGTATACTGGCAATTTTGAAGAAG
TCTATGCGATGTTGCACACTGCCTGTAATGCTTTGCTTGATGAAATTGTCGCAACAAAACTGTAA

Upstream 100 bases:

>100_bases
TTTTTATATCGCGAGACTATACTCGATCTTCAAATTCACGTCAAACTGGTATACTAAAGGGAGTTTTTGGCTTGATTAGA
GGTATCTAGAAGGAGTGCCC

Downstream 100 bases:

>100_bases
TAGTTAATAGTATGCCCTCACCCTAACCCCTCTCCCACTGCGGCGGACGAGGGGCGTGCCAAGCTTCATGATCACGGGAT
TCCCCCTCGCCTCGCGGGCG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVRVLFVCLGNICRSPMAEGIMRHLVEQRKLSHAIEVDSAGTSHYHIGDDPHHGTMRILRHNGISLSHRGRQFGKIDQQN
FDYLIAMDTQNRHDMQAVLGSNGAEVRLMLDYIPNGVKGRDVPDPWYTGNFEEVYAMLHTACNALLDEIVATKL

Sequences:

>Translated_154_residues
MVRVLFVCLGNICRSPMAEGIMRHLVEQRKLSHAIEVDSAGTSHYHIGDDPHHGTMRILRHNGISLSHRGRQFGKIDQQN
FDYLIAMDTQNRHDMQAVLGSNGAEVRLMLDYIPNGVKGRDVPDPWYTGNFEEVYAMLHTACNALLDEIVATKL
>Mature_154_residues
MVRVLFVCLGNICRSPMAEGIMRHLVEQRKLSHAIEVDSAGTSHYHIGDDPHHGTMRILRHNGISLSHRGRQFGKIDQQN
FDYLIAMDTQNRHDMQAVLGSNGAEVRLMLDYIPNGVKGRDVPDPWYTGNFEEVYAMLHTACNALLDEIVATKL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=150, Percent_Identity=39.3333333333333, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI6005988, Length=150, Percent_Identity=36.6666666666667, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI96304457, Length=74, Percent_Identity=48.6486486486487, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325330, Length=129, Percent_Identity=38.7596899224806, Blast_Score=104, Evalue=6e-24,
Organism=Drosophila melanogaster, GI78711846, Length=153, Percent_Identity=35.2941176470588, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI78706766, Length=152, Percent_Identity=34.8684210526316, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI78706768, Length=152, Percent_Identity=34.8684210526316, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI78706770, Length=148, Percent_Identity=32.4324324324324, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706772, Length=148, Percent_Identity=32.4324324324324, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706764, Length=132, Percent_Identity=35.6060606060606, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648069, Length=150, Percent_Identity=35.3333333333333, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17382; Mature: 17382

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVLFVCLGNICRSPMAEGIMRHLVEQRKLSHAIEVDSAGTSHYHIGDDPHHGTMRILR
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHEEHH
HNGISLSHRGRQFGKIDQQNFDYLIAMDTQNRHDMQAVLGSNGAEVRLMLDYIPNGVKGR
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCC
DVPDPWYTGNFEEVYAMLHTACNALLDEIVATKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRVLFVCLGNICRSPMAEGIMRHLVEQRKLSHAIEVDSAGTSHYHIGDDPHHGTMRILR
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHEEHH
HNGISLSHRGRQFGKIDQQNFDYLIAMDTQNRHDMQAVLGSNGAEVRLMLDYIPNGVKGR
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCC
DVPDPWYTGNFEEVYAMLHTACNALLDEIVATKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]