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The map label for this gene is yccK [H]

Identifier: 159900975

GI number: 159900975

Start: 5706363

End: 5707316

Strand: Reverse

Name: yccK [H]

Synonym: Haur_4462

Alternate gene names: 159900975

Gene position: 5707316-5706363 (Counterclockwise)

Preceding gene: 159900979

Following gene: 159900974

Centisome position: 89.93

GC content: 51.15

Gene sequence:

>954_bases
ATGGAACAACGGTCACTTGGCACACAAGGCCTCACAGTTAACCCGCTTGGCTTGGGTTGTATGGGCATGTCGGAGTTTTA
TGGCCCAACTGATGAGGCCGAATCATTAGCAACGATCGATCGCGCCTTGGAGCTTGGGGTCAATTTCTTCGATACTGCTG
ATATGTATGGGCCTTTTACCAACGAGCAATTGGTTGGCAAAGCCTTCAAAGGCCGCCGCGATCAGATCATCCTTGCGACG
AAATTTGGCATTCAACGCGAAGCCAATAATCAACGCTCGATCAATGGCCGCCCTGAATATGTTAAGGCTGCCTGCGACGC
TTCGCTGCAACGCTTAGGGGTCGATTATATTGATCTGTATTATCAGCATCGGGTCGATTCCAATGTGCCAATCGAGGAAA
CCGTTGGCGCAATGGCCGAATTGGTTCAGGCAGGCAAGGTGCGGTTTATCGGCTTATCCGAAGCCAATTCGGAAACGATT
CGCCGCGCACATCAGGTACACCCAATTAGCGCCTTGCAAACTGAATATTCGCTCTGGTCGCGCGAGCCAGAAATTGATAT
TTTGGCGACAACTCGCGAATTAGGCATTGGTTTTGTGGCCTATAGCCCGCTTGGGCGGGGCTTCTTAACTGGTCAATTTC
GGAGTGTCGATGATTTTGCCGCCGATGATTATCGCCGCTACTCGCCACGCTTCCAAGGTGAAAATTTTGGCAAAAACTTG
GCTTTGGTTGAACATATCGAGCAACTGGCCAGCCAAAAGGGCATCACGCCTGCGCAATTGGCCTTAGCCTGGGTCTTGAA
TCAAGGCGCTGATATTGTACCAATTCCAGGCACCAAGCGGCGGCGCTATCTCGAAGAAAACATGGCTGCGCTCAACGTGA
GTTTCAGTGATGCTGAACTGGCAGCAATTAACGCAGTGCTGCCAATTAATGTCGCGGTTGGCACACGCTACTAG

Upstream 100 bases:

>100_bases
TCAGGCATTACTGACAAGCTGTCGTAAACCCCTTGACTTTGAGCACGCTCAAAGGTGTAGACTGCCAATATCGGTTTGGT
GTACTCACTTGGAGGTTGGA

Downstream 100 bases:

>100_bases
ATGCCCTCACCCCCATCTCCTCTTCCAAGCTAGGTTTTTAACCATGAGTTGGGAGGGGTGCACGTCGATTAGCATGCCCT
CACCCCCTAGCCCCCTCTCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEQRSLGTQGLTVNPLGLGCMGMSEFYGPTDEAESLATIDRALELGVNFFDTADMYGPFTNEQLVGKAFKGRRDQIILAT
KFGIQREANNQRSINGRPEYVKAACDASLQRLGVDYIDLYYQHRVDSNVPIEETVGAMAELVQAGKVRFIGLSEANSETI
RRAHQVHPISALQTEYSLWSREPEIDILATTRELGIGFVAYSPLGRGFLTGQFRSVDDFAADDYRRYSPRFQGENFGKNL
ALVEHIEQLASQKGITPAQLALAWVLNQGADIVPIPGTKRRRYLEENMAALNVSFSDAELAAINAVLPINVAVGTRY

Sequences:

>Translated_317_residues
MEQRSLGTQGLTVNPLGLGCMGMSEFYGPTDEAESLATIDRALELGVNFFDTADMYGPFTNEQLVGKAFKGRRDQIILAT
KFGIQREANNQRSINGRPEYVKAACDASLQRLGVDYIDLYYQHRVDSNVPIEETVGAMAELVQAGKVRFIGLSEANSETI
RRAHQVHPISALQTEYSLWSREPEIDILATTRELGIGFVAYSPLGRGFLTGQFRSVDDFAADDYRRYSPRFQGENFGKNL
ALVEHIEQLASQKGITPAQLALAWVLNQGADIVPIPGTKRRRYLEENMAALNVSFSDAELAAINAVLPINVAVGTRY
>Mature_317_residues
MEQRSLGTQGLTVNPLGLGCMGMSEFYGPTDEAESLATIDRALELGVNFFDTADMYGPFTNEQLVGKAFKGRRDQIILAT
KFGIQREANNQRSINGRPEYVKAACDASLQRLGVDYIDLYYQHRVDSNVPIEETVGAMAELVQAGKVRFIGLSEANSETI
RRAHQVHPISALQTEYSLWSREPEIDILATTRELGIGFVAYSPLGRGFLTGQFRSVDDFAADDYRRYSPRFQGENFGKNL
ALVEHIEQLASQKGITPAQLALAWVLNQGADIVPIPGTKRRRYLEENMAALNVSFSDAELAAINAVLPINVAVGTRY

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=31.9354838709677, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=30.6748466257669, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=31.9354838709677, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=30.6501547987616, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=31.9354838709677, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI27436971, Length=307, Percent_Identity=30.2931596091205, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI223718702, Length=301, Percent_Identity=31.5614617940199, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=30.5147058823529, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41152114, Length=218, Percent_Identity=30.2752293577982, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=34.6031746031746, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=31.8452380952381, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=32.4074074074074, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=30.7692307692308, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788081, Length=300, Percent_Identity=30.3333333333333, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=31.700288184438, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17566692, Length=316, Percent_Identity=25.9493670886076, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325384, Length=331, Percent_Identity=30.8157099697885, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=26.099706744868, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=328, Percent_Identity=25.9146341463415, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=23.9344262295082, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=329, Percent_Identity=24.6200607902736, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=270, Percent_Identity=23.3333333333333, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45553081, Length=312, Percent_Identity=28.8461538461538, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281366140, Length=283, Percent_Identity=28.9752650176678, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646155, Length=321, Percent_Identity=24.6105919003115, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646159, Length=169, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24640980, Length=320, Percent_Identity=24.375, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45549126, Length=320, Percent_Identity=24.375, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24663317, Length=331, Percent_Identity=24.773413897281, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24657054, Length=322, Percent_Identity=25.776397515528, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644950, Length=334, Percent_Identity=23.9520958083832, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35044; Mature: 35044

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRSLGTQGLTVNPLGLGCMGMSEFYGPTDEAESLATIDRALELGVNFFDTADMYGPFT
CCCCCCCCCCCEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
NEQLVGKAFKGRRDQIILATKFGIQREANNQRSINGRPEYVKAACDASLQRLGVDYIDLY
CHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
YQHRVDSNVPIEETVGAMAELVQAGKVRFIGLSEANSETIRRAHQVHPISALQTEYSLWS
HHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHC
REPEIDILATTRELGIGFVAYSPLGRGFLTGQFRSVDDFAADDYRRYSPRFQGENFGKNL
CCCCEEEEEEHHHHCEEEEEECCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
ALVEHIEQLASQKGITPAQLALAWVLNQGADIVPIPGTKRRRYLEENMAALNVSFSDAEL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHEEEEECCCCHH
AAINAVLPINVAVGTRY
EEEEEEEEEEEECCCCC
>Mature Secondary Structure
MEQRSLGTQGLTVNPLGLGCMGMSEFYGPTDEAESLATIDRALELGVNFFDTADMYGPFT
CCCCCCCCCCCEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
NEQLVGKAFKGRRDQIILATKFGIQREANNQRSINGRPEYVKAACDASLQRLGVDYIDLY
CHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
YQHRVDSNVPIEETVGAMAELVQAGKVRFIGLSEANSETIRRAHQVHPISALQTEYSLWS
HHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHC
REPEIDILATTRELGIGFVAYSPLGRGFLTGQFRSVDDFAADDYRRYSPRFQGENFGKNL
CCCCEEEEEEHHHHCEEEEEECCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
ALVEHIEQLASQKGITPAQLALAWVLNQGADIVPIPGTKRRRYLEENMAALNVSFSDAEL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHEEEEECCCCHH
AAINAVLPINVAVGTRY
EEEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]