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The map label for this gene is rsbRA [H]

Identifier: 159900935

GI number: 159900935

Start: 5658405

End: 5659883

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_4422

Alternate gene names: 159900935

Gene position: 5659883-5658405 (Counterclockwise)

Preceding gene: 159900936

Following gene: 159900931

Centisome position: 89.18

GC content: 48.88

Gene sequence:

>1479_bases
ATGCTTGCTTATTGGATTAATTTGGTATTTGTGATGCTTGAAACGGCTTTGGGCACGTTTATTTTGGCCCGATCTAGCCA
TTATCGCCCAGCCCGAATCTTTTTTGGGTTAACCCTATGCTTGATAGTCATTAATAGCACGGCGCTTGCCCGTAATCTAA
CAACTGATCATGCTACCTCGTATGGGTTGGTTGGGATTGCCCTGGTGAGCCTGGGGTTGCTTTGTTGGTTGATGTTGCTT
TTGTTTGCAGCGTTGTTTATGCCACAATGGTGGGAAGGCTCACGCCCAATTCGCTCGATTTCATTGGTTTATGGCCTATC
GATTGGCTTATTAGCACTTGATTTGATTGGGCAATTTGGCTGGTTTACCACTGGGATCGAATTAGCCAATGGCAGCTATC
GGCCTATCGCTGGGCCAGCGGCGGGTTTGATGTTGGCTTTATTTAGCCTTGGGTGGTTGGTGCAGCTTGGATTGTTAGGC
ATGGCATTTTGGAGACAACCAGCAACCCGCCGCTCCATTAGTTGGTTGGCTTTTGCAATTCTCTTTTCAGCATTGACCAA
CTCGGTATTGGGGATTGTCAAGCTTGAGCCAAGTGGCCAGTTGGCAAGTGTGCTACAAACGTTGCCCTTGGTTTTAAGTT
TGACCTACATTGTTTTGCGTGGCAGTTTGTTTCAGACCAAACAAGTAGCGGTGCAGCAGGCTTTGCAAACCATGAGCGAA
GCGATGGTGGTCGTTGATCGCGAAGGAATGATTGTTTATCTCAATAATGCGGCCCACCAGCTTGGTTTGCAAACTCAGCA
ACCACTTCAACAGGCATTTCAAACGATTGGAGTTGCAGTTGATGATGTTGCGGCTTTGGCTAAAGCATTAGCGCAGCCGC
AAATCCAAGCTTTTACTCAAACGCTGGCCTTGGGCAACCCTTTGCGCTTGCTAGAAAATGCAGTATCACCAATTTTGGAT
AGCGCTGGACAGAGCCAAGGTACGATGTTGTTCATTCGGGATATTACCGAGTTGGAGCGGCACACGGCTTTGTTGGAGCA
GGAACGGCGGCGCTTGAGCGTAATGGTAGAACAACTTGAGCAGGAACAAATCCAACGTAATCAATTGACTCAAGCAGTTC
AGGCGCTCTCATTTCCAACGATTCCGGTTTTGCCGGGCGTGCTGGTTCTACCCCTGATCGGGGTACTTGATCAGCAGCGA
ATTATTGAATGTCAACGGGTTTTGATGGAATCATTGAATCAGCAGCCAGTTCAACGTTTGCTGATAGATTTGACCGGAGT
TCAATTGATCGATGCTGAAGGTGCAATTGGCATGCAGCGAATGTTGCGGGCCGCCTATTTGCTTGGTGCTCAAACAACAT
TAATCGGGGTACGACCTGAGGTCGCTCAAGCCTTGGTTGGAATGGGCGCTGATTTGCAGCATGTCGCGACCGCCGCAACC
CTGCAAGCTGCGGTCGGCCAAATTATCGCCAAAGGCTAG

Upstream 100 bases:

>100_bases
GGCAAAATCTACCTCAATAGGCAGCTACAAAGGATGGGCAAGCTCTAGACGATCCGCTATCATACAGTTGTTACACCAAT
CAACCTAGGATCAAAAATAG

Downstream 100 bases:

>100_bases
GCCACGCCAAACCAAAAAATGACGTGGCTCAGGCAATTAATGTTTAGCGCGGGCGAATCGCTAGGCCTTGCAATTCGAGC
GCATATTCAACTCCGGCTTG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLAYWINLVFVMLETALGTFILARSSHYRPARIFFGLTLCLIVINSTALARNLTTDHATSYGLVGIALVSLGLLCWLMLL
LFAALFMPQWWEGSRPIRSISLVYGLSIGLLALDLIGQFGWFTTGIELANGSYRPIAGPAAGLMLALFSLGWLVQLGLLG
MAFWRQPATRRSISWLAFAILFSALTNSVLGIVKLEPSGQLASVLQTLPLVLSLTYIVLRGSLFQTKQVAVQQALQTMSE
AMVVVDREGMIVYLNNAAHQLGLQTQQPLQQAFQTIGVAVDDVAALAKALAQPQIQAFTQTLALGNPLRLLENAVSPILD
SAGQSQGTMLFIRDITELERHTALLEQERRRLSVMVEQLEQEQIQRNQLTQAVQALSFPTIPVLPGVLVLPLIGVLDQQR
IIECQRVLMESLNQQPVQRLLIDLTGVQLIDAEGAIGMQRMLRAAYLLGAQTTLIGVRPEVAQALVGMGADLQHVATAAT
LQAAVGQIIAKG

Sequences:

>Translated_492_residues
MLAYWINLVFVMLETALGTFILARSSHYRPARIFFGLTLCLIVINSTALARNLTTDHATSYGLVGIALVSLGLLCWLMLL
LFAALFMPQWWEGSRPIRSISLVYGLSIGLLALDLIGQFGWFTTGIELANGSYRPIAGPAAGLMLALFSLGWLVQLGLLG
MAFWRQPATRRSISWLAFAILFSALTNSVLGIVKLEPSGQLASVLQTLPLVLSLTYIVLRGSLFQTKQVAVQQALQTMSE
AMVVVDREGMIVYLNNAAHQLGLQTQQPLQQAFQTIGVAVDDVAALAKALAQPQIQAFTQTLALGNPLRLLENAVSPILD
SAGQSQGTMLFIRDITELERHTALLEQERRRLSVMVEQLEQEQIQRNQLTQAVQALSFPTIPVLPGVLVLPLIGVLDQQR
IIECQRVLMESLNQQPVQRLLIDLTGVQLIDAEGAIGMQRMLRAAYLLGAQTTLIGVRPEVAQALVGMGADLQHVATAAT
LQAAVGQIIAKG
>Mature_492_residues
MLAYWINLVFVMLETALGTFILARSSHYRPARIFFGLTLCLIVINSTALARNLTTDHATSYGLVGIALVSLGLLCWLMLL
LFAALFMPQWWEGSRPIRSISLVYGLSIGLLALDLIGQFGWFTTGIELANGSYRPIAGPAAGLMLALFSLGWLVQLGLLG
MAFWRQPATRRSISWLAFAILFSALTNSVLGIVKLEPSGQLASVLQTLPLVLSLTYIVLRGSLFQTKQVAVQQALQTMSE
AMVVVDREGMIVYLNNAAHQLGLQTQQPLQQAFQTIGVAVDDVAALAKALAQPQIQAFTQTLALGNPLRLLENAVSPILD
SAGQSQGTMLFIRDITELERHTALLEQERRRLSVMVEQLEQEQIQRNQLTQAVQALSFPTIPVLPGVLVLPLIGVLDQQR
IIECQRVLMESLNQQPVQRLLIDLTGVQLIDAEGAIGMQRMLRAAYLLGAQTTLIGVRPEVAQALVGMGADLQHVATAAT
LQAAVGQIIAKG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 53519; Mature: 53519

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYWINLVFVMLETALGTFILARSSHYRPARIFFGLTLCLIVINSTALARNLTTDHATS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHH
YGLVGIALVSLGLLCWLMLLLFAALFMPQWWEGSRPIRSISLVYGLSIGLLALDLIGQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WFTTGIELANGSYRPIAGPAAGLMLALFSLGWLVQLGLLGMAFWRQPATRRSISWLAFAI
HHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LFSALTNSVLGIVKLEPSGQLASVLQTLPLVLSLTYIVLRGSLFQTKQVAVQQALQTMSE
HHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AMVVVDREGMIVYLNNAAHQLGLQTQQPLQQAFQTIGVAVDDVAALAKALAQPQIQAFTQ
HEEEEECCCEEEEECCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHH
TLALGNPLRLLENAVSPILDSAGQSQGTMLFIRDITELERHTALLEQERRRLSVMVEQLE
HHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEQIQRNQLTQAVQALSFPTIPVLPGVLVLPLIGVLDQQRIIECQRVLMESLNQQPVQRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LIDLTGVQLIDAEGAIGMQRMLRAAYLLGAQTTLIGVRPEVAQALVGMGADLQHVATAAT
HHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHCCCCHHHHHHHHH
LQAAVGQIIAKG
HHHHHHHHHCCC
>Mature Secondary Structure
MLAYWINLVFVMLETALGTFILARSSHYRPARIFFGLTLCLIVINSTALARNLTTDHATS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHH
YGLVGIALVSLGLLCWLMLLLFAALFMPQWWEGSRPIRSISLVYGLSIGLLALDLIGQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WFTTGIELANGSYRPIAGPAAGLMLALFSLGWLVQLGLLGMAFWRQPATRRSISWLAFAI
HHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LFSALTNSVLGIVKLEPSGQLASVLQTLPLVLSLTYIVLRGSLFQTKQVAVQQALQTMSE
HHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AMVVVDREGMIVYLNNAAHQLGLQTQQPLQQAFQTIGVAVDDVAALAKALAQPQIQAFTQ
HEEEEECCCEEEEECCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHH
TLALGNPLRLLENAVSPILDSAGQSQGTMLFIRDITELERHTALLEQERRRLSVMVEQLE
HHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEQIQRNQLTQAVQALSFPTIPVLPGVLVLPLIGVLDQQRIIECQRVLMESLNQQPVQRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LIDLTGVQLIDAEGAIGMQRMLRAAYLLGAQTTLIGVRPEVAQALVGMGADLQHVATAAT
HHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHCCCCHHHHHHHHH
LQAAVGQIIAKG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]