Click here to switch to the map view.

The map label for this gene is fadN [H]

Identifier: 159900907

GI number: 159900907

Start: 5613624

End: 5616038

Strand: Reverse

Name: fadN [H]

Synonym: Haur_4394

Alternate gene names: 159900907

Gene position: 5616038-5613624 (Counterclockwise)

Preceding gene: 159900908

Following gene: 159900906

Centisome position: 88.49

GC content: 52.3

Gene sequence:

>2415_bases
ATGACGTACCGCATTCAACGTGCAGTGGTAATTGGCTCAGGCACAATGGGTGGTGGCATCGCCGCTCATCTAGCCAATGC
TGGCGTGCGCACCGTGTTGTTGGATATTGTGCCAAGCACGCTCACGCCTGAGGAAGAGGCCAAAGGGCTTTCGTTGCAAA
GCAAAGCCGTGCGCAATCGAATTGTGCAAACTGGCTGGGATCGCGTGGTCAAGAGCAGCCCCGCCGCGCTCATGAACAAA
AAAGCTGGCGAATTGGTGCAGCTTGGCAATCTCGAAGACGATTTCACAGTTGTCAGCGAAGCTGATTGGGTAATTGAAGT
TATCGTTGAAAAACTCGAACCCAAGCAACAACTTATGGCGCGAATCGATGAAATTCGCAAAGCTGGCAGCATTATTTCAT
CGAACACCAGCGGGATTCCAATTCACAAAATTGCTGAAGGTCGCTCCGACGATTTCAAAAAGCACTTCCTTGGAACCCAC
TTCTTCAACCCACCCCGCTACCTCAAATTACTCGAAGTGATTCCAACGCCAGATACCGATCAGGCGATTATTGACTATAT
TCGCAGTTTTGGTCAAGAACGCTTGGGTAAAGGCGTGGTGATTGCCAAAGATACGCCGAACTTTATCGCCAACCGCATCG
GCACCTTTGGCGGCGCATACGCCATGAAATATATCGTCGATAACGGCTACACGATTGAAGAAGTCGATGCCTTGACCGGA
ACCTTAATTGGCAATCCCAAATCGGGAACCTTCCGGCTTGGCGATTTGGTGGGGATTGATGTGATGGTTGGGGTGGCCCA
CAACCTCTACAATCTCGTGCCCAACGACGAATCACGCGACGCGCTGCTGGCTCCAGCTCCCGTGCAAGGCTTGCTAGAAC
GGGGCTGGCTCGGCCAAAAATCAGGCCAAGGTTTCTACAAAACCGTCAAAGGCGCAAATGGCAAGGAATTTTGGGTGCTC
GATTGGGAAACTGGCGAACATCGCGCCCCACGAGAAGTTGATTTGCCGATCATCAAGCAAGCCAAAAAGCAGGGCAACTT
GGCGGCTCGCCTGCGTTTCTTGGTCAACCAAAGCCAAGATCGTGGCGGCAAACTGATCGCCGATACCTTGTTGCCATCGT
TGGCCTATGCTGCTCGCCGCGTGCCAGAAATTAGCGACCATCTGTACGATGTTGATAATGCTTTGCGCTGGGGCTTTGCC
AAGGAGATGGGGCCATTTGAAATGTGGGATGCGATTGGCCTCGCCGATGGCGTGAAGCTAATGCAAGATCGCGATATTCA
GGTGGCCGATTGGGTTTTGGCATTACTCGAAAAAGGCCATAACTCGTTCTATCAAACGGTCGATGGCGCGAAACAAGCCT
ATAGCCCAGTCACTGGCGAATACGAAGCCGTGCCAAGCTCCGACCTGAAAATCGACCTTGACGAGTTGCGCAGCACAGGC
AAAGAAGTTGCCCGCAACGATTCAGCCAGCCTGCTCGATTTAGGCGATGGCGTATTGTGCTTCGAATTCCATTCCAAGAT
GAATGCGCTGGATAGCGAAATCACCGAAATGGGCTTCAAAGCCTTGGAATTGCTCAAAGACGATCGCTGGACAGGTATGG
TCGTTGGCAACCAAGGCTCAGATTTCTGCATCGGTGCCAATATCTTTATGTTGATGATGGCTGCTCAAAACGATCAATTC
GACCAGCTTGAGCAGATGTTGAAAACTTCGCACGACTTGATGCAAGGTATGCGCTTCTCACCCAAACCAATTGTCACCGC
ACCATTCGGGCGCGTGCTCGGTGGTGGCGCTGAAGTTTCAATGCACGGCTCGCGCATGTGTATCGCCGCTGAAACCTATA
TGGGCTTGGTCGAAGTTGGGGTTGGCTTGATTCCTGGGGCTGGTGGGGTCAAAGAATTTGTGCGCCGGATCATTACTCCA
GCCATCAAACTGGCTCCCGAAAGCGATCCAACGCCATACTTGCAACGAGTATTTGAGCAAATTGGGATGGCCAAAGTTGG
CACCAGCGCCTTTGAAGCTCGCGATCAAGGCTTTGTCACCGAAGCTGATCGGATTGTGATGAATGCTGATGAGTTGCTAG
GCCGTGCCAAGCAGTTTGTGCTTGATCTGGCAGCGGCTGGCTTTACGCCGCCCGCCCGCGAAAAACTCTACGCTGCTGGC
CGCGATGGCTTGGCTGCAATGCGGGTTGGCGTGTGGATGATGCAACAAGGCGGCTATATCTCCGAATACGATGCGTTTAT
CGGCAACAAACTGGCTTATGCGATCGCTGGCGGCGACCTCAGCAGCCCACAATGGGTCGATGAAGAGCATTTCTTGGCGA
TGGAGCGCGAAGTATTCTTGGCACTTTGCCGCGAACCAAAGACCATGGAACGCATTATGTTTATGTTGCAAAACAACAAG
CCATTGCGGAATTAG

Upstream 100 bases:

>100_bases
TTTCCTAACCTGTAATCAGCCACTAATCGCTGCAAAACCCTCGCTGATTACAACCGATTGTTGATAAAAATCGCTTCCAA
CCAGAAAGAAAGGTGGTTCA

Downstream 100 bases:

>100_bases
AAGGATGATGGGTCAGGGCAAGAAAGCGCATTCCCTCACCCCCTAGCCCCCTCTCCCGCCCAGCAGGCGAGGGGGAATAC
CTCCAGCATGAACCGTGGAA

Product: NAD-binding 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 804; Mature: 803

Protein sequence:

>804_residues
MTYRIQRAVVIGSGTMGGGIAAHLANAGVRTVLLDIVPSTLTPEEEAKGLSLQSKAVRNRIVQTGWDRVVKSSPAALMNK
KAGELVQLGNLEDDFTVVSEADWVIEVIVEKLEPKQQLMARIDEIRKAGSIISSNTSGIPIHKIAEGRSDDFKKHFLGTH
FFNPPRYLKLLEVIPTPDTDQAIIDYIRSFGQERLGKGVVIAKDTPNFIANRIGTFGGAYAMKYIVDNGYTIEEVDALTG
TLIGNPKSGTFRLGDLVGIDVMVGVAHNLYNLVPNDESRDALLAPAPVQGLLERGWLGQKSGQGFYKTVKGANGKEFWVL
DWETGEHRAPREVDLPIIKQAKKQGNLAARLRFLVNQSQDRGGKLIADTLLPSLAYAARRVPEISDHLYDVDNALRWGFA
KEMGPFEMWDAIGLADGVKLMQDRDIQVADWVLALLEKGHNSFYQTVDGAKQAYSPVTGEYEAVPSSDLKIDLDELRSTG
KEVARNDSASLLDLGDGVLCFEFHSKMNALDSEITEMGFKALELLKDDRWTGMVVGNQGSDFCIGANIFMLMMAAQNDQF
DQLEQMLKTSHDLMQGMRFSPKPIVTAPFGRVLGGGAEVSMHGSRMCIAAETYMGLVEVGVGLIPGAGGVKEFVRRIITP
AIKLAPESDPTPYLQRVFEQIGMAKVGTSAFEARDQGFVTEADRIVMNADELLGRAKQFVLDLAAAGFTPPAREKLYAAG
RDGLAAMRVGVWMMQQGGYISEYDAFIGNKLAYAIAGGDLSSPQWVDEEHFLAMEREVFLALCREPKTMERIMFMLQNNK
PLRN

Sequences:

>Translated_804_residues
MTYRIQRAVVIGSGTMGGGIAAHLANAGVRTVLLDIVPSTLTPEEEAKGLSLQSKAVRNRIVQTGWDRVVKSSPAALMNK
KAGELVQLGNLEDDFTVVSEADWVIEVIVEKLEPKQQLMARIDEIRKAGSIISSNTSGIPIHKIAEGRSDDFKKHFLGTH
FFNPPRYLKLLEVIPTPDTDQAIIDYIRSFGQERLGKGVVIAKDTPNFIANRIGTFGGAYAMKYIVDNGYTIEEVDALTG
TLIGNPKSGTFRLGDLVGIDVMVGVAHNLYNLVPNDESRDALLAPAPVQGLLERGWLGQKSGQGFYKTVKGANGKEFWVL
DWETGEHRAPREVDLPIIKQAKKQGNLAARLRFLVNQSQDRGGKLIADTLLPSLAYAARRVPEISDHLYDVDNALRWGFA
KEMGPFEMWDAIGLADGVKLMQDRDIQVADWVLALLEKGHNSFYQTVDGAKQAYSPVTGEYEAVPSSDLKIDLDELRSTG
KEVARNDSASLLDLGDGVLCFEFHSKMNALDSEITEMGFKALELLKDDRWTGMVVGNQGSDFCIGANIFMLMMAAQNDQF
DQLEQMLKTSHDLMQGMRFSPKPIVTAPFGRVLGGGAEVSMHGSRMCIAAETYMGLVEVGVGLIPGAGGVKEFVRRIITP
AIKLAPESDPTPYLQRVFEQIGMAKVGTSAFEARDQGFVTEADRIVMNADELLGRAKQFVLDLAAAGFTPPAREKLYAAG
RDGLAAMRVGVWMMQQGGYISEYDAFIGNKLAYAIAGGDLSSPQWVDEEHFLAMEREVFLALCREPKTMERIMFMLQNNK
PLRN
>Mature_803_residues
TYRIQRAVVIGSGTMGGGIAAHLANAGVRTVLLDIVPSTLTPEEEAKGLSLQSKAVRNRIVQTGWDRVVKSSPAALMNKK
AGELVQLGNLEDDFTVVSEADWVIEVIVEKLEPKQQLMARIDEIRKAGSIISSNTSGIPIHKIAEGRSDDFKKHFLGTHF
FNPPRYLKLLEVIPTPDTDQAIIDYIRSFGQERLGKGVVIAKDTPNFIANRIGTFGGAYAMKYIVDNGYTIEEVDALTGT
LIGNPKSGTFRLGDLVGIDVMVGVAHNLYNLVPNDESRDALLAPAPVQGLLERGWLGQKSGQGFYKTVKGANGKEFWVLD
WETGEHRAPREVDLPIIKQAKKQGNLAARLRFLVNQSQDRGGKLIADTLLPSLAYAARRVPEISDHLYDVDNALRWGFAK
EMGPFEMWDAIGLADGVKLMQDRDIQVADWVLALLEKGHNSFYQTVDGAKQAYSPVTGEYEAVPSSDLKIDLDELRSTGK
EVARNDSASLLDLGDGVLCFEFHSKMNALDSEITEMGFKALELLKDDRWTGMVVGNQGSDFCIGANIFMLMMAAQNDQFD
QLEQMLKTSHDLMQGMRFSPKPIVTAPFGRVLGGGAEVSMHGSRMCIAAETYMGLVEVGVGLIPGAGGVKEFVRRIITPA
IKLAPESDPTPYLQRVFEQIGMAKVGTSAFEARDQGFVTEADRIVMNADELLGRAKQFVLDLAAAGFTPPAREKLYAAGR
DGLAAMRVGVWMMQQGGYISEYDAFIGNKLAYAIAGGDLSSPQWVDEEHFLAMEREVFLALCREPKTMERIMFMLQNNKP
LRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=310, Percent_Identity=31.2903225806452, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI296179427, Length=327, Percent_Identity=29.9694189602446, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI20127408, Length=313, Percent_Identity=27.4760383386581, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI261878539, Length=307, Percent_Identity=28.0130293159609, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI68989263, Length=307, Percent_Identity=28.0130293159609, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1787661, Length=307, Percent_Identity=30.2931596091205, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790281, Length=222, Percent_Identity=25.6756756756757, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788682, Length=333, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17549919, Length=314, Percent_Identity=30.2547770700637, Blast_Score=123, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17553560, Length=305, Percent_Identity=32.1311475409836, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17508953, Length=313, Percent_Identity=29.7124600638978, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17508951, Length=313, Percent_Identity=29.7124600638978, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25144276, Length=313, Percent_Identity=29.7124600638978, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17563036, Length=305, Percent_Identity=29.5081967213115, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=313, Percent_Identity=28.1150159744409, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71985930, Length=310, Percent_Identity=24.8387096774194, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19921000, Length=302, Percent_Identity=28.476821192053, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24583077, Length=302, Percent_Identity=28.476821192053, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24583079, Length=302, Percent_Identity=28.476821192053, Blast_Score=90, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 88291; Mature: 88160

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRIQRAVVIGSGTMGGGIAAHLANAGVRTVLLDIVPSTLTPEEEAKGLSLQSKAVRNR
CCEEEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHH
IVQTGWDRVVKSSPAALMNKKAGELVQLGNLEDDFTVVSEADWVIEVIVEKLEPKQQLMA
HHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHCCCHHHHHH
RIDEIRKAGSIISSNTSGIPIHKIAEGRSDDFKKHFLGTHFFNPPRYLKLLEVIPTPDTD
HHHHHHHHCCHHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCH
QAIIDYIRSFGQERLGKGVVIAKDTPNFIANRIGTFGGAYAMKYIVDNGYTIEEVDALTG
HHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
TLIGNPKSGTFRLGDLVGIDVMVGVAHNLYNLVPNDESRDALLAPAPVQGLLERGWLGQK
HEECCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHCCCCCCC
SGQGFYKTVKGANGKEFWVLDWETGEHRAPREVDLPIIKQAKKQGNLAARLRFLVNQSQD
CCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCC
RGGKLIADTLLPSLAYAARRVPEISDHLYDVDNALRWGFAKEMGPFEMWDAIGLADGVKL
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MQDRDIQVADWVLALLEKGHNSFYQTVDGAKQAYSPVTGEYEAVPSSDLKIDLDELRSTG
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHH
KEVARNDSASLLDLGDGVLCFEFHSKMNALDSEITEMGFKALELLKDDRWTGMVVGNQGS
HHHHCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
DFCIGANIFMLMMAAQNDQFDQLEQMLKTSHDLMQGMRFSPKPIVTAPFGRVLGGGAEVS
CEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHCCCCEEE
MHGSRMCIAAETYMGLVEVGVGLIPGAGGVKEFVRRIITPAIKLAPESDPTPYLQRVFEQ
ECCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHEECCCCCCCHHHHHHHHH
IGMAKVGTSAFEARDQGFVTEADRIVMNADELLGRAKQFVLDLAAAGFTPPAREKLYAAG
HCCHHCCCHHHHHCCCCCEECHHHHEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
RDGLAAMRVGVWMMQQGGYISEYDAFIGNKLAYAIAGGDLSSPQWVDEEHFLAMEREVFL
CCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ALCREPKTMERIMFMLQNNKPLRN
HHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TYRIQRAVVIGSGTMGGGIAAHLANAGVRTVLLDIVPSTLTPEEEAKGLSLQSKAVRNR
CEEEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHH
IVQTGWDRVVKSSPAALMNKKAGELVQLGNLEDDFTVVSEADWVIEVIVEKLEPKQQLMA
HHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHCCCHHHHHH
RIDEIRKAGSIISSNTSGIPIHKIAEGRSDDFKKHFLGTHFFNPPRYLKLLEVIPTPDTD
HHHHHHHHCCHHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCH
QAIIDYIRSFGQERLGKGVVIAKDTPNFIANRIGTFGGAYAMKYIVDNGYTIEEVDALTG
HHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
TLIGNPKSGTFRLGDLVGIDVMVGVAHNLYNLVPNDESRDALLAPAPVQGLLERGWLGQK
HEECCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHCCCCCCC
SGQGFYKTVKGANGKEFWVLDWETGEHRAPREVDLPIIKQAKKQGNLAARLRFLVNQSQD
CCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCC
RGGKLIADTLLPSLAYAARRVPEISDHLYDVDNALRWGFAKEMGPFEMWDAIGLADGVKL
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MQDRDIQVADWVLALLEKGHNSFYQTVDGAKQAYSPVTGEYEAVPSSDLKIDLDELRSTG
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHH
KEVARNDSASLLDLGDGVLCFEFHSKMNALDSEITEMGFKALELLKDDRWTGMVVGNQGS
HHHHCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
DFCIGANIFMLMMAAQNDQFDQLEQMLKTSHDLMQGMRFSPKPIVTAPFGRVLGGGAEVS
CEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHCCCCEEE
MHGSRMCIAAETYMGLVEVGVGLIPGAGGVKEFVRRIITPAIKLAPESDPTPYLQRVFEQ
ECCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHEECCCCCCCHHHHHHHHH
IGMAKVGTSAFEARDQGFVTEADRIVMNADELLGRAKQFVLDLAAAGFTPPAREKLYAAG
HCCHHCCCHHHHHCCCCCEECHHHHEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
RDGLAAMRVGVWMMQQGGYISEYDAFIGNKLAYAIAGGDLSSPQWVDEEHFLAMEREVFL
CCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ALCREPKTMERIMFMLQNNKPLRN
HHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]