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The map label for this gene is htpG [H]

Identifier: 159900889

GI number: 159900889

Start: 5590761

End: 5593277

Strand: Reverse

Name: htpG [H]

Synonym: Haur_4376

Alternate gene names: 159900889

Gene position: 5593277-5590761 (Counterclockwise)

Preceding gene: 159900890

Following gene: 159900886

Centisome position: 88.13

GC content: 50.74

Gene sequence:

>2517_bases
ATGCAACGACCACATGGAATCCGCCAAGGTCAAATGACGATTAATGTGCCTGGAGTGATTCGGACGCTTGGCGAAAGTTT
ATATGCCGACCCGCATGTGGCGATTCGCGAATTGCTGCAAAATGCCCACGATACCTGCCTTGTGCGCCAAGCAGATGATC
CAAATGCGCCATTGCCTGAAATTCATGTGCGCTATGATCCTTTTGGCCGTAGCTTGACGATCGAAGATAACGGCGCAGGT
ATGACCGAGGCTGAAGTTGAGCAATTTCTCTCGGTGATTGGGGCTAGCAACACCGATGCTGTGCGTTCGCGGCTTGAGGC
GATCGGCGAGCGTAGTTTGGCCGAACGCTTGATCGGGCGCTTTGGCTTGGGCATGCTGGCAGCCTTTATCATCGGCGAAC
GGATTGAGTTTGTTACCCGTTCGTTTCGCAGCGAAGGCGAAGCGGCAGTTTGGTGGGAATGTAGCGGCGAGCAATCCTAT
CGGATGGGCCAAACCACCCGCCCGACTGCTGGTACAACCGTCACCGTGGCGATCAAGCCAAGCCAAGTCCATTTGCTACG
TGAAGATGAGCTGAGTCGTTTGATTCGGCTGTTTGCTGATTTGCTGAGTGTGCCGATTTACCTTGACCCTTCGCCACGCC
CAGTCAATGTGATGCAAGCGCCATGGCATAGCGAAGCCAGTGAAAGCGAGTATATTCGCTATTTGAACGAGCTATATCCT
AGTGAATCAGTATTGGCGGTGATTCCGCTGAATATTGAGGAAGATGATGGCGCGTTTAAACTCGGTGGCGTGCTGTTTAT
TCCCAAGCAGTTGTATTTGAATGTCCGTGAACATGGCGATTTAATTATCTATGTGCGGCGGATGTTTGTCTGTCGTGGTG
AGCGCAGCCTACTGCCAGAGTGGGCTAAATTCGTCAAAGGTGTGGTTGAAAGCCCAAATCTGCGCGAAACAACCTCACGC
GAGGCTTTGCGTCGCGATGAATATTTCGAGCGAGTGCAACGTACTTTGGGCCAAGTAATTTTAAATTATCTTGAACAACT
GGCGCTCAATGATCAGCGTTTATTCCGCGAGGTTGTTACCCAACACAACCGCGTAATCAAATCGTGGGCGTTAATTTCCG
ATGAATTATTTATTCGGATCAAAGATATTGTGTTGTTTGATACGGATGCAGGGCGCATGAATTTGCCACGCTATTTTGAG
CAATCGCAGCTTTCGCGTAGTGGCATCAACAACGACGACCCACATCAACACTTGTTATTCTATTTCACTACGCCAGGCGG
GATTGGCCAACATGCGGTGTTGTTTGCGGCCAAGGGCTTGCGGGTGATTGACGGCCAATATTTTCCCGATGAGCCATTTT
TGCGCCGTTACGCTGAATTAACGCCCAATATTGGCCTACGCCGTTTGGATGTTGGTGGCGATTTCATTTTCGAAGCCATG
CCCAACAAAGATCAACGTTGGTTGGAGCTTGAGGAGCGCTACGCCGAAATGGGTGTTGAAGCCCAAGTTGCCCAATATTT
GCCCGAATCGATTCCAGCGGTCTTGATCTTTTCTGAGAATTCCGAAACGAACGAGCAAGTTGACACCCTGCTGGCTGACC
CAAATTTGAGCCCATCGATTAAGCAACTGCTGCGGGCGATGCTCGATGAGCGCAAAGCTGAGCGCAAACATACCGCCAGC
AAAGGCATGCTCTATTTAAATGCTCGTAACGCGGTGATTAACCAAGTGGCGCAATTAAACCATTATGCCGACCCGCAAAT
GCGCGATGTGCTGATTTTTCTCTACAACAATGCGCTGATGTTGAGTGCCCAAGGTGCGCAGCGGATCGTCAAGCCTGAGC
ATGCCAAGCAAATTTTCGATGCCAACAACCGCGTTGCTAGCGCCCTGATGAATGCAATCACGGGCACAACCAATGCTGTT
GATGTGCCGCAAGCCACCGTTGCACCCTACGCTGTGTTGATCAACACCTTGGGTAATAACCAAGTTAACCAAGAATTGCG
CTATGTGCTGGAAAGTGCCCCCTTCTTTTTGCGAATCGTTGGCATCGATGCAGCAATCTCGTTGACTGAACATAGTTTGC
AGAGCTTGCAGCAGGCCGCCTGTATTGTGATTGATGCCAGCGAGCCAGCCCAAACTAGTTTGTTGGCGTTGGGGGCAGTT
TGGGCGATCGCGCCGCATGTGCCGATTATCGCTTTGCGTTCAGCTGAAACCGAGCCATTGGCGATTCCCATAATTGATGT
AGTTTATGATTTGGGGGTGCGAGGCGAGGCATTGCAGCGGGCGTTGCAGGAATTAAATCTTGCTCAAGCCGCCAGTCGCC
TAACTGCTGCCGATTTTCTGCGCTATGAATTTGTGAGCGAACGCTTAGCTCAAGCCTTGGCCGAGCAATTTAACAGCATC
GATCAATTGCTGCGTGCCGATCCAGCTGAGGTCAGCAATTTGCTGGGAGTTCGTTTAGCACCTTTGGGCTTGATTGAGGA
ATTACAACGAGCTTTAGAAGAAGATCGCGGACATTAG

Upstream 100 bases:

>100_bases
TTCCAGCGGGGTCGAACTCACGCCCGAACTGGGTGAGGCGGTGCAAAAAGCCCAAACTTCGCTGCTCGAACTGGCACTGG
CTCAACGCTAAGGAGTTGTT

Downstream 100 bases:

>100_bases
ATCCGACGGAGTACCACGACGGTCATATCATCTTGGTATTGGCCGTCGCTCCAGCGATTGGCGGCGTTCATAATTTCGCT
CACCAACTGCGAGGCCGGAC

Product: HSP90 family molecular chaperone-like protein

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 838; Mature: 838

Protein sequence:

>838_residues
MQRPHGIRQGQMTINVPGVIRTLGESLYADPHVAIRELLQNAHDTCLVRQADDPNAPLPEIHVRYDPFGRSLTIEDNGAG
MTEAEVEQFLSVIGASNTDAVRSRLEAIGERSLAERLIGRFGLGMLAAFIIGERIEFVTRSFRSEGEAAVWWECSGEQSY
RMGQTTRPTAGTTVTVAIKPSQVHLLREDELSRLIRLFADLLSVPIYLDPSPRPVNVMQAPWHSEASESEYIRYLNELYP
SESVLAVIPLNIEEDDGAFKLGGVLFIPKQLYLNVREHGDLIIYVRRMFVCRGERSLLPEWAKFVKGVVESPNLRETTSR
EALRRDEYFERVQRTLGQVILNYLEQLALNDQRLFREVVTQHNRVIKSWALISDELFIRIKDIVLFDTDAGRMNLPRYFE
QSQLSRSGINNDDPHQHLLFYFTTPGGIGQHAVLFAAKGLRVIDGQYFPDEPFLRRYAELTPNIGLRRLDVGGDFIFEAM
PNKDQRWLELEERYAEMGVEAQVAQYLPESIPAVLIFSENSETNEQVDTLLADPNLSPSIKQLLRAMLDERKAERKHTAS
KGMLYLNARNAVINQVAQLNHYADPQMRDVLIFLYNNALMLSAQGAQRIVKPEHAKQIFDANNRVASALMNAITGTTNAV
DVPQATVAPYAVLINTLGNNQVNQELRYVLESAPFFLRIVGIDAAISLTEHSLQSLQQAACIVIDASEPAQTSLLALGAV
WAIAPHVPIIALRSAETEPLAIPIIDVVYDLGVRGEALQRALQELNLAQAASRLTAADFLRYEFVSERLAQALAEQFNSI
DQLLRADPAEVSNLLGVRLAPLGLIEELQRALEEDRGH

Sequences:

>Translated_838_residues
MQRPHGIRQGQMTINVPGVIRTLGESLYADPHVAIRELLQNAHDTCLVRQADDPNAPLPEIHVRYDPFGRSLTIEDNGAG
MTEAEVEQFLSVIGASNTDAVRSRLEAIGERSLAERLIGRFGLGMLAAFIIGERIEFVTRSFRSEGEAAVWWECSGEQSY
RMGQTTRPTAGTTVTVAIKPSQVHLLREDELSRLIRLFADLLSVPIYLDPSPRPVNVMQAPWHSEASESEYIRYLNELYP
SESVLAVIPLNIEEDDGAFKLGGVLFIPKQLYLNVREHGDLIIYVRRMFVCRGERSLLPEWAKFVKGVVESPNLRETTSR
EALRRDEYFERVQRTLGQVILNYLEQLALNDQRLFREVVTQHNRVIKSWALISDELFIRIKDIVLFDTDAGRMNLPRYFE
QSQLSRSGINNDDPHQHLLFYFTTPGGIGQHAVLFAAKGLRVIDGQYFPDEPFLRRYAELTPNIGLRRLDVGGDFIFEAM
PNKDQRWLELEERYAEMGVEAQVAQYLPESIPAVLIFSENSETNEQVDTLLADPNLSPSIKQLLRAMLDERKAERKHTAS
KGMLYLNARNAVINQVAQLNHYADPQMRDVLIFLYNNALMLSAQGAQRIVKPEHAKQIFDANNRVASALMNAITGTTNAV
DVPQATVAPYAVLINTLGNNQVNQELRYVLESAPFFLRIVGIDAAISLTEHSLQSLQQAACIVIDASEPAQTSLLALGAV
WAIAPHVPIIALRSAETEPLAIPIIDVVYDLGVRGEALQRALQELNLAQAASRLTAADFLRYEFVSERLAQALAEQFNSI
DQLLRADPAEVSNLLGVRLAPLGLIEELQRALEEDRGH
>Mature_838_residues
MQRPHGIRQGQMTINVPGVIRTLGESLYADPHVAIRELLQNAHDTCLVRQADDPNAPLPEIHVRYDPFGRSLTIEDNGAG
MTEAEVEQFLSVIGASNTDAVRSRLEAIGERSLAERLIGRFGLGMLAAFIIGERIEFVTRSFRSEGEAAVWWECSGEQSY
RMGQTTRPTAGTTVTVAIKPSQVHLLREDELSRLIRLFADLLSVPIYLDPSPRPVNVMQAPWHSEASESEYIRYLNELYP
SESVLAVIPLNIEEDDGAFKLGGVLFIPKQLYLNVREHGDLIIYVRRMFVCRGERSLLPEWAKFVKGVVESPNLRETTSR
EALRRDEYFERVQRTLGQVILNYLEQLALNDQRLFREVVTQHNRVIKSWALISDELFIRIKDIVLFDTDAGRMNLPRYFE
QSQLSRSGINNDDPHQHLLFYFTTPGGIGQHAVLFAAKGLRVIDGQYFPDEPFLRRYAELTPNIGLRRLDVGGDFIFEAM
PNKDQRWLELEERYAEMGVEAQVAQYLPESIPAVLIFSENSETNEQVDTLLADPNLSPSIKQLLRAMLDERKAERKHTAS
KGMLYLNARNAVINQVAQLNHYADPQMRDVLIFLYNNALMLSAQGAQRIVKPEHAKQIFDANNRVASALMNAITGTTNAV
DVPQATVAPYAVLINTLGNNQVNQELRYVLESAPFFLRIVGIDAAISLTEHSLQSLQQAACIVIDASEPAQTSLLALGAV
WAIAPHVPIIALRSAETEPLAIPIIDVVYDLGVRGEALQRALQELNLAQAASRLTAADFLRYEFVSERLAQALAEQFNSI
DQLLRADPAEVSNLLGVRLAPLGLIEELQRALEEDRGH

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=336, Percent_Identity=25, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI4507677, Length=404, Percent_Identity=22.5247524752475, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI154146191, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI153792590, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI20149594, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI1786679, Length=379, Percent_Identity=27.7044854881267, Blast_Score=146, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI115535167, Length=391, Percent_Identity=23.7851662404092, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115535205, Length=391, Percent_Identity=23.7851662404092, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17559162, Length=429, Percent_Identity=23.3100233100233, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17542208, Length=394, Percent_Identity=23.3502538071066, Blast_Score=92, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325016, Length=198, Percent_Identity=26.7676767676768, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323840, Length=198, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24586016, Length=409, Percent_Identity=22.0048899755501, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357739, Length=464, Percent_Identity=21.551724137931, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17647529, Length=191, Percent_Identity=25.130890052356, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 93990; Mature: 93990

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPHGIRQGQMTINVPGVIRTLGESLYADPHVAIRELLQNAHDTCLVRQADDPNAPLPE
CCCCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
IHVRYDPFGRSLTIEDNGAGMTEAEVEQFLSVIGASNTDAVRSRLEAIGERSLAERLIGR
EEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FGLGMLAAFIIGERIEFVTRSFRSEGEAAVWWECSGEQSYRMGQTTRPTAGTTVTVAIKP
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECC
SQVHLLREDELSRLIRLFADLLSVPIYLDPSPRPVNVMQAPWHSEASESEYIRYLNELYP
CCEEEECHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHCC
SESVLAVIPLNIEEDDGAFKLGGVLFIPKQLYLNVREHGDLIIYVRRMFVCRGERSLLPE
CCCEEEEEEEEEECCCCCEEECCEEEECHHHHEEHHHCCCEEEEEHHHHHHCCCHHCCHH
WAKFVKGVVESPNLRETTSREALRRDEYFERVQRTLGQVILNYLEQLALNDQRLFREVVT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QHNRVIKSWALISDELFIRIKDIVLFDTDAGRMNLPRYFEQSQLSRSGINNDDPHQHLLF
HHHHHHHHHHHHCHHHEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEE
YFTTPGGIGQHAVLFAAKGLRVIDGQYFPDEPFLRRYAELTPNIGLRRLDVGGDFIFEAM
EEECCCCCCCHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCEEEECC
PNKDQRWLELEERYAEMGVEAQVAQYLPESIPAVLIFSENSETNEQVDTLLADPNLSPSI
CCCCHHHHHHHHHHHHCCCHHHHHHHCHHHCCEEEEECCCCCCHHHHHHHHCCCCCCHHH
KQLLRAMLDERKAERKHTASKGMLYLNARNAVINQVAQLNHYADPQMRDVLIFLYNNALM
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCHHHHEEEEEECCEEE
LSAQGAQRIVKPEHAKQIFDANNRVASALMNAITGTTNAVDVPQATVAPYAVLINTLGNN
EECCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
QVNQELRYVLESAPFFLRIVGIDAAISLTEHSLQSLQQAACIVIDASEPAQTSLLALGAV
HHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHH
WAIAPHVPIIALRSAETEPLAIPIIDVVYDLGVRGEALQRALQELNLAQAASRLTAADFL
HHHCCCCCEEEEECCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RYEFVSERLAQALAEQFNSIDQLLRADPAEVSNLLGVRLAPLGLIEELQRALEEDRGH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRPHGIRQGQMTINVPGVIRTLGESLYADPHVAIRELLQNAHDTCLVRQADDPNAPLPE
CCCCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
IHVRYDPFGRSLTIEDNGAGMTEAEVEQFLSVIGASNTDAVRSRLEAIGERSLAERLIGR
EEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FGLGMLAAFIIGERIEFVTRSFRSEGEAAVWWECSGEQSYRMGQTTRPTAGTTVTVAIKP
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECC
SQVHLLREDELSRLIRLFADLLSVPIYLDPSPRPVNVMQAPWHSEASESEYIRYLNELYP
CCEEEECHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHCC
SESVLAVIPLNIEEDDGAFKLGGVLFIPKQLYLNVREHGDLIIYVRRMFVCRGERSLLPE
CCCEEEEEEEEEECCCCCEEECCEEEECHHHHEEHHHCCCEEEEEHHHHHHCCCHHCCHH
WAKFVKGVVESPNLRETTSREALRRDEYFERVQRTLGQVILNYLEQLALNDQRLFREVVT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QHNRVIKSWALISDELFIRIKDIVLFDTDAGRMNLPRYFEQSQLSRSGINNDDPHQHLLF
HHHHHHHHHHHHCHHHEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEE
YFTTPGGIGQHAVLFAAKGLRVIDGQYFPDEPFLRRYAELTPNIGLRRLDVGGDFIFEAM
EEECCCCCCCHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCEEEECC
PNKDQRWLELEERYAEMGVEAQVAQYLPESIPAVLIFSENSETNEQVDTLLADPNLSPSI
CCCCHHHHHHHHHHHHCCCHHHHHHHCHHHCCEEEEECCCCCCHHHHHHHHCCCCCCHHH
KQLLRAMLDERKAERKHTASKGMLYLNARNAVINQVAQLNHYADPQMRDVLIFLYNNALM
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCHHHHEEEEEECCEEE
LSAQGAQRIVKPEHAKQIFDANNRVASALMNAITGTTNAVDVPQATVAPYAVLINTLGNN
EECCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
QVNQELRYVLESAPFFLRIVGIDAAISLTEHSLQSLQQAACIVIDASEPAQTSLLALGAV
HHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHH
WAIAPHVPIIALRSAETEPLAIPIIDVVYDLGVRGEALQRALQELNLAQAASRLTAADFL
HHHCCCCCEEEEECCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RYEFVSERLAQALAEQFNSIDQLLRADPAEVSNLLGVRLAPLGLIEELQRALEEDRGH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA