| Definition | Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome. |
|---|---|
| Accession | NC_009972 |
| Length | 6,346,587 |
Click here to switch to the map view.
The map label for this gene is ppiB [H]
Identifier: 159900714
GI number: 159900714
Start: 5356688
End: 5357203
Strand: Reverse
Name: ppiB [H]
Synonym: Haur_4201
Alternate gene names: 159900714
Gene position: 5357203-5356688 (Counterclockwise)
Preceding gene: 159900715
Following gene: 159900713
Centisome position: 84.41
GC content: 48.64
Gene sequence:
>516_bases ATGTTTTCACGATTCTTTAGTCGAAAGGGGTCTCACGTGGCCGCAAAACAATGGAAGTCAGCGCCAGCGATGTCGATTGA CACCACCAAGCACTATGTCGTCACCATGGAAACAACCAAAGGCACCATCAAAATTGAGTTGTATCCTGAGTATGCACCCA AAACGGTCAATAACTTTGTGTTTTTGATCAACGAAGGGTTTTATGATGGCATCGTCTTCCACCGCGTGATCTCAAACTTT ATGATTCAAGGTGGCGATCCAACTGGTACGGGCACAGGTGGCCCAGGCTATCGCTTCGAAGATGAATTCAAGGGCAATCC ACTTAAGCACGAAACCTGTGTGCTTTCGATGGCTAATGCTGGAGCCAACACCAATGGCTCACAATTCTTCATCACCCATA GCCCACAACCTCACCTCGATGGCCGCCATACCGTGTTTGGCAAAGTCACCGAGGGCCAAGATGTGGTCAATGCAATTCGC CAAGGCGATAGCATGACCAAAGTAACCGTCAGCTAA
Upstream 100 bases:
>100_bases CGCCAAGGCAAGCCTGAGTAGCACGCGTCGTAGCAGATGTTGCTTTGAGCGACCGCCAATTGCTTGCGGTCGCTTTCTTG TGTTATAACCCTAGGGTGAT
Downstream 100 bases:
>100_bases TTTGCGCTGTGGCTCACGAGCAAGCAGCTGATTAACCACGAAGGACACGAAGAACCACGAAGCTCGATTTCGTGAAACTT CGTGTCCTTCGCGGTTAACA
Product: peptidylprolyl isomerase
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 171; Mature: 171
Protein sequence:
>171_residues MFSRFFSRKGSHVAAKQWKSAPAMSIDTTKHYVVTMETTKGTIKIELYPEYAPKTVNNFVFLINEGFYDGIVFHRVISNF MIQGGDPTGTGTGGPGYRFEDEFKGNPLKHETCVLSMANAGANTNGSQFFITHSPQPHLDGRHTVFGKVTEGQDVVNAIR QGDSMTKVTVS
Sequences:
>Translated_171_residues MFSRFFSRKGSHVAAKQWKSAPAMSIDTTKHYVVTMETTKGTIKIELYPEYAPKTVNNFVFLINEGFYDGIVFHRVISNF MIQGGDPTGTGTGGPGYRFEDEFKGNPLKHETCVLSMANAGANTNGSQFFITHSPQPHLDGRHTVFGKVTEGQDVVNAIR QGDSMTKVTVS >Mature_171_residues MFSRFFSRKGSHVAAKQWKSAPAMSIDTTKHYVVTMETTKGTIKIELYPEYAPKTVNNFVFLINEGFYDGIVFHRVISNF MIQGGDPTGTGTGGPGYRFEDEFKGNPLKHETCVLSMANAGANTNGSQFFITHSPQPHLDGRHTVFGKVTEGQDVVNAIR QGDSMTKVTVS
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=140, Percent_Identity=49.2857142857143, Blast_Score=135, Evalue=1e-32, Organism=Homo sapiens, GI24308049, Length=127, Percent_Identity=54.3307086614173, Blast_Score=132, Evalue=2e-31, Organism=Homo sapiens, GI19557636, Length=132, Percent_Identity=52.2727272727273, Blast_Score=130, Evalue=4e-31, Organism=Homo sapiens, GI64276486, Length=130, Percent_Identity=47.6923076923077, Blast_Score=121, Evalue=2e-28, Organism=Homo sapiens, GI10863927, Length=144, Percent_Identity=47.9166666666667, Blast_Score=104, Evalue=3e-23, Organism=Homo sapiens, GI22547212, Length=137, Percent_Identity=48.9051094890511, Blast_Score=104, Evalue=4e-23, Organism=Homo sapiens, GI7657473, Length=137, Percent_Identity=48.9051094890511, Blast_Score=104, Evalue=4e-23, Organism=Homo sapiens, GI22547215, Length=137, Percent_Identity=48.9051094890511, Blast_Score=103, Evalue=5e-23, Organism=Homo sapiens, GI4758950, Length=155, Percent_Identity=47.741935483871, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI4826932, Length=150, Percent_Identity=44.6666666666667, Blast_Score=101, Evalue=4e-22, Organism=Homo sapiens, GI4505991, Length=129, Percent_Identity=54.2635658914729, Blast_Score=100, Evalue=6e-22, Organism=Homo sapiens, GI6631100, Length=135, Percent_Identity=47.4074074074074, Blast_Score=99, Evalue=1e-21, Organism=Homo sapiens, GI42560244, Length=145, Percent_Identity=44.1379310344828, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI5031987, Length=144, Percent_Identity=47.9166666666667, Blast_Score=98, Evalue=3e-21, Organism=Homo sapiens, GI256017253, Length=158, Percent_Identity=43.0379746835443, Blast_Score=98, Evalue=4e-21, Organism=Homo sapiens, GI221139811, Length=158, Percent_Identity=43.0379746835443, Blast_Score=98, Evalue=4e-21, Organism=Homo sapiens, GI256017251, Length=158, Percent_Identity=43.0379746835443, Blast_Score=98, Evalue=4e-21, Organism=Homo sapiens, GI45439316, Length=155, Percent_Identity=43.2258064516129, Blast_Score=96, Evalue=1e-20, Organism=Homo sapiens, GI303305009, Length=153, Percent_Identity=43.7908496732026, Blast_Score=96, Evalue=1e-20, Organism=Homo sapiens, GI5174637, Length=170, Percent_Identity=41.1764705882353, Blast_Score=96, Evalue=1e-20, Organism=Homo sapiens, GI310127646, Length=144, Percent_Identity=45.1388888888889, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI310114371, Length=144, Percent_Identity=45.1388888888889, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI310119221, Length=144, Percent_Identity=45.1388888888889, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI178057341, Length=145, Percent_Identity=43.448275862069, Blast_Score=95, Evalue=3e-20, Organism=Homo sapiens, GI20911035, Length=140, Percent_Identity=40.7142857142857, Blast_Score=94, Evalue=5e-20, Organism=Homo sapiens, GI310129267, Length=144, Percent_Identity=44.4444444444444, Blast_Score=93, Evalue=1e-19, Organism=Homo sapiens, GI310120620, Length=144, Percent_Identity=44.4444444444444, Blast_Score=93, Evalue=1e-19, Organism=Homo sapiens, GI209417936, Length=145, Percent_Identity=43.448275862069, Blast_Score=93, Evalue=1e-19, Organism=Homo sapiens, GI30102944, Length=145, Percent_Identity=43.448275862069, Blast_Score=93, Evalue=1e-19, Organism=Homo sapiens, GI219842199, Length=145, Percent_Identity=43.448275862069, Blast_Score=93, Evalue=1e-19, Organism=Homo sapiens, GI5454154, Length=135, Percent_Identity=47.4074074074074, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI310110104, Length=144, Percent_Identity=43.75, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI150418007, Length=144, Percent_Identity=42.3611111111111, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI169163387, Length=144, Percent_Identity=41.6666666666667, Blast_Score=87, Evalue=8e-18, Organism=Homo sapiens, GI169164185, Length=144, Percent_Identity=42.3611111111111, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI169163623, Length=144, Percent_Identity=42.3611111111111, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI310132444, Length=144, Percent_Identity=41.6666666666667, Blast_Score=83, Evalue=1e-16, Organism=Homo sapiens, GI310113152, Length=144, Percent_Identity=41.6666666666667, Blast_Score=83, Evalue=1e-16, Organism=Homo sapiens, GI169214050, Length=144, Percent_Identity=42.3611111111111, Blast_Score=81, Evalue=4e-16, Organism=Homo sapiens, GI239751853, Length=144, Percent_Identity=42.3611111111111, Blast_Score=80, Evalue=6e-16, Organism=Homo sapiens, GI113428306, Length=144, Percent_Identity=42.3611111111111, Blast_Score=80, Evalue=6e-16, Organism=Homo sapiens, GI27735045, Length=157, Percent_Identity=36.3057324840764, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI310127745, Length=144, Percent_Identity=41.6666666666667, Blast_Score=78, Evalue=4e-15, Organism=Homo sapiens, GI310119290, Length=144, Percent_Identity=41.6666666666667, Blast_Score=78, Evalue=4e-15, Organism=Homo sapiens, GI310114540, Length=144, Percent_Identity=41.6666666666667, Blast_Score=77, Evalue=5e-15, Organism=Homo sapiens, GI14277126, Length=142, Percent_Identity=39.4366197183099, Blast_Score=77, Evalue=9e-15, Organism=Escherichia coli, GI1789763, Length=149, Percent_Identity=38.255033557047, Blast_Score=77, Evalue=7e-16, Organism=Escherichia coli, GI1786736, Length=139, Percent_Identity=35.9712230215827, Blast_Score=68, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17539496, Length=127, Percent_Identity=55.1181102362205, Blast_Score=139, Evalue=6e-34, Organism=Caenorhabditis elegans, GI71980590, Length=132, Percent_Identity=51.5151515151515, Blast_Score=125, Evalue=7e-30, Organism=Caenorhabditis elegans, GI71980594, Length=132, Percent_Identity=51.5151515151515, Blast_Score=125, Evalue=8e-30, Organism=Caenorhabditis elegans, GI17506311, Length=131, Percent_Identity=52.6717557251908, Blast_Score=120, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17532641, Length=135, Percent_Identity=45.9259259259259, Blast_Score=120, Evalue=3e-28, Organism=Caenorhabditis elegans, GI71997782, Length=122, Percent_Identity=50, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17506307, Length=135, Percent_Identity=55.5555555555556, Blast_Score=112, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17552780, Length=128, Percent_Identity=57.8125, Blast_Score=111, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17551284, Length=133, Percent_Identity=51.1278195488722, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17551282, Length=133, Percent_Identity=51.1278195488722, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17539498, Length=129, Percent_Identity=49.6124031007752, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17552782, Length=136, Percent_Identity=50.7352941176471, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17559074, Length=142, Percent_Identity=49.2957746478873, Blast_Score=100, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17552784, Length=140, Percent_Identity=47.1428571428571, Blast_Score=98, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17566266, Length=136, Percent_Identity=48.5294117647059, Blast_Score=95, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17565860, Length=155, Percent_Identity=44.5161290322581, Blast_Score=95, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17532643, Length=146, Percent_Identity=44.5205479452055, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI32563659, Length=140, Percent_Identity=35.7142857142857, Blast_Score=81, Evalue=2e-16, Organism=Caenorhabditis elegans, GI115533296, Length=133, Percent_Identity=37.593984962406, Blast_Score=63, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323562, Length=166, Percent_Identity=46.3855421686747, Blast_Score=110, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6320359, Length=138, Percent_Identity=50, Blast_Score=105, Evalue=5e-24, Organism=Saccharomyces cerevisiae, GI6323246, Length=138, Percent_Identity=47.8260869565217, Blast_Score=104, Evalue=9e-24, Organism=Saccharomyces cerevisiae, GI6321848, Length=135, Percent_Identity=51.1111111111111, Blast_Score=98, Evalue=6e-22, Organism=Saccharomyces cerevisiae, GI6320510, Length=130, Percent_Identity=50.7692307692308, Blast_Score=96, Evalue=4e-21, Organism=Saccharomyces cerevisiae, GI6322492, Length=158, Percent_Identity=37.3417721518987, Blast_Score=77, Evalue=2e-15, Organism=Drosophila melanogaster, GI17986117, Length=132, Percent_Identity=53.7878787878788, Blast_Score=139, Evalue=9e-34, Organism=Drosophila melanogaster, GI19922376, Length=129, Percent_Identity=48.062015503876, Blast_Score=130, Evalue=3e-31, Organism=Drosophila melanogaster, GI24652460, Length=131, Percent_Identity=43.5114503816794, Blast_Score=114, Evalue=3e-26, Organism=Drosophila melanogaster, GI21357249, Length=135, Percent_Identity=42.962962962963, Blast_Score=113, Evalue=5e-26, Organism=Drosophila melanogaster, GI19922912, Length=141, Percent_Identity=51.7730496453901, Blast_Score=107, Evalue=5e-24, Organism=Drosophila melanogaster, GI20130249, Length=129, Percent_Identity=55.8139534883721, Blast_Score=106, Evalue=6e-24, Organism=Drosophila melanogaster, GI45549139, Length=144, Percent_Identity=49.3055555555556, Blast_Score=106, Evalue=6e-24, Organism=Drosophila melanogaster, GI24650807, Length=135, Percent_Identity=48.1481481481481, Blast_Score=106, Evalue=7e-24, Organism=Drosophila melanogaster, GI24664125, Length=128, Percent_Identity=52.34375, Blast_Score=101, Evalue=3e-22, Organism=Drosophila melanogaster, GI21357783, Length=128, Percent_Identity=52.34375, Blast_Score=101, Evalue=3e-22, Organism=Drosophila melanogaster, GI17647301, Length=134, Percent_Identity=46.2686567164179, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI17136360, Length=130, Percent_Identity=44.6153846153846, Blast_Score=90, Evalue=7e-19, Organism=Drosophila melanogaster, GI24586038, Length=153, Percent_Identity=39.2156862745098, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI21355677, Length=137, Percent_Identity=36.4963503649635, Blast_Score=78, Evalue=3e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 18858; Mature: 18858
Theoretical pI: Translated: 9.00; Mature: 9.00
Prosite motif: PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFSRFFSRKGSHVAAKQWKSAPAMSIDTTKHYVVTMETTKGTIKIELYPEYAPKTVNNFV CCCHHHHCCCCEEHHHHHCCCCCEEEECCCEEEEEEECCCCEEEEEEECCCCCCCCCCEE FLINEGFYDGIVFHRVISNFMIQGGDPTGTGTGGPGYRFEDEFKGNPLKHETCVLSMANA EEEECCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC GANTNGSQFFITHSPQPHLDGRHTVFGKVTEGQDVVNAIRQGDSMTKVTVS CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCEEEEEEC >Mature Secondary Structure MFSRFFSRKGSHVAAKQWKSAPAMSIDTTKHYVVTMETTKGTIKIELYPEYAPKTVNNFV CCCHHHHCCCCEEHHHHHCCCCCEEEECCCEEEEEEECCCCEEEEEEECCCCCCCCCCEE FLINEGFYDGIVFHRVISNFMIQGGDPTGTGTGGPGYRFEDEFKGNPLKHETCVLSMANA EEEECCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC GANTNGSQFFITHSPQPHLDGRHTVFGKVTEGQDVVNAIRQGDSMTKVTVS CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9317025; 9665876 [H]