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The map label for this gene is yciC [H]

Identifier: 159900713

GI number: 159900713

Start: 5355563

End: 5356573

Strand: Reverse

Name: yciC [H]

Synonym: Haur_4200

Alternate gene names: 159900713

Gene position: 5356573-5355563 (Counterclockwise)

Preceding gene: 159900714

Following gene: 159900712

Centisome position: 84.4

GC content: 49.95

Gene sequence:

>1011_bases
ATGACCACGCCGATTCCAATGACGATTTTGACCGGATTTTTGGGCGCAGGCAAAACGACGTTGCTCAATCGGCTGCTTAG
TGCCCAGCATGGCCTCAAAATCGCGGTGCTGGTTAACGATTTTGGCGAGATTAATATTGACTCGCAGTTGGTAGTTGGGG
TTGAAAATGACGCTGTAATTAATTTGGCGAATGGCTGTATTTGCTGCACCATTCGCGAGGATTTACTCACCACCACCCTC
GAATTGCTTGAGCGCGATGATCGACCTGAATATATCATCGTCGAAGCCAGCGGCGTTTCCGACCCGGTTTCGGTGGCATT
AACCTTCCGTTTGCCCGCCCTGCGCTCGTTGATCAATCTCGATTCGATTGTGGCGGTCGTTGATGCTGAGAGTATTCACC
AACAACGTGAACAATTGATTCAAGTCGTCGATCAAATTGCCGCCGCCGATCTTGTTGTGATCAATAAAATCGATTTGGTT
GATGCTGCCCAACAGCAACGGGTGATTGCCTGGATTCAGACGATTGTGCCACGGGCGCGAATTTTGACCGCTGAATATGG
CGAGGTTCCGGTTGATTTGCTGCTGGGAGTTGGTCAATATCGCATCGATTTGCAGGCTGAAGCGTATCCCACCCAGCATC
AACATAACGAAGAATGGCAAACCTGGAATTACCAAACTGATCAGCCTTTTACCATGAGCAGCCTGCAACGAGCCTTCCAA
CAATTGCCAACCGCGATTTTTCGTGCTAAAGGCATTGTATATTTGGCCGAAGCACCTGAACGCCGCGCAATTGTTCAGTT
GGCGGGCAAACGTACTAGTTTGCGGCTCAGTGAGCCATGGGGCGCAGCCACTCCGTACAGCCAAATTGTGATAATTGGCC
GGAGCAATAGCTTTGATCCAGCTGAATTGACCCACCATTTTAATGCTTGTTTGGCAGATGCCACGCAAGAACCACGCGAA
GAAATTCTGACTGTGGCCGAATGGCGACGCAAATACCAAGCCCAATCGTAA

Upstream 100 bases:

>100_bases
CACGAGCAAGCAGCTGATTAACCACGAAGGACACGAAGAACCACGAAGCTCGATTTCGTGAAACTTCGTGTCCTTCGCGG
TTAACAATAAGGAGTGTCTG

Downstream 100 bases:

>100_bases
AACTAATAGATTTAGTCTTGACAAATCATTTAAAGACTATTATGATTAGTCTTGAAAACTAATGAAATTAGTCTTTAGGT
GAATCATGTCAAATACTAGT

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTTPIPMTILTGFLGAGKTTLLNRLLSAQHGLKIAVLVNDFGEINIDSQLVVGVENDAVINLANGCICCTIREDLLTTTL
ELLERDDRPEYIIVEASGVSDPVSVALTFRLPALRSLINLDSIVAVVDAESIHQQREQLIQVVDQIAAADLVVINKIDLV
DAAQQQRVIAWIQTIVPRARILTAEYGEVPVDLLLGVGQYRIDLQAEAYPTQHQHNEEWQTWNYQTDQPFTMSSLQRAFQ
QLPTAIFRAKGIVYLAEAPERRAIVQLAGKRTSLRLSEPWGAATPYSQIVIIGRSNSFDPAELTHHFNACLADATQEPRE
EILTVAEWRRKYQAQS

Sequences:

>Translated_336_residues
MTTPIPMTILTGFLGAGKTTLLNRLLSAQHGLKIAVLVNDFGEINIDSQLVVGVENDAVINLANGCICCTIREDLLTTTL
ELLERDDRPEYIIVEASGVSDPVSVALTFRLPALRSLINLDSIVAVVDAESIHQQREQLIQVVDQIAAADLVVINKIDLV
DAAQQQRVIAWIQTIVPRARILTAEYGEVPVDLLLGVGQYRIDLQAEAYPTQHQHNEEWQTWNYQTDQPFTMSSLQRAFQ
QLPTAIFRAKGIVYLAEAPERRAIVQLAGKRTSLRLSEPWGAATPYSQIVIIGRSNSFDPAELTHHFNACLADATQEPRE
EILTVAEWRRKYQAQS
>Mature_335_residues
TTPIPMTILTGFLGAGKTTLLNRLLSAQHGLKIAVLVNDFGEINIDSQLVVGVENDAVINLANGCICCTIREDLLTTTLE
LLERDDRPEYIIVEASGVSDPVSVALTFRLPALRSLINLDSIVAVVDAESIHQQREQLIQVVDQIAAADLVVINKIDLVD
AAQQQRVIAWIQTIVPRARILTAEYGEVPVDLLLGVGQYRIDLQAEAYPTQHQHNEEWQTWNYQTDQPFTMSSLQRAFQQ
LPTAIFRAKGIVYLAEAPERRAIVQLAGKRTSLRLSEPWGAATPYSQIVIIGRSNSFDPAELTHHFNACLADATQEPREE
ILTVAEWRRKYQAQS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=206, Percent_Identity=35.4368932038835, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI126722884, Length=206, Percent_Identity=34.9514563106796, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI223941779, Length=193, Percent_Identity=36.2694300518135, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI148727351, Length=206, Percent_Identity=33.9805825242718, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI146231952, Length=211, Percent_Identity=32.7014218009479, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI223941776, Length=197, Percent_Identity=32.994923857868, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI119120938, Length=135, Percent_Identity=37.7777777777778, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI87082430, Length=306, Percent_Identity=31.0457516339869, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788499, Length=211, Percent_Identity=29.8578199052133, Blast_Score=88, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=224, Percent_Identity=28.125, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 37387; Mature: 37256

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPIPMTILTGFLGAGKTTLLNRLLSAQHGLKIAVLVNDFGEINIDSQLVVGVENDAVI
CCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEECCCCEE
NLANGCICCTIREDLLTTTLELLERDDRPEYIIVEASGVSDPVSVALTFRLPALRSLINL
EECCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECHHHHHHHHH
DSIVAVVDAESIHQQREQLIQVVDQIAAADLVVINKIDLVDAAQQQRVIAWIQTIVPRAR
HHHHEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHH
ILTAEYGEVPVDLLLGVGQYRIDLQAEAYPTQHQHNEEWQTWNYQTDQPFTMSSLQRAFQ
EEECCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QLPTAIFRAKGIVYLAEAPERRAIVQLAGKRTSLRLSEPWGAATPYSQIVIIGRSNSFDP
HHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCH
AELTHHFNACLADATQEPREEILTVAEWRRKYQAQS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTPIPMTILTGFLGAGKTTLLNRLLSAQHGLKIAVLVNDFGEINIDSQLVVGVENDAVI
CCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEECCCCEE
NLANGCICCTIREDLLTTTLELLERDDRPEYIIVEASGVSDPVSVALTFRLPALRSLINL
EECCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECHHHHHHHHH
DSIVAVVDAESIHQQREQLIQVVDQIAAADLVVINKIDLVDAAQQQRVIAWIQTIVPRAR
HHHHEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHH
ILTAEYGEVPVDLLLGVGQYRIDLQAEAYPTQHQHNEEWQTWNYQTDQPFTMSSLQRAFQ
EEECCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QLPTAIFRAKGIVYLAEAPERRAIVQLAGKRTSLRLSEPWGAATPYSQIVIIGRSNSFDP
HHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCH
AELTHHFNACLADATQEPREEILTVAEWRRKYQAQS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]