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The map label for this gene is rsbRA [H]

Identifier: 159900666

GI number: 159900666

Start: 5300424

End: 5301701

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_4153

Alternate gene names: 159900666

Gene position: 5301701-5300424 (Counterclockwise)

Preceding gene: 159900667

Following gene: 159900663

Centisome position: 83.54

GC content: 50.86

Gene sequence:

>1278_bases
ATGCAAGCTTTTGGTTTGTTCAAAACAATGGGGTTTCGTCAGCGTTTATTTTTGGCGCTCAGCAGCCTGAGTGTCTTAGT
GCTAGCGGTCGCGCTGTTGGCCTTCTTTACCTTGCAATCAATTCGCCGCACCTCACGGGCTGCGGCGAACGACCGTGAAA
TGAGCATTTTGGCCAGCGAAATTTCAATCCATGCCTTGCAATGTCGGCGCTACGAAAAAGATTTTTTGCTCAATGCTGGC
AATATTGCAGCCCAAGATGAACCATTGCAACAGTGGCATGCCGCCAGTTTTGAGCTAGGCAAGTCGATTAAAGCCTTTGA
AGATGCGTCAACCAACGAACTTGATCAAGCACAGGCTCAGGCTTGGCGTGAGGCTTGGCGCGACTATGTGCGCGGCTTCA
GCAGTGTGGAAATTGCGGTTAACGAAGGCTCGATCAACGATACGCAGGCGGCAGTCAAAACCTTTGAGGCTGCTCAAAAC
AACATTCAAATCTTAACCGACCAGTCCTATGATCTGGCCGAAGTCAAAAACCATGCTTCGCAGGCCAGTAGTGCCGAGCT
TGATTTAGCAGGGCAGCAAGCGATTATGCGCCTAACGGTTATTTCTGGCGTGATTGTGCTGCTGGCATTATTGACCTCGT
GGCGCTTCCCACGTTGGTTGATCAAGCCGATTCAGAAATTACAAACCAGCGCTGAACGCCTAGCCAGCGGCGATCTTTCG
GCGCGAACTGGGCTGCGACTGAACGATGAAATTGGCATGCTGGGGCGCAGCTTCGATGAAATGGCCCAAACGCTTGAGCA
AAATACCAACGATTTGGCCAATGAATATATTGTTGCCCAAACCGCCCGTGAAGAAGCCGAAGCCGCCCGTAGCCAAATCG
AGCAACAGCTATTTATGATTCAGCAGCAAGCTCAAGTGATTGCTGAAATGAGCACGCCAATTTTGCCATTAACCAGCCAC
GCTTTGGTCATGCCCTTGGTTGGCGCATTGGATCAACAACGGATTCAACAGGCTCAAGCTCGTGCCTTGGAAGCAATTCA
AGAACGGCGGGCCAAATATTTGTTGCTCGATATTACCGCCGTGCCAGTGATCGATACCCAAGTTGGACAAAGCTTGCTGC
ACCTCCTTCGTGCGGCGCATTTGCTTGGTTGTCGTTTGATGTTAGTTGGTGTGCGCCCCGATGTTGCCCAAACCATCGTT
GGGCTGGGGATTGATCTTGGCGATATTGCCACCTGTAGCAGTTTGCAAAGTGGCATTGATCGGGTGCTTAATCACTAG

Upstream 100 bases:

>100_bases
GGGTTAAATCGAACGAAGGAATTTTTCGCCAAGCAACTGCCGCCCAAGATCTGCCTAAACGGCGCTATTAGTCGGTTGAG
AATTGGCTGAGGTATGGTTC

Downstream 100 bases:

>100_bases
GCTAAGCCAGAACAACGGCGTTCTGGCTTAGCCGATTAGGCATGAGCTTGCAGTTCAGCCAAGACTGCGGCTAAACTGGC
ATATTGGCGGGCCGCTACCG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MQAFGLFKTMGFRQRLFLALSSLSVLVLAVALLAFFTLQSIRRTSRAAANDREMSILASEISIHALQCRRYEKDFLLNAG
NIAAQDEPLQQWHAASFELGKSIKAFEDASTNELDQAQAQAWREAWRDYVRGFSSVEIAVNEGSINDTQAAVKTFEAAQN
NIQILTDQSYDLAEVKNHASQASSAELDLAGQQAIMRLTVISGVIVLLALLTSWRFPRWLIKPIQKLQTSAERLASGDLS
ARTGLRLNDEIGMLGRSFDEMAQTLEQNTNDLANEYIVAQTAREEAEAARSQIEQQLFMIQQQAQVIAEMSTPILPLTSH
ALVMPLVGALDQQRIQQAQARALEAIQERRAKYLLLDITAVPVIDTQVGQSLLHLLRAAHLLGCRLMLVGVRPDVAQTIV
GLGIDLGDIATCSSLQSGIDRVLNH

Sequences:

>Translated_425_residues
MQAFGLFKTMGFRQRLFLALSSLSVLVLAVALLAFFTLQSIRRTSRAAANDREMSILASEISIHALQCRRYEKDFLLNAG
NIAAQDEPLQQWHAASFELGKSIKAFEDASTNELDQAQAQAWREAWRDYVRGFSSVEIAVNEGSINDTQAAVKTFEAAQN
NIQILTDQSYDLAEVKNHASQASSAELDLAGQQAIMRLTVISGVIVLLALLTSWRFPRWLIKPIQKLQTSAERLASGDLS
ARTGLRLNDEIGMLGRSFDEMAQTLEQNTNDLANEYIVAQTAREEAEAARSQIEQQLFMIQQQAQVIAEMSTPILPLTSH
ALVMPLVGALDQQRIQQAQARALEAIQERRAKYLLLDITAVPVIDTQVGQSLLHLLRAAHLLGCRLMLVGVRPDVAQTIV
GLGIDLGDIATCSSLQSGIDRVLNH
>Mature_425_residues
MQAFGLFKTMGFRQRLFLALSSLSVLVLAVALLAFFTLQSIRRTSRAAANDREMSILASEISIHALQCRRYEKDFLLNAG
NIAAQDEPLQQWHAASFELGKSIKAFEDASTNELDQAQAQAWREAWRDYVRGFSSVEIAVNEGSINDTQAAVKTFEAAQN
NIQILTDQSYDLAEVKNHASQASSAELDLAGQQAIMRLTVISGVIVLLALLTSWRFPRWLIKPIQKLQTSAERLASGDLS
ARTGLRLNDEIGMLGRSFDEMAQTLEQNTNDLANEYIVAQTAREEAEAARSQIEQQLFMIQQQAQVIAEMSTPILPLTSH
ALVMPLVGALDQQRIQQAQARALEAIQERRAKYLLLDITAVPVIDTQVGQSLLHLLRAAHLLGCRLMLVGVRPDVAQTIV
GLGIDLGDIATCSSLQSGIDRVLNH

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 46876; Mature: 46876

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50885 HAMP ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFGLFKTMGFRQRLFLALSSLSVLVLAVALLAFFTLQSIRRTSRAAANDREMSILASE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ISIHALQCRRYEKDFLLNAGNIAAQDEPLQQWHAASFELGKSIKAFEDASTNELDQAQAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHH
AWREAWRDYVRGFSSVEIAVNEGSINDTQAAVKTFEAAQNNIQILTDQSYDLAEVKNHAS
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
QASSAELDLAGQQAIMRLTVISGVIVLLALLTSWRFPRWLIKPIQKLQTSAERLASGDLS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ARTGLRLNDEIGMLGRSFDEMAQTLEQNTNDLANEYIVAQTAREEAEAARSQIEQQLFMI
CCCCCCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQQAQVIAEMSTPILPLTSHALVMPLVGALDQQRIQQAQARALEAIQERRAKYLLLDITA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEC
VPVIDTQVGQSLLHLLRAAHLLGCRLMLVGVRPDVAQTIVGLGIDLGDIATCSSLQSGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
RVLNH
HHHCC
>Mature Secondary Structure
MQAFGLFKTMGFRQRLFLALSSLSVLVLAVALLAFFTLQSIRRTSRAAANDREMSILASE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ISIHALQCRRYEKDFLLNAGNIAAQDEPLQQWHAASFELGKSIKAFEDASTNELDQAQAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHH
AWREAWRDYVRGFSSVEIAVNEGSINDTQAAVKTFEAAQNNIQILTDQSYDLAEVKNHAS
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHH
QASSAELDLAGQQAIMRLTVISGVIVLLALLTSWRFPRWLIKPIQKLQTSAERLASGDLS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ARTGLRLNDEIGMLGRSFDEMAQTLEQNTNDLANEYIVAQTAREEAEAARSQIEQQLFMI
CCCCCCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQQAQVIAEMSTPILPLTSHALVMPLVGALDQQRIQQAQARALEAIQERRAKYLLLDITA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEC
VPVIDTQVGQSLLHLLRAAHLLGCRLMLVGVRPDVAQTIVGLGIDLGDIATCSSLQSGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
RVLNH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]