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The map label for this gene is citZ [H]

Identifier: 159900658

GI number: 159900658

Start: 5292933

End: 5294120

Strand: Reverse

Name: citZ [H]

Synonym: Haur_4145

Alternate gene names: 159900658

Gene position: 5294120-5292933 (Counterclockwise)

Preceding gene: 159900660

Following gene: 159900657

Centisome position: 83.42

GC content: 53.96

Gene sequence:

>1188_bases
ATGACGCGCTATTTGAGTGCTCGCGAAGTGGCCGAGCATTTGGGAATTAGTGTGCCAACCGTTTATGCCTATGTAAGCCG
CGGGTTGTTGCACTCGGAGCCAGCCGGAGCGCATGCGCATCGCTATTTATTTGATGAGGTTGAGCAATTGAAATTACGCC
GCGAAGGTCGGCGCAATCCGGCCAGTGTGGCGGCTGGCGCATTGCACTGGGGCACGCCAGTGCTCGATTCAGCGATCACG
CTGATCGACAATCAACAGGTCTATTATCGTGGGTTCGATGTGCGCGAATTGGCCAGTAGTGCCAGCATCGAAGAGGTTGC
GAGCCTGATTTGGGTCGGCGATCGGCAACAAAGCCAGCAATTATGGGGAGATTTGCCAGCGCTAAACATTCCCCAGTTGC
CTGATCTACCGTTGCTTGAGCAATTTGTCGTGGCGTTGGCGATGGTTGGCAGCAACGATCATGCCGCTTTCGATCAACGC
CCGCAAGGCTTGCAACGCACAGCGGTACGCGTGGTGCAGTTGTTGATCAGCGTAGCCGCCAAACGTCCCTTGCAAGGCCC
AATCGTGGCGCAATTGGCCGAGGCATGGCAGATTCCGCCAAATTTACAGCCGTTGCTCAACGCTGCATTAATTGTCAGCG
CCGATCATGAACTCAATGTTTCATCGTTTACTGCTCGCTGCGTAGCTTCGGCAGGCACAACCTTATATGCTGTAGTTAGT
GCGGGTTTAGCGGCGTTGGGTGGAGTGCATCATGGCAAGCAAAGCGAATTAAGCGAACTGCTGTTGGATGAACTTTTGCG
TAGCCCCGATATCTATGCGGCGTTGGCTCAAAAACTGCGCTTAGGCCAGCCAATTCCAGGTTTTGGCCACCCGATGTATC
CCAATGGCGACCCACGCGGCAAGGTGTTGCTCGATCTGATTCGGCAATTAGCGCCGCAATGTAGCAACGATATTGATCGC
ATTATCCAAGCCGTTTATGAATTGTTGGGCGATCATCCGACGATCGATTTTGGCTTGGCGTGGGTTGGGCGGGTGCTAAA
TTTGCCCTTGGGCAGCGCAATGAGCCTATTTGCCCTAGGCCGCAGCGTTGGCTGGATTGGTCATGCCTTAGAGCAATATA
GCGATGCACGGTTGATTCGGCCACGCGCTCGCTACACCGGCGAACGGCCAAATATAATCAAGATTTAA

Upstream 100 bases:

>100_bases
CAATTTTGCCGCTTGAAATTCCTGCTGCTATCGACTATAAATAGATTTATCAATGTTGTCAATGTTGATTGATAAATCAA
TATTGGAATGGAGCAACGCA

Downstream 100 bases:

>100_bases
CCTGTGCTGCAACGCGTTATTTAGCCGATTCTAATGGGCTAAATTGAGCTTTTAAGCACTACTTGACAAAATATCTAAAT
CGCACTATTATTCGCGACAT

Product: citrate synthase

Products: NA

Alternate protein names: Citrate synthase II [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTRYLSAREVAEHLGISVPTVYAYVSRGLLHSEPAGAHAHRYLFDEVEQLKLRREGRRNPASVAAGALHWGTPVLDSAIT
LIDNQQVYYRGFDVRELASSASIEEVASLIWVGDRQQSQQLWGDLPALNIPQLPDLPLLEQFVVALAMVGSNDHAAFDQR
PQGLQRTAVRVVQLLISVAAKRPLQGPIVAQLAEAWQIPPNLQPLLNAALIVSADHELNVSSFTARCVASAGTTLYAVVS
AGLAALGGVHHGKQSELSELLLDELLRSPDIYAALAQKLRLGQPIPGFGHPMYPNGDPRGKVLLDLIRQLAPQCSNDIDR
IIQAVYELLGDHPTIDFGLAWVGRVLNLPLGSAMSLFALGRSVGWIGHALEQYSDARLIRPRARYTGERPNIIKI

Sequences:

>Translated_395_residues
MTRYLSAREVAEHLGISVPTVYAYVSRGLLHSEPAGAHAHRYLFDEVEQLKLRREGRRNPASVAAGALHWGTPVLDSAIT
LIDNQQVYYRGFDVRELASSASIEEVASLIWVGDRQQSQQLWGDLPALNIPQLPDLPLLEQFVVALAMVGSNDHAAFDQR
PQGLQRTAVRVVQLLISVAAKRPLQGPIVAQLAEAWQIPPNLQPLLNAALIVSADHELNVSSFTARCVASAGTTLYAVVS
AGLAALGGVHHGKQSELSELLLDELLRSPDIYAALAQKLRLGQPIPGFGHPMYPNGDPRGKVLLDLIRQLAPQCSNDIDR
IIQAVYELLGDHPTIDFGLAWVGRVLNLPLGSAMSLFALGRSVGWIGHALEQYSDARLIRPRARYTGERPNIIKI
>Mature_394_residues
TRYLSAREVAEHLGISVPTVYAYVSRGLLHSEPAGAHAHRYLFDEVEQLKLRREGRRNPASVAAGALHWGTPVLDSAITL
IDNQQVYYRGFDVRELASSASIEEVASLIWVGDRQQSQQLWGDLPALNIPQLPDLPLLEQFVVALAMVGSNDHAAFDQRP
QGLQRTAVRVVQLLISVAAKRPLQGPIVAQLAEAWQIPPNLQPLLNAALIVSADHELNVSSFTARCVASAGTTLYAVVSA
GLAALGGVHHGKQSELSELLLDELLRSPDIYAALAQKLRLGQPIPGFGHPMYPNGDPRGKVLLDLIRQLAPQCSNDIDRI
IQAVYELLGDHPTIDFGLAWVGRVLNLPLGSAMSLFALGRSVGWIGHALEQYSDARLIRPRARYTGERPNIIKI

Specific function: Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect [H]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786939, Length=367, Percent_Identity=25.3405994550409, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786527, Length=195, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 43116; Mature: 42985

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYLSAREVAEHLGISVPTVYAYVSRGLLHSEPAGAHAHRYLFDEVEQLKLRREGRRNP
CCCCCCHHHHHHHHCCCHHHHHHHHHHCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
ASVAAGALHWGTPVLDSAITLIDNQQVYYRGFDVRELASSASIEEVASLIWVGDRQQSQQ
HHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCCCHHHHHHHHHCCCCHHHHH
LWGDLPALNIPQLPDLPLLEQFVVALAMVGSNDHAAFDQRPQGLQRTAVRVVQLLISVAA
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KRPLQGPIVAQLAEAWQIPPNLQPLLNAALIVSADHELNVSSFTARCVASAGTTLYAVVS
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCHHHHHHHH
AGLAALGGVHHGKQSELSELLLDELLRSPDIYAALAQKLRLGQPIPGFGHPMYPNGDPRG
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
KVLLDLIRQLAPQCSNDIDRIIQAVYELLGDHPTIDFGLAWVGRVLNLPLGSAMSLFALG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
RSVGWIGHALEQYSDARLIRPRARYTGERPNIIKI
HHHHHHHHHHHHHCCCHHCCCHHHCCCCCCCEECC
>Mature Secondary Structure 
TRYLSAREVAEHLGISVPTVYAYVSRGLLHSEPAGAHAHRYLFDEVEQLKLRREGRRNP
CCCCCHHHHHHHHCCCHHHHHHHHHHCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
ASVAAGALHWGTPVLDSAITLIDNQQVYYRGFDVRELASSASIEEVASLIWVGDRQQSQQ
HHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCCCHHHHHHHHHCCCCHHHHH
LWGDLPALNIPQLPDLPLLEQFVVALAMVGSNDHAAFDQRPQGLQRTAVRVVQLLISVAA
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KRPLQGPIVAQLAEAWQIPPNLQPLLNAALIVSADHELNVSSFTARCVASAGTTLYAVVS
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCHHHHHHHH
AGLAALGGVHHGKQSELSELLLDELLRSPDIYAALAQKLRLGQPIPGFGHPMYPNGDPRG
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
KVLLDLIRQLAPQCSNDIDRIIQAVYELLGDHPTIDFGLAWVGRVLNLPLGSAMSLFALG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
RSVGWIGHALEQYSDARLIRPRARYTGERPNIIKI
HHHHHHHHHHHHHCCCHHCCCHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045898; 9387221; 9384377 [H]