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The map label for this gene is tig

Identifier: 159900400

GI number: 159900400

Start: 4878350

End: 4879795

Strand: Direct

Name: tig

Synonym: Haur_3885

Alternate gene names: 159900400

Gene position: 4878350-4879795 (Clockwise)

Preceding gene: 159900399

Following gene: 159900407

Centisome position: 76.87

GC content: 50.35

Gene sequence:

>1446_bases
GTGAAAGTCACAACTGAACAATTACCAAAGCGCATTGTTGCGCTTGAGATCGAGCCAGACGCAGCGACGATAGAAAAAGA
ATTGAACAAGGCCGCGCAACGGATTGCCAGCAAGGTTGCCATTCCAGGCTTCCGCAAAGGTAAAGCTCCTCGCTTTATCG
TTGAAAACTACTATGGCAAGGCCGCAATTTTAGAAGAAGCGACCGACGAAATTATCAATGTAGCCTTCCGCGCTGCACTC
GAACAAGAAAATATCAAGCCAGTCGCTCAAGCTTCCTTAGAAAAATTAGAGCCAGAGCCATTCCGCTTCCGTATCTTGGT
TCCGGTTGAGCCAGAAGTGATCTTGCCCGATTACAAGGCGATCACGGTTGATCTCACCGAAGAACCAGTTACCGATGCAA
CCTTGGAAGTTGCCTTGGATCAAGCTCGTGAAAAACACGTCGTTTTGAGCGCTCCCGAAGGCGAGCCAGAAGCCGCTGAA
GGCGATCAACTCACCGCAACCGTCCAAACCTTGGTCGATGGTGTGCCTTTGCATAAACTCGACGAAGAGGATGATGACGA
TGATGACGATGACGACGACGATGATGATGACGACGACGATGATGATGATGATGATGACGATGATGACGATGACGATGACG
ATGATGACGACGACGACGATGACGATGATGACGACGATGACGACGATGACGATGATGAAGGCGAACCAACGACCTTAATC
ATGGAAGAACGCCGCATCGTGCCTGAACTGTATGCAGGCTTGAAAGGCATCAAAGCTGGTGAAACTCGCGAAATCAGCGC
TCACCTGCCAGCCGATCATCCAGATGCACGGGTTGCCGATAAAGATGTTGTATTCAAAGTAACTGTCAGCGAAATTCAAA
ATCGCCAATTGCCAGCATGGGAAGAACTCCCAGGTTTGGAAGAATTTGAAGGCGATTTGGATGCCTACAAGGCTGACCTC
ATGGAGCGTTTGGTCAAGAATTCAGGCGATCACCATCGCCGCAATGTCTTGAACCAATACCTCGAAGAAGTTGTCGCTGC
AACCAGCTTCGATGTGCCCGATGCCTTGATTGCTGAACGCGCCCACGAATTGCTCCACGAGCAAGTTGAATCGTTGGCTC
GCTATGGCATCAACATGGAGCAATACCTGCAAATCGTTGGCAAAACCCACGACGAAGCAGTCCAAGAATTGTTGCCCCGT
GGCGAAGAAAGCTTGAAATCATCGTTGGTTGTGCGCAAAATCGTTGAAGCCGAAGGCTTGAGCGTTGACGAAAGCGAAAT
CAATGCTGAAATCGAACGCATCTTGAACGATTTCCCTGATGCCCAACGTGGCCCAGCCCGCCGCCGCCTCGAAAAAGAAT
TGCGGCCTCAAGTTGCTGGCTCGTTGCTCGACAAGAAATTGCAAGATCGCTTGGTCGAATTGGCAACTGGCAACGCCGCT
GCCTAA

Upstream 100 bases:

>100_bases
CTAGCCCCGCCTGAGCGATGTTCTGGTATAATGTCACGCTAGACTGCCTTCGTTGGCGATAGTTAAAGATCGCTTAAATA
CCATATACTTTGGAGATCGT

Downstream 100 bases:

>100_bases
TTCCAAACCGCATCAAGCCCCCTTGTCCTAGCAATTGGGCAAGGGGGTTTTTTGTTTAAAGGCAAAAGGCAAAAATCAAA
AGTTAGAAGCGGGTCAGGGG

Product: trigger factor domain-containing protein

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGKAAILEEATDEIINVAFRAAL
EQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKAITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAE
GDQLTATVQTLVDGVPLHKLDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLI
MEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAWEELPGLEEFEGDLDAYKADL
MERLVKNSGDHHRRNVLNQYLEEVVAATSFDVPDALIAERAHELLHEQVESLARYGINMEQYLQIVGKTHDEAVQELLPR
GEESLKSSLVVRKIVEAEGLSVDESEINAEIERILNDFPDAQRGPARRRLEKELRPQVAGSLLDKKLQDRLVELATGNAA
A

Sequences:

>Translated_481_residues
MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGKAAILEEATDEIINVAFRAAL
EQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKAITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAE
GDQLTATVQTLVDGVPLHKLDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLI
MEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAWEELPGLEEFEGDLDAYKADL
MERLVKNSGDHHRRNVLNQYLEEVVAATSFDVPDALIAERAHELLHEQVESLARYGINMEQYLQIVGKTHDEAVQELLPR
GEESLKSSLVVRKIVEAEGLSVDESEINAEIERILNDFPDAQRGPARRRLEKELRPQVAGSLLDKKLQDRLVELATGNAA
A
>Mature_481_residues
MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGKAAILEEATDEIINVAFRAAL
EQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKAITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAE
GDQLTATVQTLVDGVPLHKLDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLI
MEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAWEELPGLEEFEGDLDAYKADL
MERLVKNSGDHHRRNVLNQYLEEVVAATSFDVPDALIAERAHELLHEQVESLARYGINMEQYLQIVGKTHDEAVQELLPR
GEESLKSSLVVRKIVEAEGLSVDESEINAEIERILNDFPDAQRGPARRRLEKELRPQVAGSLLDKKLQDRLVELATGNAA
A

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

None

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_HERA2 (A9AUT1)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546647.1
- ProteinModelPortal:   A9AUT1
- GeneID:   5735746
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3885
- HOGENOM:   HBG403392
- OMA:   TIDFKTI
- ProtClustDB:   CLSK974889
- BioCyc:   HAUR316274:HAUR_3885-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 53732; Mature: 53732

Theoretical pI: Translated: 3.91; Mature: 3.91

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGK
CCCCHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHCCCC
AAILEEATDEIINVAFRAALEQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCEECCCCEE
ITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAEGDQLTATVQTLVDGVPLHKL
EEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
MEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAW
HHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCH
EELPGLEEFEGDLDAYKADLMERLVKNSGDHHRRNVLNQYLEEVVAATSFDVPDALIAER
HHCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHELLHEQVESLARYGINMEQYLQIVGKTHDEAVQELLPRGEESLKSSLVVRKIVEAEGL
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
SVDESEINAEIERILNDFPDAQRGPARRRLEKELRPQVAGSLLDKKLQDRLVELATGNAA
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
A
C
>Mature Secondary Structure
MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGK
CCCCHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHCCCC
AAILEEATDEIINVAFRAALEQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCCCEECCCCEE
ITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAEGDQLTATVQTLVDGVPLHKL
EEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
MEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAW
HHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCH
EELPGLEEFEGDLDAYKADLMERLVKNSGDHHRRNVLNQYLEEVVAATSFDVPDALIAER
HHCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHELLHEQVESLARYGINMEQYLQIVGKTHDEAVQELLPRGEESLKSSLVVRKIVEAEGL
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
SVDESEINAEIERILNDFPDAQRGPARRRLEKELRPQVAGSLLDKKLQDRLVELATGNAA
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA