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The map label for this gene is rlmL [H]

Identifier: 159900362

GI number: 159900362

Start: 4827757

End: 4828632

Strand: Direct

Name: rlmL [H]

Synonym: Haur_3845

Alternate gene names: 159900362

Gene position: 4827757-4828632 (Clockwise)

Preceding gene: 159900361

Following gene: 159900363

Centisome position: 76.07

GC content: 51.26

Gene sequence:

>876_bases
ATGAAAACACTTTCACTACTAACATCCGATAATTGGCACGATTACGCCTTGCTCGATAGTGGCAATGGCCGCAAACTTGA
GCGTTTTGGCCCAGTCACCGTGATTCGCCCCGAAAGTGAAGCCTTGTGGCAACCCAAACTCGATGCCAAGGCATGGGAAG
CGGCTCATGCAATTTATGAATATCAAGGTAAGGGCGAAAATTGGCGTAAACTCAAGCCACACCCTGAAACATGGATGATG
AGCTACCAAGGCTTACGCTTCAAAGCCCAACTGACCCCGTTTCGCCATGTTGGGGTTTTCCCTGAACATGGTGCGCAATG
GGATTGGATTGCCGAGCAAATTAAGCGAAGCACCGAGCAACCACGAGTACTCAATTTGTTTGCATATACTGGCGTGGCCT
CGTTGGTTGCTGCGAAAGCTGGAGCCAAAGTAACCCACTTGGATGCTTCTAAAGCTTCGGTCGATTGGGCCAAGGAAAAT
CAAACAGCTTCGCAACTTGCGCCCGATTCAATTCGCTGGATTATTGATGATGCCTTAAAATTTGTACGGCGTGAAGCACG
GCGCGGCGCTCACTACGAAGGCATCATTATGGACCCCCCAGCTTTTGGGCGGGGCAGCCAAGGCCAAGTTTGGCAATTTG
CTGAATCATTTCCAGTGCTTTTGCAAGAATGTCGCACGATTCTGGCTCCCAAACCATTGTTCTTCTTGGTAACGACCTAC
GATACCCGCTCCTCGGCTTTGATGTTGGCCAACACGCTGGGCGATAGCTTGGCGGGTTTGCCAGGCGAGCTTGAGGCTGG
CGAACAAACCTTGCGCGAACAATCGGCAGGCCGTTTATTATCGACCTCGATTTATGCCCGCTGGAGCGCCAAATGA

Upstream 100 bases:

>100_bases
TTTAACCTATAAACACAAGTTAAGGTATCAGGTTTGGTAAGGTCAATGGGATAATTAGGGGTCACTGGCCCCTAACCCCC
GACCCCCGACCCCTAAAGTT

Downstream 100 bases:

>100_bases
GCCATGAATGCTGGCTGATTCGCCATGGCGAGAGCGTTGCCAATGCTGGCGAACGCACGCCCGATCCAGCTAGCATCCCC
TTGACGGCATTGGGTTGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKTLSLLTSDNWHDYALLDSGNGRKLERFGPVTVIRPESEALWQPKLDAKAWEAAHAIYEYQGKGENWRKLKPHPETWMM
SYQGLRFKAQLTPFRHVGVFPEHGAQWDWIAEQIKRSTEQPRVLNLFAYTGVASLVAAKAGAKVTHLDASKASVDWAKEN
QTASQLAPDSIRWIIDDALKFVRREARRGAHYEGIIMDPPAFGRGSQGQVWQFAESFPVLLQECRTILAPKPLFFLVTTY
DTRSSALMLANTLGDSLAGLPGELEAGEQTLREQSAGRLLSTSIYARWSAK

Sequences:

>Translated_291_residues
MKTLSLLTSDNWHDYALLDSGNGRKLERFGPVTVIRPESEALWQPKLDAKAWEAAHAIYEYQGKGENWRKLKPHPETWMM
SYQGLRFKAQLTPFRHVGVFPEHGAQWDWIAEQIKRSTEQPRVLNLFAYTGVASLVAAKAGAKVTHLDASKASVDWAKEN
QTASQLAPDSIRWIIDDALKFVRREARRGAHYEGIIMDPPAFGRGSQGQVWQFAESFPVLLQECRTILAPKPLFFLVTTY
DTRSSALMLANTLGDSLAGLPGELEAGEQTLREQSAGRLLSTSIYARWSAK
>Mature_291_residues
MKTLSLLTSDNWHDYALLDSGNGRKLERFGPVTVIRPESEALWQPKLDAKAWEAAHAIYEYQGKGENWRKLKPHPETWMM
SYQGLRFKAQLTPFRHVGVFPEHGAQWDWIAEQIKRSTEQPRVLNLFAYTGVASLVAAKAGAKVTHLDASKASVDWAKEN
QTASQLAPDSIRWIIDDALKFVRREARRGAHYEGIIMDPPAFGRGSQGQVWQFAESFPVLLQECRTILAPKPLFFLVTTY
DTRSSALMLANTLGDSLAGLPGELEAGEQTLREQSAGRLLSTSIYARWSAK

Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]

COG id: COG1092

COG function: function code R; Predicted SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR000241
- InterPro:   IPR017244
- InterPro:   IPR019614
- InterPro:   IPR004114 [H]

Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]

EC number: =2.1.1.173 [H]

Molecular weight: Translated: 32699; Mature: 32699

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLSLLTSDNWHDYALLDSGNGRKLERFGPVTVIRPESEALWQPKLDAKAWEAAHAIYE
CCCEEEEECCCCCCEEEEECCCCCEEHHHCCEEEECCCCHHHCCCCCCHHHHHHHHHHHH
YQGKGENWRKLKPHPETWMMSYQGLRFKAQLTPFRHVGVFPEHGAQWDWIAEQIKRSTEQ
CCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCHHEECCCCCCCCCHHHHHHHHHHCCCC
PRVLNLFAYTGVASLVAAKAGAKVTHLDASKASVDWAKENQTASQLAPDSIRWIIDDALK
CCEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCHHHCCCHHHHHHHHHHHH
FVRREARRGAHYEGIIMDPPAFGRGSQGQVWQFAESFPVLLQECRTILAPKPLFFLVTTY
HHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DTRSSALMLANTLGDSLAGLPGELEAGEQTLREQSAGRLLSTSIYARWSAK
CCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHEEEEECCC
>Mature Secondary Structure
MKTLSLLTSDNWHDYALLDSGNGRKLERFGPVTVIRPESEALWQPKLDAKAWEAAHAIYE
CCCEEEEECCCCCCEEEEECCCCCEEHHHCCEEEECCCCHHHCCCCCCHHHHHHHHHHHH
YQGKGENWRKLKPHPETWMMSYQGLRFKAQLTPFRHVGVFPEHGAQWDWIAEQIKRSTEQ
CCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCHHEECCCCCCCCCHHHHHHHHHHCCCC
PRVLNLFAYTGVASLVAAKAGAKVTHLDASKASVDWAKENQTASQLAPDSIRWIIDDALK
CCEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCHHHCCCHHHHHHHHHHHH
FVRREARRGAHYEGIIMDPPAFGRGSQGQVWQFAESFPVLLQECRTILAPKPLFFLVTTY
HHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DTRSSALMLANTLGDSLAGLPGELEAGEQTLREQSAGRLLSTSIYARWSAK
CCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA