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The map label for this gene is murC [H]

Identifier: 159900026

GI number: 159900026

Start: 4418723

End: 4420054

Strand: Reverse

Name: murC [H]

Synonym: Haur_3509

Alternate gene names: 159900026

Gene position: 4420054-4418723 (Counterclockwise)

Preceding gene: 159900027

Following gene: 159900025

Centisome position: 69.64

GC content: 55.11

Gene sequence:

>1332_bases
GTGCATACGCACATTGTTGGAATTGGTGGTTCAGGCATGAGTTCGATTGCGACGCTGCTGCTGGAGCGTGGCGATCAGGT
TTCTGGCTGCGATCGGGCGGCCAATGCGGCTACAACCCGCTTGGCTGACCATGGTGTTTCAGTCGAAATTGGCCATAGCG
CGAGCCATGTGCAGGGGATTGATCGGCTGTTGGTGACTTCGGCCTTGCCACTTGACCACATTGAGATTGTGGCGGCTCAC
CAAGCGGCGATTCCGGTGCTGACCCGCCATGATTTATGGCGTGAATGGAGCGCTGAACGCCCAACCCTTGCGGTTACTGG
AACGCATGGCAAAACCACCACTACCGCAATGTTAGCGGTTATTTTTAAGCATTGTGGCTATACGCCTGGCTTTTTGATTG
GAGCCGAAGTGCCAGCCTTAGGCGCGAGTGCCGCTTGGGGTCAAGGGCCATTGGTGCTCGAAGCCGATGAGTATGCCCGC
ACGTTTTTGGCCCTGAGTCCAGCAATTGGCATTATCACCAATCTCGATTGGGATCATGTGGATATTTATCCCAGCCAAGC
TGAGTATGATGCAGCTTTTCGTGAGTTTGCCATCAAGCCGAGCCTACAACATTTGGTGTTGTGCGGCGATGATCTGGGCA
CGCAACGGGTGCTTGCTGATGTGCCAGCGATTCGTTGTGGTTTGACTGAACATAACGATTGGCGAGCAACGGCGGTTCAA
GCTACGCCCGATGGCATGCTGTTTGAACTCATCAGCCCTGCTGCTGAGCCAATGACGGTGCAATTAGCGGTTTCTGGTGA
ACATAATGTGCGAAATGCTTTGTTGGCCTTAGCCGCTGCCCATTCCTATGGCATTGATTTAGCGGTAGCGGTGGCAGCGA
TTGCCCACTATCAAGGGGCAGCGCGACGCTTCGAGCCAAAAGGTCAAGTTGGTGCTGTACGCGTATTCGACGATTATGCA
CATCATCCGGTGGAAATTCGTGCGACCTTGGCGGCAGCTCGCAAGCGCTTTCCAGCGCAACGAATTGTGGCCTATTTTCA
GCCACATACCTTTAGCCGCTTGGAAGCGTTTCTAGCTGATTTTCAAACTGCTTTTGAGCAGGCGGATCTGGTGCGAATTG
GCGCGGTGTATGGGGCACGCGAAACCAGCAAGGGCGACCCAACCGCTCAAATCGTGGCTGGCATGCAACATCCCAATGCC
TTGGCAGTCGGCGATTTAGACCAAGCGTTTGAGCAATTGCTGCGCGATGTGCAGGCTGGCGATGTGGTGCTGACCTTGGG
AGCTGGCGATGGGGTTGTGGTTGGCGAGCGGTTGGTGGCGGCGCTGAGGTGA

Upstream 100 bases:

>100_bases
GCTGCTCGATGTTCGATGTTCTGAAAATCCTTGGGGACGCTGGGAATCGTCGATCTCAGCGTTTCTGCTGTTTTTATCTG
GCTTTTTTAAGGAGTCACTG

Downstream 100 bases:

>100_bases
TTCGATGATTGCTGATGCTGCCTATCGCCAATTTCATCGTGATGCGGCAGAGCGCTTGCGTCAACTCTACGCTGAACAGA
CAGGGCGGCCTGAAGGTTTG

Product: UDP-N-acetylmuramate--alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MHTHIVGIGGSGMSSIATLLLERGDQVSGCDRAANAATTRLADHGVSVEIGHSASHVQGIDRLLVTSALPLDHIEIVAAH
QAAIPVLTRHDLWREWSAERPTLAVTGTHGKTTTTAMLAVIFKHCGYTPGFLIGAEVPALGASAAWGQGPLVLEADEYAR
TFLALSPAIGIITNLDWDHVDIYPSQAEYDAAFREFAIKPSLQHLVLCGDDLGTQRVLADVPAIRCGLTEHNDWRATAVQ
ATPDGMLFELISPAAEPMTVQLAVSGEHNVRNALLALAAAHSYGIDLAVAVAAIAHYQGAARRFEPKGQVGAVRVFDDYA
HHPVEIRATLAAARKRFPAQRIVAYFQPHTFSRLEAFLADFQTAFEQADLVRIGAVYGARETSKGDPTAQIVAGMQHPNA
LAVGDLDQAFEQLLRDVQAGDVVLTLGAGDGVVVGERLVAALR

Sequences:

>Translated_443_residues
MHTHIVGIGGSGMSSIATLLLERGDQVSGCDRAANAATTRLADHGVSVEIGHSASHVQGIDRLLVTSALPLDHIEIVAAH
QAAIPVLTRHDLWREWSAERPTLAVTGTHGKTTTTAMLAVIFKHCGYTPGFLIGAEVPALGASAAWGQGPLVLEADEYAR
TFLALSPAIGIITNLDWDHVDIYPSQAEYDAAFREFAIKPSLQHLVLCGDDLGTQRVLADVPAIRCGLTEHNDWRATAVQ
ATPDGMLFELISPAAEPMTVQLAVSGEHNVRNALLALAAAHSYGIDLAVAVAAIAHYQGAARRFEPKGQVGAVRVFDDYA
HHPVEIRATLAAARKRFPAQRIVAYFQPHTFSRLEAFLADFQTAFEQADLVRIGAVYGARETSKGDPTAQIVAGMQHPNA
LAVGDLDQAFEQLLRDVQAGDVVLTLGAGDGVVVGERLVAALR
>Mature_443_residues
MHTHIVGIGGSGMSSIATLLLERGDQVSGCDRAANAATTRLADHGVSVEIGHSASHVQGIDRLLVTSALPLDHIEIVAAH
QAAIPVLTRHDLWREWSAERPTLAVTGTHGKTTTTAMLAVIFKHCGYTPGFLIGAEVPALGASAAWGQGPLVLEADEYAR
TFLALSPAIGIITNLDWDHVDIYPSQAEYDAAFREFAIKPSLQHLVLCGDDLGTQRVLADVPAIRCGLTEHNDWRATAVQ
ATPDGMLFELISPAAEPMTVQLAVSGEHNVRNALLALAAAHSYGIDLAVAVAAIAHYQGAARRFEPKGQVGAVRVFDDYA
HHPVEIRATLAAARKRFPAQRIVAYFQPHTFSRLEAFLADFQTAFEQADLVRIGAVYGARETSKGDPTAQIVAGMQHPNA
LAVGDLDQAFEQLLRDVQAGDVVLTLGAGDGVVVGERLVAALR

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=447, Percent_Identity=36.0178970917226, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1790680, Length=461, Percent_Identity=28.6334056399132, Blast_Score=162, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 47184; Mature: 47184

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTHIVGIGGSGMSSIATLLLERGDQVSGCDRAANAATTRLADHGVSVEIGHSASHVQGI
CCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHH
DRLLVTSALPLDHIEIVAAHQAAIPVLTRHDLWREWSAERPTLAVTGTHGKTTTTAMLAV
HHHHHHHCCCCCHHEEEEHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
IFKHCGYTPGFLIGAEVPALGASAAWGQGPLVLEADEYARTFLALSPAIGIITNLDWDHV
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHHEECCCCCCE
DIYPSQAEYDAAFREFAIKPSLQHLVLCGDDLGTQRVLADVPAIRCGLTEHNDWRATAVQ
EECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCHHEECCCCCCCCEEEEEE
ATPDGMLFELISPAAEPMTVQLAVSGEHNVRNALLALAAAHSYGIDLAVAVAAIAHYQGA
ECCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARRFEPKGQVGAVRVFDDYAHHPVEIRATLAAARKRFPAQRIVAYFQPHTFSRLEAFLAD
HHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
FQTAFEQADLVRIGAVYGARETSKGDPTAQIVAGMQHPNALAVGDLDQAFEQLLRDVQAG
HHHHHHHCCEEEEEHHHCCCCCCCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCC
DVVLTLGAGDGVVVGERLVAALR
CEEEEEECCCCEEHHHHHHHHCC
>Mature Secondary Structure
MHTHIVGIGGSGMSSIATLLLERGDQVSGCDRAANAATTRLADHGVSVEIGHSASHVQGI
CCEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHH
DRLLVTSALPLDHIEIVAAHQAAIPVLTRHDLWREWSAERPTLAVTGTHGKTTTTAMLAV
HHHHHHHCCCCCHHEEEEHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
IFKHCGYTPGFLIGAEVPALGASAAWGQGPLVLEADEYARTFLALSPAIGIITNLDWDHV
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHHEECCCCCCE
DIYPSQAEYDAAFREFAIKPSLQHLVLCGDDLGTQRVLADVPAIRCGLTEHNDWRATAVQ
EECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCHHEECCCCCCCCEEEEEE
ATPDGMLFELISPAAEPMTVQLAVSGEHNVRNALLALAAAHSYGIDLAVAVAAIAHYQGA
ECCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARRFEPKGQVGAVRVFDDYAHHPVEIRATLAAARKRFPAQRIVAYFQPHTFSRLEAFLAD
HHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
FQTAFEQADLVRIGAVYGARETSKGDPTAQIVAGMQHPNALAVGDLDQAFEQLLRDVQAG
HHHHHHHCCEEEEEHHHCCCCCCCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCC
DVVLTLGAGDGVVVGERLVAALR
CEEEEEECCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA