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The map label for this gene is 159899773

Identifier: 159899773

GI number: 159899773

Start: 4117233

End: 4118333

Strand: Reverse

Name: 159899773

Synonym: Haur_3255

Alternate gene names: NA

Gene position: 4118333-4117233 (Counterclockwise)

Preceding gene: 159899774

Following gene: 159899772

Centisome position: 64.89

GC content: 49.77

Gene sequence:

>1101_bases
ATGCGTTACGTTAACCCCTCGCCAACGATTTCAAACGTTGTCTGCAATCAATTATCAATTGTGCTCTTGGTGGGCGTAAT
GTTGGGAACATTAACTGCCTGTAGCACTTCAAGTTCTAATCCGTTGCCTACAATTGGCATTGATGTCGGGCCAGGGGTTA
ACTTTCGCGGCGATATTGTGGCGCTCCAGTTTCTGCCCAACCAACAGCTTTTGGTGGGGGTTGGCTACGATGGGGTTTAT
CGTTGGAAGCTTGCTACGAGCACAATTGAACAAACCCTTGCCGCCAAACAAATTTACTTGGCCTTTACAGCTTCAGGGCC
ATTGGTTGTAAGCACTGATCGTAAAACGCTGACGACTTGGAATAGCACTGATGGCCAAAAAATTCTGGCGTGGAATGCCA
AACCATTGCAACTGCCTAGCCAAACCACTGCCTTTGAAGTCAGTGCCCTCGCAATCACACCTGATCAGCAGCAAATTATT
GCAGCCTACAACAAAGGTAGCATGCTCCAAGCTTGGAACGTGGCGACTGGTGCGGCAACAACGACCTTTGGTGCTCCGGC
CAAAACTGGCTCAATTGTTGAAATTGCGCTCAGCCCTGATGGTCAATTACTGGCCAGCAACGATTTTAGTGGCGTAGTGC
AGATTTGGGATGTAGTGAGTGGTCAGCAATTACATTCATTCAAAGAAGCCAGCCTCAACTATCAACCAGGCAAATTGGCT
TGGAGCCACGATGGCAAATGGCTGGCAGCCAGTAGCGGCGATAAAAACGGCGGCGGAGTCGCGATTTGGGATACCAGTTC
ATGGTCAATCTATGCCACGCATCGCAGCAGTGAGCACCAATTTGCTGGTTTGGCCTTTCATCCAACCGCTCCAACGTTGG
CGATTGGCAATAGTAGTGGCTTGATCGAGTTGTACGATCTGACCAGCAAACAAGTCAGCAACAGCCTCAAAGGCCATGCC
GAGCGGGTTACAACCTTGGCATGGAATGCTGATGGCAGCCAATTGGCCTCAGGCGGCAAAGAACCATTTGTCCTGATTTG
GGATAGTACAAGCCTGACCGAGCAGCAACGTTTGGTTTTGCCAGCTACACCATTACAGTAA

Upstream 100 bases:

>100_bases
CACGATCAAGACCAAAACCTCGATTTACATATCTGCGAAGATCAAAGTTGGGTTTGGTTTGAAGTCAGTTCGCTAATTGT
TTTAGAAGGAAAATAGGTTC

Downstream 100 bases:

>100_bases
TTGATTCAGTGATTCTAGTTTGAAAACCCTTGTCAATGTAGGTTGATAAGGGTTTTTGGTGCGTTTGAAAAGCAGATCGA
GGCAGATGATCAAACAACGA

Product: WD-40 repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRYVNPSPTISNVVCNQLSIVLLVGVMLGTLTACSTSSSNPLPTIGIDVGPGVNFRGDIVALQFLPNQQLLVGVGYDGVY
RWKLATSTIEQTLAAKQIYLAFTASGPLVVSTDRKTLTTWNSTDGQKILAWNAKPLQLPSQTTAFEVSALAITPDQQQII
AAYNKGSMLQAWNVATGAATTTFGAPAKTGSIVEIALSPDGQLLASNDFSGVVQIWDVVSGQQLHSFKEASLNYQPGKLA
WSHDGKWLAASSGDKNGGGVAIWDTSSWSIYATHRSSEHQFAGLAFHPTAPTLAIGNSSGLIELYDLTSKQVSNSLKGHA
ERVTTLAWNADGSQLASGGKEPFVLIWDSTSLTEQQRLVLPATPLQ

Sequences:

>Translated_366_residues
MRYVNPSPTISNVVCNQLSIVLLVGVMLGTLTACSTSSSNPLPTIGIDVGPGVNFRGDIVALQFLPNQQLLVGVGYDGVY
RWKLATSTIEQTLAAKQIYLAFTASGPLVVSTDRKTLTTWNSTDGQKILAWNAKPLQLPSQTTAFEVSALAITPDQQQII
AAYNKGSMLQAWNVATGAATTTFGAPAKTGSIVEIALSPDGQLLASNDFSGVVQIWDVVSGQQLHSFKEASLNYQPGKLA
WSHDGKWLAASSGDKNGGGVAIWDTSSWSIYATHRSSEHQFAGLAFHPTAPTLAIGNSSGLIELYDLTSKQVSNSLKGHA
ERVTTLAWNADGSQLASGGKEPFVLIWDSTSLTEQQRLVLPATPLQ
>Mature_366_residues
MRYVNPSPTISNVVCNQLSIVLLVGVMLGTLTACSTSSSNPLPTIGIDVGPGVNFRGDIVALQFLPNQQLLVGVGYDGVY
RWKLATSTIEQTLAAKQIYLAFTASGPLVVSTDRKTLTTWNSTDGQKILAWNAKPLQLPSQTTAFEVSALAITPDQQQII
AAYNKGSMLQAWNVATGAATTTFGAPAKTGSIVEIALSPDGQLLASNDFSGVVQIWDVVSGQQLHSFKEASLNYQPGKLA
WSHDGKWLAASSGDKNGGGVAIWDTSSWSIYATHRSSEHQFAGLAFHPTAPTLAIGNSSGLIELYDLTSKQVSNSLKGHA
ERVTTLAWNADGSQLASGGKEPFVLIWDSTSLTEQQRLVLPATPLQ

Specific function: Unknown

COG id: COG2319

COG function: function code R; FOG: WD40 repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 16 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI16554629, Length=292, Percent_Identity=23.6301369863014, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI16554627, Length=292, Percent_Identity=23.6301369863014, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI239787764, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI239787760, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI239787754, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI113865883, Length=212, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13376840, Length=274, Percent_Identity=21.8978102189781, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568701, Length=180, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864654, Length=292, Percent_Identity=24.3150684931507, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356075, Length=200, Percent_Identity=27.5, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24663767, Length=182, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646
- InterPro:   IPR020472
- InterPro:   IPR007111
- InterPro:   IPR011047
- InterPro:   IPR015943
- InterPro:   IPR001680
- InterPro:   IPR011046
- InterPro:   IPR019782
- InterPro:   IPR019775
- InterPro:   IPR017986
- InterPro:   IPR019781 [H]

Pfam domain/function: PF00805 Pentapeptide; PF00400 WD40 [H]

EC number: NA

Molecular weight: Translated: 38888; Mature: 38888

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50082 WD_REPEATS_2 ; PS50294 WD_REPEATS_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVNPSPTISNVVCNQLSIVLLVGVMLGTLTACSTSSSNPLPTIGIDVGPGVNFRGDIV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEE
ALQFLPNQQLLVGVGYDGVYRWKLATSTIEQTLAAKQIYLAFTASGPLVVSTDRKTLTTW
EEEECCCCEEEEEECCCCEEEEEEEHHHHHHHHHEEEEEEEEECCCCEEEECCCCEEEEE
NSTDGQKILAWNAKPLQLPSQTTAFEVSALAITPDQQQIIAAYNKGSMLQAWNVATGAAT
CCCCCCEEEEECCCCEECCCCCCEEEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCE
TTFGAPAKTGSIVEIALSPDGQLLASNDFSGVVQIWDVVSGQQLHSFKEASLNYQPGKLA
EECCCCCCCCCEEEEEECCCCCEEECCCCCCHHEEEHHHCCHHHHHHHHHCCCCCCCEEE
WSHDGKWLAASSGDKNGGGVAIWDTSSWSIYATHRSSEHQFAGLAFHPTAPTLAIGNSSG
EECCCCEEEECCCCCCCCEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEECCCCC
LIELYDLTSKQVSNSLKGHAERVTTLAWNADGSQLASGGKEPFVLIWDSTSLTEQQRLVL
EEEEEECCHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCCCEEEEECCCCCCCCCEEEE
PATPLQ
CCCCCC
>Mature Secondary Structure
MRYVNPSPTISNVVCNQLSIVLLVGVMLGTLTACSTSSSNPLPTIGIDVGPGVNFRGDIV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEE
ALQFLPNQQLLVGVGYDGVYRWKLATSTIEQTLAAKQIYLAFTASGPLVVSTDRKTLTTW
EEEECCCCEEEEEECCCCEEEEEEEHHHHHHHHHEEEEEEEEECCCCEEEECCCCEEEEE
NSTDGQKILAWNAKPLQLPSQTTAFEVSALAITPDQQQIIAAYNKGSMLQAWNVATGAAT
CCCCCCEEEEECCCCEECCCCCCEEEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCE
TTFGAPAKTGSIVEIALSPDGQLLASNDFSGVVQIWDVVSGQQLHSFKEASLNYQPGKLA
EECCCCCCCCCEEEEEECCCCCEEECCCCCCHHEEEHHHCCHHHHHHHHHCCCCCCCEEE
WSHDGKWLAASSGDKNGGGVAIWDTSSWSIYATHRSSEHQFAGLAFHPTAPTLAIGNSSG
EECCCCEEEECCCCCCCCEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEECCCCC
LIELYDLTSKQVSNSLKGHAERVTTLAWNADGSQLASGGKEPFVLIWDSTSLTEQQRLVL
EEEEEECCHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCCCEEEEECCCCCCCCCEEEE
PATPLQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]