Click here to switch to the map view.

The map label for this gene is nuoN1

Identifier: 159899729

GI number: 159899729

Start: 4059814

End: 4061289

Strand: Reverse

Name: nuoN1

Synonym: Haur_3211

Alternate gene names: 159899729

Gene position: 4061289-4059814 (Counterclockwise)

Preceding gene: 159899730

Following gene: 159899728

Centisome position: 63.99

GC content: 50.88

Gene sequence:

>1476_bases
ATGAATGATTTAACATTTATCACGCCGGAGATTAACTGGACAGTCTTAGGCATGCCAGCATTCCTGATGATTTGGGCGAT
GTTGGTGTTGATTGTCGATATGTTCACCTCGGATCGGCGGGTTTTGCTCACGTTGAGCCTGATTGGGCTTGGCGTGACGG
CAGCGCTGGGTGCGCTGGATTATGGCTCAACTATCTCAGGCTTCTCAGACATGTTGGTGTTTGACAAGTTTGGGGTATTG
GTAAATTGGATTTTGCTGGCGGGCACAGCCTTGACCTTGCTGATTGCCTTTGATTACATGCCACGCCAAAATCTCAGCCA
AGGCGAATTTTATCCCTTGGTCTTGTTTGCAACCTCTGGGATGTTGTTCTTGGTTCAATCAACTGACCTCGTAACGATTT
TCATTGGGGTTGAAACGCTCTCGATTGCGTTATATGTGCTAACCGGCTTTGCCGTGCCGCAGTTCAAATCGGGCGAAGCT
GCGATTAAATATCTGTTGCTTGGCGGTTTTGCGGCTGGCTTTTTGGTCTATGGCATTGCCTTGATTTATGGCATGACCGG
CAAAACCAACCTAGCCCAAATTGCCAACGAATTGAGCACTTGGCAAAGCACTGGCAAAGCACTTGATGATCCAATTTTGT
TGGCTGGGGTTGGCTTTGTACTGATCGCCTTGGGCTTCAAGGTTTCAATGTTCCCCTTCCACGCTTGGACACCTGACGTT
TACGAAGGTGCGCCTACGCCAGTCACCGCCTATATGTCGGTTGCAACTAAGGGTGCAGCGTTTGCAGCAATGTTGCGTTT
CTTGAATGTAGCATTTCCTGCACTCAAACCTGAGTGGCAATTGCTGTTTGGCTTATTTGCCGCTGCAACCATGGCCTATG
GCAATATCGTGGCAGTTGCGCAAACCAACCTCAAGCGGATGTTGGCCTATTCGTCGATTGCCCACGCTGGCTATATGTTG
CTGGGCGTGTTGGCAGCCAGCGAAAAAGGCATCAGCGCCTTCACGGTTTACCTGTTGGCCTACACCTTAACCAACCTTGG
CGCGTTCGCTGTGCTGATTGCTTTGGAAAATCGCGGTATGCCCGTATTTGAATTGAGCGATTTACGTGGTTTGGGCAAGC
GTAGCCCATTGTTGGCGCTCGCGATGACCGTGTTTATGTTCTCGTTGGCGGGCGTGCCACCAACAGCCGGATTTGCCAGC
AAGTTTGGCATTTTCCGCGCCGCTTGGGATGCCAACCTCGATTATCTGGCGATTATCGGGGTGGTTACCAGTGTGATTTC
GGCATTCTTCTACTTGCGGGTGATTGTGACGATGTGGATGCGCGATACCGAAGCCACCGAGCCACAACCAACCTATGCCA
CGGCCTCGCTCTCGTTGGGCGTGATCGTCGCCGTAATTGGGATTATCGCTGTTGGGATTTTGCCCAATATCTTTACCGAT
TTGGCCAAAGCTCTAGTTCTGACCGTCGCTCCCTAA

Upstream 100 bases:

>100_bases
CTTTACTCGCCCAATGGAAACAACGATCAAGGCGCTTGAAGCCTTCGTTGCTAATGCTGCGCCACTGATTGCTGGCCAAT
AAGACGGAGCGTGAGTTCGA

Downstream 100 bases:

>100_bases
GTCAGTTTGAGTCCCTCACCCCCTAGCCCCCTCTCCCGCCCAGCAGGCGAGGGGGAACCATCATCATGCTCCCTCACGAA
CCTACGGGTTTATGGGGGAG

Product: proton-translocating NADH-quinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N 1; NDH-1 subunit N 1

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNDLTFITPEINWTVLGMPAFLMIWAMLVLIVDMFTSDRRVLLTLSLIGLGVTAALGALDYGSTISGFSDMLVFDKFGVL
VNWILLAGTALTLLIAFDYMPRQNLSQGEFYPLVLFATSGMLFLVQSTDLVTIFIGVETLSIALYVLTGFAVPQFKSGEA
AIKYLLLGGFAAGFLVYGIALIYGMTGKTNLAQIANELSTWQSTGKALDDPILLAGVGFVLIALGFKVSMFPFHAWTPDV
YEGAPTPVTAYMSVATKGAAFAAMLRFLNVAFPALKPEWQLLFGLFAAATMAYGNIVAVAQTNLKRMLAYSSIAHAGYML
LGVLAASEKGISAFTVYLLAYTLTNLGAFAVLIALENRGMPVFELSDLRGLGKRSPLLALAMTVFMFSLAGVPPTAGFAS
KFGIFRAAWDANLDYLAIIGVVTSVISAFFYLRVIVTMWMRDTEATEPQPTYATASLSLGVIVAVIGIIAVGILPNIFTD
LAKALVLTVAP

Sequences:

>Translated_491_residues
MNDLTFITPEINWTVLGMPAFLMIWAMLVLIVDMFTSDRRVLLTLSLIGLGVTAALGALDYGSTISGFSDMLVFDKFGVL
VNWILLAGTALTLLIAFDYMPRQNLSQGEFYPLVLFATSGMLFLVQSTDLVTIFIGVETLSIALYVLTGFAVPQFKSGEA
AIKYLLLGGFAAGFLVYGIALIYGMTGKTNLAQIANELSTWQSTGKALDDPILLAGVGFVLIALGFKVSMFPFHAWTPDV
YEGAPTPVTAYMSVATKGAAFAAMLRFLNVAFPALKPEWQLLFGLFAAATMAYGNIVAVAQTNLKRMLAYSSIAHAGYML
LGVLAASEKGISAFTVYLLAYTLTNLGAFAVLIALENRGMPVFELSDLRGLGKRSPLLALAMTVFMFSLAGVPPTAGFAS
KFGIFRAAWDANLDYLAIIGVVTSVISAFFYLRVIVTMWMRDTEATEPQPTYATASLSLGVIVAVIGIIAVGILPNIFTD
LAKALVLTVAP
>Mature_491_residues
MNDLTFITPEINWTVLGMPAFLMIWAMLVLIVDMFTSDRRVLLTLSLIGLGVTAALGALDYGSTISGFSDMLVFDKFGVL
VNWILLAGTALTLLIAFDYMPRQNLSQGEFYPLVLFATSGMLFLVQSTDLVTIFIGVETLSIALYVLTGFAVPQFKSGEA
AIKYLLLGGFAAGFLVYGIALIYGMTGKTNLAQIANELSTWQSTGKALDDPILLAGVGFVLIALGFKVSMFPFHAWTPDV
YEGAPTPVTAYMSVATKGAAFAAMLRFLNVAFPALKPEWQLLFGLFAAATMAYGNIVAVAQTNLKRMLAYSSIAHAGYML
LGVLAASEKGISAFTVYLLAYTLTNLGAFAVLIALENRGMPVFELSDLRGLGKRSPLLALAMTVFMFSLAGVPPTAGFAS
KFGIFRAAWDANLDYLAIIGVVTSVISAFFYLRVIVTMWMRDTEATEPQPTYATASLSLGVIVAVIGIIAVGILPNIFTD
LAKALVLTVAP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=480, Percent_Identity=33.9583333333333, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1788831, Length=329, Percent_Identity=28.2674772036474, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788614, Length=400, Percent_Identity=26.25, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788613, Length=225, Percent_Identity=28.4444444444444, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788829, Length=451, Percent_Identity=25.2771618625277, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON1_HERA2 (A9B6Y0)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545976.1
- GeneID:   5735079
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3211
- HOGENOM:   HBG747830
- OMA:   LMFFSEP
- ProtClustDB:   CLSK974060
- BioCyc:   HAUR316274:HAUR_3211-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 52596; Mature: 52596

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x155c0398)-; HASH(0x1566cae0)-; HASH(0x179284d0)-; HASH(0x1566c7f8)-; HASH(0x17af8288)-; HASH(0x1566c7ec)-; HASH(0x17af806c)-; HASH(0x1566c9cc)-; HASH(0x17541be0)-; HASH(0x1566cc0c)-; HASH(0x17494040)-; HASH(0x17af8120)-; HASH(0x17197588)-; HASH(0x17af8168)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLTFITPEINWTVLGMPAFLMIWAMLVLIVDMFTSDRRVLLTLSLIGLGVTAALGALD
CCCCEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCC
YGSTISGFSDMLVFDKFGVLVNWILLAGTALTLLIAFDYMPRQNLSQGEFYPLVLFATSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
MLFLVQSTDLVTIFIGVETLSIALYVLTGFAVPQFKSGEAAIKYLLLGGFAAGFLVYGIA
EEEEEECCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LIYGMTGKTNLAQIANELSTWQSTGKALDDPILLAGVGFVLIALGFKVSMFPFHAWTPDV
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHEEEEEECCCCHH
YEGAPTPVTAYMSVATKGAAFAAMLRFLNVAFPALKPEWQLLFGLFAAATMAYGNIVAVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEE
QTNLKRMLAYSSIAHAGYMLLGVLAASEKGISAFTVYLLAYTLTNLGAFAVLIALENRGM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
PVFELSDLRGLGKRSPLLALAMTVFMFSLAGVPPTAGFASKFGIFRAAWDANLDYLAIIG
CEEEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCHHHHHHH
VVTSVISAFFYLRVIVTMWMRDTEATEPQPTYATASLSLGVIVAVIGIIAVGILPNIFTD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKALVLTVAP
HHHHHHHCCCH
>Mature Secondary Structure
MNDLTFITPEINWTVLGMPAFLMIWAMLVLIVDMFTSDRRVLLTLSLIGLGVTAALGALD
CCCCEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCC
YGSTISGFSDMLVFDKFGVLVNWILLAGTALTLLIAFDYMPRQNLSQGEFYPLVLFATSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
MLFLVQSTDLVTIFIGVETLSIALYVLTGFAVPQFKSGEAAIKYLLLGGFAAGFLVYGIA
EEEEEECCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LIYGMTGKTNLAQIANELSTWQSTGKALDDPILLAGVGFVLIALGFKVSMFPFHAWTPDV
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHEEEEEECCCCHH
YEGAPTPVTAYMSVATKGAAFAAMLRFLNVAFPALKPEWQLLFGLFAAATMAYGNIVAVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEE
QTNLKRMLAYSSIAHAGYMLLGVLAASEKGISAFTVYLLAYTLTNLGAFAVLIALENRGM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
PVFELSDLRGLGKRSPLLALAMTVFMFSLAGVPPTAGFASKFGIFRAAWDANLDYLAIIG
CEEEEHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCHHHHHHH
VVTSVISAFFYLRVIVTMWMRDTEATEPQPTYATASLSLGVIVAVIGIIAVGILPNIFTD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKALVLTVAP
HHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA