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The map label for this gene is merR1 [H]

Identifier: 159899728

GI number: 159899728

Start: 4058979

End: 4059389

Strand: Reverse

Name: merR1 [H]

Synonym: Haur_3210

Alternate gene names: 159899728

Gene position: 4059389-4058979 (Counterclockwise)

Preceding gene: 159899729

Following gene: 159899727

Centisome position: 63.96

GC content: 49.64

Gene sequence:

>411_bases
ATGCAAATTGGCCAAGTAGCTCGCCGTTGTGGCGTGAGTGTGCAAACGGTACGCTTATATGAACGAATGGGCTTGATCGA
AACCGCCCAACGCCGTGAATCAGGCTATCGCGATTATTCAAACACGGTGGTTGCGCGAATTTTGGCAATCAAGCAAGGTC
AAGCATTGGGCTTTAGCTTGCGCGAAATGGGCATGTTTCTGCAACTCAGCCCGCAAAATACCGAGCAAGCCTTGATTCAG
CAATTTGTTGAGCAAAAAGTCCAGCAGATTGATCAGACGGTTCAACAGTTTCAGCGTTTGCGCCAAGCCTTGCATGAATT
TGCCGCTCGTTCCGCTGATGATCTGCGTGAATGCCCTGTTATTTACGCTTTGGCCGAAATGGCCTGCGCACAAGGAGTTT
CTGATGCTTAG

Upstream 100 bases:

>100_bases
TTTGATTTTTGCCTTCTGCCTTTTGATTTTAGTAAAAACTTGGGCTTGACTCTATAGCATAGTATAGGGTTTATGCTAAG
CAGCAGAAAGGAATTGAGCG

Downstream 100 bases:

>100_bases
AACAATTCGTAGTTTACGTTGGTTTGGTTGGTATGCGGTGAGCACTGGGCTTTTGGCAGCACTCGCGCCAAATCTGCTCT
TGAGTGTATTTGGCATGCCG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MQIGQVARRCGVSVQTVRLYERMGLIETAQRRESGYRDYSNTVVARILAIKQGQALGFSLREMGMFLQLSPQNTEQALIQ
QFVEQKVQQIDQTVQQFQRLRQALHEFAARSADDLRECPVIYALAEMACAQGVSDA

Sequences:

>Translated_136_residues
MQIGQVARRCGVSVQTVRLYERMGLIETAQRRESGYRDYSNTVVARILAIKQGQALGFSLREMGMFLQLSPQNTEQALIQ
QFVEQKVQQIDQTVQQFQRLRQALHEFAARSADDLRECPVIYALAEMACAQGVSDA
>Mature_136_residues
MQIGQVARRCGVSVQTVRLYERMGLIETAQRRESGYRDYSNTVVARILAIKQGQALGFSLREMGMFLQLSPQNTEQALIQ
QFVEQKVQQIDQTVQQFQRLRQALHEFAARSADDLRECPVIYALAEMACAQGVSDA

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=31.25, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011794
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15397; Mature: 15397

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIGQVARRCGVSVQTVRLYERMGLIETAQRRESGYRDYSNTVVARILAIKQGQALGFSL
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHH
REMGMFLQLSPQNTEQALIQQFVEQKVQQIDQTVQQFQRLRQALHEFAARSADDLRECPV
HHHCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IYALAEMACAQGVSDA
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQIGQVARRCGVSVQTVRLYERMGLIETAQRRESGYRDYSNTVVARILAIKQGQALGFSL
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHH
REMGMFLQLSPQNTEQALIQQFVEQKVQQIDQTVQQFQRLRQALHEFAARSADDLRECPV
HHHCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IYALAEMACAQGVSDA
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536669; 10559175; 2492496; 2305262 [H]