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The map label for this gene is lepB [H]

Identifier: 159899545

GI number: 159899545

Start: 3821582

End: 3822370

Strand: Reverse

Name: lepB [H]

Synonym: Haur_3026

Alternate gene names: 159899545

Gene position: 3822370-3821582 (Counterclockwise)

Preceding gene: 159899560

Following gene: 159899544

Centisome position: 60.23

GC content: 48.54

Gene sequence:

>789_bases
ATGAGTTCAACACCGCTACGGGATCGGCTTGAACAAGCTGCTCAACATGATCCAAATCCATTAAAACCAACCAGGCTTGA
GCCAGCTCCACCACCAGAAGAACCGCTGGATTTAGAGGAAGCGGCTGCTGAAACCGTTCCCCAACGTCGCGGCTGGTCGG
TCGTCAAAGAGATTATCGAGACGGTCGTTTTTGTGCTTTTGGTCTTTTTTATTGTGCGTGGCTTGTTGCAGAATTTTCGC
ATCGAAGGTTCGAGCATGTTTCCAACCATGCACGATCAGCAATATATTTTGGTTAATAAAGCTTTATATATGCACTTTGA
CCTAAATGCGCCGCTGCGACTCTTGCCAGGCCGAGGCGATCTTGAGCAAAATGTGGTTTATCCCTTCCGTAAGCCGCAAC
AAGGCGATATTGTCGTATTCTTGGCTCCAGAGTCGGCCCATGACGAGCCTAACAAAGATTACATTAAACGGGTGATTGGG
ATCGAGGGCGATAAAGTTACCTTGCTCGATGGTCAAGTCTATGTCAACGACCAACTCCTCGACGAATCGGAATATCTTGA
TGCTGGTACGCAAACCAGTTGTAAAGGCTATGCCTCTACCTGTAGCGTCGATATTCCAGCTGGCCATGTTTTTGTGATGG
GTGATAATCGCAATAACAGCAGCGACTCACGCGAGTGGGGGCCATTGCCCTTAGATAATGTGATTGGCAAGGCTTGGCTT
TCGTATTGGCCTAAAGAAGATTGGGGTGTTGTGCAAACGCCCAGTTATGCAGCACCAACGGGCCAATGA

Upstream 100 bases:

>100_bases
TTTTGGTCAATTAAAATCAAGACTTCTAGGGCAGGTTTGGCCAAAGTTGGTATGCTATAATGCCGCGCAGCGACATAATT
CAGGGTGTAAGGATAATTCA

Downstream 100 bases:

>100_bases
ACGATTTCGAGCAATCCGAAGTAAAAACCACCCGCTTGGCGCTTGATCAGACTCAACCGCTGCCAGTTGCTGCGCCAAGC
GCCGAAGAAATTGCTTGGTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSSTPLRDRLEQAAQHDPNPLKPTRLEPAPPPEEPLDLEEAAAETVPQRRGWSVVKEIIETVVFVLLVFFIVRGLLQNFR
IEGSSMFPTMHDQQYILVNKALYMHFDLNAPLRLLPGRGDLEQNVVYPFRKPQQGDIVVFLAPESAHDEPNKDYIKRVIG
IEGDKVTLLDGQVYVNDQLLDESEYLDAGTQTSCKGYASTCSVDIPAGHVFVMGDNRNNSSDSREWGPLPLDNVIGKAWL
SYWPKEDWGVVQTPSYAAPTGQ

Sequences:

>Translated_262_residues
MSSTPLRDRLEQAAQHDPNPLKPTRLEPAPPPEEPLDLEEAAAETVPQRRGWSVVKEIIETVVFVLLVFFIVRGLLQNFR
IEGSSMFPTMHDQQYILVNKALYMHFDLNAPLRLLPGRGDLEQNVVYPFRKPQQGDIVVFLAPESAHDEPNKDYIKRVIG
IEGDKVTLLDGQVYVNDQLLDESEYLDAGTQTSCKGYASTCSVDIPAGHVFVMGDNRNNSSDSREWGPLPLDNVIGKAWL
SYWPKEDWGVVQTPSYAAPTGQ
>Mature_261_residues
SSTPLRDRLEQAAQHDPNPLKPTRLEPAPPPEEPLDLEEAAAETVPQRRGWSVVKEIIETVVFVLLVFFIVRGLLQNFRI
EGSSMFPTMHDQQYILVNKALYMHFDLNAPLRLLPGRGDLEQNVVYPFRKPQQGDIVVFLAPESAHDEPNKDYIKRVIGI
EGDKVTLLDGQVYVNDQLLDESEYLDAGTQTSCKGYASTCSVDIPAGHVFVMGDNRNNSSDSREWGPLPLDNVIGKAWLS
YWPKEDWGVVQTPSYAAPTGQ

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29388; Mature: 29257

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTPLRDRLEQAAQHDPNPLKPTRLEPAPPPEEPLDLEEAAAETVPQRRGWSVVKEIIE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
TVVFVLLVFFIVRGLLQNFRIEGSSMFPTMHDQQYILVNKALYMHFDLNAPLRLLPGRGD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCEEEECCCCC
LEQNVVYPFRKPQQGDIVVFLAPESAHDEPNKDYIKRVIGIEGDKVTLLDGQVYVNDQLL
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEECCEEEECHHHC
DESEYLDAGTQTSCKGYASTCSVDIPAGHVFVMGDNRNNSSDSREWGPLPLDNVIGKAWL
CCHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
SYWPKEDWGVVQTPSYAAPTGQ
HHCCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
SSTPLRDRLEQAAQHDPNPLKPTRLEPAPPPEEPLDLEEAAAETVPQRRGWSVVKEIIE
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
TVVFVLLVFFIVRGLLQNFRIEGSSMFPTMHDQQYILVNKALYMHFDLNAPLRLLPGRGD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCEEEECCCCC
LEQNVVYPFRKPQQGDIVVFLAPESAHDEPNKDYIKRVIGIEGDKVTLLDGQVYVNDQLL
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEECCEEEECHHHC
DESEYLDAGTQTSCKGYASTCSVDIPAGHVFVMGDNRNNSSDSREWGPLPLDNVIGKAWL
CCHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
SYWPKEDWGVVQTPSYAAPTGQ
HHCCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]