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The map label for this gene is lepB1 [H]

Identifier: 159899544

GI number: 159899544

Start: 3820839

End: 3821585

Strand: Reverse

Name: lepB1 [H]

Synonym: Haur_3025

Alternate gene names: 159899544

Gene position: 3821585-3820839 (Counterclockwise)

Preceding gene: 159899545

Following gene: 159899538

Centisome position: 60.21

GC content: 49.93

Gene sequence:

>747_bases
ATGAACGATTTCGAGCAATCCGAAGTAAAAACCACCCGCTTGGCGCTTGATCAGACTCAACCGCTGCCAGTTGCTGCGCC
AAGCGCCGAAGAAATTGCTTGGTTGGAGCAATCACAAGCGCCATTGCCTACCCCGCCTACCCCAACTCCAGCACTGCAAC
GGCCACGCTTACGCCGTTCATGGCACATGCTGGCTAGCTTGATTTTGAGTTTTTTGATTCTGCGCAGCTTGATTCAAAAT
TTTCAAATTGAAGGTACTAGCATGGAACCAACCATGCAAACCAAGCAATATGTTTTGGTTAACAAAGCGATCTATGCTCA
TCTCGATTTGAATGCCCCACTGCGTTTGTGGCCTGGTCAAGCTGAGTTGCCCAAAAAATTCCTCTATTTGCTGCACCCAC
CTGAACGCGGTGATATTATTGTGTTTCTGGCTCCACCAGCGGCCCACGATTTGCCCGATAAAGATTATATCAAGCGGGTG
ATTGGGGTTGGTGGCGATACGATCAAAATTCGCGAGGGCAAGGTTTGGGTCAACGAGCAGCAATTAACCGAGGATTATAT
TGGCGAGGTTGATACGCTTTGTGATACCCATTGCGAGTTGGTTGTGCCCGAGGGGCATGTATTTGTGATGGGCGATAATC
GGCCATTTAGCAGCGATTCACGCCGTTGGGGGCCATTGCCGCTCGAATATGTGATTGGCAAGGCATGGTTTACCTATTGG
CCCAAAGAGCGCTGGGCGAGTTACTGA

Upstream 100 bases:

>100_bases
TGCCCTTAGATAATGTGATTGGCAAGGCTTGGCTTTCGTATTGGCCTAAAGAAGATTGGGGTGTTGTGCAAACGCCCAGT
TATGCAGCACCAACGGGCCA

Downstream 100 bases:

>100_bases
GTTCCCTCACCCCCAACCCCTCGCCCACTGCGGCGGGCGAGGGGCATTTGATTTGGTGGTTCCCCCTCGCGTGCGGGTGA
TGGGCGAGGGCTAGCTTACA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I-1; Leader peptidase I-1 [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNDFEQSEVKTTRLALDQTQPLPVAAPSAEEIAWLEQSQAPLPTPPTPTPALQRPRLRRSWHMLASLILSFLILRSLIQN
FQIEGTSMEPTMQTKQYVLVNKAIYAHLDLNAPLRLWPGQAELPKKFLYLLHPPERGDIIVFLAPPAAHDLPDKDYIKRV
IGVGGDTIKIREGKVWVNEQQLTEDYIGEVDTLCDTHCELVVPEGHVFVMGDNRPFSSDSRRWGPLPLEYVIGKAWFTYW
PKERWASY

Sequences:

>Translated_248_residues
MNDFEQSEVKTTRLALDQTQPLPVAAPSAEEIAWLEQSQAPLPTPPTPTPALQRPRLRRSWHMLASLILSFLILRSLIQN
FQIEGTSMEPTMQTKQYVLVNKAIYAHLDLNAPLRLWPGQAELPKKFLYLLHPPERGDIIVFLAPPAAHDLPDKDYIKRV
IGVGGDTIKIREGKVWVNEQQLTEDYIGEVDTLCDTHCELVVPEGHVFVMGDNRPFSSDSRRWGPLPLEYVIGKAWFTYW
PKERWASY
>Mature_248_residues
MNDFEQSEVKTTRLALDQTQPLPVAAPSAEEIAWLEQSQAPLPTPPTPTPALQRPRLRRSWHMLASLILSFLILRSLIQN
FQIEGTSMEPTMQTKQYVLVNKAIYAHLDLNAPLRLWPGQAELPKKFLYLLHPPERGDIIVFLAPPAAHDLPDKDYIKRV
IGVGGDTIKIREGKVWVNEQQLTEDYIGEVDTLCDTHCELVVPEGHVFVMGDNRPFSSDSRRWGPLPLEYVIGKAWFTYW
PKERWASY

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28351; Mature: 28351

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFEQSEVKTTRLALDQTQPLPVAAPSAEEIAWLEQSQAPLPTPPTPTPALQRPRLRRS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
WHMLASLILSFLILRSLIQNFQIEGTSMEPTMQTKQYVLVNKAIYAHLDLNAPLRLWPGQ
HHHHHHHHHHHHHHHHHHHHCEECCCCCCCCHHHHEEEEEEEEEEEEEECCCCEEECCCC
AELPKKFLYLLHPPERGDIIVFLAPPAAHDLPDKDYIKRVIGVGGDTIKIREGKVWVNEQ
CCCCHHEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCEEEECHH
QLTEDYIGEVDTLCDTHCELVVPEGHVFVMGDNRPFSSDSRRWGPLPLEYVIGKAWFTYW
HHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PKERWASY
CHHHHCCC
>Mature Secondary Structure
MNDFEQSEVKTTRLALDQTQPLPVAAPSAEEIAWLEQSQAPLPTPPTPTPALQRPRLRRS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
WHMLASLILSFLILRSLIQNFQIEGTSMEPTMQTKQYVLVNKAIYAHLDLNAPLRLWPGQ
HHHHHHHHHHHHHHHHHHHHCEECCCCCCCCHHHHEEEEEEEEEEEEEECCCCEEECCCC
AELPKKFLYLLHPPERGDIIVFLAPPAAHDLPDKDYIKRVIGVGGDTIKIREGKVWVNEQ
CCCCHHEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCEEEECHH
QLTEDYIGEVDTLCDTHCELVVPEGHVFVMGDNRPFSSDSRRWGPLPLEYVIGKAWFTYW
HHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PKERWASY
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]