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The map label for this gene is aldH [H]

Identifier: 159899023

GI number: 159899023

Start: 3198184

End: 3199755

Strand: Direct

Name: aldH [H]

Synonym: Haur_2504

Alternate gene names: 159899023

Gene position: 3198184-3199755 (Clockwise)

Preceding gene: 159899022

Following gene: 159899024

Centisome position: 50.39

GC content: 54.2

Gene sequence:

>1572_bases
ATGAAACCAATTTTAATCAACGGCGAATGGCAAATTGGCGATTACGTTGGTAGTTTTCATGCGACCAACCCAACCACAAC
CCAAGCATTCACCACCGAATATCCGATTTCGGGACGCGGCGATTTAGAATTAGCCTTGAGCGCTGGGGTTGCCGCCTCGC
GTGAGCTAGCCCAAAGTAGCCCTGAGCAACGCGCTAAATTTCTCGAAGGCTATGCCGATTTGATCGAGGCCAAGCGCCAA
GAACTGAGTGCAATCGCCCATAGCGAAACTGGCCTACCGATCGAGCCACGCTTGAATAGCGTTGAACTACCACGCACGGT
TAATCAATTGCGCCAAGCGGCTCAAGCAGTGCGCAACCACACCTGGGAGCTGGCAACAATCGACAGCAAAGCCAATATTC
GCTCGCTCTATGGCAGTTTGGCCGCACCAGTCGCCATTTTTGGGCCGAATAACTTCCCATTTGCCTATAATGCGATTGCT
GGCAGCGATTTTGCCTCGGCGATTGCTGCGGGAAATGCTGTAATCGCCAAAGGACACCCAAGCCACCCCGCCACCACCGA
GTTACTGGCTGAATTGGCGCATCAAGCAGTCTTGGCGGCTGGTTTGCCTGCGGCAAGTGTGCAATTGCTGTATGGTTTGC
CCGATGAATTGGGCTTGGCATTGGTCAGTCATCCTTTAATTGGGGCAATTGGCTTTACTGGTTCGCGCCGAGCAGGATTG
ACGCTCAAGGCTGCCGCCGATCAAGCAGGCAAGGCAATTTACCTTGAAATGTCGAGCATCAACCCGGTTGTGATGTTGGC
TGGAGCGGTGACCGAGCGGGCCGAAGCGCTTGCCGCCGAATTTGCTGGCTCGTGCACTTTGGGCGCTGGCCAATTTTGCA
CCAACCCTGGCTTATTAATTTTGGAGCATTCAGCGGCTAGTGCCGATTTTATTGAAGCAACCAAAGCCCACTTTAACCAA
CACCCTAGCCTGACCCTGCTCAACCATGGCGTTCTGGCTGGGCTTGAACAGGGCATTGAGCATTTGCAAGACGCTGGGGC
ACAGGTCTTGGTTGGTGGGCATGTGTTGGATGATGGGTATCGCTATGCCAATAGTTTGCTCTACGTTGCGGGCAATAGCT
TTCTGGCCAATCCCCAAGCGCTCAGCCATGAAGTCTTTGGGCCAGTCAGCTTGATTGTTGAATGTGCCGACCAAGCCGAA
GTATTGCGAGTGCTCGACTGCCTTGAGGGCAATTTGACGGGCAGCATCTACAGCAGCAGCAACGGGGCAGATGAAACCTT
TTATCAAATTGTTGCCGAGCGCTTACGCTCCAAAGTTGGGCGTTTGCTCAACGATAAAATGCCCACAGGTGTGGCCGTCA
GCTCAGCCATGAATCATGGCGGGCCGTATCCCGCGACAGGCCATGCAGGCTGGACGGCAGTGGGCTTTCCCGCAACGATT
CGGCGTTTTGCGGCGCTCCACTGCTACGACAACGTGCGCGAATCACGCTTGCCAAGCATTCTGCAAAACGCCAATCCGCA
AGCGATTTGGCGCTTGGTTGATGGCCAGTGGAGCAATGCTGGCATTGATTAG

Upstream 100 bases:

>100_bases
AAACTGTGCGAGCACCACGGCTTGAGTTAGTTGGAGCCGAGCGCGAAGCTGCCGTCAGCGTGATTGAACAAGCCTTGGCG
CGGCGGCAGGAGTTATGGCC

Downstream 100 bases:

>100_bases
CCTAGTTACTTAGCAAATTACACCACTTAAAGCAACGAAGGCTTAGCATTTAATCGTATTGCCACTCTTCCGTCCTGTTG
GAGGAGGTTTTTAAGGATCG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MKPILINGEWQIGDYVGSFHATNPTTTQAFTTEYPISGRGDLELALSAGVAASRELAQSSPEQRAKFLEGYADLIEAKRQ
ELSAIAHSETGLPIEPRLNSVELPRTVNQLRQAAQAVRNHTWELATIDSKANIRSLYGSLAAPVAIFGPNNFPFAYNAIA
GSDFASAIAAGNAVIAKGHPSHPATTELLAELAHQAVLAAGLPAASVQLLYGLPDELGLALVSHPLIGAIGFTGSRRAGL
TLKAAADQAGKAIYLEMSSINPVVMLAGAVTERAEALAAEFAGSCTLGAGQFCTNPGLLILEHSAASADFIEATKAHFNQ
HPSLTLLNHGVLAGLEQGIEHLQDAGAQVLVGGHVLDDGYRYANSLLYVAGNSFLANPQALSHEVFGPVSLIVECADQAE
VLRVLDCLEGNLTGSIYSSSNGADETFYQIVAERLRSKVGRLLNDKMPTGVAVSSAMNHGGPYPATGHAGWTAVGFPATI
RRFAALHCYDNVRESRLPSILQNANPQAIWRLVDGQWSNAGID

Sequences:

>Translated_523_residues
MKPILINGEWQIGDYVGSFHATNPTTTQAFTTEYPISGRGDLELALSAGVAASRELAQSSPEQRAKFLEGYADLIEAKRQ
ELSAIAHSETGLPIEPRLNSVELPRTVNQLRQAAQAVRNHTWELATIDSKANIRSLYGSLAAPVAIFGPNNFPFAYNAIA
GSDFASAIAAGNAVIAKGHPSHPATTELLAELAHQAVLAAGLPAASVQLLYGLPDELGLALVSHPLIGAIGFTGSRRAGL
TLKAAADQAGKAIYLEMSSINPVVMLAGAVTERAEALAAEFAGSCTLGAGQFCTNPGLLILEHSAASADFIEATKAHFNQ
HPSLTLLNHGVLAGLEQGIEHLQDAGAQVLVGGHVLDDGYRYANSLLYVAGNSFLANPQALSHEVFGPVSLIVECADQAE
VLRVLDCLEGNLTGSIYSSSNGADETFYQIVAERLRSKVGRLLNDKMPTGVAVSSAMNHGGPYPATGHAGWTAVGFPATI
RRFAALHCYDNVRESRLPSILQNANPQAIWRLVDGQWSNAGID
>Mature_523_residues
MKPILINGEWQIGDYVGSFHATNPTTTQAFTTEYPISGRGDLELALSAGVAASRELAQSSPEQRAKFLEGYADLIEAKRQ
ELSAIAHSETGLPIEPRLNSVELPRTVNQLRQAAQAVRNHTWELATIDSKANIRSLYGSLAAPVAIFGPNNFPFAYNAIA
GSDFASAIAAGNAVIAKGHPSHPATTELLAELAHQAVLAAGLPAASVQLLYGLPDELGLALVSHPLIGAIGFTGSRRAGL
TLKAAADQAGKAIYLEMSSINPVVMLAGAVTERAEALAAEFAGSCTLGAGQFCTNPGLLILEHSAASADFIEATKAHFNQ
HPSLTLLNHGVLAGLEQGIEHLQDAGAQVLVGGHVLDDGYRYANSLLYVAGNSFLANPQALSHEVFGPVSLIVECADQAE
VLRVLDCLEGNLTGSIYSSSNGADETFYQIVAERLRSKVGRLLNDKMPTGVAVSSAMNHGGPYPATGHAGWTAVGFPATI
RRFAALHCYDNVRESRLPSILQNANPQAIWRLVDGQWSNAGID

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=450, Percent_Identity=26.2222222222222, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI153266822, Length=444, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI25952152, Length=269, Percent_Identity=27.8810408921933, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI25777730, Length=437, Percent_Identity=24.9427917620137, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI21614513, Length=353, Percent_Identity=25.7790368271955, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI4507229, Length=359, Percent_Identity=24.7910863509749, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI25777732, Length=423, Percent_Identity=25.0591016548463, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI21361176, Length=426, Percent_Identity=24.1784037558685, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787558, Length=427, Percent_Identity=29.2740046838407, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082295, Length=434, Percent_Identity=24.4239631336406, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081896, Length=403, Percent_Identity=27.5434243176179, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787715, Length=386, Percent_Identity=27.2020725388601, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787684, Length=431, Percent_Identity=24.1299303944316, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789015, Length=428, Percent_Identity=24.5327102803738, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788042, Length=483, Percent_Identity=25.6728778467909, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786504, Length=433, Percent_Identity=24.9422632794457, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081926, Length=431, Percent_Identity=26.9141531322506, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787250, Length=432, Percent_Identity=25.2314814814815, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI133930964, Length=433, Percent_Identity=25.635103926097, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562198, Length=419, Percent_Identity=24.8210023866348, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551164, Length=423, Percent_Identity=23.1678486997636, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25144435, Length=425, Percent_Identity=25.4117647058824, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995606, Length=422, Percent_Identity=26.5402843601896, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71995613, Length=422, Percent_Identity=26.5402843601896, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32564736, Length=356, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=434, Percent_Identity=24.8847926267281, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324950, Length=437, Percent_Identity=23.3409610983982, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323822, Length=436, Percent_Identity=23.394495412844, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323821, Length=319, Percent_Identity=26.6457680250784, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325196, Length=444, Percent_Identity=22.972972972973, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362580, Length=453, Percent_Identity=25.3863134657837, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62472918, Length=453, Percent_Identity=25.3863134657837, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62472926, Length=453, Percent_Identity=25.3863134657837, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62472936, Length=453, Percent_Identity=25.3863134657837, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356737, Length=453, Percent_Identity=25.3863134657837, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24585660, Length=500, Percent_Identity=22.4, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129399, Length=434, Percent_Identity=23.2718894009217, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55122; Mature: 55122

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPILINGEWQIGDYVGSFHATNPTTTQAFTTEYPISGRGDLELALSAGVAASRELAQSS
CCCEEECCCEEECCHHCCEECCCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHCC
PEQRAKFLEGYADLIEAKRQELSAIAHSETGLPIEPRLNSVELPRTVNQLRQAAQAVRNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
TWELATIDSKANIRSLYGSLAAPVAIFGPNNFPFAYNAIAGSDFASAIAAGNAVIAKGHP
CEEEEEECCCHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCHHHHHHHCCCEEEECCCC
SHPATTELLAELAHQAVLAAGLPAASVQLLYGLPDELGLALVSHPLIGAIGFTGSRRAGL
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCHHHHHHHHHCCHHHHCCCCCCCCCCE
TLKAAADQAGKAIYLEMSSINPVVMLAGAVTERAEALAAEFAGSCTLGAGQFCTNPGLLI
EEEECCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LEHSAASADFIEATKAHFNQHPSLTLLNHGVLAGLEQGIEHLQDAGAQVLVGGHVLDDGY
EECCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCEEECCHH
RYANSLLYVAGNSFLANPQALSHEVFGPVSLIVECADQAEVLRVLDCLEGNLTGSIYSSS
HHHCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
NGADETFYQIVAERLRSKVGRLLNDKMPTGVAVSSAMNHGGPYPATGHAGWTAVGFPATI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCHHHH
RRFAALHCYDNVRESRLPSILQNANPQAIWRLVDGQWSNAGID
HHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MKPILINGEWQIGDYVGSFHATNPTTTQAFTTEYPISGRGDLELALSAGVAASRELAQSS
CCCEEECCCEEECCHHCCEECCCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHCC
PEQRAKFLEGYADLIEAKRQELSAIAHSETGLPIEPRLNSVELPRTVNQLRQAAQAVRNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
TWELATIDSKANIRSLYGSLAAPVAIFGPNNFPFAYNAIAGSDFASAIAAGNAVIAKGHP
CEEEEEECCCHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCHHHHHHHCCCEEEECCCC
SHPATTELLAELAHQAVLAAGLPAASVQLLYGLPDELGLALVSHPLIGAIGFTGSRRAGL
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCHHHHHHHHHCCHHHHCCCCCCCCCCE
TLKAAADQAGKAIYLEMSSINPVVMLAGAVTERAEALAAEFAGSCTLGAGQFCTNPGLLI
EEEECCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LEHSAASADFIEATKAHFNQHPSLTLLNHGVLAGLEQGIEHLQDAGAQVLVGGHVLDDGY
EECCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCEEECCHH
RYANSLLYVAGNSFLANPQALSHEVFGPVSLIVECADQAEVLRVLDCLEGNLTGSIYSSS
HHHCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
NGADETFYQIVAERLRSKVGRLLNDKMPTGVAVSSAMNHGGPYPATGHAGWTAVGFPATI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCHHHH
RRFAALHCYDNVRESRLPSILQNANPQAIWRLVDGQWSNAGID
HHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]