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The map label for this gene is dapA [H]

Identifier: 159899022

GI number: 159899022

Start: 3197273

End: 3198187

Strand: Direct

Name: dapA [H]

Synonym: Haur_2503

Alternate gene names: 159899022

Gene position: 3197273-3198187 (Clockwise)

Preceding gene: 159899021

Following gene: 159899023

Centisome position: 50.38

GC content: 55.3

Gene sequence:

>915_bases
ATGAGCATGTGGCATGGAGTTATTCCAGCAATCACCACCCGTTTTAATCACGATGGTAGCGTTGATCATGGATTTTTGGC
CGAGCACTGTGCTTGGATGTTGGATGCTGGCTGTGTTGGGATCGTGCCGCTTGGCTCTTTGGGCGAGGGTGCAACGCTTA
GCGCCGCCGAAAAACAGGCAATTTTACAAACCTGCGTCAAAGTGGCTGGCTCGAACCCAGTAATTCCAGGCATCGCGGCA
CTTTCAACTGCCGAAGCCTGCCAGCTAGCCCAAATCGCCGCTGCCGAAGGCTGCTCAGGCCTGATGGTGCTGCCACCTTA
TCTCTACTCGACCGATTGGCGCGAAATGCAAGCTCATATGAGCGCTGTGATCAGCGCCACCGAGTTGCCAGTGATGATCT
ACAACAATCCGGTGGCCTATCGCACCGATTTTGTGCCCAGCCAAATTGCCGAATTAGCACAACGCCATGCCAATGTGCAA
GCGGTCAAAGAATCGAGCACCGACGTGCGACGGGTGACGGCGATTCGGGCCGAACTTGGCCAACGCCTCGAAATTCTGGT
TGGGGTTGATGATGCAATTGTTGAGGGCATCGCGGCTGGGGCGGTTGGCTGGATCGCAGGCTTGGTCAATGCTTTTCCGC
ACGAATCGGTTGAGCTATTTCAACTAGCCCAAGCCGTTGCCGCAGGACATGGTGATCGCGCCCGACTCGACGCGATTTAC
ACTTGGTTCTTGCCATTGTTGCGGCTTGATACTGTGCCAAAATTTGTTCAATTGATTAAACTCACCCAAGCGATGGTCGG
CATGGGCAGCGAAACTGTGCGAGCACCACGGCTTGAGTTAGTTGGAGCCGAGCGCGAAGCTGCCGTCAGCGTGATTGAAC
AAGCCTTGGCGCGGCGGCAGGAGTTATGGCCATGA

Upstream 100 bases:

>100_bases
TGTGTGGCGGGGCAACGCAGTATTTATTTGGTTGGAGTCAAGATAGCGTGCGCTTTCCAATTCATTCGGTCAGCGTCGCC
GATTTAGTTATGGAGTCAGT

Downstream 100 bases:

>100_bases
AACCAATTTTAATCAACGGCGAATGGCAAATTGGCGATTACGTTGGTAGTTTTCATGCGACCAACCCAACCACAACCCAA
GCATTCACCACCGAATATCC

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSMWHGVIPAITTRFNHDGSVDHGFLAEHCAWMLDAGCVGIVPLGSLGEGATLSAAEKQAILQTCVKVAGSNPVIPGIAA
LSTAEACQLAQIAAAEGCSGLMVLPPYLYSTDWREMQAHMSAVISATELPVMIYNNPVAYRTDFVPSQIAELAQRHANVQ
AVKESSTDVRRVTAIRAELGQRLEILVGVDDAIVEGIAAGAVGWIAGLVNAFPHESVELFQLAQAVAAGHGDRARLDAIY
TWFLPLLRLDTVPKFVQLIKLTQAMVGMGSETVRAPRLELVGAEREAAVSVIEQALARRQELWP

Sequences:

>Translated_304_residues
MSMWHGVIPAITTRFNHDGSVDHGFLAEHCAWMLDAGCVGIVPLGSLGEGATLSAAEKQAILQTCVKVAGSNPVIPGIAA
LSTAEACQLAQIAAAEGCSGLMVLPPYLYSTDWREMQAHMSAVISATELPVMIYNNPVAYRTDFVPSQIAELAQRHANVQ
AVKESSTDVRRVTAIRAELGQRLEILVGVDDAIVEGIAAGAVGWIAGLVNAFPHESVELFQLAQAVAAGHGDRARLDAIY
TWFLPLLRLDTVPKFVQLIKLTQAMVGMGSETVRAPRLELVGAEREAAVSVIEQALARRQELWP
>Mature_303_residues
SMWHGVIPAITTRFNHDGSVDHGFLAEHCAWMLDAGCVGIVPLGSLGEGATLSAAEKQAILQTCVKVAGSNPVIPGIAAL
STAEACQLAQIAAAEGCSGLMVLPPYLYSTDWREMQAHMSAVISATELPVMIYNNPVAYRTDFVPSQIAELAQRHANVQA
VKESSTDVRRVTAIRAELGQRLEILVGVDDAIVEGIAAGAVGWIAGLVNAFPHESVELFQLAQAVAAGHGDRARLDAIYT
WFLPLLRLDTVPKFVQLIKLTQAMVGMGSETVRAPRLELVGAEREAAVSVIEQALARRQELWP

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082415, Length=302, Percent_Identity=27.4834437086093, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788823, Length=295, Percent_Identity=26.7796610169492, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786463, Length=293, Percent_Identity=26.962457337884, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789620, Length=208, Percent_Identity=29.8076923076923, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32526; Mature: 32395

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMWHGVIPAITTRFNHDGSVDHGFLAEHCAWMLDAGCVGIVPLGSLGEGATLSAAEKQA
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHH
ILQTCVKVAGSNPVIPGIAALSTAEACQLAQIAAAEGCSGLMVLPPYLYSTDWREMQAHM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCHHHHHHHH
SAVISATELPVMIYNNPVAYRTDFVPSQIAELAQRHANVQAVKESSTDVRRVTAIRAELG
HHHHHHHHCCEEEECCCCCEECCCCHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHC
QRLEILVGVDDAIVEGIAAGAVGWIAGLVNAFPHESVELFQLAQAVAAGHGDRARLDAIY
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
TWFLPLLRLDTVPKFVQLIKLTQAMVGMGSETVRAPRLELVGAEREAAVSVIEQALARRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHEECCCHHHHHHHHHHHHHHHH
ELWP
HCCC
>Mature Secondary Structure 
SMWHGVIPAITTRFNHDGSVDHGFLAEHCAWMLDAGCVGIVPLGSLGEGATLSAAEKQA
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHH
ILQTCVKVAGSNPVIPGIAALSTAEACQLAQIAAAEGCSGLMVLPPYLYSTDWREMQAHM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCHHHHHHHH
SAVISATELPVMIYNNPVAYRTDFVPSQIAELAQRHANVQAVKESSTDVRRVTAIRAELG
HHHHHHHHCCEEEECCCCCEECCCCHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHC
QRLEILVGVDDAIVEGIAAGAVGWIAGLVNAFPHESVELFQLAQAVAAGHGDRARLDAIY
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
TWFLPLLRLDTVPKFVQLIKLTQAMVGMGSETVRAPRLELVGAEREAAVSVIEQALARRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHEECCCHHHHHHHHHHHHHHHH
ELWP
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]