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The map label for this gene is dppB [H]

Identifier: 159898917

GI number: 159898917

Start: 3052607

End: 3053584

Strand: Reverse

Name: dppB [H]

Synonym: Haur_2396

Alternate gene names: 159898917

Gene position: 3053584-3052607 (Counterclockwise)

Preceding gene: 159898918

Following gene: 159898916

Centisome position: 48.11

GC content: 50.31

Gene sequence:

>978_bases
ATGCGTTTCTTGTTGCGACGGCTGGGCTTTTACGCGGTCGCGGCTTGGGTCTCGCTTACCGTCAATTTCTACCTACCCCG
GCTTATGCCTGGTGACCCAGCCTCGGCTATCTTCGCCCGTTTTCAAGGCCGCCTACGCCCTGAAGAAATCGATTCGCTGC
GCAAAGCTTATGGCCTAAGCGATGCCCCTTTGCTTGAACAATATTTCAACTACTTGAGAAGTTTGAGTCGCGGAGAGTTT
GGCATCTCGATCAATTTCTTTCCGGCCCAAGTTACCGATGTGATTTCAACTGGATTTATGTGGACTATCTTGTTGGCTGG
TTTAGCCACCGTGATTAGCTTTTTCTTGGGCAATGTCTTGGGGATTATCGGCGCTTGGCGGCGCAATGGCATCCTCGATT
CGGTCGCTCCACCTTTACTAACCTTCATCGGCGCATTTCCCTACTTCTTCTTAGCCATGATTGCGCTGTATTTCCTTGCA
TTTCAAGCAGGCTGGTTCCCGTTACGACACGCCTATAGCGATGCGCTATCGGTTGATTGGGGCAGCCTCACCTTTATAAA
GAGTGTTATCTCGCACATGATTTTGCCAGCAAGCTGTATTGTGCTGGCCTCGATTGGCGGTTGGATGCTCGGCATGCGCA
ATACCATGGTTGGGATTCTCTCCGAGGATTACATCACCATGGCGCAGGCTAAGGGTTTATCGCAACAACGAATTATGTTT
AGCTATGCTGCCCGCAATGCCTTATTGCCAAATGTTACCTCGTTTGGGATGGCACTCGGCTTTGTGCTCAGCGGCTCCTT
GCTCACCGAAATTATCTTTGCCTATCCAGGCTTGGGCTATTTGCTGTTGCAAGCAGTTCGCAACTTGGATTACCCATTGA
TGCAGGGCTTGTTTTTGATGATTACGTTTGCGGTGCTTGGGGCCAATCTGTTGGTTGACATATTGTATGTGTGGCTTGAT
CCACGCACTCGACGCTAG

Upstream 100 bases:

>100_bases
CATCAAACCAAAATAAGCTGTGTCTGGTTTGGTCGTGTGCTGGAGCCACTAGGCTCCAGCACCAACCCGACCCAGGCGCG
AAACCCTGAAAGGAAGAACC

Downstream 100 bases:

>100_bases
GAGTTGTGCCATGCAAGCATCACCGGAGAAAACCTTGGCTTCAAAGGCTGCCGAAACTTCCAAAACAAGCCGTCCATGGT
TGGCACACTGGCCGTTGCTA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRFLLRRLGFYAVAAWVSLTVNFYLPRLMPGDPASAIFARFQGRLRPEEIDSLRKAYGLSDAPLLEQYFNYLRSLSRGEF
GISINFFPAQVTDVISTGFMWTILLAGLATVISFFLGNVLGIIGAWRRNGILDSVAPPLLTFIGAFPYFFLAMIALYFLA
FQAGWFPLRHAYSDALSVDWGSLTFIKSVISHMILPASCIVLASIGGWMLGMRNTMVGILSEDYITMAQAKGLSQQRIMF
SYAARNALLPNVTSFGMALGFVLSGSLLTEIIFAYPGLGYLLLQAVRNLDYPLMQGLFLMITFAVLGANLLVDILYVWLD
PRTRR

Sequences:

>Translated_325_residues
MRFLLRRLGFYAVAAWVSLTVNFYLPRLMPGDPASAIFARFQGRLRPEEIDSLRKAYGLSDAPLLEQYFNYLRSLSRGEF
GISINFFPAQVTDVISTGFMWTILLAGLATVISFFLGNVLGIIGAWRRNGILDSVAPPLLTFIGAFPYFFLAMIALYFLA
FQAGWFPLRHAYSDALSVDWGSLTFIKSVISHMILPASCIVLASIGGWMLGMRNTMVGILSEDYITMAQAKGLSQQRIMF
SYAARNALLPNVTSFGMALGFVLSGSLLTEIIFAYPGLGYLLLQAVRNLDYPLMQGLFLMITFAVLGANLLVDILYVWLD
PRTRR
>Mature_325_residues
MRFLLRRLGFYAVAAWVSLTVNFYLPRLMPGDPASAIFARFQGRLRPEEIDSLRKAYGLSDAPLLEQYFNYLRSLSRGEF
GISINFFPAQVTDVISTGFMWTILLAGLATVISFFLGNVLGIIGAWRRNGILDSVAPPLLTFIGAFPYFFLAMIALYFLA
FQAGWFPLRHAYSDALSVDWGSLTFIKSVISHMILPASCIVLASIGGWMLGMRNTMVGILSEDYITMAQAKGLSQQRIMF
SYAARNALLPNVTSFGMALGFVLSGSLLTEIIFAYPGLGYLLLQAVRNLDYPLMQGLFLMITFAVLGANLLVDILYVWLD
PRTRR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=31.9648093841642, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=32.8125, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787497, Length=324, Percent_Identity=29.6296296296296, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=33.4328358208955, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789888, Length=328, Percent_Identity=31.0975609756098, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=27.1468144044321, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787550, Length=286, Percent_Identity=26.5734265734266, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36219; Mature: 36219

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLLRRLGFYAVAAWVSLTVNFYLPRLMPGDPASAIFARFQGRLRPEEIDSLRKAYGLS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
DAPLLEQYFNYLRSLSRGEFGISINFFPAQVTDVISTGFMWTILLAGLATVISFFLGNVL
CCHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIIGAWRRNGILDSVAPPLLTFIGAFPYFFLAMIALYFLAFQAGWFPLRHAYSDALSVDW
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GSLTFIKSVISHMILPASCIVLASIGGWMLGMRNTMVGILSEDYITMAQAKGLSQQRIMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SYAARNALLPNVTSFGMALGFVLSGSLLTEIIFAYPGLGYLLLQAVRNLDYPLMQGLFLM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
ITFAVLGANLLVDILYVWLDPRTRR
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRFLLRRLGFYAVAAWVSLTVNFYLPRLMPGDPASAIFARFQGRLRPEEIDSLRKAYGLS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
DAPLLEQYFNYLRSLSRGEFGISINFFPAQVTDVISTGFMWTILLAGLATVISFFLGNVL
CCHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIIGAWRRNGILDSVAPPLLTFIGAFPYFFLAMIALYFLAFQAGWFPLRHAYSDALSVDW
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GSLTFIKSVISHMILPASCIVLASIGGWMLGMRNTMVGILSEDYITMAQAKGLSQQRIMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SYAARNALLPNVTSFGMALGFVLSGSLLTEIIFAYPGLGYLLLQAVRNLDYPLMQGLFLM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
ITFAVLGANLLVDILYVWLDPRTRR
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]