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The map label for this gene is appC [H]

Identifier: 159898916

GI number: 159898916

Start: 3051592

End: 3052596

Strand: Reverse

Name: appC [H]

Synonym: Haur_2395

Alternate gene names: 159898916

Gene position: 3052596-3051592 (Counterclockwise)

Preceding gene: 159898917

Following gene: 159898915

Centisome position: 48.1

GC content: 53.73

Gene sequence:

>1005_bases
ATGCAAGCATCACCGGAGAAAACCTTGGCTTCAAAGGCTGCCGAAACTTCCAAAACAAGCCGTCCATGGTTGGCACACTG
GCCGTTGCTACGGGCATTCTTGCGTAATCGCAAGGCGATGCTCGGCGTAAGCATTATGTTCTTCTTTGTGATGGTGGCCC
TGCTGGCCCCATGGATTGCCCCAGGCAACCCCAAAAAGATGGAAAGCCGTGCCCACTTGGCCCCAGCTTGGATCGCTGAT
AAGCCTGCTCCAGGTGGCAAAACCTTCTTACTTGGCACAACTGGTCAAGGCCAAGATGTGTTTCGTCAGCTGGTTTGGGG
CTCACGTTTATCGCTCACGGTTGGCCTGAGTGTCGGCATTGCCTCAACGATTTTGGGCACAATTATCGGCTTGACCGCTG
GCTATCTGGGTGGTTGGGTTGATGATGTGCTCTCATTGTTGACCAATGTGATGCTGATTATTCCTGGTATGCCGTTGTTG
GTTATTCTTGCGGCCTTTCTCAAGCCAGGGCCGGTGACCGTTGTAATGGTGCTGACCATTACCGGGTGGGCTTGGCCAGC
CCGCGTTATGCGTTCGCAGGTGCTTTCGCTTAGGGCCAAAGATTTTATCGCGGCCTCGGTGGTGAGCGGCGAACGAACTC
CACGGATTTTGTTTAGCGAAGTCTTGCCAAATATGTCCTCGGTGTTTGTTGGGAGCATGGTTGGTTCGACGGTGTATGCA
ATTGGCGCTGATGTTGGTTTGGCCTTCCTTGGCTTGACCGATGTTGGCACAACCAGCTGGGGCACGATGCTCTACTGGGC
GCAAAATAATGCTGGCATCTTGACCGGAGCTTGGTGGACATTCGTCCCAGTCGGCATTTGTATTGCCTTGTGTGCCTTTG
CCTTAACCATGCTGAACTATGCCCTTGACGAAATTACCAACCCTCGCTTACGTGCCGAAAAGGAGACCACTCATGGCAAG
CGCTCCCGTGCCAACGTCCTTGTCACCCCAGTCATCCGCAAGTAG

Upstream 100 bases:

>100_bases
TTGTTTTTGATGATTACGTTTGCGGTGCTTGGGGCCAATCTGTTGGTTGACATATTGTATGTGTGGCTTGATCCACGCAC
TCGACGCTAGGAGTTGTGCC

Downstream 100 bases:

>100_bases
TGCGGCTGAGCCGTTGCTCGATGTTCAGAACCTATCGGTCGAATACCAGACGTTGCGCGGCCCAGTCCAAGCTGTTTCCA
ACGTTTCGTTTAGCATCGGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MQASPEKTLASKAAETSKTSRPWLAHWPLLRAFLRNRKAMLGVSIMFFFVMVALLAPWIAPGNPKKMESRAHLAPAWIAD
KPAPGGKTFLLGTTGQGQDVFRQLVWGSRLSLTVGLSVGIASTILGTIIGLTAGYLGGWVDDVLSLLTNVMLIIPGMPLL
VILAAFLKPGPVTVVMVLTITGWAWPARVMRSQVLSLRAKDFIAASVVSGERTPRILFSEVLPNMSSVFVGSMVGSTVYA
IGADVGLAFLGLTDVGTTSWGTMLYWAQNNAGILTGAWWTFVPVGICIALCAFALTMLNYALDEITNPRLRAEKETTHGK
RSRANVLVTPVIRK

Sequences:

>Translated_334_residues
MQASPEKTLASKAAETSKTSRPWLAHWPLLRAFLRNRKAMLGVSIMFFFVMVALLAPWIAPGNPKKMESRAHLAPAWIAD
KPAPGGKTFLLGTTGQGQDVFRQLVWGSRLSLTVGLSVGIASTILGTIIGLTAGYLGGWVDDVLSLLTNVMLIIPGMPLL
VILAAFLKPGPVTVVMVLTITGWAWPARVMRSQVLSLRAKDFIAASVVSGERTPRILFSEVLPNMSSVFVGSMVGSTVYA
IGADVGLAFLGLTDVGTTSWGTMLYWAQNNAGILTGAWWTFVPVGICIALCAFALTMLNYALDEITNPRLRAEKETTHGK
RSRANVLVTPVIRK
>Mature_334_residues
MQASPEKTLASKAAETSKTSRPWLAHWPLLRAFLRNRKAMLGVSIMFFFVMVALLAPWIAPGNPKKMESRAHLAPAWIAD
KPAPGGKTFLLGTTGQGQDVFRQLVWGSRLSLTVGLSVGIASTILGTIIGLTAGYLGGWVDDVLSLLTNVMLIIPGMPLL
VILAAFLKPGPVTVVMVLTITGWAWPARVMRSQVLSLRAKDFIAASVVSGERTPRILFSEVLPNMSSVFVGSMVGSTVYA
IGADVGLAFLGLTDVGTTSWGTMLYWAQNNAGILTGAWWTFVPVGICIALCAFALTMLNYALDEITNPRLRAEKETTHGK
RSRANVLVTPVIRK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=282, Percent_Identity=33.6879432624113, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787054, Length=301, Percent_Identity=26.2458471760797, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787498, Length=290, Percent_Identity=26.8965517241379, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789889, Length=232, Percent_Identity=28.8793103448276, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787760, Length=273, Percent_Identity=24.5421245421245, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788505, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787549, Length=239, Percent_Identity=27.1966527196653, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35950; Mature: 35950

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASPEKTLASKAAETSKTSRPWLAHWPLLRAFLRNRKAMLGVSIMFFFVMVALLAPWIA
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
PGNPKKMESRAHLAPAWIADKPAPGGKTFLLGTTGQGQDVFRQLVWGSRLSLTVGLSVGI
CCCCHHHHHHHCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEHHHHH
ASTILGTIIGLTAGYLGGWVDDVLSLLTNVMLIIPGMPLLVILAAFLKPGPVTVVMVLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEC
TGWAWPARVMRSQVLSLRAKDFIAASVVSGERTPRILFSEVLPNMSSVFVGSMVGSTVYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
IGADVGLAFLGLTDVGTTSWGTMLYWAQNNAGILTGAWWTFVPVGICIALCAFALTMLNY
HHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
ALDEITNPRLRAEKETTHGKRSRANVLVTPVIRK
HHHHHCCCCCCCCCHHCCCCCCCCCEEEECCCCC
>Mature Secondary Structure
MQASPEKTLASKAAETSKTSRPWLAHWPLLRAFLRNRKAMLGVSIMFFFVMVALLAPWIA
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
PGNPKKMESRAHLAPAWIADKPAPGGKTFLLGTTGQGQDVFRQLVWGSRLSLTVGLSVGI
CCCCHHHHHHHCCCCHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEHHHHH
ASTILGTIIGLTAGYLGGWVDDVLSLLTNVMLIIPGMPLLVILAAFLKPGPVTVVMVLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEC
TGWAWPARVMRSQVLSLRAKDFIAASVVSGERTPRILFSEVLPNMSSVFVGSMVGSTVYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
IGADVGLAFLGLTDVGTTSWGTMLYWAQNNAGILTGAWWTFVPVGICIALCAFALTMLNY
HHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
ALDEITNPRLRAEKETTHGKRSRANVLVTPVIRK
HHHHHCCCCCCCCCHHCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]