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The map label for this gene is bga [H]

Identifier: 159898913

GI number: 159898913

Start: 3047564

End: 3049582

Strand: Reverse

Name: bga [H]

Synonym: Haur_2392

Alternate gene names: 159898913

Gene position: 3049582-3047564 (Counterclockwise)

Preceding gene: 159898914

Following gene: 159898912

Centisome position: 48.05

GC content: 52.4

Gene sequence:

>2019_bases
ATGAGCGTGACGCTGACTGCCAACGGTCTTGCAGTCAATGGTCAGGAAGTGCCGGTTTATTCCGGCACTATTCACTATTG
GCGTTTAGAGCGCGACCGCTGGGACTATATTCTCGACCAAGCTAAGGCGCTTGGGTTTTCGATGATCGAAACCTACATTC
CTTGGGGCGTGCATGAAACCGCTCCCGGTCAATACGATTGGGGCCAAATCGATCCACGCAAAGATCTCGCGGCCTTTATG
CGTTTGTGCCATGAACGGGGAATCTGGCTCATTGCGCGGCCTGGGCCATTGATCAATGCTGAATTGACCGACTTTGGCTT
TCCCCAATGGATTTTGGACGATCCAGCGATGCAAGCTCGCACCGTGCTGGATACCATGCATATGAGCTTAGCAGCGGGTT
TGCATCCACCACATCAATTTCCCGTGCCATCGTATACCAGCCCTGAATATTTGGCCGCCGTGGGCGTTTGGTTCGACCAC
ATGTGCCAAGTGATTGTGCCGCAACTTGCGCCGCATGGGCCAATTGTCGCGGTGCAAAGCGATAATGAAACCTGCTATAT
GTTTCATGAGCAAGCTTATGCGACCGATTACAGCCCTTCGTCGTTGGCCTTGTATCAAGCAATGTTGGCTGAGCAATATG
GCGCAATCGAAGAATTGAATCAAGCCTATGCGACCAACTATGCCAATTTCAGCGAAGTGATTGCGCCGCGCGATGCCGAT
ATCGCCAGCCGCCCCGATTTAGTGGCTCACCTCGATTGGGTGCGCTACAAAGAAGTGCATGTTAATTGGATTGTCGCGAC
CATGGCCGATATGCTGCGTGAGCGTGGCGTGGTTGATGTGCCATTATTCCACGATGTAGCCTTCCAGTATCGCACGCCGC
TGGATATTAACGCCATGGAAGCCAACGGCCATGTCGATTGGGTTGGGATCAACTATTATCGCCAACCACAAGGCTTTGAT
GGCGCGATCACCTTAGTGCGCTATATGGCTGGTACCACGCGCCTGCCGTTTATCCCTGAATTTGGCAGCGGCTTGTGGAT
TCACCATGCGCTCACGCCACGGCCTGAAGAAGCAGAATTTGTAACTTTAGCGGCCTTGATGTATGGAATTAAAGCCTTCA
ATTTCTATATGTTGGTCGAGCGTGATCGTTGGTTGGCCTGCCCAATCACTCGTCATGGCGATTATCGACCGGAATATGCG
CAATTGTTTGAGCGCTTGATGGGCTTTTTGCAGCAGCAACAATGGTGGAACTTCCAGCGCAAACCTGAAGTTTTGGTGCT
GATGAGCTATGATCTTGGGCGCTATTGGGCCGCCACTTCAACCTTGCACTATGGCCATGTTGATTTACTCGGCCTGCCGC
CAGCATTAAATCGGGTCGAATTGGATTTGGGCTTTAGCACCGATCTCGAAGTTGAAAGCGACGATTTTCATCCGCAAAGT
TGGTATGGCTCGTTGCGGAGCACGCTCGATGCCAACCATATCGACTACGATTTGAGCGATAGCCATTTGCGCAGCTCACG
AATTGCTGACTATAAATTGGTGTTTGCCCAGAGCGTCGATTGGATGAGCCGCGCCGATCAACAGCGGTTGTTGCAGGCTG
CCGAAACTGGTGCAACCGTTTGGCTTGGCCCGACCTTGCCAACCCTTGACGAATACTTCCAGCCCTGCACAATCTTGGCT
GATCAATTGGCGGGCAAACGCCAAGTTGCCTTGGGCAGTGGCCATTTGGGCTTACTGAGCCAAGCCGAATTAGGCGCATT
TTGTGCCGAAGTTGCAGCGGGTTTGCCTGTACGGCCCCAAAACCCTCAATTGGCGGTTACCAGCCATCGTCACCAAGGCC
GCGAAATTCTGTTTGTAGCCAACCCAACCGCTGAAACGATTAACTCAAGCTTGGATTTTGCCCATCCTGTGCGCTTAACC
AGCTTGTGGGGAGCATTCGCTGGCGCTGATCTTCAACAACAGCAGCCGATTAGCCTAGCAGCCTACACGATTGCAATTGT
CGAGGTGCAGCATGATTGA

Upstream 100 bases:

>100_bases
AGGATGTTTGTCGTAAAGTAATGCCCGATGTGCAGACGATTGCGCCAAATCACTGGGTTCGTTGCCATTTGTATGGTGAG
GGCACTGGAGGAACTGCGGC

Downstream 100 bases:

>100_bases
TCGTTTTTGGCAGGTGTTGGATCTTGACCCAATCACATGGCGCAATATTGGGCGCTTTATCGAGGTTGGCAAATACATCC
AAGCTGCGCGGCCTGGCGAA

Product: beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSVTLTANGLAVNGQEVPVYSGTIHYWRLERDRWDYILDQAKALGFSMIETYIPWGVHETAPGQYDWGQIDPRKDLAAFM
RLCHERGIWLIARPGPLINAELTDFGFPQWILDDPAMQARTVLDTMHMSLAAGLHPPHQFPVPSYTSPEYLAAVGVWFDH
MCQVIVPQLAPHGPIVAVQSDNETCYMFHEQAYATDYSPSSLALYQAMLAEQYGAIEELNQAYATNYANFSEVIAPRDAD
IASRPDLVAHLDWVRYKEVHVNWIVATMADMLRERGVVDVPLFHDVAFQYRTPLDINAMEANGHVDWVGINYYRQPQGFD
GAITLVRYMAGTTRLPFIPEFGSGLWIHHALTPRPEEAEFVTLAALMYGIKAFNFYMLVERDRWLACPITRHGDYRPEYA
QLFERLMGFLQQQQWWNFQRKPEVLVLMSYDLGRYWAATSTLHYGHVDLLGLPPALNRVELDLGFSTDLEVESDDFHPQS
WYGSLRSTLDANHIDYDLSDSHLRSSRIADYKLVFAQSVDWMSRADQQRLLQAAETGATVWLGPTLPTLDEYFQPCTILA
DQLAGKRQVALGSGHLGLLSQAELGAFCAEVAAGLPVRPQNPQLAVTSHRHQGREILFVANPTAETINSSLDFAHPVRLT
SLWGAFAGADLQQQQPISLAAYTIAIVEVQHD

Sequences:

>Translated_672_residues
MSVTLTANGLAVNGQEVPVYSGTIHYWRLERDRWDYILDQAKALGFSMIETYIPWGVHETAPGQYDWGQIDPRKDLAAFM
RLCHERGIWLIARPGPLINAELTDFGFPQWILDDPAMQARTVLDTMHMSLAAGLHPPHQFPVPSYTSPEYLAAVGVWFDH
MCQVIVPQLAPHGPIVAVQSDNETCYMFHEQAYATDYSPSSLALYQAMLAEQYGAIEELNQAYATNYANFSEVIAPRDAD
IASRPDLVAHLDWVRYKEVHVNWIVATMADMLRERGVVDVPLFHDVAFQYRTPLDINAMEANGHVDWVGINYYRQPQGFD
GAITLVRYMAGTTRLPFIPEFGSGLWIHHALTPRPEEAEFVTLAALMYGIKAFNFYMLVERDRWLACPITRHGDYRPEYA
QLFERLMGFLQQQQWWNFQRKPEVLVLMSYDLGRYWAATSTLHYGHVDLLGLPPALNRVELDLGFSTDLEVESDDFHPQS
WYGSLRSTLDANHIDYDLSDSHLRSSRIADYKLVFAQSVDWMSRADQQRLLQAAETGATVWLGPTLPTLDEYFQPCTILA
DQLAGKRQVALGSGHLGLLSQAELGAFCAEVAAGLPVRPQNPQLAVTSHRHQGREILFVANPTAETINSSLDFAHPVRLT
SLWGAFAGADLQQQQPISLAAYTIAIVEVQHD
>Mature_671_residues
SVTLTANGLAVNGQEVPVYSGTIHYWRLERDRWDYILDQAKALGFSMIETYIPWGVHETAPGQYDWGQIDPRKDLAAFMR
LCHERGIWLIARPGPLINAELTDFGFPQWILDDPAMQARTVLDTMHMSLAAGLHPPHQFPVPSYTSPEYLAAVGVWFDHM
CQVIVPQLAPHGPIVAVQSDNETCYMFHEQAYATDYSPSSLALYQAMLAEQYGAIEELNQAYATNYANFSEVIAPRDADI
ASRPDLVAHLDWVRYKEVHVNWIVATMADMLRERGVVDVPLFHDVAFQYRTPLDINAMEANGHVDWVGINYYRQPQGFDG
AITLVRYMAGTTRLPFIPEFGSGLWIHHALTPRPEEAEFVTLAALMYGIKAFNFYMLVERDRWLACPITRHGDYRPEYAQ
LFERLMGFLQQQQWWNFQRKPEVLVLMSYDLGRYWAATSTLHYGHVDLLGLPPALNRVELDLGFSTDLEVESDDFHPQSW
YGSLRSTLDANHIDYDLSDSHLRSSRIADYKLVFAQSVDWMSRADQQRLLQAAETGATVWLGPTLPTLDEYFQPCTILAD
QLAGKRQVALGSGHLGLLSQAELGAFCAEVAAGLPVRPQNPQLAVTSHRHQGREILFVANPTAETINSSLDFAHPVRLTS
LWGAFAGADLQQQQPISLAAYTIAIVEVQHD

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI31543093, Length=176, Percent_Identity=34.6590909090909, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI164519026, Length=185, Percent_Identity=31.3513513513514, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI119372308, Length=176, Percent_Identity=34.6590909090909, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI119372312, Length=176, Percent_Identity=34.6590909090909, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI40255043, Length=206, Percent_Identity=28.6407766990291, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72000600, Length=180, Percent_Identity=31.1111111111111, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24582088, Length=183, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646169, Length=173, Percent_Identity=28.9017341040462, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 75827; Mature: 75695

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTLTANGLAVNGQEVPVYSGTIHYWRLERDRWDYILDQAKALGFSMIETYIPWGVHET
CEEEEEECCEEECCCCCEEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APGQYDWGQIDPRKDLAAFMRLCHERGIWLIARPGPLINAELTDFGFPQWILDDPAMQAR
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHH
TVLDTMHMSLAAGLHPPHQFPVPSYTSPEYLAAVGVWFDHMCQVIVPQLAPHGPIVAVQS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DNETCYMFHEQAYATDYSPSSLALYQAMLAEQYGAIEELNQAYATNYANFSEVIAPRDAD
CCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCC
IASRPDLVAHLDWVRYKEVHVNWIVATMADMLRERGVVDVPLFHDVAFQYRTPLDINAME
CCCCCCHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCCEECCHHHHHHHHCCCCCCCEEEE
ANGHVDWVGINYYRQPQGFDGAITLVRYMAGTTRLPFIPEFGSGLWIHHALTPRPEEAEF
CCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHH
VTLAALMYGIKAFNFYMLVERDRWLACPITRHGDYRPEYAQLFERLMGFLQQQQWWNFQR
HHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
KPEVLVLMSYDLGRYWAATSTLHYGHVDLLGLPPALNRVELDLGFSTDLEVESDDFHPQS
CCCEEEEEECCCCCCEECCCEEEECCEEEEECCCCCCEEEEEECCCCCCEECCCCCCCHH
WYGSLRSTLDANHIDYDLSDSHLRSSRIADYKLVFAQSVDWMSRADQQRLLQAAETGATV
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEE
WLGPTLPTLDEYFQPCTILADQLAGKRQVALGSGHLGLLSQAELGAFCAEVAAGLPVRPQ
EECCCCCCHHHHHCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCC
NPQLAVTSHRHQGREILFVANPTAETINSSLDFAHPVRLTSLWGAFAGADLQQQQPISLA
CCCEEEECCCCCCCEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEE
AYTIAIVEVQHD
EEEEEEEEEECC
>Mature Secondary Structure 
SVTLTANGLAVNGQEVPVYSGTIHYWRLERDRWDYILDQAKALGFSMIETYIPWGVHET
EEEEEECCEEECCCCCEEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APGQYDWGQIDPRKDLAAFMRLCHERGIWLIARPGPLINAELTDFGFPQWILDDPAMQAR
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHH
TVLDTMHMSLAAGLHPPHQFPVPSYTSPEYLAAVGVWFDHMCQVIVPQLAPHGPIVAVQS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
DNETCYMFHEQAYATDYSPSSLALYQAMLAEQYGAIEELNQAYATNYANFSEVIAPRDAD
CCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCC
IASRPDLVAHLDWVRYKEVHVNWIVATMADMLRERGVVDVPLFHDVAFQYRTPLDINAME
CCCCCCHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCCEECCHHHHHHHHCCCCCCCEEEE
ANGHVDWVGINYYRQPQGFDGAITLVRYMAGTTRLPFIPEFGSGLWIHHALTPRPEEAEF
CCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHH
VTLAALMYGIKAFNFYMLVERDRWLACPITRHGDYRPEYAQLFERLMGFLQQQQWWNFQR
HHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
KPEVLVLMSYDLGRYWAATSTLHYGHVDLLGLPPALNRVELDLGFSTDLEVESDDFHPQS
CCCEEEEEECCCCCCEECCCEEEECCEEEEECCCCCCEEEEEECCCCCCEECCCCCCCHH
WYGSLRSTLDANHIDYDLSDSHLRSSRIADYKLVFAQSVDWMSRADQQRLLQAAETGATV
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEE
WLGPTLPTLDEYFQPCTILADQLAGKRQVALGSGHLGLLSQAELGAFCAEVAAGLPVRPQ
EECCCCCCHHHHHCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCC
NPQLAVTSHRHQGREILFVANPTAETINSSLDFAHPVRLTSLWGAFAGADLQQQQPISLA
CCCEEEECCCCCCCEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEE
AYTIAIVEVQHD
EEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]