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The map label for this gene is asnC

Identifier: 159898884

GI number: 159898884

Start: 3010195

End: 3011538

Strand: Reverse

Name: asnC

Synonym: Haur_2363

Alternate gene names: 159898884

Gene position: 3011538-3010195 (Counterclockwise)

Preceding gene: 159898885

Following gene: 159898881

Centisome position: 47.45

GC content: 49.03

Gene sequence:

>1344_bases
ATGGCACTGCTGCCCTCGATGTATATCCGCGATAGCGCCGACCATGTTGGCGAAGCGGTCAAACTTGCTGGTTGGGTCTA
TCACAAAACCGAAAAAGGCAAGTTGGTTTTTATTCAATTACGCGATGGTACCGCCACGATTCAATGTGTGGTGTTTAAAA
AGAATGTCAGCGAAGAAGTTTTTGCGCGAGCCAAAGAATTAACTCAAGAATCTTCGTGCTATATCCATGGTACACTTCGC
GCCGACGAACGCTCGAGCTTGGGTTTTGAATTAGATGTTACTGATATCGAAATTGTGCATCTAACCCAAAATTACCCAAT
TACCCCCAAAGAGCATGGCACGCAATTTTTGATGGAGCATCGCCATCTGTGGGTGCGCTCTGCCAAACAACATGCCTTGT
TGCGCATTCGTGCTCAAGTGATTGCCGCAGCCCAAGAATATTTGAACAGCGAACATTTTGTGCGCTACGACTCGCCGATT
CTCACGGCAACCGCTGCTGAAGGTACGAGCGACTTGTTTGCCACCGAATATTTCGATTTGGGTAATGCCTATTTGGCCCA
AACTGGCCAGCTTTACGTTGAATCGGGCATGGCAACCTTTGGTCGGGTTTATTGTTTTGGCCCCACTTTTCGGGCTGAAA
AATCTAAAACTCGTCGCCACCTGACCGAATTTTGGATGATCGAGCCAGAATTTGCCTTCGCTGACCAAGACGATAATATG
GAATTGCAAGAAAATTTCGTTTCCTATATCGTCCAACGCGTGCTTGATCGCTGCGAAGAAGATCTCAAAATTTTAGAGCG
CGATACCTCGAAGCTCGAAAATATTGTGCCACCCTTCCCCCGTATCAGCTACGACGAGGCGATTGAAAAAATCAAGCAAG
GTGTGGCGGCAGGGGCAACTGTTGCTCCCGATAATGCACCATTAGCCGATTTGGAATGGGGCGACGATTTTGGCGCACCC
CATGAAACCTACTTGGCCAGCTTGTTTGATAAACCCTTATTTATCTACAACTATCCAACCAAGGTCAAAGCCTTTTATAT
GCAACCAGCCGAAGGCCGCCCTGAAGTGGTGCGCTGCGCCGATTTGATCGCTCCCGAAGGCTATGGCGAAATTATCGGTG
GCTCACAACGGATTCACGATGCTGAGTTGCTCGAAGCACGCATTCGTGAGCATGGCCTTGATGTCGCCGATTACCAATGG
TATTTGGATTTGCGGCGTTATGGCAGTGTGCCGCACTCAGGCTTTGGCATGGGGATCGAACGCTGTGTTGCTTGGCTGGC
AGGTACGCGCCACATCCGCGAGGCGATTCCTTTCCCACGCCAACTATATCGTATTTATCCATAA

Upstream 100 bases:

>100_bases
TTCTCAAGTAGTTGGTTGCGGCAGTACATGGTATTATTGCGAGAAATATGGCGGTGCCTTGGTGCATCGCCATTGTGTTG
TTTTGTTGGAAGGAGCATCT

Downstream 100 bases:

>100_bases
GGCTTGGGGATTGGTTGTTGGTTGTTGGGGATCGGAAATTTTAACGCAGAGGCGGCGAGGGGTCAGGATTCAGGGGCGAG
GGGTCAGGATTCAGGGGCGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MALLPSMYIRDSADHVGEAVKLAGWVYHKTEKGKLVFIQLRDGTATIQCVVFKKNVSEEVFARAKELTQESSCYIHGTLR
ADERSSLGFELDVTDIEIVHLTQNYPITPKEHGTQFLMEHRHLWVRSAKQHALLRIRAQVIAAAQEYLNSEHFVRYDSPI
LTATAAEGTSDLFATEYFDLGNAYLAQTGQLYVESGMATFGRVYCFGPTFRAEKSKTRRHLTEFWMIEPEFAFADQDDNM
ELQENFVSYIVQRVLDRCEEDLKILERDTSKLENIVPPFPRISYDEAIEKIKQGVAAGATVAPDNAPLADLEWGDDFGAP
HETYLASLFDKPLFIYNYPTKVKAFYMQPAEGRPEVVRCADLIAPEGYGEIIGGSQRIHDAELLEARIREHGLDVADYQW
YLDLRRYGSVPHSGFGMGIERCVAWLAGTRHIREAIPFPRQLYRIYP

Sequences:

>Translated_447_residues
MALLPSMYIRDSADHVGEAVKLAGWVYHKTEKGKLVFIQLRDGTATIQCVVFKKNVSEEVFARAKELTQESSCYIHGTLR
ADERSSLGFELDVTDIEIVHLTQNYPITPKEHGTQFLMEHRHLWVRSAKQHALLRIRAQVIAAAQEYLNSEHFVRYDSPI
LTATAAEGTSDLFATEYFDLGNAYLAQTGQLYVESGMATFGRVYCFGPTFRAEKSKTRRHLTEFWMIEPEFAFADQDDNM
ELQENFVSYIVQRVLDRCEEDLKILERDTSKLENIVPPFPRISYDEAIEKIKQGVAAGATVAPDNAPLADLEWGDDFGAP
HETYLASLFDKPLFIYNYPTKVKAFYMQPAEGRPEVVRCADLIAPEGYGEIIGGSQRIHDAELLEARIREHGLDVADYQW
YLDLRRYGSVPHSGFGMGIERCVAWLAGTRHIREAIPFPRQLYRIYP
>Mature_446_residues
ALLPSMYIRDSADHVGEAVKLAGWVYHKTEKGKLVFIQLRDGTATIQCVVFKKNVSEEVFARAKELTQESSCYIHGTLRA
DERSSLGFELDVTDIEIVHLTQNYPITPKEHGTQFLMEHRHLWVRSAKQHALLRIRAQVIAAAQEYLNSEHFVRYDSPIL
TATAAEGTSDLFATEYFDLGNAYLAQTGQLYVESGMATFGRVYCFGPTFRAEKSKTRRHLTEFWMIEPEFAFADQDDNME
LQENFVSYIVQRVLDRCEEDLKILERDTSKLENIVPPFPRISYDEAIEKIKQGVAAGATVAPDNAPLADLEWGDDFGAPH
ETYLASLFDKPLFIYNYPTKVKAFYMQPAEGRPEVVRCADLIAPEGYGEIIGGSQRIHDAELLEARIREHGLDVADYQWY
LDLRRYGSVPHSGFGMGIERCVAWLAGTRHIREAIPFPRQLYRIYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=462, Percent_Identity=34.1991341991342, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI4758762, Length=440, Percent_Identity=30.2272727272727, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI45439306, Length=484, Percent_Identity=27.6859504132231, Blast_Score=165, Evalue=9e-41,
Organism=Escherichia coli, GI1787161, Length=474, Percent_Identity=33.5443037974684, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790571, Length=450, Percent_Identity=25.1111111111111, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789256, Length=449, Percent_Identity=24.0534521158129, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788173, Length=246, Percent_Identity=26.4227642276423, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71984122, Length=447, Percent_Identity=34.2281879194631, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17551876, Length=468, Percent_Identity=27.7777777777778, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17556372, Length=426, Percent_Identity=30.2816901408451, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6321807, Length=449, Percent_Identity=32.5167037861915, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6319872, Length=464, Percent_Identity=29.7413793103448, Blast_Score=196, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=482, Percent_Identity=29.8755186721992, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI19921528, Length=436, Percent_Identity=33.4862385321101, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI19922416, Length=452, Percent_Identity=28.7610619469027, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI17136276, Length=458, Percent_Identity=27.5109170305677, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_HERA2 (A9AYM5)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545131.1
- ProteinModelPortal:   A9AYM5
- SMR:   A9AYM5
- GeneID:   5734244
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_2363
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   HAUR316274:HAUR_2363-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 50948; Mature: 50817

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLPSMYIRDSADHVGEAVKLAGWVYHKTEKGKLVFIQLRDGTATIQCVVFKKNVSEEV
CCCCCCHHHCCCHHHHHHHHHHHHHEEEECCCCCEEEEEEECCCEEEEEEEEECCCCHHH
FARAKELTQESSCYIHGTLRADERSSLGFELDVTDIEIVHLTQNYPITPKEHGTQFLMEH
HHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCEEEEEEEECCCCCCCHHHHHHHHHHH
RHLWVRSAKQHALLRIRAQVIAAAQEYLNSEHFVRYDSPILTATAAEGTSDLFATEYFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCHHHHHHHHHC
GNAYLAQTGQLYVESGMATFGRVYCFGPTFRAEKSKTRRHLTEFWMIEPEFAFADQDDNM
CCHHHHCCCCEEEECCCHHHCEEEEECCCCCCHHHHHHHHHHHHEEECCCEEECCCCCCC
ELQENFVSYIVQRVLDRCEEDLKILERDTSKLENIVPPFPRISYDEAIEKIKQGVAAGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCE
VAPDNAPLADLEWGDDFGAPHETYLASLFDKPLFIYNYPTKVKAFYMQPAEGRPEVVRCA
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCCHHHHHH
DLIAPEGYGEIIGGSQRIHDAELLEARIREHGLDVADYQWYLDLRRYGSVPHSGFGMGIE
HHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
RCVAWLAGTRHIREAIPFPRQLYRIYP
HHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
ALLPSMYIRDSADHVGEAVKLAGWVYHKTEKGKLVFIQLRDGTATIQCVVFKKNVSEEV
CCCCCHHHCCCHHHHHHHHHHHHHEEEECCCCCEEEEEEECCCEEEEEEEEECCCCHHH
FARAKELTQESSCYIHGTLRADERSSLGFELDVTDIEIVHLTQNYPITPKEHGTQFLMEH
HHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCEEEEEEEECCCCCCCHHHHHHHHHHH
RHLWVRSAKQHALLRIRAQVIAAAQEYLNSEHFVRYDSPILTATAAEGTSDLFATEYFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCHHHHHHHHHC
GNAYLAQTGQLYVESGMATFGRVYCFGPTFRAEKSKTRRHLTEFWMIEPEFAFADQDDNM
CCHHHHCCCCEEEECCCHHHCEEEEECCCCCCHHHHHHHHHHHHEEECCCEEECCCCCCC
ELQENFVSYIVQRVLDRCEEDLKILERDTSKLENIVPPFPRISYDEAIEKIKQGVAAGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCE
VAPDNAPLADLEWGDDFGAPHETYLASLFDKPLFIYNYPTKVKAFYMQPAEGRPEVVRCA
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCCHHHHHH
DLIAPEGYGEIIGGSQRIHDAELLEARIREHGLDVADYQWYLDLRRYGSVPHSGFGMGIE
HHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
RCVAWLAGTRHIREAIPFPRQLYRIYP
HHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA