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The map label for this gene is phoB [C]

Identifier: 159898879

GI number: 159898879

Start: 3006367

End: 3007062

Strand: Reverse

Name: phoB [C]

Synonym: Haur_2358

Alternate gene names: 159898879

Gene position: 3007062-3006367 (Counterclockwise)

Preceding gene: 159898880

Following gene: 159898878

Centisome position: 47.38

GC content: 46.84

Gene sequence:

>696_bases
ATGGCTCAGACAATTCTGGTTATCGATGATGAAGCAAAGTTACGTGAATTATTACGCAGCTATCTACAAAATGAGGGCTT
TAATGTTTTTGAGGCCAAGAATGGCCGTGAAGGTTTGTATGTCGCCCGTGATGTTAAACCCGATTTGATTTTGCTCGATA
TTATGATGCCCGAACTTGGTGGCCTCGATTTTATGCGAGCTTGGAATAAAGAAGCTGAAACGCCAATTATTTTATTAACT
GCCAAAATTGAAGATCACGATAAAATTATTGGTTTAGAACTAGGCGCTGATGATTATATTACCAAGCCATTTAATGCACG
CGAAGTGATGGCACGGGTTCGTGCGGTGCTGCGCCGTAGCTACAAAGCTCAGCCCCAAGCCGATGTACTGCGAATTGGTG
AGATTGTGCTGGAGCGTTCGGCTTGTACCTTGATGGTTGGCGAACAAACTGTTGATCTTACGCCCTCGGAATTTGAAATT
CTAGCAACCTTGATGGCCTCGCCTGGCCACGTTTTTTCGCGCCTGGATTTGCTCGATCGCACCTCGGGGCAGGCTTACGA
AGGCTATGAACGCACCATCGATGTGCATATTCGCAATTTGCGCAGCAAAATCGAGCCAGACCCGAAAAATCCGCGCTATA
TCGAAACTGTGTATGGGGTTGGCTATCGTTTTGCCCGCCCGAAACGGCCTGAATGA

Upstream 100 bases:

>100_bases
TCGCCGCGATATTGTATGGCTCTAGCTGCTCGGTTGTAAGGCGCGACGATCCCCCAGCGTTGCGCCTTTTGAACCCGTTG
CGGGAGATTGGAAACGCACA

Downstream 100 bases:

>100_bases
TGATGTTACGCTCACTGACATGGAAATTAACCCTCGCTTTTTTGGGGGTCGGCTTGATTGGGGCTGTGGTCGTGGCCTTG
TTGGCGCGGCAGAGTGCCCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAQTILVIDDEAKLRELLRSYLQNEGFNVFEAKNGREGLYVARDVKPDLILLDIMMPELGGLDFMRAWNKEAETPIILLT
AKIEDHDKIIGLELGADDYITKPFNAREVMARVRAVLRRSYKAQPQADVLRIGEIVLERSACTLMVGEQTVDLTPSEFEI
LATLMASPGHVFSRLDLLDRTSGQAYEGYERTIDVHIRNLRSKIEPDPKNPRYIETVYGVGYRFARPKRPE

Sequences:

>Translated_231_residues
MAQTILVIDDEAKLRELLRSYLQNEGFNVFEAKNGREGLYVARDVKPDLILLDIMMPELGGLDFMRAWNKEAETPIILLT
AKIEDHDKIIGLELGADDYITKPFNAREVMARVRAVLRRSYKAQPQADVLRIGEIVLERSACTLMVGEQTVDLTPSEFEI
LATLMASPGHVFSRLDLLDRTSGQAYEGYERTIDVHIRNLRSKIEPDPKNPRYIETVYGVGYRFARPKRPE
>Mature_230_residues
AQTILVIDDEAKLRELLRSYLQNEGFNVFEAKNGREGLYVARDVKPDLILLDIMMPELGGLDFMRAWNKEAETPIILLTA
KIEDHDKIIGLELGADDYITKPFNAREVMARVRAVLRRSYKAQPQADVLRIGEIVLERSACTLMVGEQTVDLTPSEFEIL
ATLMASPGHVFSRLDLLDRTSGQAYEGYERTIDVHIRNLRSKIEPDPKNPRYIETVYGVGYRFARPKRPE

Specific function: This Protein Is A Positive Regulator For The Phosphate Regulon. Transcription Of This Operon Is Positively Regulated By Phob And Phor When Phosphate Is Limited. [C]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40, Blast_Score=168, Evalue=2e-43,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=41.1504424778761, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=36.6515837104072, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=41.0480349344978, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=38.4615384615385, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=39.5555555555556, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=36.2445414847162, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32.4444444444444, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=35.9307359307359, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=34.375, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.6846846846847, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=31.0810810810811, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=32.8767123287671, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=28.4518828451883, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=37.7049180327869, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI87082052, Length=203, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=30.6451612903226, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26352; Mature: 26221

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTILVIDDEAKLRELLRSYLQNEGFNVFEAKNGREGLYVARDVKPDLILLDIMMPELG
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCEEEEEECCCCCC
GLDFMRAWNKEAETPIILLTAKIEDHDKIIGLELGADDYITKPFNAREVMARVRAVLRRS
CHHHHHHCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
YKAQPQADVLRIGEIVLERSACTLMVGEQTVDLTPSEFEILATLMASPGHVFSRLDLLDR
HCCCCCHHHHHHHHHHHHCCCEEEEECCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHC
TSGQAYEGYERTIDVHIRNLRSKIEPDPKNPRYIETVYGVGYRFARPKRPE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCEEECCCCCCC
>Mature Secondary Structure 
AQTILVIDDEAKLRELLRSYLQNEGFNVFEAKNGREGLYVARDVKPDLILLDIMMPELG
CCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCEEEEEECCCCCC
GLDFMRAWNKEAETPIILLTAKIEDHDKIIGLELGADDYITKPFNAREVMARVRAVLRRS
CHHHHHHCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
YKAQPQADVLRIGEIVLERSACTLMVGEQTVDLTPSEFEILATLMASPGHVFSRLDLLDR
HCCCCCHHHHHHHHHHHHCCCEEEEECCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHC
TSGQAYEGYERTIDVHIRNLRSKIEPDPKNPRYIETVYGVGYRFARPKRPE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]