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The map label for this gene is cobB [H]

Identifier: 159898850

GI number: 159898850

Start: 2972165

End: 2973529

Strand: Direct

Name: cobB [H]

Synonym: Haur_2329

Alternate gene names: 159898850

Gene position: 2972165-2973529 (Clockwise)

Preceding gene: 159898849

Following gene: 159898852

Centisome position: 46.83

GC content: 53.04

Gene sequence:

>1365_bases
TTGACTGCCCGTGTGATTATTGCTGCCGCCCATAGTGGCAGCGGCAAAACCTTGTTAACTGCTGGCTTGATTGGGGCGAT
TCGGCGGCTGGGCCTTAACGTTCAGCCCTTTAAATGTGGCCCCGATTATATCGATCCTGGCCATCATAGCTTAGTTGCCC
AGCGCCCGTGTCGCAATTTGGATGCCTGGTTATTTACGCCAGAGCAATTGCAACGCCATTTTTGCCAAATCGCTGCCCCT
GCCGATCTGGCAATTATCGAGGGCGTGATGGGGCTATTCGATGGCTATGGCGCACTCGATGATACTGGCAGCACCGCCCA
TATCGCCCGCTTATTGCAAGCACCAGTCGTTTTGGTGGTCGATGCTGGCGGCATGGCCCGCAGCGCCGCCGCCGTAGTAG
CAGGTTTTCAGCACTTCGATCCACAGGTGCAGATCGGCGGGGTGTTGCTGAACAAGGTTGGCAGCGCACGCCATGCCGAT
TTATGTGCTACAGCGATTGAGCAACACACCGGCATTAAATGCTTGGGCTATTTGCCCCGCCAAGCTCAATTCAACCTACC
TGAACGTCATCTCGGTTTAGTAACTGCTGAATCTGCGAAGCAGACTATTTTAGAAACGCTTGATGCAGTGGCAACGACGC
TAAGCAGCACCTGCCAGCTTGAGCAATTGGTCAGTTTAGCCCAAAGTGCCCCACCAATTCAGTTAGAGCCACTGCCAATC
AGCCCAATTGAGTATGCACAGCGGCCAGTCATTGCAGTGGCTTATGACGCAGCATTTAGTTTTATCTACCCTGAGATGCA
AGAATGTTTGCAGGCCGCCGGAGCCGAAATCGCCTTATTCAGCCCAATCGCCGATCAGCAGTTGCCCACCAATTGCGCTG
GAATCATTTTGAGTGGCGGCTATCCTGAGTTGTATGCTGCTGAGTTGAGCACTAATCAGGCCATGCTCAATGCATTACGT
CAAGCTCATGCTGCGAATGTGCCGATGTATGCTGAATGTGGCGGGCTGATGTACTTGACCGAGGCGATTGTTGATCAAGC
AGGTCAGCCTTGGCCGATGGTAGGTTTACTGCCAGGCAGCAGCCAGATGCATCAAAAAGTCAGTTTGGGCTATCGCACAA
TCAGCGTTTGCAATGATAATCCCTTGTTCAGTGCTAACAGCCAAGTGCGCGGCCATGAATTCCACTATTCGCGCTGGGAA
AACCCTGAGCCAGCCACAGCAGCCTATTGCATAATTGCGCCCGACGGCACGCCTCAGCAGCATGAAGGCTACCAAGCTGG
CAATTTACTAGCAAGTTATATCCATCTGCATTGGCTAGCCAACCCAAGCATGGCCCAACGGTTCGTTGCCTCGTGCTGTT
CTTGA

Upstream 100 bases:

>100_bases
CAGAAGAAGCCGCCGCCAGCCATAGCTAAATTGGTCAATTAATCAAGTTTGCCAAGCATCAGCAATTGGTGCTTGGCTTT
TTTGTGGATAGGAGTATTGT

Downstream 100 bases:

>100_bases
TAACATTATGGGAATAGGTTTTTAATGCTTCACTAGGGAGCACGGCTGGGAACGGGGCTAGGTAATAGGTATCATGGTTC
ATTGGGCCTCTCACCCCCAG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTARVIIAAAHSGSGKTLLTAGLIGAIRRLGLNVQPFKCGPDYIDPGHHSLVAQRPCRNLDAWLFTPEQLQRHFCQIAAP
ADLAIIEGVMGLFDGYGALDDTGSTAHIARLLQAPVVLVVDAGGMARSAAAVVAGFQHFDPQVQIGGVLLNKVGSARHAD
LCATAIEQHTGIKCLGYLPRQAQFNLPERHLGLVTAESAKQTILETLDAVATTLSSTCQLEQLVSLAQSAPPIQLEPLPI
SPIEYAQRPVIAVAYDAAFSFIYPEMQECLQAAGAEIALFSPIADQQLPTNCAGIILSGGYPELYAAELSTNQAMLNALR
QAHAANVPMYAECGGLMYLTEAIVDQAGQPWPMVGLLPGSSQMHQKVSLGYRTISVCNDNPLFSANSQVRGHEFHYSRWE
NPEPATAAYCIIAPDGTPQQHEGYQAGNLLASYIHLHWLANPSMAQRFVASCCS

Sequences:

>Translated_454_residues
MTARVIIAAAHSGSGKTLLTAGLIGAIRRLGLNVQPFKCGPDYIDPGHHSLVAQRPCRNLDAWLFTPEQLQRHFCQIAAP
ADLAIIEGVMGLFDGYGALDDTGSTAHIARLLQAPVVLVVDAGGMARSAAAVVAGFQHFDPQVQIGGVLLNKVGSARHAD
LCATAIEQHTGIKCLGYLPRQAQFNLPERHLGLVTAESAKQTILETLDAVATTLSSTCQLEQLVSLAQSAPPIQLEPLPI
SPIEYAQRPVIAVAYDAAFSFIYPEMQECLQAAGAEIALFSPIADQQLPTNCAGIILSGGYPELYAAELSTNQAMLNALR
QAHAANVPMYAECGGLMYLTEAIVDQAGQPWPMVGLLPGSSQMHQKVSLGYRTISVCNDNPLFSANSQVRGHEFHYSRWE
NPEPATAAYCIIAPDGTPQQHEGYQAGNLLASYIHLHWLANPSMAQRFVASCCS
>Mature_453_residues
TARVIIAAAHSGSGKTLLTAGLIGAIRRLGLNVQPFKCGPDYIDPGHHSLVAQRPCRNLDAWLFTPEQLQRHFCQIAAPA
DLAIIEGVMGLFDGYGALDDTGSTAHIARLLQAPVVLVVDAGGMARSAAAVVAGFQHFDPQVQIGGVLLNKVGSARHADL
CATAIEQHTGIKCLGYLPRQAQFNLPERHLGLVTAESAKQTILETLDAVATTLSSTCQLEQLVSLAQSAPPIQLEPLPIS
PIEYAQRPVIAVAYDAAFSFIYPEMQECLQAAGAEIALFSPIADQQLPTNCAGIILSGGYPELYAAELSTNQAMLNALRQ
AHAANVPMYAECGGLMYLTEAIVDQAGQPWPMVGLLPGSSQMHQKVSLGYRTISVCNDNPLFSANSQVRGHEFHYSRWEN
PEPATAAYCIIAPDGTPQQHEGYQAGNLLASYIHLHWLANPSMAQRFVASCCS

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 48556; Mature: 48425

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARVIIAAAHSGSGKTLLTAGLIGAIRRLGLNVQPFKCGPDYIDPGHHSLVAQRPCRNL
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCC
DAWLFTPEQLQRHFCQIAAPADLAIIEGVMGLFDGYGALDDTGSTAHIARLLQAPVVLVV
CCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEE
DAGGMARSAAAVVAGFQHFDPQVQIGGVLLNKVGSARHADLCATAIEQHTGIKCLGYLPR
CCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCC
QAQFNLPERHLGLVTAESAKQTILETLDAVATTLSSTCQLEQLVSLAQSAPPIQLEPLPI
CCCCCCCHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCC
SPIEYAQRPVIAVAYDAAFSFIYPEMQECLQAAGAEIALFSPIADQQLPTNCAGIILSGG
CHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEECC
YPELYAAELSTNQAMLNALRQAHAANVPMYAECGGLMYLTEAIVDQAGQPWPMVGLLPGS
CCCEEEEHHCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHCCCCCCCEEEECCCC
SQMHQKVSLGYRTISVCNDNPLFSANSQVRGHEFHYSRWENPEPATAAYCIIAPDGTPQQ
HHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
HEGYQAGNLLASYIHLHWLANPSMAQRFVASCCS
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TARVIIAAAHSGSGKTLLTAGLIGAIRRLGLNVQPFKCGPDYIDPGHHSLVAQRPCRNL
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCC
DAWLFTPEQLQRHFCQIAAPADLAIIEGVMGLFDGYGALDDTGSTAHIARLLQAPVVLVV
CCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEE
DAGGMARSAAAVVAGFQHFDPQVQIGGVLLNKVGSARHADLCATAIEQHTGIKCLGYLPR
CCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCC
QAQFNLPERHLGLVTAESAKQTILETLDAVATTLSSTCQLEQLVSLAQSAPPIQLEPLPI
CCCCCCCHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCC
SPIEYAQRPVIAVAYDAAFSFIYPEMQECLQAAGAEIALFSPIADQQLPTNCAGIILSGG
CHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEECC
YPELYAAELSTNQAMLNALRQAHAANVPMYAECGGLMYLTEAIVDQAGQPWPMVGLLPGS
CCCEEEEHHCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHCCCCCCCEEEECCCC
SQMHQKVSLGYRTISVCNDNPLFSANSQVRGHEFHYSRWENPEPATAAYCIIAPDGTPQQ
HHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
HEGYQAGNLLASYIHLHWLANPSMAQRFVASCCS
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA