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The map label for this gene is rsbRA [H]

Identifier: 159898817

GI number: 159898817

Start: 2936630

End: 2937658

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_2296

Alternate gene names: 159898817

Gene position: 2936630-2937658 (Clockwise)

Preceding gene: 159898815

Following gene: 159898819

Centisome position: 46.27

GC content: 50.53

Gene sequence:

>1029_bases
ATGGCCGATCGTCAAATTGCCCTCTGGAATGAAGAACGTGAACAGCGCAAGCGAGCCTTGCAACGTATTTTGATTACTGG
CAGTAGTTTTATTTTCCTACTGATTTTATATTATGTGTTCGGGGTTGATCTCAGTGTTGGCCGCAATCAGCTAGCGCTCG
GCTGTTTGATTGGAGTGCTGGTTGCCGCCGCGATTTCGGGCTGGCTGGTCAGCATCGATCAGCCAGAATGGGCCACCCAC
GCGATGTTTATTCCCTACATGCTGATTATTTTGGTGGTGGCAACTCCGGTCGGGGTAACGAGCCGTGGCATGTATGGGTT
ATTTATTCCAATTGTAGCGGCGGCACTGCTCTTGCCAGCCCGTTGGAGTCTAATTTATGCAGCGCTGGCAGTGGTAGTTT
TCGTCAGCACCGATATGTTAAGCCCTCAGCCATTTTCATTAAATACAACTATTCTGAATACATTGTTCGCAGGCGGATGT
TTTGGCACCGCCGCCGCTACCACTTCGTTTACTGCCCGCCGCTTACGCCAATTGCTCAAAACTAGCATTGAACATAGCAA
GGAGCTTGAGCGCAATCAGGCGGTGCTTGAGGAACGAGTACAAAAACGCACGCTGTATCTTGAAAAAGCGCTCGATGAAT
TACAACGCTCCAGCGAGACGATTCGCCAAATGAGTGTACCAGTGCTGCCAATCGCCGAACGGGTTTTGGTGTTGCCGCTG
GTTGGCAGCATTGACCTCTCACGGGCGGCCTTGCTCAGCGATGAACTGCTGAATACAATCTATCAACGCCGCCCACATAC
AATTTTGATCGACTTAACGGGATTAACGACGATTGATCAGGTGGTGGCTGAATCGTTGGTACAAACCTTGAGTGCGGTGC
GCTTGCTTGGCACCGAGCCAATTGTGGTTGGTTTACGCAGCGAAACCGTCCAAGCCTTGCTCGATACCGGCATTGATATC
AGCCATATTCGCACCTTCCGCGATGTGCAAAGTGGGCTGGGTTACGCCACCAGCAAAATTAGTTATTAA

Upstream 100 bases:

>100_bases
GATTATAGCACAGACGGTCGCATGCAGGCAGGCTTGAATCATCAGCAAAAAAGCCTGTTATAATGCGCCATGCCCAATTT
ACTCAATAGGTATACCGCGC

Downstream 100 bases:

>100_bases
GTTCCTGCCCATCATATTTACAAAGGTCTTACGATCACCACCCTTCCGTCCCGCCTCAAGGCGGGAAACGCCAGGGGCTT
TAATCCCCCGGCACCCCCTC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MADRQIALWNEEREQRKRALQRILITGSSFIFLLILYYVFGVDLSVGRNQLALGCLIGVLVAAAISGWLVSIDQPEWATH
AMFIPYMLIILVVATPVGVTSRGMYGLFIPIVAAALLLPARWSLIYAALAVVVFVSTDMLSPQPFSLNTTILNTLFAGGC
FGTAAATTSFTARRLRQLLKTSIEHSKELERNQAVLEERVQKRTLYLEKALDELQRSSETIRQMSVPVLPIAERVLVLPL
VGSIDLSRAALLSDELLNTIYQRRPHTILIDLTGLTTIDQVVAESLVQTLSAVRLLGTEPIVVGLRSETVQALLDTGIDI
SHIRTFRDVQSGLGYATSKISY

Sequences:

>Translated_342_residues
MADRQIALWNEEREQRKRALQRILITGSSFIFLLILYYVFGVDLSVGRNQLALGCLIGVLVAAAISGWLVSIDQPEWATH
AMFIPYMLIILVVATPVGVTSRGMYGLFIPIVAAALLLPARWSLIYAALAVVVFVSTDMLSPQPFSLNTTILNTLFAGGC
FGTAAATTSFTARRLRQLLKTSIEHSKELERNQAVLEERVQKRTLYLEKALDELQRSSETIRQMSVPVLPIAERVLVLPL
VGSIDLSRAALLSDELLNTIYQRRPHTILIDLTGLTTIDQVVAESLVQTLSAVRLLGTEPIVVGLRSETVQALLDTGIDI
SHIRTFRDVQSGLGYATSKISY
>Mature_341_residues
ADRQIALWNEEREQRKRALQRILITGSSFIFLLILYYVFGVDLSVGRNQLALGCLIGVLVAAAISGWLVSIDQPEWATHA
MFIPYMLIILVVATPVGVTSRGMYGLFIPIVAAALLLPARWSLIYAALAVVVFVSTDMLSPQPFSLNTTILNTLFAGGCF
GTAAATTSFTARRLRQLLKTSIEHSKELERNQAVLEERVQKRTLYLEKALDELQRSSETIRQMSVPVLPIAERVLVLPLV
GSIDLSRAALLSDELLNTIYQRRPHTILIDLTGLTTIDQVVAESLVQTLSAVRLLGTEPIVVGLRSETVQALLDTGIDIS
HIRTFRDVQSGLGYATSKISY

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 37707; Mature: 37576

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRQIALWNEEREQRKRALQRILITGSSFIFLLILYYVFGVDLSVGRNQLALGCLIGVL
CCCCCEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
VAAAISGWLVSIDQPEWATHAMFIPYMLIILVVATPVGVTSRGMYGLFIPIVAAALLLPA
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RWSLIYAALAVVVFVSTDMLSPQPFSLNTTILNTLFAGGCFGTAAATTSFTARRLRQLLK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TSIEHSKELERNQAVLEERVQKRTLYLEKALDELQRSSETIRQMSVPVLPIAERVLVLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VGSIDLSRAALLSDELLNTIYQRRPHTILIDLTGLTTIDQVVAESLVQTLSAVRLLGTEP
HCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
IVVGLRSETVQALLDTGIDISHIRTFRDVQSGLGYATSKISY
EEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure 
ADRQIALWNEEREQRKRALQRILITGSSFIFLLILYYVFGVDLSVGRNQLALGCLIGVL
CCCCEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
VAAAISGWLVSIDQPEWATHAMFIPYMLIILVVATPVGVTSRGMYGLFIPIVAAALLLPA
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RWSLIYAALAVVVFVSTDMLSPQPFSLNTTILNTLFAGGCFGTAAATTSFTARRLRQLLK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TSIEHSKELERNQAVLEERVQKRTLYLEKALDELQRSSETIRQMSVPVLPIAERVLVLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VGSIDLSRAALLSDELLNTIYQRRPHTILIDLTGLTTIDQVVAESLVQTLSAVRLLGTEP
HCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
IVVGLRSETVQALLDTGIDISHIRTFRDVQSGLGYATSKISY
EEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]