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The map label for this gene is soxB [H]

Identifier: 159898802

GI number: 159898802

Start: 2921794

End: 2922951

Strand: Reverse

Name: soxB [H]

Synonym: Haur_2281

Alternate gene names: 159898802

Gene position: 2922951-2921794 (Counterclockwise)

Preceding gene: 159898803

Following gene: 159898801

Centisome position: 46.06

GC content: 51.81

Gene sequence:

>1158_bases
ATGGTTCACCAAGCACAGGTTGTCGTTATTGGGGCAGGCATCATTGGGGCTTCTGTTGCCTACCATCTTGCTGCGCGGGG
CTGTACCGAGGTAGTGGTGTTAGAAAAAGAGGCGGTTGAGGTTACTGGCTCGACTGCTCGTTCTGCGGCTGGGGTTCGCC
ATCAGTTCTCATCACGCACCAATATCTTACTTTCCCAATATAGCATCGAACGCTACAAACATTTTACCGAAGAAATTGGC
GGCCATGCCGAATTACATCAACATGGCTATCTCTTTTTGTTTAATGATTCCGCTACCTGGCAAGCCTACCAAGCGGTGCT
CGAATTGCAACGTAGCTTAAATGTACCAGTGCAGGTGCTTACGCCAGAACAGGCCGCTGGCTATATTCCCGAATTAAATA
TTAGCGATATCGTTGGCGCAACCTATTGTGCCGAAGATGGCTTTGTTGACCCGCATGGCATTGCAATGGGCTATTTGAAC
AAAGCCCGAGAGTTGGGCGTGAAGGTTTTACGCGATGCTCCGGCGTTGGGCTTTGAATTTGCCGATGATCAGGTGGTTGG
GGTGCAAACACCCCAAGGCACGATTCATTGCAAGTATGTGGTCAATGCTGCTGGCCCTTATGCTGGCGAGGTTGGCAAAA
CCGCTGGCTTCGAGATTCCGATCAAGCCGTATCGCCGCTGCATCTATGTTTCCGATCCATTTCCGGCCTTGCCCAAGGAT
ATTCCGCTAACAATTGATGTTGGCACGGGAGCCTATATTCGCAAAGAGCAAGAGACGGTGCTGATGGGCTTGAGTAATCT
CAACGAGCCATCATCACACGATACAACGGTCGATTGGGATTGGCTGGATACGGTCTTGGAAGCCATGCTCAATCGTTTTC
CAATTTTGGAGCGGGCGGGGCTTTCCGAGCGCCAATCGTGGGCTGGCTCGTATGAAATTACGCCCGACCACCTACCTATT
TTAGGCCGGATGCCCAATTGCCCTAATTGGCTGAATGCCGCCGGATTTAGCGGCCATGGCGTGATGCATGCGCCCGCGAC
TGGTTTGCTGATTGCCGAAGAAATTCTTGATGGCCGCGCTCACTCAATCGAGATTGACGAGCTGCGAATCGAACGCTTTG
CTGCTGGCGAACTACACGCTGAGCGCAATGTAATCTAG

Upstream 100 bases:

>100_bases
CAATAGTACAGCCATTTTGGGCTAAAATCAGCCGCCACGCCATAGCATCCTTTGGTACAATAGTGCAAACATCATTGCAC
ATCAAAGGAGATCGTTCGGA

Downstream 100 bases:

>100_bases
GGGTGTTTCAAGCCTGCGTCGGTTGAGGCAGGCGCAGGCTTGAATGGAGTGTTGAGCAACGCCTATGCAGAGTATCGACA
AACTATTTGTAAACCGCGAA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MVHQAQVVVIGAGIIGASVAYHLAARGCTEVVVLEKEAVEVTGSTARSAAGVRHQFSSRTNILLSQYSIERYKHFTEEIG
GHAELHQHGYLFLFNDSATWQAYQAVLELQRSLNVPVQVLTPEQAAGYIPELNISDIVGATYCAEDGFVDPHGIAMGYLN
KARELGVKVLRDAPALGFEFADDQVVGVQTPQGTIHCKYVVNAAGPYAGEVGKTAGFEIPIKPYRRCIYVSDPFPALPKD
IPLTIDVGTGAYIRKEQETVLMGLSNLNEPSSHDTTVDWDWLDTVLEAMLNRFPILERAGLSERQSWAGSYEITPDHLPI
LGRMPNCPNWLNAAGFSGHGVMHAPATGLLIAEEILDGRAHSIEIDELRIERFAAGELHAERNVI

Sequences:

>Translated_385_residues
MVHQAQVVVIGAGIIGASVAYHLAARGCTEVVVLEKEAVEVTGSTARSAAGVRHQFSSRTNILLSQYSIERYKHFTEEIG
GHAELHQHGYLFLFNDSATWQAYQAVLELQRSLNVPVQVLTPEQAAGYIPELNISDIVGATYCAEDGFVDPHGIAMGYLN
KARELGVKVLRDAPALGFEFADDQVVGVQTPQGTIHCKYVVNAAGPYAGEVGKTAGFEIPIKPYRRCIYVSDPFPALPKD
IPLTIDVGTGAYIRKEQETVLMGLSNLNEPSSHDTTVDWDWLDTVLEAMLNRFPILERAGLSERQSWAGSYEITPDHLPI
LGRMPNCPNWLNAAGFSGHGVMHAPATGLLIAEEILDGRAHSIEIDELRIERFAAGELHAERNVI
>Mature_385_residues
MVHQAQVVVIGAGIIGASVAYHLAARGCTEVVVLEKEAVEVTGSTARSAAGVRHQFSSRTNILLSQYSIERYKHFTEEIG
GHAELHQHGYLFLFNDSATWQAYQAVLELQRSLNVPVQVLTPEQAAGYIPELNISDIVGATYCAEDGFVDPHGIAMGYLN
KARELGVKVLRDAPALGFEFADDQVVGVQTPQGTIHCKYVVNAAGPYAGEVGKTAGFEIPIKPYRRCIYVSDPFPALPKD
IPLTIDVGTGAYIRKEQETVLMGLSNLNEPSSHDTTVDWDWLDTVLEAMLNRFPILERAGLSERQSWAGSYEITPDHLPI
LGRMPNCPNWLNAAGFSGHGVMHAPATGLLIAEEILDGRAHSIEIDELRIERFAAGELHAERNVI

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=385, Percent_Identity=28.051948051948, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI21361378, Length=385, Percent_Identity=28.051948051948, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI24797151, Length=395, Percent_Identity=28.8607594936709, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI8923708, Length=414, Percent_Identity=28.2608695652174, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI194306651, Length=405, Percent_Identity=28.8888888888889, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541536, Length=427, Percent_Identity=26.2295081967213, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71994045, Length=401, Percent_Identity=23.9401496259352, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71994052, Length=408, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20129729, Length=414, Percent_Identity=31.1594202898551, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28571104, Length=398, Percent_Identity=27.3869346733668, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20130091, Length=369, Percent_Identity=27.9132791327913, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17985989, Length=408, Percent_Identity=26.2254901960784, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42050; Mature: 42050

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHQAQVVVIGAGIIGASVAYHLAARGCTEVVVLEKEAVEVTGSTARSAAGVRHQFSSRT
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCHHHHHHHHHHHHCCCC
NILLSQYSIERYKHFTEEIGGHAELHQHGYLFLFNDSATWQAYQAVLELQRSLNVPVQVL
EEEEEHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEE
TPEQAAGYIPELNISDIVGATYCAEDGFVDPHGIAMGYLNKARELGVKVLRDAPALGFEF
CCHHHCCCCCCCCHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ADDQVVGVQTPQGTIHCKYVVNAAGPYAGEVGKTAGFEIPIKPYRRCIYVSDPFPALPKD
CCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
IPLTIDVGTGAYIRKEQETVLMGLSNLNEPSSHDTTVDWDWLDTVLEAMLNRFPILERAG
CCEEEECCCCCEEECCCCEEEEEHHCCCCCCCCCCEECHHHHHHHHHHHHHHCCCHHHCC
LSERQSWAGSYEITPDHLPILGRMPNCPNWLNAAGFSGHGVMHAPATGLLIAEEILDGRA
CCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHCCCC
HSIEIDELRIERFAAGELHAERNVI
CEEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVHQAQVVVIGAGIIGASVAYHLAARGCTEVVVLEKEAVEVTGSTARSAAGVRHQFSSRT
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCHHHHHHHHHHHHCCCC
NILLSQYSIERYKHFTEEIGGHAELHQHGYLFLFNDSATWQAYQAVLELQRSLNVPVQVL
EEEEEHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEE
TPEQAAGYIPELNISDIVGATYCAEDGFVDPHGIAMGYLNKARELGVKVLRDAPALGFEF
CCHHHCCCCCCCCHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ADDQVVGVQTPQGTIHCKYVVNAAGPYAGEVGKTAGFEIPIKPYRRCIYVSDPFPALPKD
CCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
IPLTIDVGTGAYIRKEQETVLMGLSNLNEPSSHDTTVDWDWLDTVLEAMLNRFPILERAG
CCEEEECCCCCEEECCCCEEEEEHHCCCCCCCCCCEECHHHHHHHHHHHHHHCCCHHHCC
LSERQSWAGSYEITPDHLPILGRMPNCPNWLNAAGFSGHGVMHAPATGLLIAEEILDGRA
CCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHCCCCCCCCEEECCCCCHHHHHHHHCCCC
HSIEIDELRIERFAAGELHAERNVI
CEEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]