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The map label for this gene is capA [H]

Identifier: 159898763

GI number: 159898763

Start: 2858501

End: 2859625

Strand: Direct

Name: capA [H]

Synonym: Haur_2242

Alternate gene names: 159898763

Gene position: 2858501-2859625 (Clockwise)

Preceding gene: 159898759

Following gene: 159898764

Centisome position: 45.04

GC content: 51.2

Gene sequence:

>1125_bases
ATGCGACGTTTGAGTTTTTGGATACTCTTAGGAATAATTTTAGCAGCCTGCGGGAGCAGCACGCCCACCACTGAGCCAAG
CCAATTGGCACTTGCCCCAACCGCAACGATTGCGGTAACTGTAACCGCCGCACCAACCAACTCTCCCGAACCAACCAGTA
CAACCCTGCCAACCGTAACCACTGAGCCAAGCCCAACCCCTGAACCTAAAATCGAATTGGCAGTGGTTGGTGATATTATG
CTAGCTCGCTCGATCGGCGAGCGCATTCTTAGCGATAGCCCTGAGCAGCCCTTTGCCGGAGTGCGCGATGAATTAGTTAA
TGCCGACCTGACGATTGGCAATCTTGAAACGGCAATTGCTGATGCTGGCGAACCTGCGCCCAAAGCCTACCGTTTTTTAG
CGCCCCCCGAAAGTGTTGATAGCCTTAGCGATGCAGGCTTTGATCTAGTTTCGCTGGCCAATAATCATAGCCTCGATTGG
GGTGAATCGGCTTTAAGCGAGACAATTGGCCTATTGAATGAGGCTGAGATTGCCAATGTTGGTGCAGGCATGAACGCCGA
ACAGGCCTATCGTCCAGTTATTATCGAGAAACATGGCTTGCGTTTGGCGTTTCTGGCCTATGTGAATGTGCCAGTTGAGC
GTGGCGGATTTGTAACCGAATCGTGGACAGCCACTGCCGAACAAGCAGGCTTGGCTTGGGCCGAACCAGCAGTGATCGCG
GCTGATGTCGCGGCAATTCGGCCAAGCGTCGATCATGTGATTATCTTGCTGCATAGCGGCTATGAAGGGATTGATCAACC
AAATGAGATTCAGCGAAGCAATGCCTATGCGGCACTCGACGCTGGCGCAACCTTAGTTTTGGGTGCACATCCGCACGTGT
TGCAAGGCTATGAAGCCCGCCCGAATGGCCAATTTATTGCTTGGAGTTTGGGCAATTTTGTATTTGATGGCTTCGATGGT
ACACCTAGTCTTGATAGTGCCATTTTACATTTGACCCTCGATAAAACGAGAGTCATCGCCTCACGCTGGACACCAGTCCG
CTTGATCGATGGCTATCCACAGGCGCTCGATCCCACAACTGATGGAGCCTATATCATTGAAAAAATTGAGCAATTGAGCA
ATTAA

Upstream 100 bases:

>100_bases
ATATTCGCGCATTGTGGACATACACATTATACATCGCCTACAATTAACTCCTATGCTACTCTATCGCTACAGCAACTCGT
TAAACAGGAAGGATGTTTGT

Downstream 100 bases:

>100_bases
TCCATCAAGTACACTCGACATTCCTCCGCACACTATCCAAAAAGTACCATACCTGGAACCATTCTCAGGTTAAGACCTGA
GAATGGTTCCAATCAAGGCC

Product: putative poly-gamma-glutamate biosynthesis (capsule formation)-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRRLSFWILLGIILAACGSSTPTTEPSQLALAPTATIAVTVTAAPTNSPEPTSTTLPTVTTEPSPTPEPKIELAVVGDIM
LARSIGERILSDSPEQPFAGVRDELVNADLTIGNLETAIADAGEPAPKAYRFLAPPESVDSLSDAGFDLVSLANNHSLDW
GESALSETIGLLNEAEIANVGAGMNAEQAYRPVIIEKHGLRLAFLAYVNVPVERGGFVTESWTATAEQAGLAWAEPAVIA
ADVAAIRPSVDHVIILLHSGYEGIDQPNEIQRSNAYAALDAGATLVLGAHPHVLQGYEARPNGQFIAWSLGNFVFDGFDG
TPSLDSAILHLTLDKTRVIASRWTPVRLIDGYPQALDPTTDGAYIIEKIEQLSN

Sequences:

>Translated_374_residues
MRRLSFWILLGIILAACGSSTPTTEPSQLALAPTATIAVTVTAAPTNSPEPTSTTLPTVTTEPSPTPEPKIELAVVGDIM
LARSIGERILSDSPEQPFAGVRDELVNADLTIGNLETAIADAGEPAPKAYRFLAPPESVDSLSDAGFDLVSLANNHSLDW
GESALSETIGLLNEAEIANVGAGMNAEQAYRPVIIEKHGLRLAFLAYVNVPVERGGFVTESWTATAEQAGLAWAEPAVIA
ADVAAIRPSVDHVIILLHSGYEGIDQPNEIQRSNAYAALDAGATLVLGAHPHVLQGYEARPNGQFIAWSLGNFVFDGFDG
TPSLDSAILHLTLDKTRVIASRWTPVRLIDGYPQALDPTTDGAYIIEKIEQLSN
>Mature_374_residues
MRRLSFWILLGIILAACGSSTPTTEPSQLALAPTATIAVTVTAAPTNSPEPTSTTLPTVTTEPSPTPEPKIELAVVGDIM
LARSIGERILSDSPEQPFAGVRDELVNADLTIGNLETAIADAGEPAPKAYRFLAPPESVDSLSDAGFDLVSLANNHSLDW
GESALSETIGLLNEAEIANVGAGMNAEQAYRPVIIEKHGLRLAFLAYVNVPVERGGFVTESWTATAEQAGLAWAEPAVIA
ADVAAIRPSVDHVIILLHSGYEGIDQPNEIQRSNAYAALDAGATLVLGAHPHVLQGYEARPNGQFIAWSLGNFVFDGFDG
TPSLDSAILHLTLDKTRVIASRWTPVRLIDGYPQALDPTTDGAYIIEKIEQLSN

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 39647; Mature: 39647

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLSFWILLGIILAACGSSTPTTEPSQLALAPTATIAVTVTAAPTNSPEPTSTTLPTVT
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEEEEECCCCCCCCCCCCCCEEE
TEPSPTPEPKIELAVVGDIMLARSIGERILSDSPEQPFAGVRDELVNADLTIGNLETAIA
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEECCHHHHHH
DAGEPAPKAYRFLAPPESVDSLSDAGFDLVSLANNHSLDWGESALSETIGLLNEAEIANV
CCCCCCCHHEEECCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHC
GAGMNAEQAYRPVIIEKHGLRLAFLAYVNVPVERGGFVTESWTATAEQAGLAWAEPAVIA
CCCCCHHHCCCCEEEECCCCEEEEEEEEECCHHCCCEEECCCCCHHHHCCCCCCCCCHHH
ADVAAIRPSVDHVIILLHSGYEGIDQPNEIQRSNAYAALDAGATLVLGAHPHVLQGYEAR
HHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHCCCEEEECCCCEEEEECCCHHHCCCCCC
PNGQFIAWSLGNFVFDGFDGTPSLDSAILHLTLDKTRVIASRWTPVRLIDGYPQALDPTT
CCCCEEEEECCCEEEECCCCCCCCCCEEEEEEECCCEEHHHCCCCEEEECCCCCCCCCCC
DGAYIIEKIEQLSN
CCHHHHHHHHHHCC
>Mature Secondary Structure
MRRLSFWILLGIILAACGSSTPTTEPSQLALAPTATIAVTVTAAPTNSPEPTSTTLPTVT
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEEEEECCCCCCCCCCCCCCEEE
TEPSPTPEPKIELAVVGDIMLARSIGERILSDSPEQPFAGVRDELVNADLTIGNLETAIA
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEECCHHHHHH
DAGEPAPKAYRFLAPPESVDSLSDAGFDLVSLANNHSLDWGESALSETIGLLNEAEIANV
CCCCCCCHHEEECCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHC
GAGMNAEQAYRPVIIEKHGLRLAFLAYVNVPVERGGFVTESWTATAEQAGLAWAEPAVIA
CCCCCHHHCCCCEEEECCCCEEEEEEEEECCHHCCCEEECCCCCHHHHCCCCCCCCCHHH
ADVAAIRPSVDHVIILLHSGYEGIDQPNEIQRSNAYAALDAGATLVLGAHPHVLQGYEAR
HHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHCCCEEEECCCCEEEEECCCHHHCCCCCC
PNGQFIAWSLGNFVFDGFDGTPSLDSAILHLTLDKTRVIASRWTPVRLIDGYPQALDPTT
CCCCEEEEECCCEEEECCCCCCCCCCEEEEEEECCCEEHHHCCCCEEEECCCCCCCCCCC
DGAYIIEKIEQLSN
CCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]